Secreted protein acidic and rich in cysteine promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells and acquisition of cancerstem cell phenotypes.

abstract：:Ulcerative colitis (UC) and Crohn's disease (CD) comprise the idiopathic inflammatory bowel diseases (IBD) of the gut. The etiology of IBD is poorly understood, but an autoimmune disturbance has been suggested to play an important role in this incurable disease. Extracorporeal leukocytapheresis (CAP) is an additional ...

journal_title：Journal of gastroenterology and hepatology

authors： Fukunaga K,Matsumoto T

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND AIM:Approximately 42-95% of working channels have been reported to show the presence of residual fluid despite endoscope reprocessing. The aim of this study was to design two novel protocols for cleaning residual simethicone and demonstrate its efficiency by evaluating the residual fluid and cleanliness ...

journal_title：Journal of gastroenterology and hepatology

authors： Peng CL,Liu TC,Wang HP,Chang WK

更新日期：2020-12-03 00:00:00

abstract：:Antipyrine metabolism is widely used as an index of the drug-metabolizing reserve of the liver. It is well known that metabolism of this drug is impaired in subjects with acute hepatitis or cirrhosis, but conflicting data have been reported regarding patients with chronic postinfectious hepatitis or liver cancer. We s...

journal_title：Journal of gastroenterology and hepatology

authors： Grieco A,Castellano R,Matera A,Marcoccia S,Di Rocco P,Ragazzoni E,Vecchio FM,Gasbarrini G

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND AND AIM:KRAS mutation analysis may provide ancillary diagnostic yield in an endoscopic ultrasound (EUS)-guided histopathological evaluation. We evaluated the clinical impact of KRAS mutation analysis with cytological and histological evaluations in EUS-guided tissue sampling, using a core biopsy needle for s...

journal_title：Journal of gastroenterology and hepatology

authors： Choi HJ,Moon JH,Kim HK,Lee YN,Lee TH,Cha SW,Cho YD,Park SH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Spontaneous bacterial peritonitis (SBP) is a serious complication of cirrhosis with ascites, having high recurrence despite antibiotic prophylaxis. Small bowel dysmotility and bacterial overgrowth have been documented to be related to SBP. The purpose of the present paper was (i) to study whether addition of...

journal_title：Journal of gastroenterology and hepatology

authors： Sandhu BS,Gupta R,Sharma J,Singh J,Murthy NS,Sarin SK

更新日期：2005-04-01 00:00:00

abstract：:Worldwide the need for effective therapy for chronic hepatitis B is similar to that for chronic hepatitis C. Current licensed treatment for chronic hepatitis B (interferon (IFN)-alpha, lamivudine) does not significantly alter the natural history of the disease because the frequency of sustained response is too low; ho...

journal_title：Journal of gastroenterology and hepatology

authors： Schalm SW,De Man RA,Janssen HL

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND AIM:It has recently been reported that Toll-like receptor 4 (TLR4) is involved in cellular responses to lipopolysaccharides (LPS) and early liver injury induced by LPS. The aim of the present study was to investigate the alterations of TLR4 gene expression in liver tissues and Kupffer cells during the co...

journal_title：Journal of gastroenterology and hepatology

authors： Hua J,Qiu DK,Li JQ,Li EL,Chen XY,Peng YS

更新日期：2007-06-01 00:00:00

abstract：BACKGROUNDS AND AIM:Clarithromycin (CAM)-resistant Helicobacter pylori sometimes offers serious problems with eradication by antibiotics. The aim of this study was to determine whether a probiotic can be an alternative therapy in CAM-resistant Hp infection. METHODS:The effects of Lactobacillus gasseri (strain OLL2716)...

journal_title：Journal of gastroenterology and hepatology

authors： Ushiyama A,Tanaka K,Aiba Y,Shiba T,Takagi A,Mine T,Koga Y

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND AIM:Fecal calprotectin (FC) has become a reliable biomarker for intestinal inflammation in inflammatory bowel diseases (IBDs). However, a simple and rapid assay to replace conventional ELISA is necessary for wider use in clinical practice. In this study, we investigated the usefulness of a novel method f...

journal_title：Journal of gastroenterology and hepatology

authors： Inoue K,Aomatsu T,Yoden A,Okuhira T,Kaji E,Tamai H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIM:The role of hypoxia-inducible factor-1α (HIF-1α) and hypoxia-inducible factor-2α (HIF-2α) has been implicated in the clinical prognosis of hepatocellular carcinoma (HCC), but the results remain controversial. We aim to investigate the association of HIF-1α and HIF-2α overexpression with the prognosis...

journal_title：Journal of gastroenterology and hepatology

authors： Ding ZN,Dong ZR,Chen ZQ,Yang YF,Yan LJ,Li HC,Liu KX,Yao CY,Yan YC,Yang CC,Li T

更新日期：2021-01-04 00:00:00

abstract：BACKGROUND AND AIM:Helicobacter pylori (H. pylori) infection is a strong risk factor for the development of gastric cancer. In 2013, the Japanese government approved H. pylori eradication therapy in patients with chronic gastritis as well as peptic ulcer. However, the continuing decline in eradication rates for first-l...

journal_title：Journal of gastroenterology and hepatology

authors： Kawai T,Takahashi S,Suzuki H,Sasaki H,Nagahara A,Asaoka D,Matsuhisa T,Masaoaka T,Nishizawa T,Suzuki M,Ito M,Kurihara N,Omata F,Mizuno S,Torii A,Kawakami K,Ohkusa T,Tokunaga K,Mine T,Sakaki N

更新日期：2014-12-01 00:00:00

abstract：:Viral hepatitis is defined as a hepatitis virus infection in which hepatic inflammation and necrosis lead to a characteristic feature. It is caused by at least five viral agents with specific epidemiological attributes and distinctive immunoserologic findings. The well-characterized forms are hepatitis A, B, C, D and ...

journal_title：Journal of gastroenterology and hepatology

authors： Nishioka M,Morshed SA

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The bacterial beta-glucuronidase (bBG) can deconjugate conjugated bilirubin to form calcium bilirubinate gallstone. Yet, the role of the human biliary beta-glucuronidase (hBG) in the pathogenesis of pigment gallstone formation still remains unsolved. METHODS:Hepatic bile was collected from bile-duc...

journal_title：Journal of gastroenterology and hepatology

authors： Chen CY,Shiesh SC,Tsao HC,Lin XZ

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND AND AIM:Liver fibrosis is an established determinant of prognosis and therapy in chronic hepatitis B (CHB). The role of fibroscan in assessing fibrosis in CHB remains unclear. Present study was designed to correlate fibroscan with liver biopsy and determine whether fibroscan can avoid liver biopsy in patient...

journal_title：Journal of gastroenterology and hepatology

authors： Goyal R,Mallick SR,Mahanta M,Kedia S,Shalimar,Dhingra R,Sharma H,Das P,Datta Gupta S,Panda S,Acharya SK

更新日期：2013-11-01 00:00:00

abstract：:Although the incidence of bleeding from gastric varices is relatively low (10%-36%), the bleeding is massive once it has occurred and it increases the patient's mortality. The management of esophageal variceal bleeding is highly differentiated with several effective treatments available. In contrast, bleeding from gas...

journal_title：Journal of gastroenterology and hepatology

authors： Hashizume M,Akahoshi T,Tomikawa M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIM:The presence of perianal disease in Crohn's disease patients is one of the factors of postoperative recurrence. The aim of this study is to evaluate long-term prognosis of perianal Crohn's disease patients in Asian. METHODS:Patients with Crohn's disease who had undergone surgical bowel resection wer...

journal_title：Journal of gastroenterology and hepatology

authors： Han YM,Kim JW,Koh SJ,Kim BG,Lee KL,Im JP,Kim JS,Jung HC

更新日期：2016-08-01 00:00:00

abstract：:At Royal Perth Hospital, Western Australia in April 1982, spiral bacteria were first cultured from a gastric biopsy specimen. Several important taxonomic features were identified which indicated that these bacteria represented a new genus. In October 1989 the new genus name Helicobacter was published. Helicobacter pyl...

journal_title：Journal of gastroenterology and hepatology

authors： Goodwin CS

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND AND AIM:The attenuated antisecretory activity observed during continuous administration of ranitidine has been described as tolerance. However, it remains unclear whether a similar phenomenon occurs with other histamine H2 receptor antagonists (H2RA). We investigated whether tolerance to famotidine, a strong...

journal_title：Journal of gastroenterology and hepatology

authors： Komazawa Y,Adachi K,Mihara T,Ono M,Kawamura A,Fujishiro H,Kinoshita Y

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND AND AIM:The fibrosis stage of non-alcoholic fatty liver disease (NAFLD) is closely associated with long-term prognosis, including liver-related mortality. However, it is not yet clear whether noninvasive fibrosis markers can predict the incidence of non-liver-related complications in Japanese NAFLD. In this ...

journal_title：Journal of gastroenterology and hepatology

authors： Ito T,Ishigami M,Ishizu Y,Kuzuya T,Honda T,Hayashi K,Nishimura D,Toyoda H,Kumada T,Goto H,Hirooka Y

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIM:The oral manifestations of familial adenomatous polyposis (FAP) have been reported in the recent literature. Therefore, there has been growing interest in the characterization of the dento-osseous anomalies because they may precede colorectal cancer and may be used as a diagnostic marker. This system...

journal_title：Journal of gastroenterology and hepatology

authors： Almeida FT,Pachêco-Pereira C,Porporatti AL,Flores-Mir C,Leite AF,De Luca Canto G,Guerra EN

更新日期：2016-03-01 00:00:00

abstract：:We have previously established a cell damage model, with damage induced by either acid or pepsin treatment for 30 min, involving a rat gastric epithelial cell line (RGM1). In the present study, pretreatment of cells with epidermal growth factor (EGF; 0.1-10 ng/mL) or sucralfate (0.1-3 mg/mL) for 4 h prevented such cel...

journal_title：Journal of gastroenterology and hepatology

authors： Furukawa O,Okabe S

更新日期：1997-05-01 00:00:00

abstract：:Infiltrating leucocytes are activated to generate reactive oxygen species or to produce several molecules in inflamed colonic mucosa. To clarify the phenotypical and functional properties of activating cells in colitic mucosa, 23 patients with ulcerative colitis and 13 controls were studied using a combined method for...

journal_title：Journal of gastroenterology and hepatology

authors： Oshitani N,Sawa Y,Hara J,Adachi K,Nakamura S,Matsumoto T,Arakawa T,Kuroki T

更新日期：1997-12-01 00:00:00

abstract：:The transjugular intrahepatic portosystemic stent-shunt (TIPS) technique consists of a transhepatic puncture of the portal vein and stenting of the parenchymal tract between the hepatic and portal veins. Complications of both puncture and stenting are observed in approximately 5% of procedures. Most of the complicatio...

journal_title：Journal of gastroenterology and hepatology

authors： Rössle M,Haag K,Blum HE

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND AND AIM:This study was designed to determine whether non-alcoholic fatty liver disease (NAFLD), with or without metabolic syndrome (MetS), is a risk factor for cancer development. METHODS:We conducted a retrospective longitudinal study at the Center for Preventive Medicine, St. Luke's International Hospital...

journal_title：Journal of gastroenterology and hepatology

authors： Yamamoto K,Ikeya T,Okuyama S,Fukuda K,Kobayashi D

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND AND AIMS:Data on risk of hepatocellular carcinoma (HCC) in patients with Wilson disease are scarce. We determine HCC risk in a well-defined cohort of Wilson patients. METHODS:All patients with a confirmed diagnosis of Wilson disease (Leipzig score ≥ 4) in three Dutch university referral hospitals were inclu...

journal_title：Journal of gastroenterology and hepatology

authors： van Meer S,de Man RA,van den Berg AP,Houwen RH,Linn FH,van Oijen MG,Siersema PD,van Erpecum KJ

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to clinicopathologically distinguish the pathogenesis of gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma without a MALT lymphoma component (DLL). METHODS:We investigated clinicopathological features of these gastric lymphomas inc...

journal_title：Journal of gastroenterology and hepatology

authors： Hiyama T,Haruma K,Kitadai Y,Masuda H,Miyamoto M,Ito M,Kamada T,Tanaka S,Uemura N,Yoshihara M,Sumii K,Shimamoto F,Chayama K

更新日期：2001-07-01 00:00:00

abstract：:The Korean College of Helicobacter and Upper Gastrointestinal Research first developed guidelines for the diagnosis and treatment of Helicobacter pylori (H. pylori) infection in 1998, and revised guidelines were proposed in 2009 by the same group. Although the revised guidelines were based on a comprehensive review of...

journal_title：Journal of gastroenterology and hepatology

authors： Kim SG,Jung HK,Lee HL,Jang JY,Lee H,Kim CG,Shin WG,Shin ES,Lee YC,Korean College of Helicobacter and Upper Gastrointestinal Research.

更新日期：2014-01-01 00:00:00

abstract：:Bleeding from hepatocellular carcinoma (HCC) invading the gastrointestinal tract is very uncommon. We report the case of a 61 year old man who had a large bleed from HCC invading the fundus of the stomach. Diagnosis was eventually made at laparotomy and he is still alive 7 months after local resection. ...

journal_title：Journal of gastroenterology and hepatology

authors： Nicoll AJ,Ireton HJ,Crotty B

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND AND AIM:We have previously found high incidence of inflammatory bowel disease (IBD) in Australia. A population-based registry was established to assess disease severity, frequency of complications, and prognostic factors. METHODS:Incident cases were prospectively identified over 4 years. Early disease sever...

journal_title：Journal of gastroenterology and hepatology

authors： Niewiadomski O,Studd C,Hair C,Wilson J,Ding NS,Heerasing N,Ting A,McNeill J,Knight R,Santamaria J,Prewett E,Dabkowski P,Dowling D,Alexander S,Allen B,Popp B,Connell W,Desmond P,Bell S

更新日期：2015-09-01 00:00:00