Intracellular mechanisms underlying lipid accumulation (white opaque substance) in gastric epithelial neoplasms: A pilot study of expression profiles of lipid-metabolism-associated genes.

abstract：BACKGROUND:The association between body mass index (BMI) and mortality from gastrointestinal (GI) cancer remains unclear, especially in Asian populations. METHODS:A total of 510 148 Korean adults who participated in routine health examinations during the period 2002-2003 were followed up until 2013. RESULTS:During a ...

journal_title：Journal of gastroenterology and hepatology

authors： Jeong SH,Kim P,Yi SW,Kim YJ,Baeg MK,Yi JJ

更新日期：2018-02-06 00:00:00

abstract：BACKGROUND AND AIM:The incidence of colorectal cancer (CC) is increasing in many Asian countries, but decreasing in western countries. The present study examined the local incidence of CC in the past few decades. METHODS:A population based study, using data from Hong Kong (HK) Cancer Registry, was carried out to exami...

journal_title：Journal of gastroenterology and hepatology

authors： Yee YK,Gu Q,Hung I,Tan VP,Chan P,Hsu A,Pang R,Lam CS,Wong BC

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Australia receives many migrants from countries with a high prevalence of hepatitis C infection. General practitioners, who are often the first health professionals consulted, need to be aware of risk factors and complications associated with hepatitis C in this group. METHODS:Four hundred and forty-seven g...

journal_title：Journal of gastroenterology and hepatology

authors： Dev A,Sievert W

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND AND AIM:Entecavir (ETV) induces biochemical and histologic improvement of the liver in patients with chronic hepatitis B. This study aimed to confirm that 2 years of ETV treatment improves liver function and non-invasive fibrosis markers in patients with hepatitis B virus (HBV)-associated cirrhosis. METHODS...

journal_title：Journal of gastroenterology and hepatology

authors： Shin SK,Kim JH,Park H,Kwon OS,Lee HJ,Yeon JE,Byun KS,Suh SJ,Yim HJ,Kim YS,Kim JH

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND AND AIM:Helicobacter pylori (H. pylori) infection is a strong risk factor for the development of gastric cancer. In 2013, the Japanese government approved H. pylori eradication therapy in patients with chronic gastritis as well as peptic ulcer. However, the continuing decline in eradication rates for first-l...

journal_title：Journal of gastroenterology and hepatology

authors： Kawai T,Takahashi S,Suzuki H,Sasaki H,Nagahara A,Asaoka D,Matsuhisa T,Masaoaka T,Nishizawa T,Suzuki M,Ito M,Kurihara N,Omata F,Mizuno S,Torii A,Kawakami K,Ohkusa T,Tokunaga K,Mine T,Sakaki N

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Experimental acute gastric ulcerations (EAGU) are healed very rapidly. This healing process has two steps; mucosal restitution and delayed repair. Adenosine 5'-triphosphate (ATP)-dependent potassium channels (K(ATP)) have a regulatory role in the gastrointestinal physiology. In the present study, th...

journal_title：Journal of gastroenterology and hepatology

authors： Rahgozar M,Pazokitoroudi H,Bakhtiarian A,Djahanguiri B

更新日期：2001-03-01 00:00:00

abstract：:Iatrogenic superior mesenteric arteriovenous fistula is rare. We treated a patient with this problem 6 years after small bowel resection for intestinal obstruction. The symptoms and signs were those of intestinal ischaemia and portal hypertension with an abdominal bruit. Ultrasonography and enhanced computerized tomog...

journal_title：Journal of gastroenterology and hepatology

authors： Iwai M,Kashiwadani M,Suyama Y,Miyoshi M,Kashima K

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND AND AIM:This study investigated whether diabetes mellitus (DM) increased the risk of pancreatic cancer and whether anti-diabetic drugs reduced the risk in Taiwan. METHODS:We designed a population-based cohort study using the Taiwan National Health Insurance Database, which consisted of 49,803 patients aged ...

journal_title：Journal of gastroenterology and hepatology

authors： Liao KF,Lai SW,Li CI,Chen WC

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Patients with cirrhosis exhibit splanchnic, peripheral and pulmonary vasodilation, which are thought to play a role in increasing portal pressure, promoting sodium retention and determining arterial hypoxaemia. The present study investigated whether these abnormalities are influenced by portal hypertension o...

journal_title：Journal of gastroenterology and hepatology

authors： Luca A,García-Pagán JC,de Lacy AM,Escorsell A,Feu F,Visa J,Bosch J,Rodés J

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND AIM:Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that plays a significant role in tumor development. SPARC has been indicated that promotes tumorigenesis, metastasis, and poor prognosis in prostate cancer and lung cancer. Therefore, we sought to investigate the mol...

journal_title：Journal of gastroenterology and hepatology

authors： Jiang X,Liu F,Wang Y,Gao J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Data on risk of hepatocellular carcinoma (HCC) in patients with Wilson disease are scarce. We determine HCC risk in a well-defined cohort of Wilson patients. METHODS:All patients with a confirmed diagnosis of Wilson disease (Leipzig score ≥ 4) in three Dutch university referral hospitals were inclu...

journal_title：Journal of gastroenterology and hepatology

authors： van Meer S,de Man RA,van den Berg AP,Houwen RH,Linn FH,van Oijen MG,Siersema PD,van Erpecum KJ

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The parasympathetic nervous system (PNS), via neurotransmitter acetylcholine (ACh), modulates fibrogenesis in animal models. However, the role of ACh in human hepatic fibrogenesis is unclear. AIMS:We aimed to determine the fibrogenic responses of human hepatic stellate cells (hHSC) to ACh and the relevance ...

journal_title：Journal of gastroenterology and hepatology

authors： Morgan ML,Sigala B,Soeda J,Cordero P,Nguyen V,McKee C,Mouraliderane A,Vinciguerra M,Oben JA

更新日期：2016-02-01 00:00:00

abstract：:Helicobacter pylori is present in infected patients not only on the gastric epithelial cell surface but also in gastric mucus. We developed a competitive polymerase chain reaction (cPCR) method for quantitative measurement of H. pylori in gastric mucus. The aim of this study was to determine the number of H. pylori in...

journal_title：Journal of gastroenterology and hepatology

authors： Furuta T,Takashima M,Futami H,Arai H,Hanai H,Kaneko E

更新日期：1998-05-01 00:00:00

abstract：:The reproducibility of echo-Doppler measurements of portal vein and superior mesenteric artery blood flow has not been extensively studied. In the present study, two groups of subjects were examined to test inter- and intra-observer reproducibility. Each study population consisted of 15 nonportal hypertensive and 15 p...

journal_title：Journal of gastroenterology and hepatology

authors： Iwao T,Toyonaga A,Shigemori H,Oho K,Sumino M,Sato M,Tanikawa K

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The etiology of achalasia is still unknown. The aim of the present study was to elucidate its underlying pathologies and their chronology by investigation of esophageal specimens in patients undergoing surgery (esophageal resection or myotomy) for achalasia. METHODS:In 17 patients with achalasia, histopatho...

journal_title：Journal of gastroenterology and hepatology

authors： Gockel I,Bohl JR,Doostkam S,Eckardt VF,Junginger T

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND AND AIM:Covered metallic stents (CMSs) were developed to overcome tumor ingrowth in uncovered metallic stents (UMSs) for malignant biliary obstruction, but superiority of CMSs over UMSs is still controversial due to the high migration rate in CMS. Therefore, we conducted this retrospective analysis to clarif...

journal_title：Journal of gastroenterology and hepatology

authors： Nakai Y,Isayama H,Kogure H,Hamada T,Togawa O,Ito Y,Matsubara S,Arizumi T,Yagioka H,Mizuno S,Sasaki T,Yamamoto N,Hirano K,Tada M,Koike K

更新日期：2014-09-01 00:00:00

abstract：:Antipyrine metabolism is widely used as an index of the drug-metabolizing reserve of the liver. It is well known that metabolism of this drug is impaired in subjects with acute hepatitis or cirrhosis, but conflicting data have been reported regarding patients with chronic postinfectious hepatitis or liver cancer. We s...

journal_title：Journal of gastroenterology and hepatology

authors： Grieco A,Castellano R,Matera A,Marcoccia S,Di Rocco P,Ragazzoni E,Vecchio FM,Gasbarrini G

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND AIM:There are few studies investigating the treatment of hepatitis C virus (HCV) infection in current and former drug users. With this in mind, we sought to evaluate the antiviral efficacy of interferon alpha-2b (IFN alpha-2b) or pegylated-interferon alpha-2b (PEG-IFN alpha-2b) and ribavirin (RBV) in inj...

journal_title：Journal of gastroenterology and hepatology

authors： Grebely J,Raffa JD,Meagher C,Duncan F,Genoway KA,Khara M,McLean M,Mead A,Viljoen M,DeVlaming S,Fraser C,Conway B

更新日期：2007-09-01 00:00:00

abstract：:The Asia-Pacific Expert Committee on Hepatitis B Management recently reviewed the impact of hepatitis B in the region and assessed the differences and similarities observed in the practical management of the disease in individual Asia-Pacific countries. Hepatitis B is a major health concern in the Asia-Pacific region,...

journal_title：Journal of gastroenterology and hepatology

authors： Mohamed R,Desmond P,Suh DJ,Amarapurkar D,Gane E,Guangbi Y,Hou JL,Jafri W,Lai CL,Lee CH,Lee SD,Lim SG,Guan R,Phiet PH,Piratvisuth T,Sollano J,Wu JC

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND AND AIM:Disease activity and severity of ulcerative colitis (UC) is assessed using colonoscopy, which is invasive, costly and has poor patient acceptability. The role of non-invasive biomarkers of intestinal inflammation in the evaluation of patients with UC is not known. The aim of the study was to examine ...

journal_title：Journal of gastroenterology and hepatology

authors： Masoodi I,Kochhar R,Dutta U,Vaishnavi C,Prasad KK,Vaiphei K,Kaur S,Singh K

更新日期：2009-11-01 00:00:00

abstract：:A 54-year-old woman who was being treated with 10 million units (mu) of natural interferon (IFN)-alpha per day for chronic active hepatitis C at a local clinic, developed coma on the fourth day of treatment. On admission to Yamagata University Hospital, she was still in a state of semicoma with severe hyponatraemia (1...

journal_title：Journal of gastroenterology and hepatology

authors： Mabe K,Shinzawa H,Yamatani K,Takeda T,Ishibashi M,Yamada N,Misawa H,Wakabayashi H,Togashi H,Takahashi T

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND AND AIM:Delayed gastric emptying occurs in more than 50% of chronic diabetic patients, and this is associated with significant impairments in quality of life. Traditional therapy for delayed gastric emptying has focused on supportive treatment, and there is no significant effective therapy. The effect of low...

journal_title：Journal of gastroenterology and hepatology

authors： Wu KL,Chiu YC,Yao CC,Tsai CE,Hu ML,Kuo CM,Tai WC,Chuah SK,Hsiao CC

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Habitual alcohol intake is known to aggravate the clinical outcome of hepatitis C virus (HCV)-related chronic liver diseases and to increase the risk of hepatocellular carcinoma. METHODS:To investigate the possible mechanism of these effects by alcohol, we examined 31 cases of HCV-related chronic liver dise...

journal_title：Journal of gastroenterology and hepatology

authors： Takahashi K,Takahashi T,Takahashi S,Watanabe K,Boku S,Matsui S,Arai F,Asakura H

更新日期：2001-04-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major cause of hepatocellular carcinoma (HCC) and chronic liver disease worldwide. Recent developments and advances in HCV replication systems in vitro and in vivo, transgenic animal models, and gene expression profiling approaches have provided novel insights into the mechanisms...

journal_title：Journal of gastroenterology and hepatology

authors： Yamashita T,Honda M,Kaneko S

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The high recurrence of hepatolithiasis and high operative trauma of hepatectomy necessitate new therapeutic approaches. Thus, this study was designed to (i) investigate the effectiveness of chemical biliary duct embolization (CBDE) for chemical hepatectomy; and (ii) to determine the mechanism of CBD...

journal_title：Journal of gastroenterology and hepatology

authors： Li FY,Cheng JQ,Li N,He S,Zhang MM,Dong JH,Jiang LS,Cheng NS

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIM:Postoperative abdominal adhesion formation is a troublesome clinical problem and a common cause of intestinal obstruction, chronic pain and infertility. The aim of this study was to evaluate the effect of small bowel obstruction (SBO) on functional outcome and quality of life (QOL) in patients who ex...

journal_title：Journal of gastroenterology and hepatology

authors： Erkek AB,Remzi FH,Hammel JP,Akyuz M,Fazio VW

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND AND AIM:Liver fibrosis is an established determinant of prognosis and therapy in chronic hepatitis B (CHB). The role of fibroscan in assessing fibrosis in CHB remains unclear. Present study was designed to correlate fibroscan with liver biopsy and determine whether fibroscan can avoid liver biopsy in patient...

journal_title：Journal of gastroenterology and hepatology

authors： Goyal R,Mallick SR,Mahanta M,Kedia S,Shalimar,Dhingra R,Sharma H,Das P,Datta Gupta S,Panda S,Acharya SK

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND AIM:In the condition of high prevalence of non-alcoholic fatty liver disease (NAFLD), a new diagnostic algorithm to efficiently identify NAFLD patients with significant fibrosis is urgently required. We evaluated the predictive ability of the fibrosis-4 index (FIB-4 index) for significant liver fibrosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Tomeno W,Imajo K,Kuwada Y,Ogawa Y,Kikuchi M,Honda Y,Kato T,Kessoku T,Kirikoshi H,Yoneda M,Kitahora T,Saito S,Ozawa Y,Nakajima A

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND AIM:The activation of Rho proteins has been shown to lead to loss of polarity in cancer cells, as well as reorganization of the cytoskeleton and facilitation of cell motility, possibly resulting in their malignant potential. The clinicopathological significance of RhoA, however, is not yet well known in ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang D,Dou K,Xiang H,Song Z,Zhao Q,Chen Y,Li Y

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Both clinical outcomes and factors predictive for poor response after an initial course of corticosteroids have not yet been well established in the treatment of moderate to severe ulcerative colitis (UC). We therefore evaluated the short- and long-term effects of corticosteroids and prognostic fact...

journal_title：Journal of gastroenterology and hepatology

authors： Yoon JY,Cheon JH,Park JJ,Hong SP,Kim TI,Kim WH

更新日期：2011-07-01 00:00:00