Functional organization of variola major and vaccinia virus genomes.

Abstract:

:Comparison of the genomic organization of variola and vaccinia viruses has been carried out. Molecular factors of virulence of these viruses is the focus of this review. Possible roles of the genes of soluble cytokine receptors, complement control proteins, factors of virus replication, and dissemination in vivo for variola virus pathogenesis are discussed. The existence of "buffer" genes in the vaccinia virus genome is proposed.

journal_name

Virus Genes

journal_title

Virus genes

authors

Shchelkunov SN

doi

10.1007/BF01724297

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

53-71

issue

1

eissn

0920-8569

issn

1572-994X

journal_volume

10

pub_type

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