Prognostic importance of fucosylated alpha-fetoprotein in hepatocellular carcinoma patients with low alpha-fetoprotein.

abstract：BACKGROUND AND AIMS:Non-alcoholic fatty liver disease (NAFLD) is an emerging problem in the Asia-Pacific region. However, its prevalence and risk factors in Asian (especially South Asian) communities is poorly studied. In this study, the aim was to determine the community prevalence and risk factors for NAFLD among adu...

journal_title：Journal of gastroenterology and hepatology

authors： Dassanayake AS,Kasturiratne A,Rajindrajith S,Kalubowila U,Chakrawarthi S,De Silva AP,Makaya M,Mizoue T,Kato N,Wickremasinghe AR,de Silva HJ

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIM:Early life exposure to the famine may affect the susceptibility to the metabolic disorders. The objective of this study was to examine the associations of early life exposure to the Chinese Famine (1959-1961) with the risk of fatty liver disease, obesity, hypertension, and hyperglycemia in adulthood....

journal_title：Journal of gastroenterology and hepatology

authors： Chen JP,Peng B,Tang L,Sun R,Hu S,Wen XY,Que P,Wang YH

更新日期：2016-01-01 00:00:00

abstract：:Better understanding of hepatitis B virus (HBV) replication and the natural history and immunopathogenesis of chronic hepatitis B, together with the introduction of effective agents with different mechanisms of action, is the basis for better therapeutic strategies against chronic hepatitis B. Substantial experience h...

journal_title：Journal of gastroenterology and hepatology

authors： Liaw YF

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:The relationship between Helicobacter pylori eradication and gastric emptying has been reported; however, the effect of eradication therapy on gastric emptying is still unclear. This study evaluated the relationship between three gastric emptying techniques, the scintigraphic technique, the 13C-octanoic acid...

journal_title：Journal of gastroenterology and hepatology

authors： Kachi M,Shirasaka D,Aoyama N,Ebara S,Miki I,Morita Y,Tamura T,Kasuga M

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIM:The purpose of this study was to describe the computed tomography (CT) findings of sorafenib-treated hepatic tumors in patients with advanced hepatocellular carcinoma and to correlate the findings to the overall survival (OS). METHODS:Twenty-eight sorafenib-treated patients who had advanced hepatoce...

journal_title：Journal of gastroenterology and hepatology

authors： Kim MJ,Choi JI,Lee JS,Park JW

更新日期：2011-07-01 00:00:00

abstract：:Humans and Helicobacter pylori have evolved and adapted over tens of thousands of years. Yet peptic ulcer disease appeared to be rare prior to the 19th century. The prevalence of peptic ulcer disease increased between 1850 and 1900 and culminated in a cohort at high risk that was born at the end of the 19th century. T...

journal_title：Journal of gastroenterology and hepatology

authors： Roberts-Thomson IC

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Regional variations in inflammatory bowel disease (IBD) rates have been observed. Limited epidemiological data are available from Australasia. IBD prevalence rates have never been assessed in an Australian population-based setting. In addition, there are few historical IBD incidence data to allow as...

journal_title：Journal of gastroenterology and hepatology

authors： Studd C,Cameron G,Beswick L,Knight R,Hair C,McNeil J,Desmond P,Wilson J,Connell W,Bell S

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Low-grade erosive esophagitis (i.e. Los Angeles grade A) is the most predominant type of esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational stud...

journal_title：Journal of gastroenterology and hepatology

authors： Amano Y,Yamashita H,Koshino K,Ohshima T,Miwa H,Iwakiri R,Fujimoto K,Manabe N,Haruma K,Kinoshita Y

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIM:Repeated water avoidance stress (WAS) induces visceral hypersensitivity. Additionally, it is also known to activate corticotropin-releasing factor (CRF), mast cells, and pro-inflammatory cytokines systems, but their precise roles on visceral sensation have not been determined definitely. The aim of t...

journal_title：Journal of gastroenterology and hepatology

authors： Nozu T,Miyagishi S,Nozu R,Takakusaki K,Okumura T

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND AIM:The number of colonoscopies required to reach satisfactory adenoma detection rate (ADR) is not well established. The aim of this study was to identify the appropriate number of procedures required to attain satisfactory ADR for those well-trained endoscopists who have a cecal intubation rate (CIR) ≥ ...

journal_title：Journal of gastroenterology and hepatology

authors： Dong Z,Sun H,Li B,Zhang Q,Sun K,Wang Z,Qian X,Wang J,Zhan T,Jiang Y,Chen Y,Xu S

更新日期：2020-10-26 00:00:00

abstract：BACKGROUND:Spontaneous bacterial peritonitis (SBP) is a serious complication of cirrhosis with ascites, having high recurrence despite antibiotic prophylaxis. Small bowel dysmotility and bacterial overgrowth have been documented to be related to SBP. The purpose of the present paper was (i) to study whether addition of...

journal_title：Journal of gastroenterology and hepatology

authors： Sandhu BS,Gupta R,Sharma J,Singh J,Murthy NS,Sarin SK

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND AND AIM:Radiation-induced colitis is a common clinical problem associated with radiotherapy and accidental exposure to ionizing radiation. Goblet cells play a pivotal role in the intestinal barrier against pathogenic bacteria. Rebamipide, an anti-gastric ulcer drug, has the effects to promote goblet cell pro...

journal_title：Journal of gastroenterology and hepatology

authors： Jang H,Park S,Lee J,Myung JK,Jang WS,Lee SJ,Myung H,Lee C,Kim H,Lee SS,Jin YW,Shim S

更新日期：2018-04-01 00:00:00

abstract：:The main goals of chronic hepatitis B treatment should be the long-term suppression of viral replication to minimize disease progression and the risk for the development of hepatocellular carcinoma. Treatment end-points, depending on surrogate markers alone, in particular hepatitis B e-antigen seroconversion, may not ...

journal_title：Journal of gastroenterology and hepatology

authors： Fung J,Lai CL,Yuen MF

更新日期：2008-08-01 00:00:00

abstract：:To evaluate the pathophysiology underlying gastric mucosal lesions induced by lateral hypothalamic (LH) lesions, we investigated the changes in acid secretion, gastric mucosal blood flow, gastric mucus and mucosal integrity in the corpus during the 4 h period and 48 h after the production of bilateral electrolytic LH ...

journal_title：Journal of gastroenterology and hepatology

authors： Saita H,Murakami M,Kita T

更新日期：1995-07-01 00:00:00

abstract：:The liver is an active site for the biosynthesis of haem and porphyrinogens/porphyrins, which are intermediates of the haem biosynthetic pathway, because haem is required for functional activity of the cytochrome P 450 system and other critical hepatic haemoproteins. The production of hepatic haem is regulated primari...

journal_title：Journal of gastroenterology and hepatology

authors： Bloomer JR

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Disorders of the motor function of the upper gastrointestinal tract have been implicated in the pathogenesis of non-ulcer dyspepsia. Approximately 50% of patients with abdominal symptoms (without ulcer) have normal gastric emptying. Apart from gastric emptying, other mechanisms are very important in the etio...

journal_title：Journal of gastroenterology and hepatology

authors： Mizushima T,Sawa K,Ochi K,Tanioka H,Wakuta A,Matsushita K,Shirahige A,Kiura K,Tanimoto M,Koide N,Harada H

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND AIM:The major transporter responsible for bile acid uptake from the intestinal lumen is the apical sodium-dependent bile acid transporter (ASBT, SLC10A2). Analysis of the SLC10A2 gene has identified a variety of sequence variants including coding region single nucleotide polymorphisms (SNPs) that may inf...

journal_title：Journal of gastroenterology and hepatology

authors： Ho RH,Leake BF,Urquhart BL,Gregor JC,Dawson PA,Kim RB

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Colorectal laterally spreading tumors (LST) > 20 mm are usually treated by endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR). Endoscopic piecemeal mucosal resection (EPMR) is sometimes required. The aim of our study was to compare the outcomes of ESD and EMR, including EPM...

journal_title：Journal of gastroenterology and hepatology

authors： Terasaki M,Tanaka S,Oka S,Nakadoi K,Takata S,Kanao H,Yoshida S,Chayama K

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND AIM:Population-based studies on post-colonoscopy colorectal cancer (CRC) from Asia are sparse. We aimed to determine the characteristics and predictive factors and survival of post-colonoscopy CRC in Hong Kong. METHODS:This is a territory-wide retrospective cohort study. Patients aged ≥ 40 years with co...

journal_title：Journal of gastroenterology and hepatology

authors： Cheung KS,Chen L,Seto WK,Leung WK

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Liver biopsy is the gold standard test to determine the grade of fibrosis, but there are associated problems. Because gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid is secreted partially in hepatocytes and bile, it is possible that ethoxybenzyl-magnetic resonance imaging (EOB-MRI) corre...

journal_title：Journal of gastroenterology and hepatology

authors： Nojiri S,Kusakabe A,Fujiwara K,Shinkai N,Matsuura K,Iio E,Miyaki T,Joh T

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND AIM:Host genetic factors have been reported as influencing the progress to fulminant hepatitis (FH). Our previous data showed the serum level of tumor necrosis factor (TNF)-alpha influenced by gene polymorphisms to be markedly increased. It was investigated whether polymorphisms in the IL-10 gene, in add...

journal_title：Journal of gastroenterology and hepatology

authors： Takakura M,Tokushige K,Matsushita N,Hashimoto E,Shiratori K

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatocellular carcinoma (HCC) remains a serious cause of cancer-related deaths worldwide. Developing new therapeutic strategies is urgently needed to improve the outcomes of HCC patients. Dendritic cell (DC)-based vaccines and programmed death 1 (PD-1) immune checkpoint inhibitors have been regarded...

journal_title：Journal of gastroenterology and hepatology

authors： Teng CF,Wang T,Shih FY,Shyu WC,Jeng LB

更新日期：2021-01-19 00:00:00

abstract：AIM:We compared the epidemiology and clinical features of hepatocellular carcinoma (HCC) cases diagnosed between 1975 and 2002. METHODS:Retrospective and prospective analysis was performed of HCC cases diagnosed at The Alfred during the time periods 1975-1983 and 1995-2002. Demographic, epidemiological, clinical and l...

journal_title：Journal of gastroenterology and hepatology

authors： Roberts SK,Kemp W

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:This study aimed to describe the clinical features, manometric findings, prevalence and incidence of achalasia in Singapore. METHODS:A total of 615 new patients referred for oesophageal manometry between 1989 and 1996 were examined prospectively. Twenty-four men and 25 women fulfilled the manometric and cli...

journal_title：Journal of gastroenterology and hepatology

authors： Ho KY,Tay HH,Kang JY

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND AIM:The role of hypoxia-inducible factor-1α (HIF-1α) and hypoxia-inducible factor-2α (HIF-2α) has been implicated in the clinical prognosis of hepatocellular carcinoma (HCC), but the results remain controversial. We aim to investigate the association of HIF-1α and HIF-2α overexpression with the prognosis...

journal_title：Journal of gastroenterology and hepatology

authors： Ding ZN,Dong ZR,Chen ZQ,Yang YF,Yan LJ,Li HC,Liu KX,Yao CY,Yan YC,Yang CC,Li T

更新日期：2021-01-04 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in Western industrialized countries, affecting 20-40% of the general population. Large population-based surveys in China, Japan, and Korea indicate that the prevalence of NAFLD is now 12% to 24% in population subgroups, depending on age, gende...

journal_title：Journal of gastroenterology and hepatology

authors： Chitturi S,Farrell GC,Hashimoto E,Saibara T,Lau GK,Sollano JD,Asia-Pacific Working Party on NAFLD.

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND AIM:The conventional method of anatomical right hemihepatectomy (ARHH) requires hilus dissection. We report a method without hilus dissection to minimize intraoperative bleeding. METHODS:We retrospectively evaluated data of 107 patients who received ARHH involving ligation of corresponding inflow and ou...

journal_title：Journal of gastroenterology and hepatology

authors： Chen XP,Zhang ZW,Huang ZY,Chen YF,Zhang WG,Qiu FZ

更新日期：2011-04-01 00:00:00

abstract：:The anti-pre-S antibody in the samples of sera from normal healthy persons and patients with different clinical types of liver diseases due to hepatitis B virus (HBV) infection was detected by a newly established enzyme-linked immunosorbent assay technique. This test is a blocking assay where anti-pre-S antibody in th...

journal_title：Journal of gastroenterology and hepatology

authors： Irshad M,Gandhi BM,Acharya SK,Joshi YK,Tandon BN

更新日期：1989-01-01 00:00:00

abstract：:In order to identify proguanylin-secreting cells, we have raised an antiserum against the synthetic fragment of human proguanylin (1-15) and have examined the proguanylin-positive cells in the human and rat gastrointestinal tract by immunohistochemical methods. Numerous proguanylin (1-15)-immunoreactive cells were fou...

journal_title：Journal of gastroenterology and hepatology

authors： Ieda H,Naruse S,Furuya S,Ozaki T,Ando E,Nokihara K,Hori S,Kitagawa M,Hayakawa T

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate the effectiveness of peroral endoscopic myotomy (POEM) surgery in achalasia patients with failure of prior pneumatic dilation (PD). METHODS:Twenty-one patients with a history of failed PD were prospectively recruited as the case group, and 30 patients with no history of prior treatmen...

journal_title：Journal of gastroenterology and hepatology

authors： Ling T,Guo H,Zou X

更新日期：2014-08-01 00:00:00