Gamma-glutamyl-carboxylated Gas6 mediates positive role of vitamin K on lowering hyperglycemia in type 2 diabetes.

abstract：:There is increasing evidence that food is an important factor that influences and shapes the composition and configuration of the gut microbiota. Most studies have focused on macronutrients (fat, carbohydrate, protein) in particular and their effects on the gut microbiota. Although the microbiota can synthesize differ...

journal_title：Annals of the New York Academy of Sciences

authors： Biesalski HK

更新日期：2016-05-01 00:00:00

abstract：:The scientific investigation of brains of different vertebrates, both extant and extinct, is of interest for several reasons: for translating medical research on rodent models into practice, for understanding the animals investigated in order to improve conservation and management strategies, and for understanding the...

journal_title：Annals of the New York Academy of Sciences

authors： Manger PR

更新日期：2011-05-01 00:00:00

abstract：:The objectives of ExoMars are to inject an orbiter around Mars and to land a rover on the surface to look for possible traces of life. During the first stages of the feasibility analysis, the mass margin of the orbiter was very small for a direct transfer in the Soyuz/Fregat scenario. An analysis of the combined use o...

journal_title：Annals of the New York Academy of Sciences

authors： Gil-Fernández J,Van Damme CC,Graziano M,Amata GB,Cogo F,Perino MA

更新日期：2005-12-01 00:00:00

abstract：:Although tissue injury can evoke significant hyperalgesia in infants from the first days of life, little is known about how injury affects emergent central pain networks at the synaptic level. Recent studies have investigated whether tissue damage at different ages has distinct consequences for synaptic function in th...

journal_title：Annals of the New York Academy of Sciences

authors： Baccei ML

更新日期：2010-06-01 00:00:00

abstract：:Growth and pubertal disturbances are the commonest endocrinopathies in homozygous thalassemia, accounting for significant morbidity in 70-80% children and adolescents globally. This review focuses on the pathophysiology of the endocrinopathy from a historical perspective and altered natural history induced by better c...

journal_title：Annals of the New York Academy of Sciences

authors： Chatterjee R,Bajoria R

更新日期：2010-08-01 00:00:00

abstract：:Toluene, a volatile hydrocarbon found in a variety of chemical compounds, is misused and abused by inhalation for its euphorigenic effects. Toluene's reinforcing properties may share a common characteristic with other drugs of abuse, namely, activation of the mesolimbic dopamine system. Prior studies in our laboratory...

journal_title：Annals of the New York Academy of Sciences

authors： Riegel AC,Ali SF,Torinese S,French ED

更新日期：2004-10-01 00:00:00

abstract：:Anatomic and electrophysiologic studies have provided evidence that CRF meets some of the criteria as a neurotransmitter in the noradrenergic nucleus, the locus coeruleus (LC), although some of the criteria have yet to be satisfied. Thus, immunohistochemical findings suggest that CRF innervates the LC, but this must b...

journal_title：Annals of the New York Academy of Sciences

authors： Valentino RJ,Foote SL,Page ME

更新日期：1993-10-29 00:00:00

abstract：:The new vogue for systems biology is an important development. It is time to complement reductionist molecular biology by integrative approaches. But this welcome development is in danger of losing its way. Many of the early implementations of the approach are very low level, in some cases hardly more than an extensio...

journal_title：Annals of the New York Academy of Sciences

authors： Noble D

更新日期：2008-03-01 00:00:00

abstract：:Recognizing the self-activity of matter through complexification can lead to seeing evolution as a process of union. This process approach emphasizes a metaphysics of becoming rather than of being. Advances in the science of thermodynamics lead to understanding chemical self-organization as a stage in this process of ...

journal_title：Annals of the New York Academy of Sciences

authors： Salmon JF

更新日期：2003-05-01 00:00:00

abstract：:In the current study, we examined the effects of minocycline on the osteopenia of ovariectomized (OVX) aged rats using the marrow ablation model. This injury induces rapid bone formation followed by bone resorption in the marrow cavity. Old female rats were randomly divided into five groups: sham, OVX, OVX + minocycli...

journal_title：Annals of the New York Academy of Sciences

authors： Williams S,Barnes J,Wakisaka A,Ogasa H,Liang CT

更新日期：1999-06-30 00:00:00

abstract：:Clinical and experimental gerontologists are extremely interested in lipoproteins as well as in new methods for investigating and probing the apolipoprotein pattern. Using immunofixation electrophoresis, we separated free apolipoprotein A-1 from the apo A-1 associated with high-density lipoproteins. Free apolipoprotei...

journal_title：Annals of the New York Academy of Sciences

authors： Giunta S,Maddalena-Peruzzi A,Gaudio MR,Semprini A

更新日期：1992-12-26 00:00:00

abstract：:Interleukin (IL)-11 is a member of the gp130 family of cytokines. Comparison of IL-11 with another gp130 family member, IL-6, indicates that these two cytokines share many overlapping signal transduction mechanisms. However, unlike IL-6, treatment of patients with a recombinant human form of IL-11 (rhIL-11) does not i...

journal_title：Annals of the New York Academy of Sciences

authors： Trepicchio WL,Dorner AJ

更新日期：1998-09-29 00:00:00

abstract：:Communication by chemical (pheromone) signals is important in many species, including mammals. Chemosensory and hormonal systems can interact in at least two ways: (i) chemosensory input, especially but not exclusively that through the vomeronasal organ, may elicit hormonal release, which, in turn, may facilitate beha...

journal_title：Annals of the New York Academy of Sciences

authors： McClintock MK

更新日期：1998-11-30 00:00:00

abstract：:Despite intense efforts, little is known about the etiology of prostate cancer, and treatment of advanced forms of the disease has had limited success. Nonetheless, epidemiologic studies combined with animal model and in vitro experiments indicate that natural components of the diet, including n-3 PUFA, the carotenoid...

journal_title：Annals of the New York Academy of Sciences

authors： Cohen LA

更新日期：2002-06-01 00:00:00

abstract：:In the frame of the free-radical hypothesis of aging and literature data on increased life span of mated animals, we evaluated brain, kidney, and liver lipid peroxidation in C57Bl/6J mice of various ages and compared lipid peroxidation activity in mated and non-mated mice of both genders. An aging-associated increase ...

journal_title：Annals of the New York Academy of Sciences

authors： Oxenkrug GF,Requintina PJ

更新日期：2003-05-01 00:00:00

abstract：:We have heard a wide-ranging set of talks on cosmology and high energy astrophysics at this conference. All I can really do in this short talk is to present my subjective impression of an arbitrary selection of highlights. ...

journal_title：Annals of the New York Academy of Sciences

authors： Rees MJ

更新日期：1993-06-01 00:00:00

abstract：:The purpose of this study was to determine the seroprevalence against Bartonella henselae and Bartonella quintana among a risk group, patients with HIV infection, and to identify the epidemiological factors involved. Our data indicate that the prevalence of Bartonella infection among HIV-infected patients is much grea...

journal_title：Annals of the New York Academy of Sciences

authors： Pape M,Kollaras P,Mandraveli K,Tsona A,Metallidis S,Nikolaidis P,Alexiou-Daniel S

更新日期：2005-12-01 00:00:00

abstract：:Basal phagocytosis of neutrophils, a crucial component of non-specific immunity, is an eminently circadian parameter. In mice and rats, rates of phagocytosis peak in the second half of the dark span. A lipopolysaccharide-induced phagocytic response challenged in this period appears the most significant in amplitude an...

journal_title：Annals of the New York Academy of Sciences

authors： Hriscu ML

更新日期：2005-12-01 00:00:00

abstract：:Because of the relatively high prevalence of both hepatitis C virus (HCV) infection and autoimmune disorders (ADs), it is not rare to encounter in daily clinical practice patients with ADs also carrying HCV. Corticosteroids and/or immunosuppressant drugs are needed to treat ADs, but they place HCV-infected patients at...

journal_title：Annals of the New York Academy of Sciences

authors： Galeazzi M,Bellisai F,Giannitti C,Manganelli S,Morozzi G,Sebastiani GD

更新日期：2007-09-01 00:00:00

abstract：:Endometrial carcinoma is the most common cancer of the female reproductive organs in the United States. International comparisons reveal that the incidence of endometrial cancer vary widely between different countries with the highest rates observed in North America and Northern Europe, intermediate rates in Eastern E...

journal_title：Annals of the New York Academy of Sciences

authors： Akhmedkhanov A,Zeleniuch-Jacquotte A,Toniolo P

更新日期：2001-09-01 00:00:00

abstract：:In the late 1970s, Wally Welker and his colleagues published a series of papers describing the first high-resolution physiological maps of tactile mossy fiber projections to the granule cell layer of the rat. Over the subsequent decade, his laboratory continued to explore the implications of these results for cerebell...

journal_title：Annals of the New York Academy of Sciences

authors： Bower JM

更新日期：2011-04-01 00:00:00

abstract：:The coordinated regulation between cellular glucose uptake and endogenous glucose production is indispensable for the maintenance of constant blood glucose concentrations. The liver contributes significantly to this process by altering the levels of hepatic glucose release, through controlling the processes of de novo...

journal_title：Annals of the New York Academy of Sciences

authors： Hatting M,Tavares CDJ,Sharabi K,Rines AK,Puigserver P

更新日期：2018-01-01 00:00:00

abstract：:Fibrinogen, a clottable plasma glycoprotein, participates in cell adhesion phenomena involving prokaryotic cells, e.g. staphylococci, and eukaryotic cell fragments, e.g. platelets. Among the three chains (alpha, beta, gamma) of human fibrinogen, the gamma chain bears the main site recognizing the staphylococcal clumpi...

journal_title：Annals of the New York Academy of Sciences

authors： Hawiger J,Kloczewiak M,Timmons S,Strong D,Doolittle RF

更新日期：1983-06-27 00:00:00

abstract：:Bacteria can exhibit high levels of resistance to one or more environmental stresses such as temperature, osmolarity, radiation, pH, starvation, as well as resistance to noxious chemicals and antibiotics. Yet evolution has not optimized stress resistance in all bacteria to all stresses. Even within a species like Esch...

journal_title：Annals of the New York Academy of Sciences

authors： Ferenci T,Spira B

更新日期：2007-10-01 00:00:00

abstract：:Tissue engineering (TE) approaches are being widely investigated for repair of focal defects in articular cartilage. However, the amount and/or type of extracellular matrix (ECM) produced in engineered constructs does not always correlate with the resultant mechanical properties. This could be related to the specifics...

journal_title：Annals of the New York Academy of Sciences

authors： Karchner JP,Querido W,Kandel S,Pleshko N

更新日期：2019-04-01 00:00:00

abstract：:We present our achievements in the synthesis and application of multifunctionalized, cross-linked, polystyrene microspheres, which remarkably and quite generally are taken up by all cell types studied to date. Importantly, the nature of these synthetic beads allows multistep solid-phase chemistry and the ability to bi...

journal_title：Annals of the New York Academy of Sciences

authors： Sánchez-Martín RM,Alexander L,Bradley M

更新日期：2008-01-01 00:00:00

abstract：:Zoonoses are animal and human diseases. Q fever is primarily a zoonosis-an animal disease that can be transmitted to humans under certain conditions. Recent epidemiological studies suggest that Q fever should be considered as a public health problem in many countries where it is present, but unrecognizable due to inad...

journal_title：Annals of the New York Academy of Sciences

authors： Beslagić E,Hamzić S,Beslagić O,Zvizdić S

更新日期：2006-10-01 00:00:00

abstract：:The extreme toxicity of organophosphorous-based compounds has been known since the late 1930s. Starting in the mid-1940s, many nations throughout the world have been producing large quantities of organophosphorous (OP) nerve agents. Huge stockpiles of nerve agents have since developed. There are reportedly more than 2...

journal_title：Annals of the New York Academy of Sciences

authors： LeJeune KE,Dravis BC,Yang F,Hetro AD,Doctor BP,Russell AJ

更新日期：1998-12-13 00:00:00

abstract：:Vitamin E is essential for normal neurological function. It is the major lipid-soluble, chain-breaking antioxidant in the body, protecting the integrity of membranes by inhibiting lipid peroxidation. Mostly on the basis of symptoms of primary vitamin E deficiency, it has been demonstrated that vitamin E has a central ...

journal_title：Annals of the New York Academy of Sciences

authors： Sen CK,Khanna S,Roy S

更新日期：2004-12-01 00:00:00

abstract：:Moderated by Lisa Miller from Newsweek, evolutionary biologist Kenneth Miller (Brown University) and theologians John Haught (Georgetown University) and Nancey Murphy (Fuller Theological Seminary) discuss the questions Are we immortal? Do our souls exist beyond our bodies? and What scientific evidence is there for mys...

journal_title：Annals of the New York Academy of Sciences

authors： Miller L,Miller K,Haught J,Murphy N

更新日期：2011-10-01 00:00:00