Inverse relationship between constitutive gamma interferon production and human T-cell lymphoma/leukemia virus expression in cultured T lymphocytes.

abstract：:In most prion diseases, infectivity accumulates in lymphoreticular organs early after infection. Defects in hematopoietic compartments, such as impaired B-cell maturation, or in stromal compartments, such as abrogation of follicular dendritic cells, can delay or prevent lymphoreticular prion colonization. However, the...

journal_title：Journal of virology

authors： Kaeser PS,Klein MA,Schwarz P,Aguzzi A

更新日期：2001-08-01 00:00:00

abstract：UNLABELLED:Cattle have been proposed as the natural reservoir of a novel member of the virus family Orthomyxoviridae, which has been tentatively classified as influenza D virus (IDV). Although isolated from sick animals, it is unclear whether IDV causes any clinical disease in cattle. To address this aspect of Koch's p...

journal_title：Journal of virology

authors： Ferguson L,Olivier AK,Genova S,Epperson WB,Smith DR,Schneider L,Barton K,McCuan K,Webby RJ,Wan XF

更新日期：2016-05-27 00:00:00

abstract：:Tetherin (CD317/BST-2), an interferon-induced membrane protein, restricts the release of nascent retroviral particles from infected cell surfaces. While human immunodeficiency virus type 1 (HIV-1) encodes the accessory gene vpu to overcome the action of tetherin, the lineage of primate lentiviruses that gave rise to H...

journal_title：Journal of virology

authors： Le Tortorec A,Neil SJ

更新日期：2009-11-01 00:00:00

abstract：:Canine parvovirus type 2 (CPV-2) is a severe enteric pathogen of dogs, causing high mortality in unvaccinated dogs. After emerging, CPV-2 spread rapidly worldwide. However, there is now some evidence to suggest that international transmission appears to be more restricted. In order to investigate the transmission and ...

journal_title：Journal of virology

authors： Clegg SR,Coyne KP,Parker J,Dawson S,Godsall SA,Pinchbeck G,Cripps PJ,Gaskell RM,Radford AD

更新日期：2011-08-01 00:00:00

abstract：:Prestimulation of the TLR4 pathway with lipopolysaccharide (LPS) protects mice from lethal infection with H5N1 influenza virus. Here, we reveal that the TLR4-TRIF pathway is required for this protective effect by using mice whose TLR4-related molecules were knocked out. Microarray analysis of primary mouse lung cultur...

journal_title：Journal of virology

authors： Shinya K,Ito M,Makino A,Tanaka M,Miyake K,Eisfeld AJ,Kawaoka Y

更新日期：2012-01-01 00:00:00

abstract：:The retroviral Gag protein plays the central role in the assembly process and can form membrane-enclosed, virus-like particles in the absence of any other viral products. These particles are similar to authentic virions in density and size. Three small domains of the human immunodeficiency virus type 1 (HIV-1) Gag pro...

journal_title：Journal of virology

authors： Garnier L,Ratner L,Rovinski B,Cao SX,Wills JW

更新日期：1998-06-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) (also called human herpesvirus 8) is consistently found in Kaposi's sarcoma lesions and in body-cavity-based lymphomas. A 17-kb KSHV lambda clone was obtained directly from a Kaposi's sarcoma lesion. DNA sequence analysis of this clone identified an open reading frame whi...

journal_title：Journal of virology

authors： Li M,Lee H,Yoon DW,Albrecht JC,Fleckenstein B,Neipel F,Jung JU

更新日期：1997-03-01 00:00:00

abstract：:Neutralizing antibodies may have critical importance in immunity against human immunodeficiency virus type 1 (HIV-1) infection. However, the amount of protective antibody needed at mucosal surfaces has not been fully established. Here, we evaluated systemic and mucosal pharmacokinetics (PK) and pharmacodynamics (PD) o...

journal_title：Journal of virology

authors： Klein K,Veazey RS,Warrier R,Hraber P,Doyle-Meyers LA,Buffa V,Liao HX,Haynes BF,Shaw GM,Shattock RJ

更新日期：2013-11-01 00:00:00

abstract：:Poliovirus-specific T lymphocytes were isolated from virus-immunized mice of different H-2 haplotypes. Immunological characterization of this population indicates that the effector population involved in the observed poliovirus-specific proliferative response was that of CD4-positive T-helper cells. Proliferative resp...

journal_title：Journal of virology

authors： Kutubuddin M,Simons J,Chow M

更新日期：1992-05-01 00:00:00

abstract：:Active proteinase 3C of hepatitis A virus (HAV) was expressed in bacteria either as a mature enzyme or as a protein fused to the entire polymerase 3D or to a part of it, and their identities were shown by immunoblot analysis. Intermolecular cleavage activity was demonstrated by incubating in vitro-translated and radio...

journal_title：Journal of virology

authors： Kusov YY,Sommergruber W,Schreiber M,Gauss-Müller V

更新日期：1992-11-01 00:00:00

abstract：:Unlike RNA viruses, most DNA viruses replicate their genomes with high-fidelity polymerases that rarely make base substitution errors. Nevertheless, experimental evolution studies have revealed rapid acquisition of adaptive mutations during serial passage of attenuated vaccinia virus (VACV). One way in which adaptatio...

journal_title：Journal of virology

authors： Senkevich TG,Zhivkoplias EK,Weisberg AS,Moss B

更新日期：2020-08-31 00:00:00

abstract：:The nucleoprotein (NP) of influenza B virus is 50 amino acids longer at the N-terminus than influenza A virus NP and lacks homology to the A virus protein over the first 69 residues. We have deleted the N-terminal 51 and 69 residues of the influenza B/Ann Arbor/1/66 virus NP and show that nuclear accumulation of the p...

journal_title：Journal of virology

authors： Stevens MP,Barclay WS

更新日期：1998-06-01 00:00:00

abstract：:The signaling lymphocyte activation molecule F1 (SLAMF1) is both a microbial sensor and entry receptor for measles virus (MeV). Herein, we describe a new role for SLAMF1 to mediate MeV endocytosis that is in contrast with the alternative, and generally accepted, model that MeV genome enters cells only after fusion at ...

journal_title：Journal of virology

authors： Gonçalves-Carneiro D,McKeating JA,Bailey D

更新日期：2017-03-13 00:00:00

abstract：:The herpesvirus saimiri (HVS) immediate-early gene product encoded by open reading frame (ORF) 57 shares limited amino acid homology with HSV-1 ICP27 and Epstein-Barr virus BMLF1, both regulatory proteins. The ORF 57 gene has been proposed to be spliced based on the genome sequence, and here we confirm the intron-exon...

journal_title：Journal of virology

authors： Whitehouse A,Cooper M,Meredith DM

更新日期：1998-01-01 00:00:00

abstract：:It is well established that host genetics, especially major histocompatibility complex (MHC) genes, are important determinants of human immunodeficiency virus disease progression. Studies with simian immunodeficiency virus (SIV)-infected Indian rhesus macaques have associated Mamu-B*17 with control of virus replicatio...

journal_title：Journal of virology

authors： Wojcechowskyj JA,Yant LJ,Wiseman RW,O'Connor SL,O'Connor DH

更新日期：2007-01-01 00:00:00

abstract：:Toroviruses (family Coronaviridae, order Nidovirales) are enveloped, positive-stranded RNA viruses that have been implicated in enteric disease in cattle and possibly in humans. Despite their potential veterinary and clinical relevance, little is known about torovirus epidemiology and molecular genetics. Here, we pres...

journal_title：Journal of virology

authors： Smits SL,Lavazza A,Matiz K,Horzinek MC,Koopmans MP,de Groot RJ

更新日期：2003-09-01 00:00:00

abstract：:Coronaviruses generally have a narrow host range, infecting one or just a few species. Using targeted RNA recombination, we constructed a mutant of the coronavirus mouse hepatitis virus (MHV) in which the ectodomain of the spike glycoprotein (S) was replaced with the highly divergent ectodomain of the S protein of fel...

journal_title：Journal of virology

authors： Kuo L,Godeke GJ,Raamsman MJ,Masters PS,Rottier PJ

更新日期：2000-02-01 00:00:00

abstract：:We examined the migratory properties of the mouse serum protein responsible for specific neutralization of the endogenous mouse xenotropic type C virus and demonstrated that this neutralizing factor can be transferred from mouse lipoproteins to human and to nonreactive mouse lipoproteins. After acceptance of this acti...

journal_title：Journal of virology

authors： Levy JA,Dimpfl J,Hardman D,Kane JP

更新日期：1982-05-01 00:00:00

abstract：:Antibodies against CCR5, the major coreceptor for human immunodeficiency virus type 1 (HIV-1), may have antiviral potential as viral fusion inhibitors. In this study, we generated a virus-like particle (VLP)-based vaccine that effectively breaks B-cell tolerance and elicits autoantibodies against CCR5 in pig-tailed ma...

journal_title：Journal of virology

authors： Chackerian B,Briglio L,Albert PS,Lowy DR,Schiller JT

更新日期：2004-04-01 00:00:00

abstract：:Homo-oligomeric runs were inserted into a spleen necrosis virus-based retrovirus vector to determine the nature and rate of mutations within runs of 10 to 12 identical nucleotides during a single replication cycle. Clones of helper cells containing integrated copies of retroviral vectors were used to produce virus for...

journal_title：Journal of virology

authors： Burns DP,Temin HM

更新日期：1994-07-01 00:00:00

abstract：:A study of virus-specific protein synthesis in infectious pancreatic necrosis virus-infected RTG-2 cells was undertaken to find a relationship between the coding capacity of virus genome (two segments of double-stranded RNA of 2.5 X10(6) and 2.3 X 10(6) molecular weight) and the sizes and relative amounts of polypepti...

journal_title：Journal of virology

authors： Dobos P

更新日期：1977-01-01 00:00:00

abstract：UNLABELLED:HIV-1-specific CD8 T cells can influence HIV-1 disease progression during untreated HIV-1 infection, but the functional and phenotypic properties of HIV-1-specific CD8 T cells in individuals treated with suppressive antiretroviral therapy remain less well understood. Here we show that a subgroup of HIV-1-spe...

journal_title：Journal of virology

authors： Vigano S,Negron J,Ouyang Z,Rosenberg ES,Walker BD,Lichterfeld M,Yu XG

更新日期：2015-08-01 00:00:00

abstract：:We constructed a matched set of plasmids to investigate the interactions of essential core sequences of the simian virus 40 replication origin with flanking regulatory sequences. Deletions of either T-antigen-binding region I or the 21-base-pair repeated promoter elements reduced replication to 50 to 70% of wild-type ...

journal_title：Journal of virology

authors： DeLucia AL,Deb S,Partin K,Tegtmeyer P

更新日期：1986-01-01 00:00:00

abstract：UNLABELLED:Influenza A virus requires ongoing cellular transcription to carry out the cap-snatching process. Chromatin remodelers modify chromatin structure to produce an active or inactive conformation, which enables or prevents the recruitment of transcriptional complexes to specific genes; viral transcription thus d...

journal_title：Journal of virology

authors： Marcos-Villar L,Pazo A,Nieto A

更新日期：2016-01-20 00:00:00

abstract：:Normal replication of Moloney murine leukemia virus (MoMLV) requires the integration of a DNA copy of the viral RNA genome into a chromosome of the host. In this work, we characterize the DNA sequences at the ends of the linear proviral precursor that are required for integration in the presence of MoMLV integration p...

journal_title：Journal of virology

authors： Bushman FD,Craigie R

更新日期：1990-11-01 00:00:00

abstract：:The enzymatic activity of recombinant influenza virus RNA polymerase is strictly dependent on the addition of a template RNA containing 5' and 3' viral sequences. Here we report the analysis of the binding specificity and physical characterization of the complex by using gel shift, modification interference, and densi...

journal_title：Journal of virology

authors： Tiley LS,Hagen M,Matthews JT,Krystal M

更新日期：1994-08-01 00:00:00

abstract：:We report here the complete genomic sequence of the duck Tembusu virus (DTMUV) WJ-1 strain, isolated from Muscovy ducks. This is the first complete genome sequence of DTMUV reported in southern China. Compared with the other strains (TA, GH-2, YY5, and ZJ-407) that were previously found in eastern China, WJ-1 bears a ...

journal_title：Journal of virology

authors： Zhu W,Chen J,Wei C,Wang H,Huang Z,Zhang M,Tang F,Xie J,Liang H,Zhang G,Su S

更新日期：2012-12-01 00:00:00

abstract：:Vesicular stomatitis virus (VSV) is a negative-strand RNA virus with intrinsic oncolytic specificity due to substantially attenuated antiviral responses in many tumors. We have recently reported that recombinant VSV vector can be used as an effective oncolytic agent to safely treat multifocal hepatocellular carcinoma ...

journal_title：Journal of virology

authors： Shinozaki K,Ebert O,Suriawinata A,Thung SN,Woo SL

更新日期：2005-11-01 00:00:00

abstract：:We developed a mouse model of Borna disease to facilitate immunopathogenesis research by adaptation of Borna disease virus to mice through serial passage in mouse brain tissue. Borna disease virus replication, antibody production, inflammation, and Borna disease expression in several different strains of mice were exa...

journal_title：Journal of virology

authors： Rubin SA,Waltrip RW 2nd,Bautista JR,Carbone KM

更新日期：1993-01-01 00:00:00

abstract：:Poliovirus infection of HeLa cells results in a rapid inhibition of host protein synthesis by a mechanism that does not affect the translation of poliovirus RNA. It has been suggested that this virus-induced translational control results from inactivation of the cap-binding protein complex, and it has been shown that ...

journal_title：Journal of virology

authors： Lloyd RE,Jense HG,Ehrenfeld E

更新日期：1987-08-01 00:00:00