Estimation of sensitivity and specificity of site-specific diagnostic tests.

abstract：BACKGROUND:Recent epidemiological studies have shown that individuals with periodontitis have a significantly increased risk of developing coronary heart disease. In addition to conventional risk factors, chronic infection and subsequent production of systemic inflammatory markers may be associated with this increased ...

journal_title：Journal of periodontal research

authors： Yamazaki K,Honda T,Oda T,Ueki-Maruyama K,Nakajima T,Yoshie H,Seymour GJ

更新日期：2005-02-01 00:00:00

abstract：:Bradykinin stimulated production of prostaglandin E2 (PGE2) and the release of 3H-arachidonic acid by gingival fibroblasts in a time- and dose-dependent manner. The effect on PGE2 biosynthesis was seen already after 15 seconds and was maximal after 5 minutes. Several structurally unrelated inhibitors of arachidonic ac...

journal_title：Journal of periodontal research

authors： Modéer T,Ljunggren O,Lerner UH

更新日期：1990-11-01 00:00:00

abstract：:Previous observations suggest that interleukin-1 (IL-1) may play an important role in the progression of periodontitis. In the present study, we investigated whether a cell-associated IL-1 alpha (CAIL-1 alpha) produced in human gingival fibroblasts (HGF) induces biological activities related to the progression of peri...

journal_title：Journal of periodontal research

authors： Okamatsu Y,Kobayashi M,Nishihara T,Hasegawa K

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Recent data have suggested that in the past 15 years there has been a dramatic increase in the incidence of diabetes mellitus in the USA. However, evidence suggests that approximately one-third of diabetes cases remain undiagnosed. Because 60% of Americans see a dentist at least once per year f...

journal_title：Journal of periodontal research

authors： Borrell LN,Kunzel C,Lamster I,Lalla E

更新日期：2007-12-01 00:00:00

abstract：:This study was designed to study wound strength at the dentine/connective tissue interface and at the bone/connective tissue interface following full thickness flap surgery. Flaps of uniform dimension were outlined in four young adult beagle dogs using a standardised double bladed knife and vertical incisions 10 mm ap...

journal_title：Journal of periodontal research

authors： Werfully S,Areibi G,Toner M,Bergquist J,Walker J,Renvert S,Claffey N

更新日期：2002-10-01 00:00:00

abstract：:This study compared a rapid, colorimetric DNA probe assay designed to be performed in a dental office within 40 min, with anaerobic culture and indirect immunofluorescence microscopy (IFM) for detection of Bacteroides forsythus and Porphyromonas gingivalis in subgingival plaque samples. The DNA probe assay used the Pe...

journal_title：Journal of periodontal research

authors： Tanner AC,Maiden MF,Zambon JJ,Thoren GS,Kent RL Jr

更新日期：1998-02-01 00:00:00

abstract：:The distribution of collagen types I and III was demonstrated in healthy periodontal tissues of the rat and marmoset using immunofluorescent localization after decalcification of the maxillae and mandiblae in 0.2 N HCl. An intense fluorescence in the alveolar bone and cementum matrix, as well as in the soft periodonta...

journal_title：Journal of periodontal research

authors： Romanos GE,Schröter-Kermani C,Hinz N,Wachtel HC,Bernimoulin JP

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Activated potassium channels were found to be strongly correlated with gingival overgrowth (GO) phenotype as we reviewed syndromic hereditary gingival fibromatosis (HGF). Nevertheless, the functional roles of potassium channels in gingival fibrosis or gingival overgrowth remained uncovered. The...

journal_title：Journal of periodontal research

authors： Gao Q,Yang C,Meng L,Wang Z,Chen D,Peng Y,Yang K,Bian Z

更新日期：2020-12-31 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Biofilm formation occurs through the events of cooperative growth and competitive survival among multiple species. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans are important periodontal pathogens. The aim of this study was to demonstrate competitive or cooperative interact...

journal_title：Journal of periodontal research

authors： Takasaki K,Fujise O,Miura M,Hamachi T,Maeda K

更新日期：2013-06-01 00:00:00

abstract：:Hereditary gingival fibromatosis (HGF) is an oral condition characterized by the enlargement of the gingiva of both the maxilla and mandible. To study the cell proliferation index of fibroblasts from HGF and normal gingiva (NG), cell cultures from 4 members of the same family with HGF and from 4 healthy patients were ...

journal_title：Journal of periodontal research

authors： Coletta RD,Almeida OP,Graner E,Page RC,Bozzo L

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to evaluate the effects of increased oxygen availability on gene expression and on collagen deposition/maturation in the periodontium following disease. MATERIAL AND METHODS:Male Wistar rats had ligatures placed around their molars to induce periodontal disease, and a...

journal_title：Journal of periodontal research

authors： Gajendrareddy PK,Junges R,Cygan G,Zhao Y,Marucha PT,Engeland CG

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Neutrophils are the primary white blood cells that are recruited to fight the initial phases of microbial infections. While healthy norms have been determined for circulating blood neutrophil counts in order to identify patients with suspected systemic infections, the levels of oral neutrophils...

journal_title：Journal of periodontal research

authors： Landzberg M,Doering H,Aboodi GM,Tenenbaum HC,Glogauer M

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to evaluate the effect of radiotherapy on the osseointegration of dental implants in the tibia and the action of platelet-rich plasma (PRP) as an adjuvant therapy. MATERIAL AND METHODS:A total of 18 rabbits received two implants in each tibial epiphysis, totalizing 7...

journal_title：Journal of periodontal research

authors： Ocaña RP,Rabelo GD,Sassi LM,Rodrigues VP,Alves FA

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Porphyromonas gingivalis lipopolysaccharide (LPS) is a ligand for cell surface toll-like receptors (TLR), TLR2 and TLR4 while stimulation of either leads to cardioprotection. We hypothesized that: (1) pretreatment with P. gingivalis LPS at appropriate concentrations would induce cardioprotectio...

journal_title：Journal of periodontal research

authors： Fan MH,Wong KL,Wu S,Leung WK,Yam WC,Wong TM

更新日期：2010-02-01 00:00:00

abstract：:Recent reports suggest that specific serum IgG subclasses are a feature of several forms of periodontitis. GCF antibodies are both serum-derived and locally produced by the abundant plasma cells of the diseased periodontal tissue. Previous work has shown that crevicular fluid (GCF) levels of IgG may be reduced in acti...

journal_title：Journal of periodontal research

authors： Kinane DF,Takahashi K,Mooney J

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to design a tripolyphosphate-chitosan cross-linked tetracycline-containing (TPP-TC) sponge that slowly releases tetracycline, for future periodontal applications. MATERIAL AND METHODS:Chitosan sponge was made by freezing and drying 2.5% chitosan solution. Tripolyphosp...

journal_title：Journal of periodontal research

authors： Shen EC,Wang C,Fu E,Chiang CY,Chen TT,Nieh S

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The transplantation of cell sheets of mesenchymal stem cells (MSCs) is expected to be the next generation of periodontal regenerative therapy. An adequate method of multilayering MSCs has yet to be established. When cell sheets proliferate, they usually contract and detach from culture dishes a...

journal_title：Journal of periodontal research

authors： Nakamura K,Yoshimura A,Kaneko T,Sato K,Hara Y

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to investigate reactions of periodontal ligament epithelial cell clusters and major histocompatibility complex class II (OX6)-immunopositive cells to simultaneously induced tooth movement and periodontitis employing Waldo's method. MATERIAL AND METHODS:Elastic gums we...

journal_title：Journal of periodontal research

authors： Tadokoro O,Kawahara I,Vandevska-Radunovic V

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Treponema denticola is a key pathogen associated with periodontitis, a chronic inflammatory disease affecting tooth-supporting tissues. In the present study, we investigated the response of human macrophage-like cells to stimulation by peptidoglycan isolated from T. denticola. We also studied t...

journal_title：Journal of periodontal research

authors： Tanabe SI,Bodet C,Grenier D

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Aggregatibacter actinomycetemcomitans is one of the etiological pathogens implicated in the onset of periodontal disease. This pathogen produces cytolethal distending toxin (CDT) that acts as a genotoxin to induce cell cycle arrest and cellular distension in cultured cell lines. Therefore, CDT is a possible ...

journal_title：Journal of periodontal research

authors： Ohara M,Miyauchi M,Tsuruda K,Takata T,Sugai M

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Proinflammatory cytokines such as interleukin-1beta are known to be synthesized in oral gingivitis and periodontitis and lead to the activation of the transcription factor nuclear factor-kappaB (NF-kappaB). Although numerous effects of interleukin-1beta on mesenchymal cells are known, e.g. up-regu...

journal_title：Journal of periodontal research

authors： Steinberg T,Dannewitz B,Tomakidi P,Hoheisel JD,Müssig E,Kohl A,Nees M

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The gingiva is the first oral tissue directly exposed to cigarette smoke (CS). Exposure to CS compromises the structure and function of gingival tissue. Damaging or altering the gingival epithelium leads to a compromised protective barrier of the periodontium, resulting in several diseases. The...

journal_title：Journal of periodontal research

authors： Alharbi IA,Rouabhia M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Retinoic acid (RA) exerts a wide variety of effects on development, cellular differentiation and homeostasis in various tissues. However, little is known about the effects of RA on the differentiation of periodontal ligament cells. In this study, we investigated whether RA can affect the dexam...

journal_title：Journal of periodontal research

authors： Shibuya N,Nemoto E,Kanaya S,Kunii R,Shimauchi H

更新日期：2005-12-01 00:00:00

abstract：:The matrix metalloproteinases (MMPs) collagenase, gelatinase A (72 kDa gelatinase), stromelysin, and their specific inhibitor TIMP-1 (tissue inhibitor of metalloproteinases), were immunolocalized using specific polyclonal antisera in gingival tissues from 21 patients with chronic inflammatory periodontal disease. Mono...

journal_title：Journal of periodontal research

authors： Meikle MC,Hembry RM,Holley J,Horton C,McFarlane CG,Reynolds JJ

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVES:Chronic periodontitis is a bone destructive inflammatory disease with an adverse impact on general health and suggested underlying factors in common with osteoporosis. A few studies have examined the possible relationship between chronic periodontitis and osteoporosis; however, the results remain inconclusiv...

journal_title：Journal of periodontal research

authors： Mau LP,Kuan YC,Tsai YC,Lin JJ,Huynh-Ba G,Weng PW,Shieh YS,Cheng WC,Huang RY

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Current epidemiological works have suggested that chronic infections, such as periodontitis, are associated with an increased risk of cardiovascular diseases, including hypertrophy and heart failure. However, mechanisms behind the association are not known. The aim of this study was to evaluate...

journal_title：Journal of periodontal research

authors： Köse O,Arabacı T,Gedikli S,Eminoglu DÖ,Kermen E,Kızıldağ A,Kara A,Ozkanlar S,Yemenoglu H

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To ascertain whether interdental cleaning behaviours of Australian adults were associated with lower levels of plaque, gingivitis and periodontal disease. MATERIAL AND METHODS:Data were obtained from the National Survey of Adult Oral Health 2004-06. Outcome variables were three indicators of o...

journal_title：Journal of periodontal research

authors： Crocombe LA,Brennan DS,Slade GD,Loc DO

更新日期：2012-04-01 00:00:00

abstract：:Bursts of periodontal destruction are modelled as percolation-driven phase shift events. Percolation theory, though widely used to study the flow of liquids through porous nonliving materials (e.g., soils and rocks), can be applied to bacterial or toxicological penetration of living tissue in only an approximate sense...

journal_title：Journal of periodontal research

authors： Cohen ME

更新日期：1993-11-01 00:00:00

abstract：:It has been estimated that half the annual health care budget in the United States is spent on patients suffering from tissue loss and late stage organ failure. Critical limitations inherent in traditional therapies call for novel tissue and organ replacement strategies. This paper discusses development of biomaterial...

journal_title：Journal of periodontal research

authors： Murphy WL,Mooney DJ

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Aggregatibacter actinomycetemcomitans is involved in oral and systemic infections, and is associated with, eg aggressive forms of periodontitis and with endocarditis. The cagE gene encodes a ≈39 kDa putative exotoxin expressed by A. actinomycetemcomitans. The level of conservation of cagE, and ...

journal_title：Journal of periodontal research

authors： Johansson A,Claesson R,Höglund Åberg C,Haubek D,Oscarsson J

更新日期：2017-10-01 00:00:00