Interactions of cytokines, S-Adenosylmethionine, and S-Adenosylhomocysteine in alcohol-induced liver disease and immune suppression.

abstract：:Sensitive and specific enzyme-linked immunosorbent assays (ELISA) were developed to detect separately the binding of polymerized human serum albumin (PHSA) to its antibody (A-PHSA) and to the hepatitis B surface antigen (HBsAg). A-PHSA was not detected in normal serum, whereas more than one-third to about half of sera...

journal_title：Journal of gastroenterology and hepatology

authors： Dash S,Panda SK,Nayak NC

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND AIM:Exogenous 8-hydroxydeoxyguanosine (8-OHdG) was suggested as an inhibitor of Rac1 and NADPH oxidase (NOX). The aim of this study was to evaluate the effects of the exogenous 8-OHdG on hepatic fibrogenesis in vitro and in vivo model of liver fibrosis. METHODS:Adult Sprague-Dawley rats were allocated t...

journal_title：Journal of gastroenterology and hepatology

authors： Shin SK,Kim KO,Kim SH,Kwon OS,Choi CS,Jeong SH,Kim YS,Kim JH,Chung MH

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND AIM:This study aimed to estimate the time to precursor progression and to identify significant predicators. METHODS:One hundred thirty-three precursor and 311 normal cases detected in a population-based screening were surveyed for 5.5 years. Precursor progression was defined as worsening of dysplasia or...

journal_title：Journal of gastroenterology and hepatology

authors： Wen D,Zhang L,Wang X,Li Y,Ma C,Liu X,Zhang J,Wen X,Yang Y,Zhang F,Wang S,Shan B

更新日期：2015-12-01 00:00:00

abstract：:The three-dimensional ultrastructure of nuclei and cell organelles including rough-surfaced endoplasmic reticulum (RER), mitochondria, and cytoskeleton were studied in normal rat hepatocytes by the quick-freezing and deep-etching method. Peroxisomes and mitochondria were observed as spherical structures with granular ...

journal_title：Journal of gastroenterology and hepatology

authors： Furuta K,Ohno S,Gibo Y,Kiyosawa K,Furuta S

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:With the prevalence of Helicobacter pylori (H. pylori) infection rapidly decreasing in Japan, endoscopic findings and dyspeptic symptoms need to be re-evaluated. METHODS:In a health check-up program, endoscopy was performed on 530 young Japanese subjects (371 men and 159 women) born in the 1970s. Helicobact...

journal_title：Journal of gastroenterology and hepatology

authors： Shimatani T,Inoue M,Iwamoto K,Hyogo H,Yokozaki M,Saeki T,Tazuma S,Horikawa Y

更新日期：2005-09-01 00:00:00

abstract：:The identification of activated hepatic stellate cells and related cell types as key fibrogenic effectors during liver injury has led to intense evaluation of transcriptional events underlying their behavior. While initial studies focused on characterizing interactions between transcription factors and regulatory regi...

journal_title：Journal of gastroenterology and hepatology

authors： Friedman SL

更新日期：2006-10-01 00:00:00

abstract：:The Korean College of Helicobacter and Upper Gastrointestinal Research first developed guidelines for the diagnosis and treatment of Helicobacter pylori (H. pylori) infection in 1998, and revised guidelines were proposed in 2009 by the same group. Although the revised guidelines were based on a comprehensive review of...

journal_title：Journal of gastroenterology and hepatology

authors： Kim SG,Jung HK,Lee HL,Jang JY,Lee H,Kim CG,Shin WG,Shin ES,Lee YC,Korean College of Helicobacter and Upper Gastrointestinal Research.

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Cancer invasion and metastasis are critical events for patient prognosis; however, the most important step in the whole process of lymph node (LN) metastasis in gastric cancer remains obscure. In this study, the significance of cancer cell behaviors, such as cell detachment, stromal invasion and lym...

journal_title：Journal of gastroenterology and hepatology

authors： Kamata I,Ishikawa Y,Akishima-Fukasawa Y,Ito K,Akasaka Y,Uzuki M,Fujimoto A,Morita H,Tamai S,Maehara T,Ogata K,Shimokawa R,Igarashi Y,Miki K,Ishii T

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis C virus (HCV) and environmental hepatotoxins may have an indirect influence on health by altering the synthesis and function of hormones, particularly reproductive hormones. We aimed to evaluate liver diseases and sex steroid hormones in Egypt, which has the highest prevalence of HCV worldw...

journal_title：Journal of gastroenterology and hepatology

authors： Aguilar CE,Soliman AS,McConnell DS,Zekri AR,Banerjee M,Omar A,Sharawy M,Omar S,Raouf A,Sowers MR

更新日期：2008-07-01 00:00:00

abstract：:There is an increasing burden in digestive cancer in the coming years. With the advancement of endoscopic therapy, new molecular target therapy and minimally invasive ablation therapy, the treatment of digestive cancer will become more complicated. In Asia where gastric cancer and hepatocellular carcinoma are still pr...

journal_title：Journal of gastroenterology and hepatology

authors： Sung J

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:A lack of published data remains on factors associated with the treatment response to proton pump inhibitors (PPI) in patients with non-erosive reflux disease (NERD). METHODS:Studies on effectiveness of PPI in patients with NERD were identified using the MEDLINE database and manual searches of the available...

journal_title：Journal of gastroenterology and hepatology

authors： Hiyama T,Matsuo K,Urabe Y,Fukuhara T,Tanaka S,Yoshihara M,Haruma K,Chayama K

更新日期：2009-08-01 00:00:00

abstract：:A 57 year old Japanese male was incidentally found to have a 7.5 cm diameter hepatic haemangioma. Eleven years later he was operated on because the haemangioma had grown into a 17 cm mass causing upper abdominal fullness. Volumetry on computerized tomograms disclosed that the haemangioma had grown from 123 cm3 to 1343...

journal_title：Journal of gastroenterology and hepatology

authors： Yoshida J,Yamasaki S,Yamamoto J,Kosuge T,Takayama T,Hasegawa H,Takayasu K,Muramatsu Y,Moriyama N,Hirohashi S

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND AND AIMS:To evaluate and compare laparoscopic splenectomy and partial splenic embolization as supportive intervention for cirrhotic patients with hypersplenism to overcome peripheral cytopenia before the initiation of and during interferon therapy or anticancer therapy for hepatocellular carcinoma. METHODS:...

journal_title：Journal of gastroenterology and hepatology

authors： Tomikawa M,Akahoshi T,Sugimachi K,Ikeda Y,Yoshida K,Tanabe Y,Kawanaka H,Takenaka K,Hashizume M,Maehara Y

更新日期：2010-02-01 00:00:00

abstract：:Antipyrine metabolism is widely used as an index of the drug-metabolizing reserve of the liver. It is well known that metabolism of this drug is impaired in subjects with acute hepatitis or cirrhosis, but conflicting data have been reported regarding patients with chronic postinfectious hepatitis or liver cancer. We s...

journal_title：Journal of gastroenterology and hepatology

authors： Grieco A,Castellano R,Matera A,Marcoccia S,Di Rocco P,Ragazzoni E,Vecchio FM,Gasbarrini G

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Outer membrane proteins of Helicobacter pylori mediate important pathogen-host interactions such as colonization, adhesion and the inflammatory response. hopQ genotypes have been suggested to be associated with increased risk of peptic ulcer. The aim of this study was to test the relation of hopQ ge...

journal_title：Journal of gastroenterology and hepatology

authors： Ohno T,Sugimoto M,Nagashima A,Ogiwara H,Vilaichone RK,Mahachai V,Graham DY,Yamaoka Y

更新日期：2009-03-01 00:00:00

abstract：:It was recently reported that mutations in the precore and core promoter region of hepatitis B virus (HBV) are associated with fulminant hepatitis. The aim of this study was to investigate the association of mutations in the precore and core promoter region of HBV with fulminant and severe acute hepatitis. We studied ...

journal_title：Journal of gastroenterology and hepatology

authors： Aritomi T,Yatsuhashi H,Fujino T,Yamasaki K,Inoue O,Koga M,Kato Y,Yano M

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND AIM:Mucosal injury caused by gastroesophageal reflux may result in changes in esophageal mucosal blood flow. Little is known about esophageal mucosal blood flow in patients with gastroesophageal reflux disease (GERD). Here we examined esophageal mucosal blood flow and the effects of treatment in patients...

journal_title：Journal of gastroenterology and hepatology

authors： Mine S,Iida T,Tabata T,Okada Y,Tanaka Y

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND AIM:The vaccination against hepatitis B virus (HBV) is recommended in patients with inflammatory bowel disease (IBD). However, the response to this vaccine seems to be lower in IBD patients than in the general population. This study aims to evaluate the immunogenicity of the HBV vaccine in a cohort of pa...

journal_title：Journal of gastroenterology and hepatology

authors： Cossio-Gil Y,Martínez-Gómez X,Campins-Martí M,Rodrigo-Pendás JÁ,Borruel-Sainz N,Rodríguez-Frías F,Casellas-Jordà F

更新日期：2015-01-01 00:00:00

abstract：:This study examined Na+/H+ ion exchange of caecal and colonic mucus. Two distinct Na+/H+ ion exchange populations of caecal mucus were identified, one group being a cation exchanger and the other an anion exchanger, suggesting that caecal mucus has ampholyte properties responsive to changing physical and chemical prop...

journal_title：Journal of gastroenterology and hepatology

authors： Duncan CE,Tasman-Jones C

更新日期：1992-01-01 00:00:00

abstract：:Prostaglandin E1 (PGE1) has been reported to have, experimentally and clinically, a protective effect against liver damage. This effect may result from the relaxation of hepatic stellate cells, whose contraction induces vasoconstriction of hepatic sinusoids. However, prostaglandins are unstable and a new drug delivery...

journal_title：Journal of gastroenterology and hepatology

authors： Wang XE,Watanabe S,Oide H,Hirose M,Itatsu T,Osada T,Takazakura Y,Yokoi Y,Sato N

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND AND AIM:White opaque substance (WOS) is a novel endoscopic finding in gastric neoplasms, indicating the intracellular accumulation of lipid droplets (LDs). However, gastric lipid metabolism has not been extensively investigated, even in normal mucosa. We investigated the expression profiles of lipid-metaboli...

journal_title：Journal of gastroenterology and hepatology

authors： Enjoji M,Kohjima M,Ohtsu K,Matsunaga K,Murata Y,Nakamuta M,Imamura K,Tanabe H,Iwashita A,Nagahama T,Yao K

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Balloon-occluded retrograde transvenous obliteration (B-RTO) is an effective treatment for gastric varices (GVx), as well as hepatic encephalopathy. The aim of this study was to examine the changes of the hepatic vein pressure gradient (HVPG) after B-RTO and determine the relation between the change...

journal_title：Journal of gastroenterology and hepatology

authors： Uehara H,Akahoshi T,Tomikawa M,Kinjo N,Hashimoto N,Nagao Y,Kamori M,Maehara Y

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND AIM:Application of acetic acid topically to the mucosal or serosal side of the stomach has been well used to create a chronic gastric ulcer model. The aim of the present study was to apply it as a new cytoreductive approach in a mouse model of gastric cancer. METHODS:A total of 43 genetically engineered...

journal_title：Journal of gastroenterology and hepatology

authors： Okabe S,Kodama Y,Cao H,Johannessen H,Zhao CM,Wang TC,Takahashi R,Chen D

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND AIM:The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD. METHODS:The study was designed as a multicenter, randomiz...

journal_title：Journal of gastroenterology and hepatology

authors： Xiao Y,Li Y,Shu J,Li Y,Xu J,Ren J,Liu D,Wang J,Zhou L,Li Y,Tang G,Tian D,Zhang S,Hou X,Wang H,Li Z,Lv N,Chen M

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Biliary disease is one of the most common causes of acute pancreatitis in adults; however, this cause and outcome in children have rarely been described in the literature. Therefore, the present study was conducted to evaluate the role of biliary disease as a cause of acute pancreatitis in children....

journal_title：Journal of gastroenterology and hepatology

authors： Choi BH,Lim YJ,Yoon CH,Kim EA,Park YS,Kim KM

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Indoleamine 2,3-dioxygenase (IDO) is a tryptophan catabolic enzyme. Recent studies have focused on the immunoregulatory role of IDO in mononuclear cells. The role of IDO in hepatocellular carcinoma (HCC) cell lines and HCC patients was examined. METHODS:The expression of IDO mRNA in peripheral blood mononuc...

journal_title：Journal of gastroenterology and hepatology

authors： Ishio T,Goto S,Tahara K,Tone S,Kawano K,Kitano S

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatocellular carcinoma (HCC) is characteristically a hypervascular tumor and its progression is known to be closely related to angiogenesis. In this study, we investigated angiopoietin-2 (Ang-2) and vascular endothelial growth factor (VEGF) levels in the hepatic vein draining from HCC, as well as i...

journal_title：Journal of gastroenterology and hepatology

authors： Kuboki S,Shimizu H,Mitsuhashi N,Kusashio K,Kimura F,Yoshidome H,Ohtsuka M,Kato A,Yoshitomi H,Miyazaki M

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND AIM:Gastric cancer is a major health burden in the Asia-Pacific region but consensus on prevention strategies has been lacking. We aimed to critically evaluate strategies for preventing gastric cancer. METHODS:A multidisciplinary group developed consensus statements using a Delphi approach. Relevant dat...

journal_title：Journal of gastroenterology and hepatology

authors： Fock KM,Talley N,Moayyedi P,Hunt R,Azuma T,Sugano K,Xiao SD,Lam SK,Goh KL,Chiba T,Uemura N,Kim JG,Kim N,Ang TL,Mahachai V,Mitchell H,Rani AA,Liou JM,Vilaichone RK,Sollano J,Asia-Pacific Gastric Cancer Consensus Co

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND AIM:Transforming growth factor-β (TGF-β) has been shown to play a central role in the promotion of cell motility, but its functional mechanism has remained unclear. With the aim of investigating the diagnostic and treatment modalities for patients with hepatocellular carcinoma (HCC), the signaling pathwa...

journal_title：Journal of gastroenterology and hepatology

authors： Sato M,Matsuda Y,Wakai T,Kubota M,Osawa M,Fujimaki S,Sanpei A,Takamura M,Yamagiwa S,Aoyagi Y

更新日期：2013-06-01 00:00:00