The polerovirus minor capsid protein determines vector specificity and intestinal tropism in the aphid.

abstract：:The Vif protein of human immunodeficiency virus type 1 (HIV-1) is important for virion infectivity. Previous studies have shown that vif-defective virions exhibit structural abnormalities in the virus core and are defective in the ability to complete proviral DNA synthesis in acutely infected cells. We developed novel...

journal_title：Journal of virology

authors： Ohagen A,Gabuzda D

更新日期：2000-12-01 00:00:00

abstract：:The sodium dodecyl sulfate (SDS) complex of the major glycoprotein of avian myeloblastosis virus exhibited an anomalously low free electrophoretic mobility compared with those of non-glycosylated protein standards. The apparent molecular weight of the glycoprotein calculated from the relation between log molecular wei...

journal_title：Journal of virology

authors： Marciani DJ,Papamatheakis JD

更新日期：1978-06-01 00:00:00

abstract：:Fluorosulfonylbenzoyl 5'-adenosine (FSBA) bound to one site in simian virus 40 large T antigen (T) and covalently modified greater than 95% of the molecules in a complete reaction. This analog for ATP specifically cross-links to the Mg-phosphate pocket in ATP-binding sites. Cyanogen bromide cleavage and tryptic digest...

journal_title：Journal of virology

authors： Bradley MK

更新日期：1990-10-01 00:00:00

abstract：:Crimean-Congo hemorrhagic fever virus (CCHFV), a member of the genus Nairovirus of the family Bunyaviridae, causes severe disease with high rates of mortality in humans. The CCHFV M RNA segment encodes the virus glycoproteins G(N) and G(C). To understand the processing and intracellular localization of the CCHFV glyco...

journal_title：Journal of virology

authors： Bertolotti-Ciarlet A,Smith J,Strecker K,Paragas J,Altamura LA,McFalls JM,Frias-Stäheli N,García-Sastre A,Schmaljohn CS,Doms RW

更新日期：2005-05-01 00:00:00

abstract：:Translation of aphthovirus RNA is initiated at an internal ribosome entry site (IRES) element, preceding the first functional AUG initiation codon. The effect of mutations at the base of domain 3 of the aphthovirus IRES on translation activity has been analyzed by site-directed mutagenesis and expression of bicistroni...

journal_title：Journal of virology

authors： Martínez-Salas E,Regalado MP,Domingo E

更新日期：1996-02-01 00:00:00

abstract：:Interferon (IFN) is an important immune system molecule capable of inducing an antiviral state within cells. Herpes simplex virus type 1 (HSV-1) replication is somewhat reduced in tissue culture in the presence of IFN, presumably due to decreased viral transcription. Here, we show mutations that inactivate immediate-e...

journal_title：Journal of virology

authors： Mossman KL,Saffran HA,Smiley JR

更新日期：2000-02-01 00:00:00

abstract：:The ability of HIV-1 to establish a latent infection presents a barrier to curing HIV. The best-studied reservoir of latent virus in vivo is resting memory CD4(+) T cells, but it has recently been shown that CD34(+) hematopoietic progenitor cells (HPCs) can also become latently infected by HIV-1 in vitro and in vivo. ...

journal_title：Journal of virology

authors： McNamara LA,Ganesh JA,Collins KL

更新日期：2012-09-01 00:00:00

abstract：:One characteristic of all positive-strand RNA viruses is the necessity to assemble viral RNA replication complexes on host intracellular membranes, a process whose molecular details are poorly understood. To study viral replication complex assembly we use the established model system of Flock House virus (FHV), which ...

journal_title：Journal of virology

authors： Stapleford KA,Rapaport D,Miller DJ

更新日期：2009-05-01 00:00:00

abstract：:Nonenveloped gastrointestinal viruses, such as human rotavirus, can exit infected cells from the apical surface without cell lysis. The mechanism of such nonlytic exit is poorly understood. The nonenveloped Orsay virus is an RNA virus infecting the intestine cells of the nematode Caenorhabditis elegans Dye staining re...

journal_title：Journal of virology

authors： Yuan W,Zhou Y,Fan Y,Tao YJ,Zhong W

更新日期：2018-06-29 00:00:00

abstract：:The relative contribution of measles virus hemagglutinin (H)- or fusion protein (F)-specific antibodies to virus neutralization (VN) has not been demonstrated. We have depleted these specific antibodies from sera collected from young adults, who had been vaccinated during childhood, by prolonged incubation with viable...

journal_title：Journal of virology

authors： de Swart RL,Yüksel S,Osterhaus AD

更新日期：2005-09-01 00:00:00

abstract：:The proline-rich tandem repeat domain of human mucin MUC1 forms an extended structure containing large repeating loops that are crested by a turn. We show that the repeating-loop structure of MUC1 can be replaced by an antibody complementarity-determining region loop of a human immunodeficiency virus type 1 (HIV-1)-sp...

journal_title：Journal of virology

authors： Fontenot JD,Zacharopoulos VR,Phillips DM

更新日期：1996-10-01 00:00:00

abstract：UNLABELLED:To investigate the molecular mechanism(s) by which herpes simplex virus 1 (HSV-1) tegument protein UL51 promotes viral replication, we screened for viral proteins that interact with UL51 in infected cells. Affinity purification of tagged UL51 in HSV-1-infected Vero cells was coupled with immunoblotting of th...

journal_title：Journal of virology

authors： Oda S,Arii J,Koyanagi N,Kato A,Kawaguchi Y

更新日期：2016-09-12 00:00:00

abstract：:The v-src coding region was deleted from cloned Rous sarcoma virus DNA, and the deleted clones were tested for infectivity by transfection. All of the coding region, as well as most of the sequences lying between v-src and the unique 3' region (U3), could be deleted without affecting viability. However, at least 9 and...

journal_title：Journal of virology

authors： Sorge J,Hughes SH

更新日期：1982-08-01 00:00:00

abstract：:The generation of cytopathic effects by murine leukemia viruses (MLVs) in different cell types correlates with the ability of the virus to induce thymic lymphoma. We showed that the induction of apoptosis in mink epithelial cells by mink cell focus-forming (MCF) MLV infection results in the accumulation of high levels...

journal_title：Journal of virology

authors： Zhao X,Yoshimura FK

更新日期：2008-03-01 00:00:00

abstract：:F111 rat cells transformed by simian virus 40 mutant tsA1499 are cold sensitive for the expression of transformation. Yet, unlike F111 cells transformed by tsA58, they do not lose the ability to stabilize the transformation-associated host cell protein p53 at the temperature at which transformation is extinguished. ...

journal_title：Journal of virology

authors： Bouck N,Fikes J,Rundell MK

更新日期：1984-03-01 00:00:00

abstract：:RNA editing of the hepatitis delta virus (HDV) antigenome at the amber/W site by the host RNA adenosine deaminase ADAR1 is a critical step in the HDV replication cycle. Editing is required for production of the viral protein hepatitis delta antigen long form (HDAg-L), which is necessary for viral particle production b...

journal_title：Journal of virology

authors： Jayan GC,Casey JL

更新日期：2005-09-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) infection of monocyte-derived macrophages (MDM) results in delayed and nonlytic productive viral growth. During late stages of replication, infectious virus remains cell associated in cytoplasmic vacuoles. In order to understand HCMV survival and persistence in MDM, we examined mechanisms ...

journal_title：Journal of virology

authors： Fish KN,Britt W,Nelson JA

更新日期：1996-03-01 00:00:00

abstract：:Many viruses induce type I interferon responses by activating cytoplasmic RNA sensors, including the RIG-I-like receptors (RLRs). Although two members of the RLR family, RIG-I and MDA5, have been implicated in host control of virus infection, the relative role of each RLR in restricting pathogenesis in vivo remains un...

journal_title：Journal of virology

authors： Lazear HM,Pinto AK,Ramos HJ,Vick SC,Shrestha B,Suthar MS,Gale M Jr,Diamond MS

更新日期：2013-11-01 00:00:00

abstract：:The involvement of the mouse mammary tumor virus (MTV) in spontaneous and hormone-induced mammary tumors in low-mammary-tumor mouse strains was studied by comparing the amounts of MTV RNA and MTV DNA sequences in mammary tumors and other tissues of mice with an without hormonal treatments. The following results were o...

journal_title：Journal of virology

authors： Michalides R,van Deemter L,Nusse R,Röpcke G,Boot L

更新日期：1978-09-01 00:00:00

abstract：:Human metapneumovirus (HMPV) has recently been identified as a significant cause of serious respiratory tract disease in humans. In particular, the emerging information on the contribution of HMPV to pediatric respiratory tract disease suggests that it will be important to develop a vaccine against this virus for use ...

journal_title：Journal of virology

authors： Biacchesi S,Skiadopoulos MH,Yang L,Lamirande EW,Tran KC,Murphy BR,Collins PL,Buchholz UJ

更新日期：2004-12-01 00:00:00

abstract：:Bovine herpesvirus 1 (BHV-1) establishes a latent infection in sensory ganglionic neurons of cattle. During a latent infection, a single latency-related (LR) transcript is expressed. This observation suggested that DNA sequences in the LR promoter are positively regulated by neural cell type factors. The regulation of...

journal_title：Journal of virology

authors： Bratanich AC,Jones CJ

更新日期：1992-10-01 00:00:00

abstract：:Retrovirus replication requires the production of both spliced and unspliced viral RNA from a single RNA transcript. In contrast, cellular RNA precursors with introns almost completely spliced. The cis elements and virus-coded trans factors which determine the extent to which Rous sarcoma virus RNA is spliced to src m...

journal_title：Journal of virology

authors： Stoltzfus CM,Fogarty SJ

更新日期：1989-04-01 00:00:00

abstract：:The recognition of naturally occurring rhadinoviruses in macaque monkeys has spurred interest in their use as models for human infection with Kaposi sarcoma-associated herpesvirus (human herpesvirus 8). Rhesus macaques (Macaca mulatta) and pig-tailed macaques (Macaca nemestrina) were inoculated intravenously with rhad...

journal_title：Journal of virology

authors： Mansfield KG,Westmoreland SV,DeBakker CD,Czajak S,Lackner AA,Desrosiers RC

更新日期：1999-12-01 00:00:00

abstract：:We have designed a ribozyme that cleaves human immunodeficiency virus type 1 (HIV-1) RNA in U5 (at nucleotide +115). This ribozyme was tested in vitro and was found to give efficient and specific digestion of RNA containing the HIV-1 U5 sequence. When the U5 ribozyme was placed into the HIV-1 genome, virus replication...

journal_title：Journal of virology

authors： Dropulić B,Lin NH,Martin MA,Jeang KT

更新日期：1992-03-01 00:00:00

abstract：UNLABELLED:A bat virus with high phylogenetic relatedness to human mumps virus (MuV) was identified recently at the nucleic acid level. We analyzed the functional activities of the hemagglutinin-neuraminidase (HN) and the fusion (F) proteins of the bat virus (batMuV) and compared them to the respective proteins of a hu...

journal_title：Journal of virology

authors： Krüger N,Hoffmann M,Drexler JF,Müller MA,Corman VM,Sauder C,Rubin S,He B,Örvell C,Drosten C,Herrler G

更新日期：2015-04-01 00:00:00

abstract：:Replication of poliovirus (PV) is restricted to a few sites, including the brain and spinal cord. However, this neurotropism is not conserved in cultured cells. Monkey kidney cells become susceptible to PV infection after cultivation in vitro, and cell lines of monolayer cultures from almost any tissue of primates are...

journal_title：Journal of virology

authors： Yoshikawa T,Iwasaki T,Ida-Hosonuma M,Yoneyama M,Fujita T,Horie H,Miyazawa M,Abe S,Simizu B,Koike S

更新日期：2006-05-01 00:00:00

abstract：:Of the numerous endogenous retroviral elements that are present in the human genome, the abundant HERV-K family is distinct because several members are transcriptionally active and coding for biologically active proteins. A detailed phylogeny of the HERV-K family based on the partial sequence of the reverse transcript...

journal_title：Journal of virology

authors： Berkhout B,Jebbink M,Zsíros J

更新日期：1999-03-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) possesses low pathogenic potential in an immunocompetent host. In the immunosuppressed host, however, a wide spectrum of infection outcomes, ranging from asymptomatic to life threatening, can follow either primary or nonprimary infection. The variability in the manifestations of HCMV infec...

journal_title：Journal of virology

authors： Sequar G,Britt WJ,Lakeman FD,Lockridge KM,Tarara RP,Canfield DR,Zhou SS,Gardner MB,Barry PA

更新日期：2002-08-01 00:00:00

abstract：:The unfolded-protein response (UPR), activated by sensor molecules PERK, ATF6, and IRE1 to resolve endoplasmic reticulum (ER) stress, has emerged as a key target for host cells and viruses to control the infection outcomes. The UPR regulates ER protein folding, controls cell fate upon ER stress, and plays an important...

journal_title：Journal of virology

authors： Qian Z,Xuan B,Chapa TJ,Gualberto N,Yu D

更新日期：2012-06-01 00:00:00

abstract：:The genome of the Snyder-Theilen strain of feline sarcoma virus (ST-FeSV) is a 4.3-kilobase-pair (kbp) RNA molecule that contains a 1.5-kbp cellular insertion (fes gene) flanked by feline leukemia virus sequences at its 5' end (1.6 kbp) and 3' end (1.2 kbp) (Sherr et al., J. Virol. 34:200-212, 1980). DNA transfection ...

journal_title：Journal of virology

authors： Barbacid M

更新日期：1981-01-01 00:00:00