Cellular transformation by subgenomic feline sarcoma virus DNA.

abstract：UNLABELLED:Increasing data suggest that NK cells can mediate antiviral activity in HIV-1-infected humans, and as such, novel approaches harnessing the anti-HIV-1 function of both T cells and NK cells represent attractive options to improve future HIV-1 immunotherapies. Chronic progressive HIV-1 infection has been assoc...

journal_title：Journal of virology

authors： Jost S,Tomezsko PJ,Rands K,Toth I,Lichterfeld M,Gandhi RT,Altfeld M

更新日期：2014-08-01 00:00:00

abstract：:Infection with human T-cell leukemia virus type I (HTLV-I) is associated with adult T-cell lymphoma/leukemia. This disease occurs in only a small minority of people infected with HTLV-I and manifests itself many years after infection. Therefore, it appears that a fine balance exists between HTLV-I and the host T-cell ...

journal_title：Journal of virology

authors： Clark NM,Smith MJ,Hilfinger JM,Markovitz DM

更新日期：1993-09-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) infection causes the active degradation of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs), and this process is reliant on the expression of the HSV-1 immediate-early protein Vmw110. In this study we investigated in more detail the mechanism by which the degradation...

journal_title：Journal of virology

authors： Parkinson J,Lees-Miller SP,Everett RD

更新日期：1999-01-01 00:00:00

abstract：:During the 2009 H1N1 influenza virus pandemic (pdmH1N1) outbreak, it was found that most individuals lacked antibodies against the new pdmH1N1 virus, and only the elderly showed anti-hemagglutinin (anti-HA) antibodies that were cross-reactive with the new strains. Different studies have demonstrated that prior contact...

journal_title：Journal of virology

authors： Fang Y,Banner D,Kelvin AA,Huang SS,Paige CJ,Corfe SA,Kane KP,Bleackley RC,Rowe T,Leon AJ,Kelvin DJ

更新日期：2012-02-01 00:00:00

abstract：:The recent advent of genome sequences as the only source available to classify many newly discovered viruses challenges the development of virus taxonomy by expert virologists who traditionally rely on extensive virus characterization. In this proof-of-principle study, we address this issue by presenting a computation...

journal_title：Journal of virology

authors： Lauber C,Gorbalenya AE

更新日期：2012-04-01 00:00:00

abstract：:Bacteriophage T4 gene 32 encodes a DNA unwinding protein required for DNA replication, repair, and recombination. Gene 32 temperature-sensitive mutations enhance virtually all base pair substitution mutation rates. ...

journal_title：Journal of virology

authors： Koch RE,McGaw MK,Drake JW

更新日期：1976-08-01 00:00:00

abstract：UNLABELLED:Retargeting of gammaretroviral envelope proteins has shown promising results in the isolation of novel isolates with therapeutic potential. However, the optimal conditions required to obtain high-affinity retargeted envelope proteins with narrow tropism are not understood. This study highlights the advantage...

journal_title：Journal of virology

authors： Valdivieso-Torres L,Sarangi A,Whidby J,Marcotrigiano J,Roth MJ

更新日期：2015-12-30 00:00:00

abstract：:We have previously described several helper independent vector constructions (S. Hughes and E. Kosik, Virology 136:89-99, 1984; J. Sorge and S. H. Hughes, J. Mol. Appl. Genet. 1:547-599, 1982; J. Sorge, B. Ricci, and S. Hughes, J. Virol. 48:667-675, 1983), all of which derive from Rous sarcoma virus. In this report we...

journal_title：Journal of virology

authors： Hughes SH,Greenhouse JJ,Petropoulos CJ,Sutrave P

更新日期：1987-10-01 00:00:00

abstract：:Plasma from a small subset of subjects chronically infected with HIV-1 shows remarkable magnitude and breadth of neutralizing activity. From one of these individuals (CH0219), we isolated two broadly neutralizing antibodies (bnAbs), CH01 and VRC-CH31, from two clonal lineages of memory B cells with distinct specificit...

journal_title：Journal of virology

authors： Bonsignori M,Montefiori DC,Wu X,Chen X,Hwang KK,Tsao CY,Kozink DM,Parks RJ,Tomaras GD,Crump JA,Kapiga SH,Sam NE,Kwong PD,Kepler TB,Liao HX,Mascola JR,Haynes BF

更新日期：2012-04-01 00:00:00

abstract：:In vitro transcription of the avian tumor virus RNA by RNA-directed DNA polymerase is initiated on the unique cellular 4S RNA. Previous studies have shown that on the average there is one such RNA primer hydrogen bonded to each viral 35S RNA. The present study confirms that finding and demonstrates that, at least for ...

journal_title：Journal of virology

authors： Taylor JM,Illmensee R

更新日期：1975-09-01 00:00:00

abstract：:A mutant which produces a small-headed ("petite") variant of bacteriophage T4 is described. The mutation (E920g) maps in a new gene (66) between genes 23 and 24. Petite phage particles composed up to 70% of the phage yield. The petite phage was nonviable upon single infection but produced progeny when two or more infe...

journal_title：Journal of virology

authors： Eiserling FA,Geiduschek EP,Epstein RH,Metter EJ

更新日期：1970-12-01 00:00:00

abstract：:Escherichia coli K-12 wild type and a uvrA mutant derivative were used to construct isogenic strains bearing one, two, three, or more phage lambda cI genomes and containing increasing concentration of lambda repressor as measured by in vitro operator DNA-binding assays. The survival and phage induction in response to ...

journal_title：Journal of virology

authors： Baluch J,Sussman R

更新日期：1978-06-01 00:00:00

abstract：:Human immunodeficiency virus type 1 infection of mononuclear phagocytes has been implicated in disease manifestations, but postentry viral replication events in these cells have not been well characterized. Productive infection of activated T cells is associated with cell proliferation and accumulation of full-length ...

journal_title：Journal of virology

authors： O'Brien WA,Namazi A,Kalhor H,Mao SH,Zack JA,Chen IS

更新日期：1994-02-01 00:00:00

abstract：:Lymphomas induced by the Abelson murine leukemia virus (A-MuLV) were examined for the expression of biochemical and biological markers associated with A-MuLV transformation before and after in vivo growth in genetically distinguishable host mice. Although all tumors and clonal lines derived from them initially express...

journal_title：Journal of virology

authors： Grunwald DJ,Dale B,Dudley J,Lamph W,Sugden B,Ozanne B,Risser R

更新日期：1982-07-01 00:00:00

abstract：:ts1 and ts7, two temperature-sensitive mutants of Moloney murine leukemia virus strain TB induce hind-limb paralysis in 100% of CFW/D mice injected. These two paralytogenic mutants also share a defect in their inability to process the env precursor protein, Pr80env, at the restrictive temperature. To identify the muta...

journal_title：Journal of virology

authors： Yuen PH,Malehorn D,Knupp C,Wong PK

更新日期：1985-05-01 00:00:00

abstract：:Zika virus (ZIKV), a mosquito-transmitted flavivirus, is linked to microcephaly and other neurological defects in neonates and Guillain-Barré syndrome in adults. The molecular mechanisms regulating ZIKV infection and pathogenic outcomes are incompletely understood. Signaling by the mechanistic (mammalian) target of ra...

journal_title：Journal of virology

authors： Sahoo BR,Pattnaik A,Annamalai AS,Franco R,Pattnaik AK

更新日期：2020-10-27 00:00:00

abstract：:We molecularly cloned the src coding region of tsNY68, a mutant of Rous sarcoma virus temperature sensitive (ts) for transformation, and constructed a series of ts wild-type recombinant src genes. DNA containing the hybrid genes was transfected into chicken cells together with viral vector DNA and helper viral DNA, an...

journal_title：Journal of virology

authors： Nishizawa M,Mayer BJ,Takeya T,Yamamoto T,Toyoshima K,Hanafusa H,Kawai S

更新日期：1985-12-01 00:00:00

abstract：:Posttranscriptional gene silencing (PTGS), a homology-dependent RNA degradation system, has a role in defending against virus infection in plants, but plant viruses encode a suppressor to combat PTGS. Using transgenic tobacco in which the expression of green fluorescent protein (GFP) is posttranscriptionally silenced,...

journal_title：Journal of virology

authors： Kubota K,Tsuda S,Tamai A,Meshi T

更新日期：2003-10-01 00:00:00

abstract：:In this study, we investigated the expression levels of host restriction factors in six untreated HIV-1-positive patients over the course of infection. We found that the host restriction factor gene expression profile consistently increased over time and was significantly associated with CD4+ T cell activation and vir...

journal_title：Journal of virology

authors： Raposo RA,Abdel-Mohsen M,Deng X,Hecht FM,Pilcher CD,Pillai SK,Nixon DF

更新日期：2014-10-01 00:00:00

abstract：:Immunosuppressed patients are at risk for developing Epstein-Barr Virus (EBV)-positive lymphomas that express the major EBV oncoprotein, LMP1. Although increasing evidence suggests that a small number of lytically infected cells may promote EBV-positive lymphomas, the impact of enhanced lytic gene expression on the ab...

journal_title：Journal of virology

authors： Ma SD,Yu X,Mertz JE,Gumperz JE,Reinheim E,Zhou Y,Tang W,Burlingham WJ,Gulley ML,Kenney SC

更新日期：2012-08-01 00:00:00

abstract：:Hepatitis C virus (HCV) chronic infection is characterized by low-level or undetectable cellular immune responses against HCV antigens. HCV proteins have been shown to affect various intracellular events and modulate immune responses, although the precise mechanisms used to mediate these effects are not fully understo...

journal_title：Journal of virology

authors： Saito K,Ait-Goughoulte M,Truscott SM,Meyer K,Blazevic A,Abate G,Ray RB,Hoft DF,Ray R

更新日期：2008-04-01 00:00:00

abstract：:Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The HTLV-1 genome encodes the Tax protein that plays essential regulatory roles in HTLV-1 replication and oncogenic transformation of T lymphocytes....

journal_title：Journal of virology

authors： Gao L,Harhaj EW

更新日期：2013-12-01 00:00:00

abstract：:The membrane-proximal region of the human immunodeficiency virus type 1 (HIV-1) transmembrane protein (TM) is critical for envelope (Env)-mediated membrane fusion and contains the target for broadly reactive neutralizing antibody 2F5. It has been proposed that 2F5 neutralization might involve interaction of its long, ...

journal_title：Journal of virology

authors： Ou W,Lu N,Yu SS,Silver J

更新日期：2006-03-01 00:00:00

abstract：:The cloned murine cytolytic T-lymphocyte line IE1-IL and several sublines detect a murine cytomegalovirus immediate-early (IE) membrane determinant in conjunction with Ld class I major histocompatibility glycoprotein. The lines retained cytolytic activity, strict antigen specificity, and self-restriction even when ada...

journal_title：Journal of virology

authors： Reddehase MJ,Fibi MR,Keil GM,Koszinowski UH

更新日期：1986-12-01 00:00:00

abstract：:Tetherin (CD317/BST-2), an interferon-induced membrane protein, restricts the release of nascent retroviral particles from infected cell surfaces. While human immunodeficiency virus type 1 (HIV-1) encodes the accessory gene vpu to overcome the action of tetherin, the lineage of primate lentiviruses that gave rise to H...

journal_title：Journal of virology

authors： Le Tortorec A,Neil SJ

更新日期：2009-11-01 00:00:00

abstract：:Temperature-sensitive (ts) mutants were isolated from the baculovirus Autographa californica (alfalfa looper) MNPV, grown in Spodoptera frugiperda (fall armyworm) cells in the presence of N-methyl-N'-nitro-N-nitrosoguanidine. Of 567 plaque isolates screened, 27 were temperature sensitive (ts), representing a mutation ...

journal_title：Journal of virology

authors： Brown M,Crawford AM,Faulkner P

更新日期：1979-07-01 00:00:00

abstract：:The bovine leukemia virus (BLV) is an oncogenic retrovirus that is associated with the development of persistent lymphocytosis (PL) and lymphoma in cattle. While B lymphocytes have been shown to be the primary cellular target of BLV, recent studies suggest that some T lymphocytes and monocytes may be infected by the v...

journal_title：Journal of virology

authors： Mirsky ML,Olmstead CA,Da Y,Lewin HA

更新日期：1996-04-01 00:00:00

abstract：:The murine polyomavirus (Py) enters mouse fibroblasts and kidney epithelial cells via an endocytic pathway that is caveola-independent (as well as clathrin-independent). In contrast, uptake of simian virus 40 into the same cells is dependent on caveola. Following the initial uptake of Py, both microtubules and microfi...

journal_title：Journal of virology

authors： Gilbert JM,Goldberg IG,Benjamin TL

更新日期：2003-02-01 00:00:00

abstract：:The vaccinia virus H5 gene encodes a 22.3-kDa phosphoprotein that is expressed during both the early and late phases of viral gene expression. It is a major component of virosomes and has been implicated in viral transcription and, as a substrate of the B1 kinase, may participate in genome replication. To enable a gen...

journal_title：Journal of virology

authors： DeMasi J,Traktman P

更新日期：2000-03-01 00:00:00

abstract：:Particular interest in human T lymphocyte lymphoma/leukemia virus (HTLV) derives from the close association of HTLV with several types of human mature T lymphocyte malignancies and the strong possibility that HTLV is the causative agent of this group of leukemias and lymphomas. This is the first report to show that HT...

journal_title：Journal of virology

authors： Moore JL,Poiesz BJ,Zamkoff KW,Merl SA,Hanna S,Gazdar AF,Comis RL

更新日期：1985-02-01 00:00:00