Is all-rac-alpha-tocopherol different from RRR-alpha-tocopherol regarding cardiovascular efficacy? A meta-analysis of clinical trials.

Abstract:

:A meta-analysis of 14 clinical studies with RRR- or all-rac-alpha-tocopherol (83,800 subjects) was performed to evaluate whether RRR and all-rac differ in cardiovascular efficacy based on those clinical endpoints that are most consistently documented in the publications of the studies. Odds ratios of treatment versus control for individual studies and for studies pooled by form were centered around unity, with no significant differences between vitamin E forms. The results corroborate the present opinion that vitamin E supplements up to 800 mg/d for up to 6.5 years are safe.

journal_name

Ann N Y Acad Sci

authors

Kraemer K,Koch W,Hoppe PP

doi

10.1196/annals.1331.066

subject

Has Abstract

pub_date

2004-12-01 00:00:00

pages

435-8

eissn

0077-8923

issn

1749-6632

pii

1031/1/435

journal_volume

1031

pub_type

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