Squid lens cytoskeleton and membrane proteins.

Abstract:

:Cytoskeletal and membrane proteins were isolated from respectively the urea-soluble and urea-insoluble fractions of the squid lens. The main cytoskeletal polypeptide has a molecular weight (63000) and an amino acid composition similar to those of vertebrate intermediate filament proteins, including mammalian lens vimentins. Intermediate filaments, and bundles thereof, were regenerated from the squid lens urea-soluble fraction upon removal of urea. The main membrane polypeptide of 140000 Mr has an amino acid composition entirely different from that of the main intrinsic membrane protein of 26000 Mr which is found in all vertebrates. Although non-EDTA-extractable, the 140000 Mr squid membrane polypeptide is best classified as extrinsic, since it has a high polarity (mainly acidic residues) and can be degraded completely upon trypsin treatment of squid lens membranes.

journal_name

Curr Eye Res

journal_title

Current eye research

authors

Siezen RJ

doi

10.3109/02713688208996358

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

579-89

issue

9

eissn

0271-3683

issn

1460-2202

journal_volume

2

pub_type

杂志文章
  • Point-wise relationships between visual field sensitivity and macular thickness determined by spectral-domain optical coherence tomography.

    abstract:PURPOSE:To evaluate the point-wise relationships between visual field sensitivity (VFS), as measured by standard automated perimetry (SAP), and macular thickness, as determined by spectral-domain optical coherence tomography (SD-OCT), in patients with glaucoma. MATERIALS AND METHODS:One hundred and six glaucoma subjec...

    journal_title:Current eye research

    pub_type: 临床试验,杂志文章

    doi:10.3109/02713683.2013.787433

    authors: Kim JM,Sung KR,Yoo YC,Kim CY

    更新日期:2013-08-01 00:00:00

  • Failure of intravitreal dexamethasone to diminish inflammation or retinal toxicity in an experimental model of Bacillus cereus endophthalmitis.

    abstract:PURPOSE:To determine whether the usual clinical dose of intravitreal dexamethasone can attenuate intraocular inflammation and retinal necrosis in a rabbit model of fulminant Bacillus cereus endophthalmitis induced by crude exotoxins. METHODS:Thirty-six eyes from pigmented mongrel rabbits received intravitreal injectio...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713680490516701

    authors: Pollack JS,Beecher DJ,Pulido JS,Lee Wong AC

    更新日期:2004-10-01 00:00:00

  • Detection of substance P in human tears by laser desorption mass spectrometry and immunoassay.

    abstract:PURPOSE:To determine whether substance P is present in human tears. METHODS:Tear samples (1-2 microliters) were collected from one eye of each of 12 subjects. Two of the eyes had dry eye syndrome, two wore contact lenses and had dry eye syndrome, and eight were normal. Five of the eight normal eyes were scheduled to u...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.16.9.960.5040

    authors: Varnell RJ,Freeman JY,Maitchouk D,Beuerman RW,Gebhardt BM

    更新日期:1997-09-01 00:00:00

  • The effect of prematurity on tear production.

    abstract:PURPOSE:To evaluate the effect of the birth weight and the postconceptional age on the tear production of preterm and term newborn infants and to evaluate the changes in tear production during the first two months of life. SUBJECTS--METHODS: Both eyes of medically stable term and preterm infants were included in the st...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.28.2.145.26235

    authors: Akar Y,Cira A,Apaydin C,Erman MA,Yilmaz A

    更新日期:2004-02-01 00:00:00

  • 24-hour intraocular pressure and blood pressure levels with latanoprost/timolol fixed combination versus timolol.

    abstract:PURPOSE:To evaluate 24-hr intraocular pressure (IOP) and blood pressure (BP) with timolol or latanoprost/timolol fixed combination (LTFC). METHODS:Patients with primary open-angle glaucoma or ocular hypertension with normal blood pressure were randomized to LTFC, dosed each evening, or timolol dosed twice daily in a c...

    journal_title:Current eye research

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/02713680902850075

    authors: Konstas AG,Pikilidou MI,Tsironi S,Mikropoulos D,Kozobolis VP,Sarafidis PA,Lasaridis AN,Nelson LA,Stewart WC

    更新日期:2009-05-01 00:00:00

  • ApoA-I Mimetic Peptide 4F Reduces Age-Related Lipid Deposition in Murine Bruch's Membrane and Causes Its Structural Remodeling.

    abstract:PURPOSE:Accumulation of lipoprotein-derived lipids including esterified and unesterified cholesterol in Bruch's membrane of human eyes is a major age-related change involved in initiating and sustaining soft drusen in age-related macular degeneration (AMD). The apolipoprotein (apo) A-I mimetic peptide 4F is a small ant...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2017.1370118

    authors: Rudolf M,Mir Mohi Sefat A,Miura Y,Tura A,Raasch W,Ranjbar M,Grisanti S,Aherrahrou Z,Wagner A,Messinger JD,Garber DW,Anantharamaiah GM,Curcio CA

    更新日期:2018-01-01 00:00:00

  • Associations among Socioeconomic Factors, Lag Time, and High-Risk Histopathologic Features in Eyes Primarily Enucleated for Retinoblastoma.

    abstract::Purpose/Aim: To determine the associations among socioeconomic factors, delay in management, and high-risk histopathologic features in eyes primarily enucleated for retinoblastoma. Materials and Methods: A single-site survey was conducted from January 2016 through January 2018. Eyes primarily enucleated for unilateral...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2019.1623898

    authors: Xiao W,Ye H,Zeng H,Tang L,Chen R,Gao Y,Mao Y,Yang H

    更新日期:2019-10-01 00:00:00

  • Multivariate Analysis to Predict the Horizontal Anterior Chamber Diameter from Other Anterior Chamber Parameters Using Scheimpflug Imaging: Is There a Better Method Than Adding a Fixed Constant?

    abstract:PURPOSE:To evaluate the predictive association between the horizontal anterior chamber diameter (HACD) and other measurements using Scheimpflug imaging, and to assess whether a method superior to using fixed constants can be proposed. METHODS:This hospital-based study was performed in the Cornea and Refractive Surgery...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2016.1151529

    authors: Prakash G,Philip R,Bacero R,Srivastava D

    更新日期:2017-01-01 00:00:00

  • Photoreceptoral basis for altered dark-adaptation in retinal degeneration (RCS) rats.

    abstract::The 'fast PIII' rod mediated photoreceptor response to flashes of monochromatic light has been investigated in isolated retinae of the RCS rat at age 30 days. A loss of both sensitivity and maximum response amplitude were found, with a concurrent slowing of the response kinetics. These observations indicate a rod abno...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688409000805

    authors: Low JC

    更新日期:1984-09-01 00:00:00

  • Localization of vasoactive intestinal polypeptide and neurotensin immunoreactivities in the avian retina.

    abstract::The distribution of vasoactive intestinal polypeptide (VIP)- and neurotensin (NT)-like immunoreactivities in the chicken retina was investigated by immunohistochemistry. VIP- and NT-positive cells were found throughout the chicken retina. The majority of them were located in the proximal portion of the inner nuclear l...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688109001736

    authors: Fukuda M,Kuwayama Y,Shiosaka S,Inagaki S,Ishimoto I,Shimizu Y,Takagi H,Sakanaka M,Takatsuki K,Senba E,Tohyama M

    更新日期:1981-01-01 00:00:00

  • Efficacy of 9-(2-phosphonylmethoxyethyl)adenine in the therapy of TK+ and TK- herpes simplex virus experimental keratitis.

    abstract::The acyclic nucleoside phosphonate analogue PMEA [9-(2-phosphonylmethoxyethyl)adenine] is a broad spectrum antiviral agent effective against DNA viruses and retroviruses. It is particularly active against the human immunodeficiency virus and, like other phosphonylmethoxyalkyl derivatives, it also inhibits HSV-1, TK- H...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689109020370

    authors: Maudgal PC,De Clercq E

    更新日期:1991-01-01 00:00:00

  • Effect of acyclovir on thermal stress-induced herpesvirus reactivation.

    abstract:PURPOSE:Acyclovir has been shown to be effective in preventing recurrent herpes simplex virus lesions of the genitalia and oral labia. The purpose of the current study was to determine the effect of acyclovir on the appearance of infectious virus in the peripheral nervous system and in an end organ, the eye. MATERIALS...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713680490504560

    authors: Gebhardt BM,Kaufman HE,Hill JM

    更新日期:2004-08-01 00:00:00

  • The Effect of Antiamoebic Agents on Viability, Proliferation and Migration of Human Epithelial Cells, Keratocytes and Endothelial Cells, In Vitro.

    abstract:PURPOSE:To analyze the effect of diamidines (hexamidine-diisethionat (HD), propamidin-isethionate (PD), dibromopropamidine-diisethionat (DD)), and biguanides (polyhexamethylen biguanid (PHMB), chlorhexidine (CH)) on human corneal epithelial cell, keratocyte and endothelial cell viability, proliferation, and migration, ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2018.1447674

    authors: Shi L,Stachon T,Seitz B,Wagenpfeil S,Langenbucher A,Szentmáry N

    更新日期:2018-06-01 00:00:00

  • Glaucoma Progression and its Relationship with Corrected and Uncorrected Intraocular Pressure in Eyes with History of Refractive Corneal Surgery.

    abstract:PURPOSE:To investigate glaucoma progression and its relationship with corrected and uncorrected intraocular pressure (IOP) in patients with a history of refractive corneal surgery (RCS). METHODS:Totally, 56 eyes of 56 primary open-angle glaucoma patients who had a history of RCS were included. Mean keratometry and cen...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2018.1467930

    authors: Kwon J,Sung KR,Jo J,Yang SH

    更新日期:2018-09-01 00:00:00

  • The association between pH level and corneal recovery from induced edema.

    abstract::Corneal acidosis has been shown to reduce corneal hydration control (CHC) as measured by the rate, expressed as the percent recovery per hour (PRPH), at which the thickness of the cornea decreases exponentially after an increased hydration load. Since the effect of pH on corneal function is of scientific interest and ...

    journal_title:Current eye research

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/02713689508999932

    authors: Cohen SR,Polse KA,Brand RJ,Bonanno JA

    更新日期:1995-05-01 00:00:00

  • Matrix metalloproteinases and tissue inhibitors of metalloproteinases of fibrous humans lens capsules with intraocular lenses.

    abstract:PURPOSE:We located immunohistochemically the matrix metalloproteinases (MMP) -1, -2, -3 and -9 and the tissue inhibitors of matrix metalloproteinases (TIMP) -1 and -2 in the fibrous capsule of patients with intraocular lenses (IOLs). METHODS:During vitreoretinal surgery in 10 patients we obtained post-cataract surgery...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.21.6.962.6989

    authors: Kawashima Y,Saika S,Miyamoto T,Yamanaka O,Okada Y,Tanaka S,Ohnishi Y

    更新日期:2000-12-01 00:00:00

  • Postnatal developmental expression of glutamine and related amino acids in the rat retinas.

    abstract:PURPOSE:To evaluate postnatal developmental changes in the amounts of retinal glutamate, glutamine and GABA, and in the distribution of retinal glutamine in the rat. METHODS:Free amino acids were extracted from rat retinas of different postnatal stages, and the concentrations of glutamate, glutamine and GABA were dete...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689609008907

    authors: Ishikawa A,Shiono T,Ishiguro S,Tamai M

    更新日期:1996-06-01 00:00:00

  • Effect of Optical Defocus on the Kinetic Perimetry in Young Myopic Participants.

    abstract:PURPOSE:The prospective study evaluated the effects of optical defocus on kinetic sensitivity using automated kinetic perimetry. MATERIALS AND METHODS:The 17 eyes of 17 healthy young participants were evaluated. All of the participants had myopia (≥ -5.00 D) and mild to no astigmatism (<1.00 D). Automated kinetic peri...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2014.961614

    authors: Hirasawa K,Shoji N

    更新日期:2015-01-01 00:00:00

  • Discrete expression and distribution pattern of TIMP-3 in the human retina and choroid.

    abstract:PURPOSE:Extracellular matrix homeostasis is dependent in part upon a family of matrix metalloproteinases and their specific inhibitors, the tissue inhibitors of metalloproteinases (TIMPs). Recently, gene defects in TIMP-3 have been identified in the affected individuals of several families with Sorsby's fundus dystroph...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.16.2.102.5086

    authors: Vranka JA,Johnson E,Zhu X,Shepardson A,Alexander JP,Bradley JM,Wirtz MK,Weleber RG,Klein ML,Acott TS

    更新日期:1997-02-01 00:00:00

  • Neutralizing antibody to TGFbeta modulates stromal fibrosis but not regression of photoablative effect following PRK.

    abstract:PURPOSE:Previous studies have suggested that corneal fibrosis controlled by a TGFbeta-mediated cytocrine pathway underlies the development of clinical corneal haze and associated regression of photoablative effect following excimer laser PRK. Using a unique blocking antibody, we evaluated the role of TGFbeta in post-PR...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:

    authors: Møller-Pedersen T,Cavanagh HD,Petroll WM,Jester JV

    更新日期:1998-07-01 00:00:00

  • The development of vernier acuity in infants.

    abstract::Vernier and grating acuity were measured in infants up to 6 months of age using a two-alternative forced-choice preferential looking technique. Vernier resolution was measured using a horizontal vernier grating. The grating was presented on half of the screen while the other half contained horizontal lines which were ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688408997233

    authors: Manny RE,Klein SA

    更新日期:1984-03-01 00:00:00

  • Interleukin (IL)-17A Promotes Angiogenesis in an Experimental Corneal Neovascularization Model.

    abstract:PURPOSE:To explore the roles of interleukin (IL)-17A in alkali-induced corneal neovascularization (CRNV). METHODS:Induction of CRNV by alkali injury was performed and compared in recombinant mouse IL-17A protein or anti-mouse IL-17A neutralizing antibody (Ab)-treated mice. The expression of IL-17A, IL-17A receptor (IL...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2016.1196705

    authors: Liu G,Wu H,Lu P,Zhang X

    更新日期:2017-03-01 00:00:00

  • Effect of shaking of corneal endothelial preservation.

    abstract:PURPOSE:To investigate the effect of shaking on corneal endothelial preservation. METHODS:Thirty-six dog corneal buttons were obtained under standard eye bank procedure, after the animals had been sacrificed for cardiovascular experiments in the surgical department. They were equally divided into two groups. In Group ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.16.11.1111.5111

    authors: Wang IJ,Hu FR

    更新日期:1997-11-01 00:00:00

  • Age-dependent effect of UV light in abnormal alpha neoprotein formation in the lens.

    abstract::The aim of this study was to determine whether or not alpha neoprotein formation can occur in the lens in response to a photolytic process. Alpha crystallin from young calf and aged bovine lenses was irradiated for up to 22 hours with UV light. After cortical alpha crystallin had been irradiated, it completely preserv...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688809001882

    authors: Hibino K,Du J,Dillon J,Malinowski K

    更新日期:1988-11-01 00:00:00

  • Detection of locally produced antibodies to herpes viruses in the aqueous of patients with acquired immune deficiency syndrome (AIDS) or acute retinal necrosis syndrome (ARN).

    abstract::Intraocular synthesis of IgG antibodies against HSV (herpes simplex virus), CMV (cytomegalovirus) and VZV (varicella zoster virus) is considered as an indirect proof of uveoretinal infection. Paired serum and aqueous samples obtained from 16 patients with retinitis associated with AIDS, 3 patients with ARN, 8 patients...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713689008999412

    authors: Luyendijk L,vd Horn GJ,Visser OH,Suttorp-Schulten MS,vd Biesen PR,Rothova A,Kijlstra A

    更新日期:1990-01-01 00:00:00

  • Comparison of Higher-Order Aberrations after LASEK between Two Different Laser Platforms for Low-to-Moderate Myopia.

    abstract:PURPOSE:To compare the differences in higher-order aberrations (HOAs) after laser subepithelial keratomileusis (LASEK) between two different laser platforms. METHODS:One hundred and seven eyes of 107 patients were included in this study. Fifty-six eyes underwent LASEK with the Triple-A profile (an ablation profile of ...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1080/02713683.2020.1726404

    authors: Liu L,Li M,Shi YH,Sun LN,Wang F,Zou J

    更新日期:2020-09-01 00:00:00

  • Expression of perineuronal nets, parvalbumin and protein tyrosine phosphatase σ in the rat visual cortex during development and after BFD.

    abstract:UNLABELLED:Abstract Purpose of the Study: Protein tyrosine phosphatase σ (PTPσ) acts as a neuronal receptor for chondroitin sulfate proteoglycans (CSPGs). CSPGs have inhibitory effects on experience-dependent plasticity and usually form lattice-like cell coatings that surround the parvalbumin (PV) interneurons in the v...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2013.803287

    authors: Liu H,Xu H,Yu T,Yao J,Zhao C,Yin ZQ

    更新日期:2013-10-01 00:00:00

  • Histopathological evaluation of anterior lamellar corneal tissue-on/-off storage conditions on DSAEK donor tissue after storage in organ culture.

    abstract:PURPOSE:To compare the quality of corneal endothelium of precut Descemet-stripping automated endothelial keratoplasty (DSAEK) tissue when transported with and without the anterior lamellar corneal tissue (ALCT) when organ-culture corneal storage methods are used. METHODS:After microkeratome-assisted excision of anteri...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713683.2011.648045

    authors: Jhanji V,Pollock GA,Mackey AL,Beltz J,Vajpayee RB

    更新日期:2012-02-01 00:00:00

  • An intrinsic membrane glycoprotein of the lens.

    abstract::A major glycoprotein of relative molecular weight of 130,000 daltons of chick lens cell membranes was identified by Concanavalin-A staining and enriched for by Con A-Sepharose chromatography. Using both Con A binding and immunological analyses with a specific polyclonal antibody, the glycoprotein was detected in chick...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.3109/02713688608995176

    authors: Heslip J,Bagchi M,Zhang S,Alousi S,Maisel H

    更新日期:1986-12-01 00:00:00

  • Biphasic intraocular pressure response to calcitonin gene-related peptide.

    abstract:PURPOSE:To examine the effects of calcitonin gene-related peptide (CGRP) on intraocular pressure (IOP). METHODS:IOP was periodically measured in rabbits treated with intravitreal injection (20 ael) of either: 1) CGRP (10(-4) approximately 10(-7) M) into one eye; 2) CGRP (10(-4) or 10(-6) M) into both eyes 30 min after...

    journal_title:Current eye research

    pub_type: 杂志文章

    doi:10.1076/ceyr.19.5.432.5291

    authors: Taniguchi T,Nakai Y,Karim Z,Gu ZB,Kawase K,Kitazawa Y

    更新日期:1999-11-01 00:00:00