Abstract:
:Comparison of the genomic organization of variola and vaccinia viruses has been carried out. Molecular factors of virulence of these viruses is the focus of this review. Possible roles of the genes of soluble cytokine receptors, complement control proteins, factors of virus replication, and dissemination in vivo for variola virus pathogenesis are discussed. The existence of "buffer" genes in the vaccinia virus genome is proposed.
journal_name
Virus Genesjournal_title
Virus genesauthors
Shchelkunov SNdoi
10.1007/BF01724297subject
Has Abstractpub_date
1995-01-01 00:00:00pages
53-71issue
1eissn
0920-8569issn
1572-994Xjournal_volume
10pub_type
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