Introduction to immune cell signalling.

Abstract:

:The dynamic interaction of cells of the immune system with other cells, antigens and secreted factors determines the nature of an immune response. The response of individual cells is governed by the sequence of intracellular signalling events triggered following the association of cell surface molecules during cell-cell contact or the detection of soluble molecules of host or pathogen origin. In this review we will first outline the general principles of intracellular signal transduction. We will then describe the signalling pathways triggered following the recognition of antigen, as well as the detection of cytokines, and discuss how the signalling pathways activated regulate the effector response.

journal_name

Parasitology

journal_title

Parasitology

authors

Goodridge HS,Harnett MM

doi

10.1017/S0031182005008115

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

S3-9

eissn

0031-1820

issn

1469-8161

pii

S0031182005008115

journal_volume

130 Suppl

pub_type

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