Abstract：
UNLABELLED:Bulimia nervosa (BN) is a common and disabling psychiatric disorder, which affects mainly young females. The basic therapeutic modalities include pharmacotherapy with selective serotonin reuptake inhibitors, cognitive behavioural therapy and combined treatment. AIM:This 12-week open label study was performed to assess the efficacy of buspirone-5-HT1A receptor agonist in the treatment of bulimia, and to compare it with the efficacy of fluoxetine --the standard treatment of BN. METHOD:We recruited 57 patients, who were assigned to two treatment groups-fluoxetine (n=35) and buspirone (n=22) At baseline, and after treatment we assessed the serotonin level in serum. RESULTS:At least 50% reduction in severity of bulimic symptoms was observed in 15/35 (42.9%) patients treated with fluoxetine and in 11/22 (50.0%) patients receiving buspirone. Depressive symptoms (Beck Depression Inventory) decreased significantly in both treatment groups (from 22.8 to 9.6 points in fluoxetine group and from 19.8 to 10.0 in buspirone group; difference between groups- not significant). Side effects, such as headaches and nausea occurred in both groups rarely and did not cause withdrawal from treatment. Statistical trend towards increased serotonin level in serum was observed after treatment with fluoxetine, and was not associated with buspirone administration. CONCLUSION:Buspirone may have similar efficacy as fluoxetine in reducing bulimic and depressive symptoms in patients with bulimia, however may not cause significant changes of serotonin level in serum.
journal_name
Psychiatr Poljournal_title
Psychiatria polskaauthors
Rajewski A,Rybakowski Fsubject
Has Abstractpub_date
2006-01-01 00:00:00pages
75-82issue
1eissn
0033-2674issn
2391-5854journal_volume
40pub_type
杂志文章,随机对照试验abstract：:On the basis of analyzed clinical material several observations were attempted which were related to the patients' awareness of one's own affective psychosis. It was discovered that patients with endogenous depression considered themselves to be ill, but only in relation to depression. They usually do not perceive in ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
abstract：:Social reactions for mental diseases are very complex, because contacts between healthy people and the ill ones are limited in our society. People are afraid of all symptoms of mental disability and they think that such people should be isolated in closed institutions. The majority of examined people (79%) think that ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVES:The objective of the study was to show the correlation between the feelings of stigmatization and depressive symptoms in psoriasis patients. The study has considered severity of feelings of stigmatization and depressive symptoms, as well as factors such as gender and skin lesions visibility. METHODS:The stu...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/68848
更新日期：2017-12-30 00:00:00
abstract：OBJECTIVES:The aim of the study was to prepare the Polish adaptation of the Young Schema Questionnaire S3-PL. The scale is a self-assessment tool designed to measure 18 early maladaptive schemas. METHODS:The sample consists of 1,529 adults (927 women and 585 men), aged 18-85 years (mean age was 32 years), from non-cli...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/OnlineFirst/76541
更新日期：2018-08-24 00:00:00
abstract：OBJECTIVES:The DEX-S Questionnaire is a tool often used in the self-report of executive difficulties. Numerous data demonstrate that the result of the DEX-S do not differentiate between healthy and clinical groups or people with different characteristics of brain pathology. Limited research taking into account laterali...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/OnlineFirst/85936
更新日期：2019-02-28 00:00:00
abstract：OBJECTIVES:The aim of paper was to explore the attitudes of Polish psychology students towards lesbian mothers whose children undergo psychological intervention, in an imaginary situation of providing professional support to the child. The authors found 3 types of psychologist behaviour: contact omission (withdrawal fr...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2014-07-01 00:00:00
abstract：:It is impossible to think about psychotherapy without reference to the cultural context. In order to understand the development of this domain it is helpful to apply the concept of cultural discourse. When we think about the over one hundred years' history of psychotherapy it becomes clear that understanding of a pers...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-09-01 00:00:00
abstract：OBJECTIVES:Psychometric evaluation of reliability and usefulness of the Polish version of the CESD-R - a revised version of the CES-D - screening test for depression. METHODS:In an online survey the CESD-R and the Beck Depression Inventory were applied to 260 participants (men and women). Reliability was assessed with...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/61614
更新日期：2016-12-23 00:00:00
abstract：:Deep brain stimulation (DBS) is a treatment method that is currently getting more and more attention from psychiatrists. It has proven to be efficacious and safe in the treatment of neurological disorders, mainly Parkinson's disease (PD), dystonia and essential tremor. DBS has very often contributed to successful trea...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/OnlineFirst/103090
更新日期：2019-08-31 00:00:00
abstract：:Caregiver burden was evaluated among family members of 90 schizophrenic patients from hospital psychiatric ward, day hospital or from community psychiatry unit. Psychopathology was evaluated with the use of PANSS while family burden with the use of Tessler's scale which allowed to differentiate between objective and s...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
abstract：:Anorexia nervosa constitutes amajor challenge to medical practitioners, especially clinicians, due to a high rate of chronicity and a very serious risk of relapse. One of the underlying causes of this state of affairs is the ego-syntonicity of the disorder, which differentiates it from similar conditions, and which is...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/OnlineFirst/118601
更新日期：2020-08-31 00:00:00
abstract：:In the review article, the results of studies on regional cerebral blood flow (rCBF) in major depression are presented. Most studies have reported global and regional deficits in cerebral blood flow in major depression as compared to healthy controls. Longitudinal studies show that after recovery from depression an in...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：1999-07-01 00:00:00
abstract：:Brain diseases are one of the most socially and economically burdening diseases in Europe. Among all brain diseases, more than 60% of social and economic costs are generated by mental disorders (mainly depressive disorders and anxiety disorders). Recurrent depressive disorders have been a significant civilizational pr...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/76863
更新日期：2018-06-30 00:00:00
abstract：:The authors discuss the concept of systemic diagnosis and its logical and scientific validity. A diagnosis is the result of the "diagnostic process", with the presence of the acting object (the person making the diagnosis) and the subject (the individual or group patient, such as family), between whom there is a skew ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
abstract：:It was proposed that the repetitive rapid-rate transcranial magnetic stimulation (TMS) induces the functional and structural changes analogous to those which are evoked during the electroconvulsive treatment. Presently, we compared the effects of 8 daily treatments with TMS (t = 5 min, B = 0.1 T, trise = 200 microseco...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:The theme of the article is a 68-year old patient whose case was diagnosed as organic brain disease complicated by musical hallucinosis. The patient was admitted to a mental hospital, several times, as suffering from psychic disturbances of the auditory hallucinosis type whose dominant symptom are musical hallucinatio...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:Premorbid adjustment of 100 hospitalized adolescent patients and its correlation with some clinical variables was assessed and compared with a group of 100 healthy adolescents. The hospitalized group of patients was divided into four diagnostic subgroups according to the diagnostic criteria of ICD 9: psychoses, neuros...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：AIM:The aim of our work was to assess qualitatively and quantatively emotional deficits in patients diagnosed with schizophrenia following ICD-10 criteria in early and late stages of the schizophrenic process and the evaluation of the relationship between genes polymorphism of enzymes influencing dopaminergic, serotoni...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
abstract：:Ketamine is a rapid-acting anaesthetic agent which has been used for over 40 years. It is an antagonist of N-methyl-D-aspartate (NMDA) receptors and agonist of mu and sigma opiate receptors. Ketamine acts through inhibition of sensory parts in the brain and stimulation of the limbic system and optic thalamus. The most...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
abstract：:The aim of the article was to review the hypotheses of schizophrenia in the light of the evolutionary theory. The authors distinguished adaptationist and non-adaptationist hypotheses concerning the evolutionary underpinnings of schizophrenia. The adaptationist hypotheses are firmly based on notions of adaptation, natu...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2003-07-01 00:00:00
abstract：:Anorexia nervosa (AN) most often has its onset in adolescence, which is a crucial period to achieve peak bone mass. The hormonal abnormalities (hypoestrogenism, hypercortisolism, decreased secretion of dehydroepiandrosterone, testosterone, insulin-like growth factor) and malnutrition are associated with profound bone ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/59289
更新日期：2016-01-01 00:00:00
abstract：:A group of 107 patients with diagnosis of syndromological dilusional psychosis underwent a catamnestic examination after 11.2 years from contracting the disease (8.7 years after the first hospitalization). During the first hospitalization with application of different criteria, the dependence of the early (clinical im...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVES:The aim of the study was identification of the barriers making it notably more challenging to access clinics in urban and rural communities. METHODS:The method, which was used in this study adopts the qualitative research perspective. The research tool was an interview with a standardized list of desired in...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：10.12740/PP/60345
更新日期：2017-02-26 00:00:00
abstract：:Cognitive dysfunctions are part of the symptomatology of depressive disorders but they may persist even after the patient reaches symptomatic remission. As persistent symptoms of depression, cognitive dysfunctions may inhibit and restrict the patient's functioning in many spheres and significantly impair its quality. ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：10.12740/PP/OnlineFirst/105415
更新日期：2020-06-30 00:00:00
abstract：:The purpose of this investigation was to analyze several personality dimensions including several psychopathological symptoms of women experiencing infertility. 70 females experiencing infertility and 50 healthy women were examined using psychological methods: MMPI and the State-Trait Anxiety Inventory by Spielberger,...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1995-07-01 00:00:00
abstract：:The cloze procedure was used to examine: predictability in speech samples from schizophrenics and their mothers as well as their ability to gain from the redundancy of language. Schizophrenic patients were found to be less predictable than normals, both schizophrenics and their mothers were less able to make use of th...
journal_title：Psychiatria polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：:Mild cognitive impairment (MCI) is present in on average one-fourth of Parkinson's disease (PD) patients with no dementia diagnosis. Only recently has PD-MCI been treated as a new diagnostic entity. In 2012, unified criteria were adopted which allow both diagnosing MCI in Parkinson's disease (PD-MCI) and further class...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：UNLABELLED:Transsexualism is one of the gender identity disorders where psychological sex is opposed to anatomical sex. This disorder leads to a discrepancy between the preferred social gender and the biological sex. AIM:The aim of this research is to compare knowledge and attitude toward transsexualism in student's o...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:This article discusses biochemical changes of ethyl alcohol in human organism, concentrating especially on the negative influence on the metabolism of liver. The authors describe the process of oxidation of alcohol with alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) and emphasize the role of ADH i ALDH ...
journal_title：Psychiatria polska
pub_type： 杂志文章,评审
doi：
更新日期：2000-05-01 00:00:00
abstract：:In recent years disturbances in releasing neurotrophic growth factors have been viewed as one of the causes of the development of Alzheimer's disease. It is assumed that abnormalities concerning neurotrophic growth factors (e.g. disturbances in releasing them and (or a wrong response of nerve cells to released growth ...
journal_title：Psychiatria polska
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
