Interactions of multilamellar phospholipid vesicles with bovine lymphocytes: effects of alpha-tocopherol on lymphocyte blastogenesis.

abstract：:Structurally diverse dextrans from Leuconostoc mesenteroides and related bacteria have been used extensively in fundamental immunochemical studies such as induction and characterization of anti-dextran antibodies, as well as in studies of their interaction with pneumococcal antisera, normal bovine serum, concanavalin ...

journal_title：Molecular immunology

authors： Jeanes A

更新日期：1986-09-01 00:00:00

abstract：:Proteus sp. and Klebsiella sp. mainly cause infections of the urinary and respiratory tracts or wounds in humans. The representatives of both genera produce virulence factors like lipopolysaccharide (LPS) or outer membrane proteins (OMPs) having much in common in the structures and/or functions. To check how far this ...

journal_title：Molecular immunology

authors： Palusiak A

更新日期：2015-03-01 00:00:00

abstract：:Candida albicans is an opportunistic human-pathogenic fungus, which can cause superficial but also life-threatening invasive infections. The pH-regulated antigen 1 (Pra1) of C. albicans is a surface-associated and secreted protein highly expressed in the hyphal form. Pra1 can bind to complement receptor 3 (CD11b/CD18)...

journal_title：Molecular immunology

authors： Losse J,Svobodová E,Heyken A,Hube B,Zipfel PF,Józsi M

更新日期：2011-09-01 00:00:00

abstract：:Macrophage migration is mediated by complex cellular signaling processes and cytoskeleton re-arrangement. In particular, recent advances indicate that the innate immunity signaling process plays a key role in the regulation of macrophage migration. In this report, we have provided evidence demonstrating the involvemen...

journal_title：Molecular immunology

authors： Gan L,Li L

更新日期：2010-03-01 00:00:00

abstract：:GRX1 (glutaredoxin1), a sulfhydryl disulfide oxidoreductase, is involved in many cellular processes, including anti-oxidation, anti-apoptosis, and regulation of cell differentiation. However, the role of GRX1 in the oxidative stress and apoptosis of osteoarthritis chondrocytes remains unclear, prompting the current st...

journal_title：Molecular immunology

authors： Sun J,Wei X,Lu Y,Cui M,Li F,Lu J,Liu Y,Zhang X

更新日期：2017-10-01 00:00:00

abstract：:Art v 3, the lipid-transfer protein (LTP) of Artemisia vulgaris pollen is a relevant allergen showing frequent cross-reactivity with homologues in other plants. Here we report the identification of four full-length Art v 3 sequences obtained by cDNA cloning using mass spectrometry-based sequencing. Two isoforms, Art v...

journal_title：Molecular immunology

authors： Gadermaier G,Harrer A,Girbl T,Palazzo P,Himly M,Vogel L,Briza P,Mari A,Ferreira F

更新日期：2009-06-01 00:00:00

abstract：:Immunoglobulins (Ig) require correct folding and assembly of both heavy (H) and light (L) chains to form a functional H2L2 dimer that is secreted from plasma cells. This process is dependent upon the endoplasmic reticulum (ER) chaperone BiP, which targets improperly, folded or assembled Ig molecules for degradation. W...

journal_title：Molecular immunology

authors： McLean GR,Torres M,Trotter B,Noseda M,Bryson S,Pai EF,Schrader JW,Casadevall A

更新日期：2005-05-01 00:00:00

abstract：:The effect of fragment B of staphylococcal protein A on the binding of rabbit IgG to human granulocytes has been examined. When rabbit IgG sensitized sheep erythrocytes (EA) were preincubated with increasing amounts of fragment B, a dose dependent inhibition of rosette formation between the human granulocytes and the ...

journal_title：Molecular immunology

authors： Barnett Foster DE,Sjoquist J,Painter RH

更新日期：1982-03-01 00:00:00

abstract：:A new sulfhydryl redox model of antibody-dependent endocytosis is proposed. This model synthesizes many previous studies employing a variety of experimental approaches. Predictions of this model can be tested experimentally. ...

journal_title：Molecular immunology

authors： Petty HR

更新日期：1985-08-01 00:00:00

abstract：:Activation-induced cytidine deaminase (AID) is critical for immunoglobulin (Ig) diversification in B cells. The majority of evidence supports the model that AID modifies Ig genes at the DNA level by deaminating cytosines into uracils. The mutagenic activity is largely restricted to Ig genes to avoid genomic damage in ...

journal_title：Molecular immunology

authors： Kim Y,Tian M

更新日期：2009-10-01 00:00:00

abstract：:The fifth component of the complement cascade, C5a, was iodinated using the Bolton-Hunter reagent. Results from the present study, using the high affinity ligand, [125I]Bolton-Hunter-labeled C5a ([125I]BH-C5a), revealed a single binding site on membranes prepared from human neutrophils, U-937 cells and human monocytes...

journal_title：Molecular immunology

authors： Braunwalder AF,Musmanno D,Galakatos N,Garlick RH,Haston WO,Rediske JJ,Wennogle L,Seligmann B,Sills MA

更新日期：1992-11-01 00:00:00

abstract：:We have recently developed an in vitro culture model enabling the large-scale expansion of switched-memory B lymphocytes, producing a polyclonal human IgG repertoire. Given the importance of glycosylation for the functions of immunoglobulins, we analyzed the N-glycosylation profiles of the immunoglobulin G (IgG) in th...

journal_title：Molecular immunology

authors： Ritamo I,Cloutier M,Valmu L,Néron S,Räbinä J

更新日期：2014-02-01 00:00:00

abstract：:Mammary epithelia and the epidermis share a common embryologic origin. Like resident epidermal T cells (ETC), a significant number of murine mammary gland T cells (MTC) express Vgamma5-T-cell receptors (TCR). MTC were assessed to see if they express the same invariant Vgamma5/Vdelta1-TCRs as those of ETC. MTC-derived ...

journal_title：Molecular immunology

authors： Reardon C,Born WK,O'Brien RL

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DCs) and regulatory T (Treg) cells are crucial for inducing immune tolerance. However, the suppressive function of infused Treg cells and immature DCs (imDCs) following solid organ transplantation remains unclear. METHODS:ImDCs derived from DA-donor rats and Treg cells isolated from spleens...

journal_title：Molecular immunology

authors： He W,Chen L,Zheng L,Luo L,Gao L

更新日期：2016-11-01 00:00:00

abstract：:Cytohesin-1 is a guanine nucleotide exchange factor for ADP ribosylation factor 6 (Arf6) in human blood neutrophils and differentiated PLB-985 neutrophil-like cells. Cytohesin-1 regulates adhesion and the transendothelial migration of monocytes, dendritic cells and T lymphocytes through activation of the β2 integrin L...

journal_title：Molecular immunology

authors： El azreq MA,Bourgoin SG

更新日期：2011-07-01 00:00:00

abstract：:Deficiencies in the classical pathway of complement activation have some common features but show also great differences. Deficiencies of each of the components (C1q, C1s, C1r, C4 and C2) imply increased susceptibility to bacterial infections. They are also associated with increased risk to develop systemic lupus eryt...

journal_title：Molecular immunology

authors： Truedsson L

更新日期：2015-11-01 00:00:00

abstract：:A monoclonal antibody (vpg15) has been described which can block infection with feline immunodeficiency virus (FIV) and which recognizes the feline homologue of CD9. In order to study the role of feline CD9 in infection with FIV we have molecularly cloned a cDNA encoding feline CD9 by R.A.C.E (rapid amplification of c...

journal_title：Molecular immunology

authors： Willett BJ,Neil JC

更新日期：1995-04-01 00:00:00

abstract：:It is well established that aggregation of cell surface immunoglobulin is involved in signal transduction by cells of the immune system. It is less well understood what special properties of these cell surface aggregates are important in initiating the signal cascade. Several authors have proposed that cells respond t...

journal_title：Molecular immunology

authors： Posner RG,Dembo M

更新日期：1994-12-01 00:00:00

abstract：:An important function of Fcγ receptors is the removal of IgG-containing immune complexes from the circulation. The activating receptor FcγRIIA and inhibitory receptor FcγRIIB2 are both expressed on human myeloid cells, and are both capable of mediating endocytosis of immune complexes. We studied endocytosis of these t...

journal_title：Molecular immunology

authors： Zhang CY,Booth JW

更新日期：2011-10-01 00:00:00

abstract：:Individually amplified kappa cDNA molecules from single B lymphocytes revealed sequence heterogeneity and aberrantly spliced products. The nature and frequency of the base changes and their absence from similarly amplified beta2 microglobulin transcripts indicate that they were not derived by Taq polymerase misincorpo...

journal_title：Molecular immunology

authors： Jena PK,Liu AH,Smith DS,Aviszus K,Wysocki LJ

更新日期：2000-04-01 00:00:00

abstract：:Serotonin release from rat basophilic leukemia (RBL) cells, sensitized with a DNP-binding monoclonal IgE, was stimulated with solid surface (polystyrene)-bound DNP-amino acids. The stimulatory potency of DNP-amino acids was dependent on the structure of amino acid attached to DNP. Generally, DNP-amino acids with high ...

journal_title：Molecular immunology

authors： Varga JM,Kalchschmid G,Klein GF,Fritsch P

更新日期：1991-06-01 00:00:00

abstract：:This study analyzes the gene repertoire coding for antibodies to an evolutionary novel immunogenic carbohydrate antigen in mice. The alpha-gal epitope (Gal alpha 1-3Gal beta 1-4GlcNAc-R) is an autoantigen, abundantly expressed in wild type mice, but absent in alpha 1,3galactosyltransferase knock-out (KO) mice, where i...

journal_title：Molecular immunology

authors： Chen ZC,Radic MZ,Galili U

更新日期：2000-06-01 00:00:00

abstract：:Noxiustoxin (NTX) is a short-chain toxin from the venom of the scorpion Centruroides noxius Hoffmann, whose molecular structure and physiological effects have been characterized in detail, whereas the antigenic properties of this and other K(+) channel-blocking toxins are poorly studied. A monoclonal antibody against ...

journal_title：Molecular immunology

authors： Gazarian T,Selisko B,Hérion P,Gazarian K

更新日期：2000-08-01 00:00:00

abstract：:Cardamonin, a chalcone isolated from the fruits of a local plant Alpinia rafflesiana, has demonstrated anti-inflammatory activity in cellular models of inflammation. In this report, we evaluated the ability of cardamonin to suppress both NO and PGE2 synthesis, iNOS and COX-2 expression and enzymatic activity, and key ...

journal_title：Molecular immunology

authors： Israf DA,Khaizurin TA,Syahida A,Lajis NH,Khozirah S

更新日期：2007-02-01 00:00:00

abstract：:In this review we introduce the basic principles of epigenetic gene regulation and discuss them in the context of dendritic cell (DC) development and differentiation. Epigenetic mechanisms control the accessibility of chromatin for DNA binding proteins and thus they control gene expression. These mechanisms comprise c...

journal_title：Molecular immunology

authors： Chauvistré H,Seré K

更新日期：2020-12-01 00:00:00

abstract：:MTX is an effective therapy for autoimmune-inflammatory diseases. The mechanisms that mediate these actions are not completely clear. It is accepted that many of these effects are mediated through the release of adenosine with the activation of the adenosine receptor A2. MTX is used as a steroid sparing agent. An impr...

journal_title：Molecular immunology

authors： Goecke IA,Alvarez C,Henríquez J,Salas K,Molina ML,Ferreira A,Gatica H

更新日期：2007-03-01 00:00:00

abstract：INTRODUCTION:Previous studies have suggested the importance of somatic mutations and arginine, asparagine and lysine residues in the complementarity determining regions (CDRs) of antiphospholipid antibodies (aPL) implicated in the pathogenesis of the antiphospholipid antibody syndrome. The relative contributions of the...

journal_title：Molecular immunology

authors： Giles IP,Haley J,Nagl S,Latchman DS,Chen PP,Chukwuocha RU,Isenberg DA,Rahman A

更新日期：2003-09-01 00:00:00

abstract：:This paper reports the cloning and sequencing of two pro-inflammatory cytokines, interleukin (IL)-1beta and IL-8, in haddock (Melanogrammus aeglefinus) by homology cloning. The complete transcript of the haddock IL-1beta was sequenced and contained 1043 bp, including a 762 bp open reading frame. The 3' end of the gene...

journal_title：Molecular immunology

authors： Corripio-Miyar Y,Bird S,Tsamopoulos K,Secombes CJ

更新日期：2007-02-01 00:00:00

abstract：:Natural killer (NK) cells express receptors that are specific for MHC class I molecules. These receptors play a crucial role in regulating the lytic and cytokine expression capabilities of NK cells. In humans, three distinct families of genes have been defined that encode for receptors of HLA class I molecules. The fi...

journal_title：Molecular immunology

authors： Borrego F,Kabat J,Kim DK,Lieto L,Maasho K,Peña J,Solana R,Coligan JE

更新日期：2002-02-01 00:00:00

abstract：:Human leukocyte antigens (HLA) allele determination is becoming an increasingly important aspect in the field of transplantation as well as in the area of HLA association with a number of diseases. Through Lebanon's history, this country, situated at a crossroads between Europe, Asia and Africa, has been a host for va...

journal_title：Molecular immunology

authors： Samaha H,Rahal EA,Abou-Jaoude M,Younes M,Dacchache J,Hakime N

更新日期：2003-07-01 00:00:00