Abstract：
:This article reports the results of 11 generations of selective breeding for isolation-induced, interfemale aggression in Mus musculus. Within-family selection was used to form two high, two low, and two unselected control lines, beginning with a population of wild-trapped mice. Selection was successful in establishing the divergent lines, so that in recent generations about 50% of high-line animals attack, as do 25% of controls and 5% of lows. Realized heritabilities for eight generations of selection were 0.12 for H1, 0.14 for H2, 0.34 for L1, and 0.46 for L2. Male aggression has apparently not shown a correlated response to selection for female aggression. Group housing reduces the aggression of female mice, but the order of the lines is maintained under either isolation or group housing. Practical problems encountered in this selection program are discussed.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Hyde JS,Sawyer TFdoi
10.1007/BF01065597subject
Has Abstractpub_date
1980-07-01 00:00:00pages
349-59issue
4eissn
0001-8244issn
1573-3297journal_volume
10pub_type
杂志文章abstract：:Rhythm of activity of inbred mice was recorded automatically by a set of actographs. This rhythm was characterized by six indices in the temporal and frequency domains. Two methods of genetic analysis were applied to these indices using parental strains BALB/c and C57BL/6, the reciprocal F1's, and the seven recombinan...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01066331
更新日期：1991-03-01 00:00:00
abstract：:Previous studies suggest that brain opioid activity decreases aggression in animal models. The main objective of the current study was to examine the possible genetic relationship between intermale aggression and brain levels of enkephalins, endorphins, and dynorphins in 11 inbred strains of mice. Pursuit, rattling, a...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1025774716976
更新日期：2003-09-01 00:00:00
abstract：:Using high resolution magnetic resonance imaging data, we examined the interrelationships between eight cerebral lobar volumetric measures via both exploratory and confirmatory factor analyses in a large sample (N = 484) of pediatric twins and singletons. These analyses suggest the presence of strong genetic correlati...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-010-9332-6
更新日期：2010-03-01 00:00:00
abstract：:In the course of the East Flanders Prospective Twin Survey (EFPTS), handedness was assessed as part of a genealogical study (Meulemans et al., 1995) in 1616 twins (808 twin pairs) aged 6 to 28. Our findings are that, in this large population-based study with known placentation and zygosity, the often observed higher f...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF02359484
更新日期：1996-07-01 00:00:00
abstract：:Callous-unemotional (CU) traits comprise the core symptoms of psychopathy, yet no study has estimated the heritability of CU traits in a community sample of children using an instrument designed solely to assess CU traits. The current study uses data from 339 twin pairs aged 9-14 to examine the reliability and heritab...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-016-9831-1
更新日期：2017-03-01 00:00:00
abstract：:To study the relationship between genetics and epilepsy, Wistar rats susceptible to audiogenic seizure were selected from the main breeding stock of the Ribeirão Preto School of Medicine at the University of São Paulo, Brazil, and inbred. The criteria for selection were the highest seizure severity index (SI) and shor...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1021099432759
更新日期：2003-01-01 00:00:00
abstract：:Parameter estimates from analyses of univariate twin data usually do not reflect the uncertainty due to the model selection phase of the data analysis. To address the effect of model selection uncertainty on parameter estimates, we introduce frequentist model-averaged estimators for univariate twin data analysis that ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-006-9065-8
更新日期：2006-09-01 00:00:00
abstract：:Two ongoing selective breeding projects have produced mice that display divergent analgesic responses to morphine. These two projects have selected for similar phenotypes: high and low levorphanol analgesia (HAR/LAR lines; Portland, OR) and high and low swim stress-induced analgesia (HA/LA lines; Jastrzebiec, Poland)....
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF02197290
更新日期：1995-07-01 00:00:00
abstract：:Almost 40 years ago, evidence from large studies of adult twins and their relatives suggested that between 30 and 60% of the variance in social and political attitudes could be explained by genetic influences. However, these findings have not been widely accepted or incorporated into the dominant paradigms that explai...
journal_title：Behavior genetics
pub_type： 杂志文章,meta分析
doi：10.1007/s10519-014-9648-8
更新日期：2014-05-01 00:00:00
abstract：:The most common alternative to a genetic explanation of left-handedness is that sinistrality arises because of birth stress factors. In a sample of 1398 subjects, the association between birth stress and left-handedness was confirmed. More importantly, it was found that left-handed mothers are more likely to have birt...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF02327575
更新日期：1995-11-01 00:00:00
abstract：:Based on the reviewed literature and the data presented in this paper, conclusions can be drawn with respect to the validity of the WAG/Rij strain of rats as a model for absence epilepsy in humans. The view that the WAG/Rij model has "face validity" is supported by the simultaneous presence of clinical and electroence...
journal_title：Behavior genetics
pub_type： 杂志文章,评审
doi：10.1023/a:1026179013847
更新日期：2003-11-01 00:00:00
abstract：:Reading difficulties are both heritable and stable; however, little is known about the etiology of this stability. Results from a preliminary analysis of data from 56 twin pairs who participated in the Colorado Longitudinal Twin Study of Reading Disability (Astrom et al., Twin Res Hum Genet 10:434-439, 2007) suggested...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-011-9445-6
更新日期：2011-09-01 00:00:00
abstract：:Genetic strains of mice represent an important resource for research on the biological determinants of complex diseases and behavioral phenotypes. To date, the approaches used have had little success in identifying causal genes. We have evaluated brain gene expression in C57BL/6J (B6) and DBA/2J (D2) inbred mouse stra...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/B:BEGE.0000023648.78190.ee
更新日期：2004-07-01 00:00:00
abstract：:Variance components analysis provides an efficient method for performing linkage analysis for quantitative traits. However, power and type 1 error of variance components-based likelihood ratio testing may be affected when phenotypic data are nonnormally distributed (especially with high values of kurtosis) and there i...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/B:BEGE.0000013729.26354.da
更新日期：2004-03-01 00:00:00
abstract：:Previous animal studies have revealed significant involvement of genetics in nicotine intake; however, the extent of the genetic contribution to this behavior has not been well addressed. We report the first study of nine generations of selection for high and low voluntary nicotine intake in outbred Sprague-Dawley rat...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-013-9605-y
更新日期：2013-09-01 00:00:00
abstract：:Among three sibling species of the D. melanogaster subgroup, two are generalists (D. simulans and D. mauritiana), while the third, D. sechellia, specializes on a single toxic resource, the fruit of Morinda citrifolia. D. sechellia, resistant to the toxics, prefers to oviposit on morinda; D. simulans, which is very sen...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01076179
更新日期：1994-09-01 00:00:00
abstract：:The initial experimental population of Drosophila persimilis was photopositive and slightly geonegative. In this respect, the initial population of D. persimilis differed from the experimental population of D. pseudoobscura, described by others, which was close to photo- and geotactic neutrality. In D. persimilis as i...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01066177
更新日期：1975-07-01 00:00:00
abstract：:In previous electrophysiological experiments from hypopigmented animals (mice, rats, rabbits), single-unit recordings from both retinal ganglion axons and cells in the superior colliculus have demonstrated an increase in threshold in the dark-adapted state which is roughly proportional to the ocular melanin concentrat...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01067442
更新日期：1993-07-01 00:00:00
abstract：:Five species of whale with matrilineal social systems (daughters remain with mothers) have remarkably low levels of mitochondrial DNA diversity. Non-heritable matriline-level demography could reduce genetic diversity but the required conditions are not consistent with the natural histories of the matrilineal whales. T...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-017-9840-8
更新日期：2017-05-01 00:00:00
abstract：:A complimentary two-phase strategy was used to detect and map quantitative trait loci (QTLs) associated with the basal locomotor response to a saline challenge (10 ml/kg). In phase 1, putative QTLs, significant at p < 0.01 or better, were identified by analysis of the strain means for 25 strains of the B x D recombina...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1001963906258
更新日期：2000-05-01 00:00:00
abstract：:Adolescent depression is common and has become a major public health concern in China, yet little research has examined the etiology of depression in Chinese adolescents. In the present study, genetic and environmental influences on Chinese adolescent depressive symptoms were investigated in 1,181 twin pairs residing ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-013-9632-8
更新日期：2014-01-01 00:00:00
abstract：:Selection for geotaxis was carried out with flies from a natural population of Drosophila melanogaster; geotactic behavior was measured by means of a Hirsch classification maze. The population was initally almost neutral to gravity, and it responded to both positive (downward) and negative (upward) selection with a re...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01065679
更新日期：1976-01-01 00:00:00
abstract：:To extend Purcell's well known ACE model in testing gene by measured environment interactions (GxM) in behavior genetic designs, Rathouz et al. considered a broader class of models for quantifying and testing such interactions. Only a sub-group of these extended models have been investigated for their statistical oper...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-015-9710-1
更新日期：2015-07-01 00:00:00
abstract：:Tested in Hirsch-Hadler mazes, Drosophila pseudoobscura is on the average geoneutral and photoneutral. Strongly geo- and photopositive and geo- and photonegative populations can be obtained by artificial selection, but upon relaxation of the selection they tend to relapse toward neutrality. This genetic homeostasis is...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01065728
更新日期：1976-07-01 00:00:00
abstract：:The non-synonymous SNP rs2228145 in the IL6R gene on chromosome 1q21.3 is associated with a wide range of common diseases, including asthma, rheumatoid arthritis, type 1 diabetes and coronary heart disease. We examined the contribution of this functional IL6R gene polymorphism rs2228145 versus other genome-wide SNPs t...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-014-9656-8
更新日期：2014-07-01 00:00:00
abstract：:Complex illnesses, like depression, are thought to arise from the interplay between psychosocial stressors and genetic predispositions. Approaches that take into account both personal and neighborhood factors and that consider gene regions as well as individual SNPs may be necessary to capture these interactions acros...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-015-9734-6
更新日期：2016-01-01 00:00:00
abstract：:We examined longitudinally collected behavioral reports by teachers on a unique twin sample at the ages of 7, 8, 9, 10, 11, and 12 years. As twin and adoption studies implicate the role of genetic influence on behavioral problems found to be stable in epidemiological samples, the current study employs a developmental ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-004-1747-5
更新日期：2005-07-01 00:00:00
abstract：:Testis specific protein, Y-encoded-like 2 (TSPYL2) regulates the expression of genes encoding glutamate receptors. Glutamate pathology is implicated in neurodevelopmental conditions such as autism spectrum disorder, attention deficit hyperactivity disorder (ADHD) and schizophrenia. In line with this, a microduplicatio...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-015-9777-8
更新日期：2016-07-01 00:00:00
abstract：:Effective mapping strategies for quantitative trains must allow for the detection of the more important quantitative trait loci (QTLs) while minimizing false positives. Type I (false-positive) and Type II (false-negative) error rates were estimated from a computer simulation of QTL mapping in the BXD recombinant inbre...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF02359892
更新日期：1996-03-01 00:00:00
abstract：:The facts concerning Kammerer's case are reviewed. Koestler's view that Krammerer was unjustly accused is presented and shown to be incorrect. ...
journal_title：Behavior genetics
pub_type： 传,历史文章,杂志文章
doi：10.1007/BF01066805
更新日期：1975-04-01 00:00:00
