Persistent infection of a rat nephroma cell line with kilham rat virus.


:A rat nephroma cell line was found to be a carrier culture of the Kilham rat virus. Infectious virus was demonstrable only by passage of culture materials into other host systems.


J Virol


Journal of virology


Wozniak J,Hetrick F




Has Abstract


1969-09-01 00:00:00












  • Infectivity of a pseudorabies virus mutant lacking attachment glycoproteins C and D.

    abstract::Initiation of herpesvirus infection requires attachment of virions to the host cell followed by fusion of virion envelope and cellular cytoplasmic membrane during penetration. In several alphaherpesviruses, glycoprotein C (gC) is the primary attachment protein, interacting with cell-surface heparan sulfate proteoglyca...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Karger A,Schmidt J,Mettenleiter TC

    更新日期:1998-09-01 00:00:00

  • RNA 5'-triphosphatase, nucleoside triphosphatase, and guanylyltransferase activities of baculovirus LEF-4 protein.

    abstract::Autographa californica nuclear polyhedrosis virus late and very late mRNAs are transcribed by an RNA polymerase consisting of four virus-encoded polypeptides: LEF-8, LEF-9, LEF-4, and p47. The 464-amino-acid LEF-4 subunit contains the signature motifs of GTP:RNA guanylyltransferases (capping enzymes). Here, we show th...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Gross CH,Shuman S

    更新日期:1998-12-01 00:00:00

  • Measles virus ribonucleic acid and protein synthesis: effects of 6-azauridine and cycloheximide on viral replication.

    abstract::Cycloheximide and 6-azauridine were employed to study the time course of measles virus protein and nucleic acid syntheses in AV3 cells. Synthesis of ribonucleic acid (RNA) essential for infectivity was first detected at 6 hr and increased concurrently with the formation of essential protein. Maximum levels of virus-sp...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Portner A,Bussell RH

    更新日期:1973-01-01 00:00:00

  • Control of corynebacteriophage reproduction by heteroimmune repression.

    abstract::Corynebacteriophages beta and gamma are closely related but heteroimmune; hence, gamma reproduces in C7(beta). A series of gamma mutants, designated gamma-bin (beta-inhibited), has been isolated. They reproduce in only 2 to 14% of infected C7(beta) cells, and, as a result, plaque with an efficiency of 10(-4) to 10(-5)...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Groman N,Rabin M

    更新日期:1978-10-01 00:00:00

  • A bulged region of the hepatitis B virus RNA encapsidation signal contains the replication origin for discontinuous first-strand DNA synthesis.

    abstract::Human hepatitis B virus (HBV) is a small DNA virus that replicates inside the viral nucleocapsid by reverse transcription of an RNA intermediate. Encapsidation of this RNA pregenome is mediated by the interaction of the viral replication enzyme P with the structured 5'-proximal RNA element epsilon; replication was tho...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Nassal M,Rieger A

    更新日期:1996-05-01 00:00:00

  • Type I interferon production during herpes simplex virus infection is controlled by cell-type-specific viral recognition through Toll-like receptor 9, the mitochondrial antiviral signaling protein pathway, and novel recognition systems.

    abstract::Recognition of viruses by germ line-encoded pattern recognition receptors of the innate immune system is essential for rapid production of type I interferon (IFN) and early antiviral defense. We investigated the mechanisms of viral recognition governing production of type I IFN during herpes simplex virus (HSV) infect...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Rasmussen SB,Sørensen LN,Malmgaard L,Ank N,Baines JD,Chen ZJ,Paludan SR

    更新日期:2007-12-01 00:00:00

  • Characterization of a YAC-1 mouse cell receptor for group B coxsackieviruses.

    abstract::A receptor on YAC-1 cells, a mouse T-lymphoma cell line, bound all six serotypes of the group B coxsackieviruses (CVB). In addition, the cells produced infectious virus. Each of the CVB competed for the same receptor on YAC-1 cells. CVB3 bound relatively slowly to YAC-1 cells (k = 4 x 10(-11) min-1 cell-1), and there ...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Hsu KH,Crowell RL

    更新日期:1989-07-01 00:00:00

  • Life cycle of an endogenous retrovirus, ZAM, in Drosophila melanogaster.

    abstract::ZAM is an env-containing member of the gypsy family of retrotransposons that represents a possible retrovirus of invertebrates. In this paper, we traced ZAM mobilization to get information about a potential path a retroelement may take to reach the germ line of its host. In situ hybridization on whole-mount tissues an...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Leblanc P,Desset S,Giorgi F,Taddei AR,Fausto AM,Mazzini M,Dastugue B,Vaury C

    更新日期:2000-11-01 00:00:00

  • Physical mapping of adeno-associated virus serotype 4 DNA.

    abstract::The organization of adeno-associated virus serotype 4 (AAV 4) DNA was probed by using restriction enzymes. The cleavage sites of the following enzymes were mapped: BglII, BamI, HincII, KpnI, PstI, SalI, SstI, and XhoI. The orientation of transcription on the physical cleavage map was determined by locating the fragmen...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Muster CJ,Lee YS,Newbold JE,Leis J

    更新日期:1980-09-01 00:00:00

  • Interleukin-1 inhibits hepatitis C virus subgenomic RNA replication by activation of extracellular regulated kinase pathway.

    abstract::Interleukin-1 (IL-1) plays an important role in the inflammatory process. Some studies have demonstrated that IL-1 production was impaired in patients with chronic infections of hepatitis C virus (HCV), implying that IL-1 may play a role in viral clearance. Using an HCV subgenomic replicon cell line, we demonstrate th...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Zhu H,Liu C

    更新日期:2003-05-01 00:00:00

  • Genetic variation of Citrus tristeza virus isolates from California and Spain: evidence for mixed infections and recombination.

    abstract::We examined the population structure and genetic variation of four genomic regions within and between 30 Citrus tristeza virus (CTV) isolates from Spain and California. Our analyses showed that most isolates contained a population of sequence variants, with one being predominant. Four isolates showed two major sequenc...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Rubio L,Ayllón MA,Kong P,Fernández A,Polek M,Guerri J,Moreno P,Falk BW

    更新日期:2001-09-01 00:00:00

  • Mechanism of killing by virus-induced cytotoxic T lymphocytes elicited in vivo.

    abstract::The mechanism of lysis by in vivo-induced cytotoxic T lymphocytes (CTL) was examined with virus-specific CTL from mice infected with lymphocytic choriomeningitis virus (LCMV). LCMV-induced T cells were shown to have greater than 10 times the serine esterase activity of T cells from normal mice, and high levels of seri...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Welsh RM,Nishioka WK,Antia R,Dundon PL

    更新日期:1990-08-01 00:00:00

  • Herpes simplex virus type 1-specific cytotoxic T lymphocytes recognize virus nonstructural proteins.

    abstract::The specificity of herpes simplex virus type 1-specific cytotoxic T cells was examined with target cells expressing either input viral structural antigens or antigens resulting from permissive infection or cells from an interrupted infection in which they expressed predominantly nonstructural immediate-early proteins....

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Martin S,Courtney RJ,Fowler G,Rouse BT

    更新日期:1988-07-01 00:00:00

  • Accelerated heterologous adenovirus prime-boost SIV vaccine in neonatal rhesus monkeys.

    abstract::A pediatric human immunodeficiency virus type 1 (HIV-1) vaccine would be desirable to protect infants against HIV-1 transmission from breast-feeding. Such a vaccine would need to induce protective immunity at mucosal surfaces in neonates as soon as possible after birth. Recombinant adenovirus (rAd) vectors have been s...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Liu J,Li H,Iampietro MJ,Barouch DH

    更新日期:2012-08-01 00:00:00

  • HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis.

    abstract::Vaccine-elicited humoral immune responses comprise an array of antibody forms and specificities, with only a fraction contributing to protective host immunity. Elucidation of antibody effector functions responsible for protective immunity against human immunodeficiency virus type 1 (HIV-1) acquisition is a major goal ...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Wills S,Hwang KK,Liu P,Dennison SM,Tay MZ,Shen X,Pollara J,Lucas JT,Parks R,Rerks-Ngarm S,Pitisuttithum P,Nitayapan S,Kaewkungwal J,Thomas R,Kim JH,Michael NL,Robb ML,McRaven M,Montefiori DC,Hope TJ,Liao HX,Mood

    更新日期:2018-03-14 00:00:00

  • Hepatitis E virus genotype 1 infection of swine kidney cells in vitro is inhibited at multiple levels.

    abstract::Genotype 1 hepatitis E viruses (HEVs) are restricted to primate hosts, whereas genotype 3 HEVs predominantly infect swine, in addition to primates. In order to identify possible determinants of the host range, infectious recombinant viruses and chimeras of a genotype 1 isolate and a genotype 3 isolate were compared fo...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Nguyen HT,Shukla P,Torian U,Faulk K,Emerson SU

    更新日期:2014-01-01 00:00:00

  • Posttranscriptional regulation of beta interferon expression in erythroid Friend cells treated with gamma interferon.

    abstract::Treatment of Friend erythroleukemia cells (FLC) with gamma interferon (IFN-gamma) in the presence of anti-IFN-beta antibodies reduces the effectiveness of the antiviral state and the induction of 2'-5'-oligoadenylate synthetase activity, indicating that the antiviral activity of IFN-gamma in FLC is in part mediated by...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Marziali G,Fiorucci G,Coccia EM,Percario Z,Raber J,Battistini A,Rossi GB,Affabris E,Romeo G

    更新日期:1991-08-01 00:00:00

  • Norovirus proteinase-polymerase and polymerase are both active forms of RNA-dependent RNA polymerase.

    abstract::In vitro mapping studies of the MD145 norovirus (Caliciviridae) ORF1 polyprotein identified two stable cleavage products containing the viral RNA-dependent RNA polymerase (RdRp) domains: ProPol (a precursor comprised of both the proteinase and polymerase) and Pol (the mature polymerase). The goal of this study was to ...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Belliot G,Sosnovtsev SV,Chang KO,Babu V,Uche U,Arnold JJ,Cameron CE,Green KY

    更新日期:2005-02-01 00:00:00

  • Isolation and characterization of measles virus intracellular nucleocapsid RNA.

    abstract::Protocols have been established for the preparation of large amounts of pure measles virus intracellular nucleocapsids. As a result, it has been possible to routinely achieve nucleocapsid RNA yields of approximately 200 micrograms (from approximately 5 X 10(8) infected cells). Electrophoretic analysis of this RNA unde...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Udem SA,Cook KA

    更新日期:1984-01-01 00:00:00

  • Adenovirus infection triggers a rapid, MyD88-regulated transcriptome response critical to acute-phase and adaptive immune responses in vivo.

    abstract::Nearly 50 years ago, the discovery of interferon prompted the notion that host cells innately respond to viral invasion. Since that time, technological advances have allowed this response to be extensively characterized and dissected in vitro. However, these advances have only recently been applied to highly complex, ...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Hartman ZC,Kiang A,Everett RS,Serra D,Yang XY,Clay TM,Amalfitano A

    更新日期:2007-02-01 00:00:00

  • Prion Type-Dependent Deposition of PRNP Allelic Products in Heterozygous Sheep.

    abstract:UNLABELLED:Susceptibility or resistance to prion infection in humans and animals depends on single prion protein (PrP) amino acid substitutions in the host, but the agent's modulating role has not been well investigated. Compared to disease incubation times in wild-type homozygous ARQ/ARQ (where each triplet represents...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Langeveld JP,Jacobs JG,Hunter N,van Keulen LJ,Lantier F,van Zijderveld FG,Bossers A

    更新日期:2015-10-28 00:00:00

  • Genetic location of a mutant of bacteriophage T4 deficient in the ability to induce endonuclease II.

    abstract::Reciprocal three-factor crosses and the use of a partial revertant of a putative ribonucleotide reductase mutant of Escherichia coli B/5 as indicator have made it possible to map denA (deficient in endonuclease II) between nrd-11 (ribonucleotide reductase gene B) and amM69 (gene 63) on the bacteriophage T4 chromosome....

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Ray P,Sinha NK,Warner HR,Snustad DP

    更新日期:1972-01-01 00:00:00

  • Cell-free synthesis and assembly of vesicular stomatitis virus nucleocapsids.

    abstract::The association of newly synthesized vesicular stomatitis virus proteins into nucleocapsid structures was examined in a cell-free system that supports concurrent viral protein synthesis, transcription, and RNA replication. The vesicular stomatitis virus proteins synthesized by this system associated with the newly rep...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Patton JT,Davis NL,Wertz GW

    更新日期:1983-01-01 00:00:00

  • RNA polymerase activity is associated with viral particles isolated from Leishmania braziliensis subsp. guyanensis.

    abstract::Viral particles purified from species of the protozoan parasite Leishmania braziliensis subsp. guyanensis by centrifugation in CsCl gradients were examined for the presence of viral polymerase. We demonstrated that RNA-dependent RNA polymerase is associated with viral particles. Viral transcription was studied in vitr...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Widmer G,Keenan MC,Patterson JL

    更新日期:1990-08-01 00:00:00

  • Antiviral Activity of Myticin C Peptide from Mussel: an Ancient Defense against Herpesviruses.

    abstract:UNLABELLED:Little is known about the antiviral response in mollusks. As in other invertebrates, the interferon signaling pathways have not been identified, and in fact, there is a debate about whether invertebrates possess antiviral immunity similar to that of vertebrates. In marine bivalves, due to their filtering act...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Novoa B,Romero A,Álvarez ÁL,Moreira R,Pereiro P,Costa MM,Dios S,Estepa A,Parra F,Figueras A

    更新日期:2016-08-12 00:00:00

  • Assembly of the coronavirus envelope: homotypic interactions between the M proteins.

    abstract::The viral membrane proteins M and E are the minimal requirements for the budding of coronavirus particles. Since the E protein occurs in particles only in trace amounts, the lateral interactions between the M proteins apparently generate the major driving force for envelope formation. By using coimmunoprecipitation an...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: de Haan CA,Vennema H,Rottier PJ

    更新日期:2000-06-01 00:00:00

  • CD4 T Cells, CD8 T Cells, and Monocytes Coordinate To Prevent Rift Valley Fever Virus Encephalitis.

    abstract::Rift Valley fever virus (RVFV) is an arbovirus that causes disease in livestock and humans in Africa and the Middle East. While human disease is typically mild and self-limiting, some individuals develop severe manifestations, such as hepatitis, hemorrhagic fever, or encephalitis. Encephalitis occurs 2 to 3 weeks afte...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Harmon JR,Spengler JR,Coleman-McCray JD,Nichol ST,Spiropoulou CF,McElroy AK

    更新日期:2018-11-27 00:00:00

  • Nucleosome-like structural subunits of intranuclear parental adenovirus type 2 DNA.

    abstract::The intranuclear structure of parental adenovirus 2 DNA was studied using digestion with micrococcal nuclease as a probe. When cultures were infected with 32P-labeled virions, at a multiplicity of 3,000 particles per cell, 14 to 21% of parental DNA penetrated the cell and reached the nucleus. Of this parental DNA, 60%...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Sergeant A,Tigges MA,Raskas HJ

    更新日期:1979-03-01 00:00:00

  • Temporal effects of gamma interferon deficiency on the course of Friend retrovirus infection in mice.

    abstract::The current studies demonstrate complex and seemingly contradictory effects by gamma interferon (IFN-gamma) on Friend virus (FV) infection. Both temporal and tissue-specific effects were observed. During the first week of infection, IFN-gamma-deficiency caused increased levels of FV infection in multiple tissues. Surp...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Stromnes IM,Dittmer U,Schumacher TN,Schepers K,Messer RJ,Evans LH,Peterson KE,Race B,Hasenkrug KJ

    更新日期:2002-03-01 00:00:00

  • Analysis of the herpes simplex virus genome during in vitro latency in human diploid fibroblasts and rat sensory neurons.

    abstract::We have previously designed in vitro model systems to characterize the herpes simplex virus type 1 (HSV-1) genome during in vitro virus latency. Latency was established by treatment of infected human embryo lung fibroblast (HEL-F) cells or rat fetal neurons with (E)-5-(2-bromovinyl)-2'-deoxyuridine and human leukocyte...

    journal_title:Journal of virology

    pub_type: 杂志文章


    authors: Wigdahl B,Scheck AC,Ziegler RJ,De Clercq E,Rapp F

    更新日期:1984-01-01 00:00:00