Effects of hypoxia-inducible factor-1α and hypoxia-inducible factor-2α overexpression on hepatocellular carcinoma survival: A systematic review with meta-analysis.

abstract：BACKGROUND AND AIM:This study aimed to investigate the prognostic value of expression of hepatocyte nuclear factors (HNFs) involved in hepatic gene transcription in patients undergoing curative resection for hepatocellular carcinoma (HCC). METHODS:We performed immunohistochemical analyses on microarrays of the tumors ...

journal_title：Journal of gastroenterology and hepatology

authors： Shim JH,Kang HJ,Han S,Lee YJ,Lee SG,Yu E,Lee HC

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND AIM:The aim of this study was to assess the gastric histopathology and serum gastrin-17 and pepsinogens profiles in patients with duodenal ulcer before and after Helicobacter pylori eradication in a population with a very high prevalence of H. pylori. At the same time we assessed the role of H. pylori de...

journal_title：Journal of gastroenterology and hepatology

authors： Pimanov SI,Makarenko EV,Voropaeva AV,Matveenko ME,Voropaev EV

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND AND AIM:Portal-systemic collateral vascular resistance and vasoconstrictor responsiveness are crucial in portal hypertension and variceal bleeding control. Statins enhance vasodilators production, but their influence on collaterals is unknown. This study aimed to survey the effect of simvastatin on collatera...

journal_title：Journal of gastroenterology and hepatology

authors： Huang HC,Wang SS,Lee JY,Chen YC,Lee FY,Lin HC,Chang CC,Lee SD

更新日期：2010-08-01 00:00:00

abstract：:A novel experimental model of submassive liver necrosis with impaired regeneration has been established. A novel lipid A analogue, FS-112, was injected intravenously into male BALB/c mice, followed 2 days later by a 70% partial hepatectomy. Over the next 9 days, mice became severely jaundiced, with a peak total biliru...

journal_title：Journal of gastroenterology and hepatology

authors： Maeda T,Ohnishi H,Hayashi T,Ishiki Y,Moriwaki H,Muto Y

更新日期：1996-05-01 00:00:00

abstract：:This article highlights the importance of hepatotropic viruses as pathogens in patients undergoing transplantation, their contribution to morbidity and mortality after transplantation and the approach to treatment of these pathogens when they cause disease. Although many advances have been made in the management of vi...

journal_title：Journal of gastroenterology and hepatology

authors： Bzowej NH,Wright TL

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Serum alanine aminotransferase (ALT) is commonly used to detect liver damage. Recent studies indicate that ALT levels at the upper range of normal limits are predictors of adverse outcomes, especially diabetes mellitus (DM) and the metabolic syndrome. The aim of our study was to define the ALT thres...

journal_title：Journal of gastroenterology and hepatology

authors： Shlomai A,Kariv R,Leshno M,Beth-or A,Sheinberg B,Halpern Z

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND AIM:Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) of unknown etiology. We aimed to identify the etiological agent of CD using a molecular cloning strategy that was particularly focused on identifying agents causing immune abnormalities and infectious agents. METHODS:We constructed a...

journal_title：Journal of gastroenterology and hepatology

authors： Iizuka M,Nakagomi O,Nanjo H,Chiba M,Fukushima T,Sugita A,Sagara S,Horie Y,Watanabe S

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND AND AIM:This multinational (Taiwan, South Korea, Russia) phase 3 study evaluated the all-oral, ribavirin-free, fixed-dose combination (DCV-TRIO) of daclatasvir (NS5A inhibitor) 30 mg, asunaprevir (NS3 inhibitor) 200 mg, and beclabuvir (NS5B inhibitor) 75 mg, in patients with chronic hepatitis C virus genotyp...

journal_title：Journal of gastroenterology and hepatology

authors： Kao JH,Yu ML,Peng CY,Heo J,Chu CJ,Chang TT,Lee YJ,Hu TH,Yoon KT,Paik SW,Lim YS,Ahn SH,Isakov V,McPhee F,Hu W,Scott Swenson E,Yin PD,Treitel M

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND AIM:Epithelial-mesenchymal transition (EMT) of biliary epithelial cells (BECs) plays an important role in biliary fibrosis. This study investigated the effects of simvastatin on the lipopolysaccharide (LPS)-induced EMT and related signal pathways in BECs. METHODS:Biliary epithelial cells were exposed to...

journal_title：Journal of gastroenterology and hepatology

authors： Kim Y,Lee EJ,Jang HK,Kim CH,Kim DG,Han JH,Park SM

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND AIM:  The clinical utility of capsule endoscopy (CE) is often limited by incomplete small-bowel transit. The aim was to determine whether the use of an external real-time viewer could reduce delays caused by delayed gastric emptying of the capsule or delayed intestinal transit and also improve the rate o...

journal_title：Journal of gastroenterology and hepatology

authors： Shiotani A,Honda K,Kawakami M,Nishi R,Murao T,Ishii M,Matsumoto H,Kusunoki H,Hata J,Haruma K

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Microbial agents are a possible cause of ulcerative colitis. We have previously reported evidence of bacteria invading the colonic mucosa of patients with ulcerative colitis. We have isolated bacteria from inflamed colonic mucosa, examined the localization of the species in the mucosa, and assayed for serum ...

journal_title：Journal of gastroenterology and hepatology

authors： Ohkusa T,Sato N,Ogihara T,Morita K,Ogawa M,Okayasu I

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Significant changes in hepatic haemodynamics occur after major hepatectomy, but the pathogenesis of this phenomenon is unclear. This study investigates the serum profile of prostaglandin and nitric oxide in the hepatic and systemic circulation before and after hepatectomy and the temporal relationsh...

journal_title：Journal of gastroenterology and hepatology

authors： Lai OF,Chow PK,Tan S,Song IC,Soo KC,Aw SE,Yu WK,Fook-Chong SM,Satchithanantham S,Chan ST

更新日期：2000-08-01 00:00:00

abstract：:Hepatitis B virus (HBV) infection remains a major issue among dialysis patients. It is associated with a high risk of hepatic complication. The liver disease runs a unique clinical course in dialysis patients, as it can progress with modest hepatic inflammation and prominent fibrosis. The conventional cut-off level of...

journal_title：Journal of gastroenterology and hepatology

authors： Wong PN,Fung TT,Mak SK,Lo KY,Tong GM,Wong Y,Loo CK,Lam EK,Wong AK

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) ranks third of all cancer mortalities in Hong Kong. CRC screening can reduce mortality. However, participation in the CRC screening program depends on the knowledge and attitude of the population. The aim of this study is to investigate the knowledge and attitude towards CRC screening...

journal_title：Journal of gastroenterology and hepatology

authors： Wong BC,Chan AO,Wong WM,Hui WM,Kung HF,Lam SK

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND AIM:Chronic alcoholic liver disease is associated with hepatic insulin resistance, dysregulated lipid metabolism with increased toxic lipid (ceramide) accumulation, lipid peroxidation, and oxidative and endoplasmic reticulum (ER) stress. Peroxisome-proliferator activated receptor (PPAR) agonists are insu...

journal_title：Journal of gastroenterology and hepatology

authors： Ramirez T,Tong M,Chen WC,Nguyen QG,Wands JR,de la Monte SM

更新日期：2013-01-01 00:00:00

abstract：:Following the development of tests for hepatitis C virus and hepatitis E virus infection, it became clear that there remained cases of hepatitis that were non-A-E. Such cases provided impetus for the search for additional hepatitis viruses and, by using molecular techniques, several candidates were identified. An ente...

journal_title：Journal of gastroenterology and hepatology

authors： Bowden S

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence of ulcerative colitis (UC) is increasing steadily in Japan. In Western countries, a bimodal distribution, with UC onset peaks in youth and middle age, is observed, and smoking cessation is reported as a risk factor for UC. However, there are few reports on a bimodal distribution of ons...

journal_title：Journal of gastroenterology and hepatology

authors： Takahashi H,Matsui T,Hisabe T,Hirai F,Takatsu N,Tsurumi K,Kanemitsu T,Sato Y,Kinjyo K,Yano Y,Takaki Y,Nagahama T,Yao K,Washio M

更新日期：2014-08-01 00:00:00

abstract：:The key issues that determine the decision between reusable versus disposable accessories are cost and functionality. In most health-care systems the availability and dissemination of endoscopic services relates directly to the resources (i.e. budget) of that system. Given the limitations of health-care budgets, acces...

journal_title：Journal of gastroenterology and hepatology

authors： Haber G

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori causes chronic gastritis, peptic ulcer, gastric cancer and mucosa-associated lymphoid tissue (MALT) lymphoma. Different genotypes of H. pylori are confirmed from diverse geographical areas. Its association with clinical diseases remains controversial. The aim of the present study was to i...

journal_title：Journal of gastroenterology and hepatology

authors： Perng CL,Lin HJ,Sun IC,Tseng GY,Facg

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND AIM:Opioid-induced constipation (OIC) is a frequent adverse event (AE) that impairs patients' quality of life (QOL). Peripherally acting μ-opioid receptor antagonists (PAMORAs) have been recognized as a treatment option for OIC, but the effect consistent across the studies has not been evaluated. METHOD...

journal_title：Journal of gastroenterology and hepatology

authors： Nishie K,Yamamoto S,Yamaga T,Horigome N,Hanaoka M

更新日期：2019-05-01 00:00:00

abstract：:Alcoholic liver diseases (ALD) are frequently associated with iron overload. Until recently, the effects of ethanol in hepatic iron uptake and intestinal iron absorption have not been clarified in detail. Two possible mechanisms for iron overload are the uptake of iron into hepatocytes in a specific manner through the...

journal_title：Journal of gastroenterology and hepatology

authors： Kohgo Y,Ohtake T,Ikuta K,Suzuki Y,Torimoto Y,Kato J

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis C virus (HCV) and environmental hepatotoxins may have an indirect influence on health by altering the synthesis and function of hormones, particularly reproductive hormones. We aimed to evaluate liver diseases and sex steroid hormones in Egypt, which has the highest prevalence of HCV worldw...

journal_title：Journal of gastroenterology and hepatology

authors： Aguilar CE,Soliman AS,McConnell DS,Zekri AR,Banerjee M,Omar A,Sharawy M,Omar S,Raouf A,Sowers MR

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIM:Intubation of the terminal ileum (TI) demonstrates a complete colonoscopy, but its clinical value during screening exams is unknown. We aimed to determine whether TI intubation during screening colonoscopy is associated with colonoscopy quality measures or identifies subclinical pathology. METHODS:W...

journal_title：Journal of gastroenterology and hepatology

authors： Leiman DA,Jawitz NG,Lin L,Wood RK,Gellad ZF

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND AIM:The presence of perianal disease in Crohn's disease patients is one of the factors of postoperative recurrence. The aim of this study is to evaluate long-term prognosis of perianal Crohn's disease patients in Asian. METHODS:Patients with Crohn's disease who had undergone surgical bowel resection wer...

journal_title：Journal of gastroenterology and hepatology

authors： Han YM,Kim JW,Koh SJ,Kim BG,Lee KL,Im JP,Kim JS,Jung HC

更新日期：2016-08-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the major cancers in the world. There is a striking variation in HCC incidence rates between various countries, with a highest-to-lowest ratio of 112.5 for males and 54.7 for females. The high-risk populations are clustered in sub-Saharan Africa and eastern Asia. The male-to-fe...

journal_title：Journal of gastroenterology and hepatology

authors： Chen CJ,Yu MW,Liaw YF

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND AND AIM:Although gastric hypermotility is one of the mechanisms proposed to explain the ulcerogenic action of indomethacin, the drug has shown relaxatory effects on isolated longitudinal and transverse rat gastric fundus. To explain the above discrepancy, the aim of this study was to investigate the effects ...

journal_title：Journal of gastroenterology and hepatology

authors： Keshavarz M,Afshin S,Djahanguiri B

更新日期：2007-09-01 00:00:00

abstract：:Lymphocytic (microscopic) colitis is a disease of unknown aetiology which manifests as long-standing intermittent diarrhoea. Diagnosis is confirmed on histological examination of the colon. An association of this uncommon disease with tropical sprue is described. Tetracycline therapy resulted in a favourable clinical ...

journal_title：Journal of gastroenterology and hepatology

authors： Puri AS,Khan EM,Kumar M,Pandey R,Choudhuri G

更新日期：1994-01-01 00:00:00

abstract：:Acid-sensing pathways, which trigger mucosal defense mechanisms in response to luminal acid, involve the rapid afferent-mediated "capsaicin pathway" and the sustained "prostaglandin (PG) pathway." Luminal acid quickly increases protective PG synthesis and release from epithelia, although the mechanism by which luminal...

journal_title：Journal of gastroenterology and hepatology

authors： Akiba Y,Kaunitz JD

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known about the role of hepatitis B virus (HBV) factors in the long-term prognosis of hepatocellular carcinoma (HCC) after resection. The objective of the present study was to identify the changing patterns of HBV levels and its effect on outcome after resection. METHODS:This study recruit...

journal_title：Journal of gastroenterology and hepatology

authors： An HJ,Jang JW,Bae SH,Choi JY,Cho SH,Yoon SK,Han JY,Lee KH,Kim DG,Jung ES

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND AIMS:We have recently reported quantitative and qualitative differences of the bone marrow (BM) hematopoietic progenitor cells in autoimmune hepatitis type-1 (AIH-1) and primary biliary cirrhosis (PBC). In order to better investigate the possible involvement of BM in these diseases, we studied the morpho...

journal_title：Journal of gastroenterology and hepatology

authors： Tsikrikoni A,Rigopoulou EI,Zachou K,Liaskos C,Kyriakou D,Dalekos GN

更新日期：2008-08-01 00:00:00