The association between pH level and corneal recovery from induced edema.

abstract：:Purpose: To map the time course of changes in intraocular straylight of the human eye 1 year after initial lens wearing for orthokeratology treatment using the objective double-pass technique. Materials and Methods: A total of 35 subjects (19 males and 16 females) completed the study. The mean age was 11.46 ± 2.33 yea...

journal_title：Current eye research

authors： Liu G,Jin N,Bi H,Du B,Gu T,Zhang B,Wei R

更新日期：2019-01-01 00:00:00

abstract：:The efficiency of protein immobilization to provide a hydrogel surface with a high affinity for corneal epithelial cells was investigated. The cell adhesive proteins collagen and fibronectin, and the cell adhesive oligopeptide RGDS (arginine-glycine-aspartic acid-serine) were successfully covalently immobilized on pol...

journal_title：Current eye research

authors： Kobayashi H,Ikada Y

更新日期：1991-10-01 00:00:00

abstract：PURPOSE:Membrane-associated mucins (MAMs) play important roles in barrier function and tear stability, and their expression on the ocular surface is altered in dry eye disease. Rebamipide is a mucin secretagogue that promotes the production of mucin-like glycoproteins in human corneal epithelial (HCE) cells. However, t...

journal_title：Current eye research

authors： Itoh S,Itoh K,Shinohara H

更新日期：2014-02-01 00:00:00

abstract：PURPOSE:To characterize the pupil light reflex (PLR), electroretinographic (ERG) and tonometric parameters in healthy rat eyes. METHODS:Brown Norway rats were used for experiments. The PLR was evaluated with a computerized pupillometer (n = 27), ERGs were recorded simultaneously from both eyes (n = 27) and IOP was mea...

journal_title：Current eye research

authors： Grozdanic S,Sakaguchi DS,Kwon YH,Kardon RH,Sonea IM

更新日期：2002-08-01 00:00:00

abstract：PURPOSE:To report the presence of hyper-reflective dots in the vitreous cavity using spectral-domain optical coherence tomography (SD-OCT) in patients with acute symptomatic posterior vitreous detachment (PVD) and investigate their association with the presence of retinal tear. METHODS:The medical records of 77 patien...

journal_title：Current eye research

authors： Oh JH,Oh J,Roh HC

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:To investigate whether retinal impairment was affected by age of rats in acute glaucoma model. METHODS:Young adult and aged rats were randomly divided into normal control, 45 mmHg, 60 mmHg and 90 mmHg groups. Intraocular pressures (IOP) of rats were acutely elevated to 45 mmHg, 60 mmHg and 90 mmHg, respectivel...

journal_title：Current eye research

authors： Tan C,Hu T,Peng MC,Liu SL,Tong JB,Ouyang W,Le Y

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:Frequent steroid drops represent a challenge in patient compliance. This study evaluated the safety and efficacy of 5 minute topical dexamethasone sodium phosphate-Visulex (DSP-Visulex) treatment regimen (two applications on the first week then weekly after) compared to daily prednisolone acetate 1% (PA) for no...

journal_title：Current eye research

authors： Papangkorn K,Truett KR,Vitale AT,Jhaveri C,Scales DK,Foster CS,Montieth A,Higuchi JW,Brar B,Higuchi WI

更新日期：2019-02-01 00:00:00

abstract：:The short and long term response of the trabecular meshwork to a phagocytic challenge and the response of the meshwork to different types of foreign particles was studied by injecting one eye of 25 adult cats with a phagocytic agent (zymosan, blood, or latex microspheres) while the fellow eye received a control soluti...

journal_title：Current eye research

authors： Johnson DH,Richardson TM,Epstein DL

更新日期：1989-11-01 00:00:00

abstract：PURPOSE:Basal cell carcinoma (BCC) is a locally invasive skin tumor which can be subdivided into a circumscribed nodular and an invasive fibrosing subtype. There is increasing evidence that macrophages play an important role in interacting between tumor cells and their microenvironment, thereby affecting not only the i...

journal_title：Current eye research

authors： Kaiser U,Loeffler KU,Nadal J,Holz FG,Herwig-Carl MC

更新日期：2018-09-01 00:00:00

abstract：:Using phosphorus-31 nuclear magnetic resonance (P-31 NMR) spectroscopy the rat crystalline lens was evaluated as a potential animal model for the study of lens metabolic processes relevant to the human. The P-31 NMR spectra of intact rat lenses and rat lens PCA extracts provided comparable qualitative and quantitative...

journal_title：Current eye research

authors： Kopp SJ,Greiner JV,Glonek T

更新日期：1981-01-01 00:00:00

abstract：PURPOSE:To determine the effects of a subconjunctival injection of mitomycin-C (MMC) on iridial circulation in rabbits. METHODS:Dutch rabbits anesthetized with pentobarbital received a 0.2-ml subconjunctival injection of 0.4 mg/ml or 0.1 mg/ml MMC; the contralateral eye received 0.2 ml physiological saline. Intraocula...

journal_title：Current eye research

authors： Tomidokoro A,Araie M,Tamaki Y,Muta K

更新日期：1999-08-01 00:00:00

abstract：PURPOSE:To study whether there exists a relationship between retinal nerve fiber layer thickness and oxygen saturation and to identify whether perivascular thickness (pRNFL) or quadrant thickness (qRNFL) has a stronger correlation. METHODS:Patients without any detectable ocular abnormality on complete ophthalmic evalu...

journal_title：Current eye research

authors： Mohan A,Dabir S,Kurian M,Shetty R,Chidambara L,Kumar RS

更新日期：2016-09-01 00:00:00

abstract：:Perturbations in capillary endothelial cell function are early events in the pathogenesis of diabetic retinopathy. We used tritiated thymidine autoradiography to study the turn-over rate of retinal capillary endothelial cells in retinovascular preparations from normal, untreated diabetic and diabetic mice treated with...

journal_title：Current eye research

authors： Cuthbertson RA,Mandel TE

更新日期：1989-07-01 00:00:00

abstract：:Trabecular meshwork cells from an inbred strain of mice (A/J) were established in tissue culture. Within 1 hour of enucleation, tissue containing the cornea and the chamber angle was excised and placed in tissue culture. Two to five days later, three cell types grew from the explants. Two of these cell types, corneal ...

journal_title：Current eye research

authors： Begley CG,Yue BY,Hendricks RL

更新日期：1991-11-01 00:00:00

abstract：PURPOSE:To evaluate the feasibility of retinal vein bypass surgery for induced branch retinal-vein occlusion (BRVO) in the living porcine eye. METHODS:Fifteen minipigs were used in the study. Seven days before vascular surgery, hyaluronidase and plasmin were intravitreally injected for induction of posterior vitreous ...

journal_title：Current eye research

authors： Shen LJ,Chen YQ,Cheng D,Zhang C,Jiang L,Hong M,Kang QY

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To investigate the effects of pyrrolidine dithiocarbamate (PDTC), a nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) inhibitor, on the expression of matrix metalloproteinases (MMP) and MMP-mediated apoptosis in retinal ganglion cells (RGCs) following the transection of the optic nerve (ON) in ...

journal_title：Current eye research

authors： Sun MH,Chen KJ,Tsao YP,Kao LY,Han WH,Lin KK,Pang JH

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:C5a anaphylatoxin is a potent inflammatory mediator that acts on polymorphonuclear cells (PMN) and monocytes via C5a receptors (C5aR). It mediates chemotaxis of both cell types and stimulates cytokine release from the latter. To investigate whether C5a can act on retinal pigment epithelial (RPE) cells, we exami...

journal_title：Current eye research

authors： Fukuoka Y,Medof EM

更新日期：2001-11-01 00:00:00

abstract：PURPOSE:To examine the morphological changes in the meibomian glands of eyes of patients with dry eye disease using the non-contact infrared meibography system and to assess their relationship with meibomian dropout, signs, and tear-film function. METHODS:Subjects included 264 randomly selected patients (528 eyes) suf...

journal_title：Current eye research

authors： Feng Y,Gao Z,Feng K,Qu H,Hong J

更新日期：2014-10-01 00:00:00

abstract：:We examined jun-B gene expression in the rat retina after a focal retinal injury by in situ hybridization. 30 min after producing a penetrating retinal wound, the retina showed the expression of jun-B mRNA intensively in the inner nuclear layer (INL) and relatively sparsely in the ganglion cell layer. The double-label...

journal_title：Current eye research

authors： Ohki K,Yoshida K,Yamakawa A,Harada T,Matsuda H,Imaki J

更新日期：1995-11-01 00:00:00

abstract：:Samples of aqueous humor from rabbits and humans were examined for growth effects on subconfluent monolayer fibroblast cultures from ocular and extraocular tissues. At a concentration of 20% aqueous by medium volume, both homologous and heterologous aqueous stimulated DNA synthesis in fibroblasts from both species. Th...

journal_title：Current eye research

authors： Burke J,Foster S,Herschler J

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:Several previous studies have shown that glycoconjugates of extracellular matrix, cell membrane and nucleus play an important role in the mediation of cell proliferation, migration and differentiation. Lens epithelial cells and lens fiber cells show regional differences with regard to these parameters. If glyco...

journal_title：Current eye research

authors： Denk PO,Breipohl W,Naib-Majani W,Knorr M

更新日期：1997-06-01 00:00:00

abstract：:About 55% of the acyl groups of dog and human vitreous are unsaturated fatty acids. The major components are oleate (18:1, n-9) and arachidonate (20:4, n-6) with moderate amounts of linoleate (18:2, n-6) and docosahexaenoate (22:6, n-3). Palmitate (16:0) and stearate (18:0) are the major saturated fatty acids. There a...

journal_title：Current eye research

authors： Reddy TS,Birkle DL,Packer AJ,Dobard P,Bazan NG

更新日期：1986-06-01 00:00:00

abstract：PURPOSE:Due to a possible link in humans between atherosclerosis, a high-fat diet, and the development of age-related retinal degenerations, we investigated retinal changes with age and diet in high-fat-fed C57BL/6 mice, a mouse model of human atherosclerosis. METHODS:We fed C57BL/6J mice either a normal chow diet or ...

journal_title：Current eye research

authors： Miceli MV,Newsome DA,Tate DJ Jr,Sarphie TG

更新日期：2000-01-01 00:00:00

abstract：:Purpose: To summarize the research status on the function and mechanism of circRNAs in regulating the occurrence of diabetic retinopathy (DR). Methods: We systematically searched PubMed, Embase.com, and ARVO Abstracts website and reviewed relevant studies. Results: Thousands of circRNAs were found to be aberrantly exp...

journal_title：Current eye research

authors： He M,Zhou R,Liu S,Cheng W,Wang W

更新日期：2020-08-30 00:00:00

abstract：:Recent reports from this laboratory indicate that dopamine (DA2) agonists can lower intraocular pressure (IOP) in rabbits, monkeys and rats. This communication suggests that the cat nictitating membrane (CNM) preparation is a useful model for localizing the site(s) and mechanism(s) of action of dopamine (DA2) agonists...

journal_title：Current eye research

authors： Potter DE,Burke JA

更新日期：1984-11-01 00:00:00

abstract：SIGNIFICANCE:Adopting a risk stratification system and appropriate listing of cases reduces the rates of intraoperative complications during phacoemulsification. Such listing would allow both safe surgery and enhance training, by ensuring an appropriately experienced surgeon is available to operate on a case or supervi...

journal_title：Current eye research

authors： Pooprasert P,Hansell J,Young-Zvandasara T,Muhtaseb M

更新日期：2020-07-30 00:00:00

abstract：:Purpose: To evaluate the microvascular density of the peripapillary and parafoveal areas of the eyes with primary angle closure disease (PACD) using optical coherence tomography angiography (OCTA). Materials and methods: An observational study was conducted with 76 PACD patients (29 eyes with primary angle closure sus...

journal_title：Current eye research

authors： Wang X,Chen J,Kong X,Sun X

更新日期：2020-11-26 00:00:00

abstract：PURPOSE:Disulfiram (DSF) exhibits a wide variety of biological activities, including an anti-inflammatory action, on which we focused our attention. The aim of the present study was to investigate the effect of oral DSF on endotoxin-induced uveitis (EIU) in rats. METHODS:We investigated its effect upon cellular infilt...

journal_title：Current eye research

authors： Kanai K,Itoh N,Yoshioka K,Yonezawa T,Ikadai H,Hori Y,Ito Y,Nagai N,Chikazawa S,Hoshi F,Higuchi S

更新日期：2010-10-01 00:00:00

abstract：:Lenses from normal Wistar rats and those from a Wistar strain with X-ray-induced cataract mutation were examined electron microscopically for morphological characterization and acid phosphatase (AcPase) localization. Ocular anlages of 11 through 18 days of gestation were included in the study. A late-separating or per...

journal_title：Current eye research

authors： Anderson JW,Gorthy WC

更新日期：1984-04-01 00:00:00

abstract：PURPOSE:To evaluate the effect of short-term hypobaric hypoxic conditions (STHC) on intraocular pressure (IOP) in healthy subjects. METHODS:The study group was comprised of 30 healthy participants (60 eyes) with a mean age of 24.8 years. IOP was measured with a Tono-Pen XL tonometer at ground level (792 m above sea le...

journal_title：Current eye research

authors： Karadag R,Sen A,Golemez H,Basmak H,Yildirim N,Karadurmus N,Koseoglu E,Akin A

更新日期：2008-10-01 00:00:00