Heterogeneity of the haemoglobin-A1c-band in isoelectric focussing.

Abstract:

:A double HbA1c-band was demonstrated in isoelectric focussing of blood from diabetics with a fasting blood glucose above 11 mmol/l. The same band-doubling was also demonstrated after incubation of erythrocytes in glucose/saline solutions. This finding may reflect the presence of the initial condensation product between haemoglobin and glucose, the Schiff-base intermediate.

journal_name

Diabetologia

journal_title

Diabetologia

authors

Welinder BS,Svendsen PA

doi

10.1007/BF00281827

subject

Has Abstract

pub_date

1980-11-01 00:00:00

pages

465-7

issue

5

eissn

0012-186X

issn

1432-0428

journal_volume

19

pub_type

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