On-road assessment of driving performance in bilateral vestibular-deficient patients.

abstract：:The prevalence of obesity is rapidly increasing in the United States, particularly among women. Approximately 60-70% of hypertension in adults may be directly attributed to obesity. In addition, maternal obesity is a major risk factor for hypertensive disorders during pregnancy. The underlying mechanisms for the assoc...

journal_title：Annals of the New York Academy of Sciences

authors： Fu Q

更新日期：2019-10-01 00:00:00

abstract：:We have presented a perspective of progress in three areas of simulations of complex molecules: the development of force fields for molecular simulation; the application of computer graphics, molecular mechanics and molecular dynamics in simulations of DNA and DNA-drug complexes and the application of computer graphic...

journal_title：Annals of the New York Academy of Sciences

authors： Kollman PA,Weiner S,Seibel G,Lybrand T,Singh UC,Caldwell J,Rao SN

更新日期：1986-01-01 00:00:00

abstract：:The human organism is in a state of dynamic equilibrium, homeostasis. The stress system is activated when homeostasis is challenged by extrinsic or intrinsic forces, the stressors. This system, whose central component is the central nervous system (CNS) and includes corticotropin-releasing hormone (CRH) and noradrener...

journal_title：Annals of the New York Academy of Sciences

authors： Stratakis CA,Chrousos GP

更新日期：1995-12-29 00:00:00

abstract：:Local activation of macrophages may play an important role in the immune process of pulmonary infections and in the inflammatory response of lung allograft rejection. To document macrophage activation within human lung allografts displaying various complications, we have investigated ICAM-1 expression in freshly isola...

journal_title：Annals of the New York Academy of Sciences

authors： Fattal-German M,Le Roy Ladurie F,Lecerf F,Berrih-Aknin S

更新日期：1996-10-31 00:00:00

abstract：:Our recently developed method, TranSIESTA, enables modelling of molecular electronic devices under operation conditions. The method is based on density functional theory, and calculates the self-consistent electronic structure of a nanostructure coupled to three-dimensional electrodes with different electrochemical po...

journal_title：Annals of the New York Academy of Sciences

authors： Stokbro K,Taylor J,Brandbyge M,Ordejón P

更新日期：2003-12-01 00:00:00

abstract：:The validity of waist circumference and sagittal diameter as surrogate measures of visceral fat were assessed using preliminary cross-sectional data from the Health, Aging and Body Composition Study, a cohort of 3,075 men and women aged 70-79. Weight, body mass index, waist circumference, waist/thigh ratio, and sagitt...

journal_title：Annals of the New York Academy of Sciences

authors： Harris TB,Visser M,Everhart J,Cauley J,Tylavsky F,Fuerst T,Zamboni M,Taaffe D,Resnick HE,Scherzinger A,Nevitt M

更新日期：2000-05-01 00:00:00

abstract：:Bioterrorism includes possible use of Weapons of Mass Destruction (WMD), preferably biological agents, by non-state terrorist groups as well as criminal clusters. The threat from terrorists to utilize biological agents to achieve goals is not new, but the threshold to realize the threats seems to be lower than previou...

journal_title：Annals of the New York Academy of Sciences

authors： Sandström G

更新日期：2000-01-01 00:00:00

abstract：:Inflammasomes continue to generate interest in an increasing number of disciplines owing to their unique ability to integrate a myriad of signals from pathogen- and damage-associated molecular patterns into a proinflammatory response. This potent caspase-1-dependent process is capable of activating the innate immune s...

journal_title：Annals of the New York Academy of Sciences

authors： Sutterwala FS,Haasken S,Cassel SL

更新日期：2014-06-01 00:00:00

abstract：:Alzheimer's disease (AD) impairs olfaction, but it is uncertain how early this occurs in the disease process and whether the effect can be accounted for by other behavioral or genetic markers of the disease. We administered the Brief Smell Identification Test (BSIT) to 471 older people without dementia or cognitive im...

journal_title：Annals of the New York Academy of Sciences

authors： Wilson RS,Arnold SE,Schneider JA,Boyle PA,Buchman AS,Bennett DA

更新日期：2009-07-01 00:00:00

abstract：:Locomotion control uses proprioceptive, visual, and vestibular signals. Previously, we analyzed the visual contribution with visual motion stimulation in roll while participants kept their heads in a normal upright orientation. In this study we applied the same visual disturbance in a head-upright and a nose-down cond...

journal_title：Annals of the New York Academy of Sciences

authors： Bardins S,Schneider E

更新日期：2009-05-01 00:00:00

abstract：:The hypothalamic-pituitary-adrenocortical (HPA) axis is a major neuroendocrine system involved in the regulation of numerous physiological processes and in adaptation to stress. A wide range of variability can be observed in all the components of the system, and the contribution of genetic factors has been shown in th...

journal_title：Annals of the New York Academy of Sciences

authors： Mormede P,Foury A,Barat P,Corcuff JB,Terenina E,Marissal-Arvy N,Moisan MP

更新日期：2011-03-01 00:00:00

abstract：:The Pawtucket Heart Health Program, a research effort testing a process of community activation for cardiovascular risk factor behavior change, risk factor change, and coronary heart disease event rate change, utilizes risk factor behavior change programs for the entire population of a northeastern city. A diversity o...

journal_title：Annals of the New York Academy of Sciences

authors： Carleton RA,Sennett L,Gans KM,Levin S,Lefebvre C,Lasater TM

更新日期：1991-01-01 00:00:00

abstract：:Between 4 and 13% of people with schizophrenia commit suicide and between 25 and 50% make a suicide attempt, a reflection of the devastating toll this syndrome takes on the quality of life, that is, the subjective and objective sense of well-being. Many risk factors for suicide in schizophrenia have been identified, t...

journal_title：Annals of the New York Academy of Sciences

authors： Meltzer HY

更新日期：2001-04-01 00:00:00

abstract：:Despite the great strides made in understanding the basic biology of cancer and the multiple approaches to cancer therapy that have been utilized, cancer remains a major cause of death worldwide. The two properties that define the most successful tumors are low antigenicity, enabling cancer cells to escape immune syst...

journal_title：Annals of the New York Academy of Sciences

authors： Al-Ramadi BK,Fernandez-Cabezudo MJ,El-Hasasna H,Al-Salam S,Attoub S,Xu D,Chouaib S

更新日期：2008-09-01 00:00:00

abstract：:While the ovaries are the principal source of systemic estrogen in the premenopausal nonpregnant woman, other sites of estrogen biosynthesis are present throughout the body and these become the major sources of estrogen beyond menopause. These extragonadal sources of estrogen are small, but may play an important, thou...

journal_title：Annals of the New York Academy of Sciences

authors： Simpson ER,Clyne C,Speed C,Rubin G,Bulun S

更新日期：2001-12-01 00:00:00

abstract：:The glucocorticoid receptor (GR) is crucial for the effects of glucocorticoids (GCs). Several polymorphisms of the GR are associated with altered sensitivity to GCs. For the ER22/23EK polymorphism, a relative GC resistance has been demonstrated. In vivo, this was suggested by a smaller response to a dexamethasone supp...

journal_title：Annals of the New York Academy of Sciences

authors： Manenschijn L,van den Akker EL,Lamberts SW,van Rossum EF

更新日期：2009-10-01 00:00:00

abstract：:The scientific investigation of brains of different vertebrates, both extant and extinct, is of interest for several reasons: for translating medical research on rodent models into practice, for understanding the animals investigated in order to improve conservation and management strategies, and for understanding the...

journal_title：Annals of the New York Academy of Sciences

authors： Manger PR

更新日期：2011-05-01 00:00:00

abstract：:BALB/c mice infected with Rowson-Parr virus, a lymphatic leukemia virus isolated from the Friend complex, undergo a rapid depression of antibody response. Spleen cells from these mice in culture show a similar deficit in the response to stimulation with sheep red cells and inhibit the reactivity of normal splenocytes....

journal_title：Annals of the New York Academy of Sciences

authors： Bendinelli M,Toniolo A

更新日期：1976-01-01 00:00:00

abstract：:Thymic pathology occurs in 80-90% of myasthenia gravis patients. Significant associations between different thymic alterations and clinical findings are discussed. To highlight peculiarities in thymoma-associated myasthenia gravis, we briefly review myasthenia gravis associated with thymic lymphofollicular hyperplasia...

journal_title：Annals of the New York Academy of Sciences

authors： Marx A,Müller-Hermelink HK,Ströbel P

更新日期：2003-09-01 00:00:00

abstract：:The presented paper describes a multi-disciplinary cooling selection approach applied to major gas turbine engine hot section components, including turbine nozzles, blades, discs, combustors and support structures, which maintain blade tip clearances. The paper demonstrates benefits of close interaction between partic...

journal_title：Annals of the New York Academy of Sciences

authors： Glezer B

更新日期：2001-05-01 00:00:00

abstract：:Various biological activities of peptides have been found. In this study, the induction of apoptosis in a human lymphoma cell line (U937) by peptide fraction separated from anchovy sauce was studied using biochemical and flow cytometric methods. After U937 was treated with a hydrophobic peptide fraction of the anchovy...

journal_title：Annals of the New York Academy of Sciences

authors： Lee YG,Kim JY,Lee KW,Kim KH,Lee HJ

更新日期：2003-12-01 00:00:00

abstract：:Factors that regulate various pathways of Maillard reaction leading to aroma, color, or carcinogen generation have not been identified, due to the difficulties associated with analyzing complex reaction mixtures. In particular, the role played by oxidation in directing aromagenic, chromogenic, or carcinogenic pathways...

journal_title：Annals of the New York Academy of Sciences

authors： Yaylayan VA,Haffenden L,Chu FL,Wnorowski A

更新日期：2005-06-01 00:00:00

abstract：:The dentate gyrus of the rat forms in three developmental phases, each of which is characterized by neuronal birth, migration and death. Recent evidence indicates that adrenal steroids regulate neuronal birth, death, and possibly migration throughout the life of the animal. However, the observation that very few neuro...

journal_title：Annals of the New York Academy of Sciences

authors： Gould E

更新日期：1994-11-14 00:00:00

abstract：:During the annual Ramazzini Days, the Mayor of Carpi confers the Ramazzini Award on scientists deemed by the Collegium Ramazzini to have made outstanding contributions to furthering the aims of Bernardino Ramazzini in safeguarding public health. Dr. Lorenzo Tomatis was the Ramazzini Award recipient in 2005, and the pr...

journal_title：Annals of the New York Academy of Sciences

authors： Tomatis L

更新日期：2006-09-01 00:00:00

abstract：:Tick-borne pathogens in the genus Ehrlichia cause emerging zoonoses. Although laboratory mice are susceptible to Ehrlichia infections, many isolates do not cause clinical illness. In contrast, the Ixodes ovatus Ehrlichia-like agent (IOE) causes disease and immune responses in mice comparable to the human illness cause...

journal_title：Annals of the New York Academy of Sciences

authors： Munderloh UG,Silverman DJ,MacNamara KC,Ahlstrand GG,Chatterjee M,Winslow GM

更新日期：2009-05-01 00:00:00

abstract：:The elderly, often defined as those 65 years or older, are the most rapidly growing segment of the population, and onset of epilepsy is higher in this age group than in any other. This paper reviews recent developments, including a new proposed definition of epilepsy, a transgenic mouse model of Alzheimer's disease th...

journal_title：Annals of the New York Academy of Sciences

authors： Leppik IE,Birnbaum AK

更新日期：2010-01-01 00:00:00

abstract：:Based on the relation found to exist between low CSF 5-HIAA and suicide attempt, in particular violent suicide attempt, both in depressed and in so-called nondepressed suicide attempters, the conclusion was drawn that decreased central 5-HT metabolism is related to (auto)aggression, rather than to depression. We chall...

journal_title：Annals of the New York Academy of Sciences

authors： Van Praag HM,Plutchik R,Conte H

更新日期：1986-01-01 00:00:00

abstract：:Growing evidence from clinical and epidemiological studies points to a synchronized increase in the incidence of male reproductive problems, such as genital abnormalities, testicular cancer, reduced semen quality, and subfertility. Together these male reproductive problems may reflect the existence of one common entit...

journal_title：Annals of the New York Academy of Sciences

authors： Boisen KA,Main KM,Rajpert-De Meyts E,Skakkebaek NE

更新日期：2001-12-01 00:00:00

abstract：:The perceptions of coccidioidomycosis as a medical problem has undergone sequential and dramatic metamorphoses since its first description more than a century ago. First thought to be rare and lethal, coccidioidomycosis was subsequently found to be common and often mild. During World War II, its overall impact upon la...

journal_title：Annals of the New York Academy of Sciences

authors： Galgiani JN

更新日期：2007-09-01 00:00:00

abstract：:Within the past few years, developmental scientists have switched their attention from the study of DNA sequencing to the epigenetic state of the genome. Studying epigenetics could present the key to understanding gene expression changes without altering the basic structure of DNA. For example, the blastocyst, trophec...

journal_title：Annals of the New York Academy of Sciences

authors： Palini S,De Stefani S,Scala V,Dusi L,Bulletti C

更新日期：2011-03-01 00:00:00