The development of vernier acuity in infants.

abstract：PURPOSE:To evaluate transcorneal penetration of topically applied 0.5% levofloxacin into the aqueous humor in human eyes. METHODS:Twenty cataract patients (14 females, 6 males) received 3 drops of 0.5% levofloxacin at 15 min intervals from 90 minutes before the surgery. At the beginning of the cataract surgery, 50 mic...

journal_title：Current eye research

authors： Yamada M,Mochizuki H,Yamada K,Kawai M,Mashima Y

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:The pneumococcal capsule is required for pathogenesis in systemic infections, yet reports show most conjunctivitis outbreaks are caused by nonencapsulated pneumococci, while keratitis infections are caused by encapsulated strains. This study aims to determine the effect of capsule in pneumococcal keratitis and ...

journal_title：Current eye research

authors： Norcross EW,Tullos NA,Taylor SD,Sanders ME,Marquart ME

更新日期：2010-09-01 00:00:00

abstract：:Purpose: To summarize the research status on the function and mechanism of circRNAs in regulating the occurrence of diabetic retinopathy (DR). Methods: We systematically searched PubMed, Embase.com, and ARVO Abstracts website and reviewed relevant studies. Results: Thousands of circRNAs were found to be aberrantly exp...

journal_title：Current eye research

authors： He M,Zhou R,Liu S,Cheng W,Wang W

更新日期：2020-08-30 00:00:00

abstract：PURPOSE:To determine by immunohistochemistry the distribution of different nitric oxide synthases (NOS) isoforms in the porcine eye. METHODS:By light microscopy (immunofluorescence), porcine ocular tissues were investigated using monoclonal antibodies against neuronal NOS (nNOS; NOS I), endothelial NOS (ecNOS; NOS III...

journal_title：Current eye research

authors： Meyer P,Champion C,Schlötzer-Schrehardt U,Flammer J,Haefliger IO

更新日期：1999-05-01 00:00:00

abstract：PURPOSE:We compared the hand-guided Moria Carriazo-Barraquer (CBm) microkeratome with the fully automatic SLc microkeratome for Descemet's stripping automated endothelial keratoplasty (DSAEK)-lamella preparation and storage, vis-à-vis accuracy, endothelial cell loss (ECL), and lamellar surface roughness (LSR). METHODS...

journal_title：Current eye research

authors： Fuest M,Salla S,Walter P,Plange N,Kuerten D,Flammersfeld A,Hermel M

更新日期：2016-01-01 00:00:00

abstract：:A prototype automated flicker perimeter was used to investigate flicker luminance thresholds in glaucoma patients (n = 11), ocular hypertensives (high risk n = 10, low and intermediate risk n = 21) and normal controls (n = 10). Differential light sensitivity was measured for one eye of each subject using a flickering ...

journal_title：Current eye research

authors： Austin MW,O'Brien CJ,Wishart PK

更新日期：1994-10-01 00:00:00

abstract：PURPOSE:To generate toxicology profiles of individual drugs on human corneal epithelial cells (HCEC) and compare their in vitro cytotoxicity. METHODS:Monolayer cultures of HCEC were harvested from two human donor eyes. Sunitinib (0.3-10 µg/mL) and Sorafenib (0.3-100 µg/mL), diluted in culture medium (CnT-BM.1, CELLnTE...

journal_title：Current eye research

authors： Bayyoud T,Hofmann J,Spitzer M,Bartz-Schmidt KU,Yoeruek E

更新日期：2014-02-01 00:00:00

abstract：:Importance: To analyze the characteristics and risk factors for pupillary capture (PC) of the intraocular lens (IOL) in congenital ectopia lentis (CEL) patients.Methods: Data of CEL patients who underwent lens extraction and intraocular implantation from 2013 to 2016 at Zhongshan Ophthalmic Center in China were collec...

journal_title：Current eye research

authors： Jin G,Lin J,Xiao B,Chen A,Young CA,Zheng D

更新日期：2020-04-01 00:00:00

abstract：:Cultured retinal glial cells from the rat are responsive to modulation by vasoactive intestinal peptide (VIP). VIP (1 X 10(-6) M) elevated the intracellular cyclic AMP concentration from the basal level of (4.4-11.1) p mole/mg protein to (354-440) p mole/mg protein in three minutes at 25 degrees C. The half-maximal co...

journal_title：Current eye research

authors： Koh SW,Roberge FG

更新日期：1989-11-01 00:00:00

abstract：:High pressure liquid chromatography was used to measure alpha-tocopherol in the retinas of rats reared in a cyclic light or dark environment. These measurements were performed on extracts of whole retinas during the developmental period, 18-60 days, and on isolated ROS from adult animals. Similar alpha-tocopherol dete...

journal_title：Current eye research

authors： Hunt DF,Organisciak DT,Wang HM,Wu RL

更新日期：1984-11-01 00:00:00

abstract：PURPOSE/AIMS:To evaluate the prognostic factors for the best corrected visual acuity (BCVA) and central subfield macular thickness (CSMT) after vitrectomy with internal limiting membrane (ILM) peeling for diabetic macular edema. MATERIALS AND METHODS:A total of 44 eyes of 35 patients who had undergone vitrectomy with ...

journal_title：Current eye research

authors： Yamada Y,Suzuma K,Ryu M,Tsuiki E,Fujikawa A,Kitaoka T

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:Compare the efficacy of treatment of pneumococcal keratitis with cholesterol, moxifloxacin, or a mixture of the two (moxifloxacin/cholesterol). MATERIALS AND METHODS:New Zealand white rabbits were injected intrastromally with 10(6) colony-forming units (CFU) of a clinical keratitis strain of Streptococcus pneu...

journal_title：Current eye research

authors： Sanders ME,Tullos NA,Taylor SD,Norcross EW,King LB,Tolo I,Marquart ME

更新日期：2010-12-01 00:00:00

abstract：PURPOSE:Diabetic maculopathy (DM) treated with photocoagulation may subsequently progress to proliferative diabetic retinopathy (PDR). However, there is insufficient knowledge about the incidence and risk factors for the development of PDR in patients previously treated for DM. MATERIALS AND METHODS:Survival data was ...

journal_title：Current eye research

authors： Bek T

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To determine the effect of prolonged exposure to high glucose on cellular behavior of normal human corneal epithelial cells (HCEC). METHODS:HCEC were cultured in medium under normal or high glucose conditions for 14 days. Proliferation was evaluated by direct cell counting and [(3)H]thymidine incorporation. Ce...

journal_title：Current eye research

authors： Fujita H,Morita I,Takase H,Ohno-Matsui K,Mochizuki M

更新日期：2003-10-01 00:00:00

abstract：:Corneas and tendons dissected from 17-day-old chick embryos were labeled with [35S]methionine in the presence of 0.3 mM alpha,alpha'-dipyridyl. The unhydroxylated, 35S-labeled pro alpha chains and alpha chains were isolated by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. The pro alpha and alpha chains...

journal_title：Current eye research

authors： Kao WW

更新日期：1985-02-01 00:00:00

abstract：:Purpose: To evaluate the microvascular density of the peripapillary and parafoveal areas of the eyes with primary angle closure disease (PACD) using optical coherence tomography angiography (OCTA). Materials and methods: An observational study was conducted with 76 PACD patients (29 eyes with primary angle closure sus...

journal_title：Current eye research

authors： Wang X,Chen J,Kong X,Sun X

更新日期：2020-11-26 00:00:00

abstract：PURPOSE:To investigate epithelial cell adhesion and proliferation on a newly developed elastin-like polymer (ELP) that mimics the functional characteristics of extracellular matrices. MATERIALS AND METHODS:A genetically engineered ELP with cell attachment sequences was adsorbed onto glass coverslips as 1, 2, or 3 mole...

journal_title：Current eye research

authors： Martínez-Osorio H,Juárez-Campo M,Diebold Y,Girotti A,Alonso M,Arias FJ,Rodríguez-Cabello JC,García-Vázquez C,Calonge M

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to characterize swelling pressure-thickness, swelling pressure-hydration and hydration-thickness relations of porcine cornea. METHODS:Mechanical compression tests and free swelling experiments were performed on porcine cornea. A rheometer (DHR-2, TA Instruments) with a thermally contr...

journal_title：Current eye research

authors： Hatami-Marbini H,Etebu E,Rahimi A

更新日期：2013-11-01 00:00:00

abstract：:The goal of this study was to determine the effect of extracellular matrix components on the phagocytic function of the retinal pigment epithelial (RPE) cell. Cultured human fetal RPE cells were established in culture and plated on three commercially-prepared substrates: collagen IV, fibronectin and laminin and on thr...

journal_title：Current eye research

authors： Miceli MV,Newsome DA

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:In the mature retina retinoic acid (RA) biosynthesis was reported to be regulated by light. RA is of vital importance for proper function of the retina. RA activity is mediated by interaction with nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs). The purpose of this study was to determine ...

journal_title：Current eye research

authors： Janssen JJ,Kuhlmann ED,van Vugt AH,Winkens HJ,Janssen BP,Deutman AF,Driessen CA

更新日期：1999-10-01 00:00:00

abstract：:The pigmented epithelium of the vertebrate retina phagocytizes the discarded tips of photoreceptors and it is likely that a specific cellular recognition process is involved in this phenomenon. The apical surface of retinal pigmented epithelium (RPE) contains microvilli which interdigitate with the outer segment regio...

journal_title：Current eye research

authors： Cooper NG,Tarnowski BI,McLaughlin BJ

更新日期：1987-08-01 00:00:00

abstract：PURPOSE:The similar and overlapping activity of VEGF and the potent corneal-derived angiogenic eicosanoid 12(R)-HETrE calls for a study of the temporal relationship in the expression of these two autocoids. Since recent evidence suggests that hypoxia induces the expression of a CYP4B1 mRNA which might be involved in th...

journal_title：Current eye research

authors： Mastyugin V,Mosaed S,Bonazzi A,Dunn MW,Schwartzman ML

更新日期：2001-07-01 00:00:00

abstract：:3-aminotriazole (3AT) is known to reduce catalase levels in ocular tissues when given intravenously or orally. Rabbits were given either 4 ml/kg of a 3M solution of 3AT intravenously or a 2% solution as drinking fluid. Intravenous 3AT administration was followed at 4 hrs by an intracameral injection of hydrogen peroxi...

journal_title：Current eye research

authors： Birnbaum D,Csukas S,Costarides A,Forbes E,Green K

更新日期：1987-12-01 00:00:00

abstract：:Experiments were conducted to test the influence of thapsigargin on the NaK-ATPase activity of cultured cells (ODM2) derived from human nonpigmented ciliary epithelium. The rate of ouabain-sensitive ATP hydrolysis (Na,K-ATPase activity) was diminished in cells that had been pretreated with thapsigargin then permeabili...

journal_title：Current eye research

authors： Mito T,Kuwahara S,Delamere NA

更新日期：1995-08-01 00:00:00

abstract：PURPOSE:Statins have been shown to reduce ocular inflammation in animal models of uveitis and to prevent development of uveitis in observational studies. There have been no experimental human studies evaluating statins' efficacy and safety in uveitis. In this study, we aimed to investigate efficacy and safety of simvas...

journal_title：Current eye research

authors： Shirinsky IV,Biryukova AA,Shirinsky VS

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:Transforming growth factor -beta2 (TGF-beta2) is a predominant isoform of TGF-betas in the eye and plasmin is a peptidase with many functions. To better understand the pathogenesis of retinal microcirculation disorders, the effects of TGF-beta2 and plasmin on cultured bovine retinal pericytes were investigated....

journal_title：Current eye research

authors： Katsura MK,Mishima HK,Minamoto A,Ishibashi F,Yamashita H

更新日期：2000-03-01 00:00:00

abstract：:Macrophages are invariably present in the intraocular membranes of patients with traumatic proliferative vitreoretinopathy (PVR). There are two sources from which these macrophages could be recruited: adjacent tissues and the systemic circulation. In the study described herein, the role of circulating white blood cell...

journal_title：Current eye research

authors： Gabrielian K,Wang HM,Lee M,Ogden TE,Ryan SJ

更新日期：1994-01-01 00:00:00

abstract：:The corneal endothelium of alloxan diabetic dogs was examined by wide-field specular microscopy and compared to that of age-matched non-diabetic dogs. Computer-assisted morphometry of individual cells showed that the diabetic dog endothelium had marked polymegethism and pleomorphism similar to that previously describe...

journal_title：Current eye research

authors： Yee RW,Matsuda M,Kern TS,Engerman RL,Edelhauser HF

更新日期：1985-07-01 00:00:00

abstract：PURPOSE:After corneal injury, persistent epithelial defects (PED's) may occur due to the chronic failure of the regenerating epithelium to adhere to the underlying stroma. The aim of this study was to examine the potential of epsilonaminocaproic acid (EACA) as a topical treatment for PED's. EACA inhibits the activation...

journal_title：Current eye research

authors： Williams PB,Crouch ER Jr,Crouch ER,Mazaheri M

更新日期：1999-02-01 00:00:00

abstract：PURPOSE:To evaluate serum and aqueous humor levels of fetuin-A in patients with pseudoexfoliation syndrome (PEXS) in comparison with those of age- and sex-matched healthy subjects. MATERIALS AND METHODS:This prospective study included 25 patients with PEXS and 25 control subjects who were undergoing cataract surgery w...

journal_title：Current eye research

authors： Yuksel N,Takmaz T,Ozel Turkcu U,Ergin M,Altinkaynak H,Bilgihan A

更新日期：2017-10-01 00:00:00