Abstract：
BACKGROUND AND AIM:The number of colonoscopies required to reach satisfactory adenoma detection rate (ADR) is not well established. The aim of this study was to identify the appropriate number of procedures required to attain satisfactory ADR for those well-trained endoscopists who have a cecal intubation rate (CIR) ≥ 90% and start to perform colonoscopy independently. METHODS:All endoscopists with compelete independent colonoscopy data during career in our database were enrolled. The number of procedures required to achieve ADR ≥ 20% was identified by cumulative summation (Cusum), learning curve Cusum (LC-Cusum), and moving average method. Mixed effect logistic regression model was developed to determine the relationship between endoscopist as well as patient-related factors and adenoma detection. RESULTS:A total of 24 943 procedures and 14 endoscopists were enrolled. By Cusum analysis, the interest point was at 207 procedures. By LC-Cusum analysis, 71% (10/14) and 86% (12/14) of endoscopists had attained satisfactory ADR after 200 and 300 procedures, respectively. By moving average method, endoscopists reached a mean ADR of 20% at 216 and 261 procedures over blocks of 50 and 100 procedures, respectively. The total number of procedures, number of daily procedures, patient age and gender, bowel preparation, sedation, and diverticulosis were significantly associated with adenoma detection. CONCLUSIONS:This is the first study to investigate the learning curve of ADR for those well-trained endoscopists who have a CIR ≥ 90% and start to perform colonoscopy independently. Two hundred procedures might be an optimal number required to reach an ADR ≥ 20%.
journal_name
J Gastroenterol Hepatoljournal_title
Journal of gastroenterology and hepatologyauthors
Dong Z,Sun H,Li B,Zhang Q,Sun K,Wang Z,Qian X,Wang J,Zhan T,Jiang Y,Chen Y,Xu Sdoi
10.1111/jgh.15314subject
Has Abstractpub_date
2020-10-26 00:00:00eissn
0815-9319issn
1440-1746pub_type
杂志文章abstract：BACKGROUND AND AIMS:Cancer invasion and metastasis are critical events for patient prognosis; however, the most important step in the whole process of lymph node (LN) metastasis in gastric cancer remains obscure. In this study, the significance of cancer cell behaviors, such as cell detachment, stromal invasion and lym...
journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
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abstract：BACKGROUND AND AIM:Symptoms and complications of primary biliary cirrhosis (PBC) have been shown to impair patients' health-related quality of life (HRQOL) in the West. We aimed to measure the HRQOL and to determine the factors associated with worse HRQOL among the Chinese PBC patients in Hong Kong. METHODS:Chinese pa...
journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/j.1440-1746.2007.05092.x
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abstract：BACKGROUND AND AIMS:The immunogenetic basis of autoimmune diseases has become more and more evident. We have analyzed the human leukocyte antigen (HLA) associations with type-1 autoimmune hepatitis (AIH) among patients from western India. METHODS:In 20 patients and 120 healthy controls, polymerase chain reaction ampli...
journal_title：Journal of gastroenterology and hepatology
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doi：10.1111/j.1440-1746.2004.03608.x
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/j.1440-1746.2008.05680.x
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章,meta分析,评审
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章,多中心研究
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章,评审
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章,评审
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journal_title：Journal of gastroenterology and hepatology
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1046/j.1440-1746.2003.03214.x
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章,评审
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/j.1440-1746.2006.04534.x
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/j.1440-1746.2006.04504.x
更新日期：2007-11-01 00:00:00
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章,评审
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/j.1440-1746.2006.04304.x
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章,随机对照试验
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pub_type： 杂志文章
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章,meta分析,评审
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/j.1440-1746.2007.04949.x
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abstract：:Primary sclerosing cholangitis (PSC), a chronic inflammatory process affecting the extrahepatic and/or medium to large bile ducts, is not rare in children. It has features suggesting an autoimmune pathogenesis, although the mechanism of tissue damage remains unknown. The clinical presentation of childhood primary scle...
journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章,评审
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/j.1440-1746.2011.06734.x
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abstract：BACKGROUND AND AIM:Delayed gastric emptying occurs in more than 50% of chronic diabetic patients, and this is associated with significant impairments in quality of life. Traditional therapy for delayed gastric emptying has focused on supportive treatment, and there is no significant effective therapy. The effect of low...
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pub_type： 杂志文章
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/j.1440-1746.2009.06147.x
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abstract：BACKGROUND AND AIM:The aim of the present study was to evaluate the frequency of complications during endoscopic ultrasound (EUS)-guided drainage of pancreatic fluid collections (PFC), identify contributing factors, and report on management outcomes. METHODS:All patients who underwent EUS-guided PFC drainage over 7 ye...
journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/j.1440-1746.2011.06771.x
更新日期：2011-10-01 00:00:00
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journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1046/j.1440-1746.2001.02567.x
更新日期：2001-09-01 00:00:00
abstract：BACKGROUND AND AIM:DNA methylation is an important epigenetic modification that can promote the development of various cancers. The STAT1 and SOCS3 have been observed to be hypermethylated in tumor tissues and peripheral blood. This study aimed to explore the relationship between the methylation status of the STAT1 and...
journal_title：Journal of gastroenterology and hepatology
pub_type： 杂志文章
doi：10.1111/jgh.15021
更新日期：2020-08-01 00:00:00
