Computed tomography findings of sorafenib-treated hepatic tumors in patients with advanced hepatocellular carcinoma.

abstract：BACKGROUND AND AIM:Patients with non-alcoholic fatty liver disease (NAFLD) have an increased risk of atherosclerosis and alanine aminotransferase (ALT) is associated with insulin resistance independently of metabolic factors. The aim of the present study was to investigate whether NAFLD patients with ALT elevation had ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang CC,Lin SK,Tseng YF,Hsu CS,Tseng TC,Lin HH,Wang LY,Kao JH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Probucol is a lipid-lowering agent with anti-oxidant effects. Oxidative stress and inflammation are important in the pathophysiology of insulin resistance. We aimed to evaluate the effects of probucol on liver histological changes, serum and hepatic levels of adipokines in rats with high fat-induced...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang X,Li Z,Liu D,Xu X,Shen W,Mei Z

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The high recurrence of hepatolithiasis and high operative trauma of hepatectomy necessitate new therapeutic approaches. Thus, this study was designed to (i) investigate the effectiveness of chemical biliary duct embolization (CBDE) for chemical hepatectomy; and (ii) to determine the mechanism of CBD...

journal_title：Journal of gastroenterology and hepatology

authors： Li FY,Cheng JQ,Li N,He S,Zhang MM,Dong JH,Jiang LS,Cheng NS

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND AIM:Hyperphosphatemia has been implicated in the development and treatment of various cancers. However, whether it can be used as a direct prognostic marker of colorectal cancer (CRC) has remained unexplored. Given new insights into the importance of hyperphosphatemia in CRC, we sought to evaluate the as...

journal_title：Journal of gastroenterology and hepatology

authors： Ye Z,Palazzo JP,Lin L,Lai Y,Guiles F,Myers RE,Han J,Xing J,Yang H

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis C virus (HCV)-infected patients who responded to interferon (IFN) treatment with clearance of serum HCV RNA may rarely develop hepatocellular carcinoma (HCC). The aim of the present study was to elucidate the risk factors for liver carcinogenesis among such patients. METHODS:In total, 126 ...

journal_title：Journal of gastroenterology and hepatology

authors： Tokita H,Fukui H,Tanaka A,Kamitsukasa H,Yagura M,Harada H,Okamoto H

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND AIM:There have been few studies in Japan of the utility of quality of life (QOL) questionnaires as an evaluation of chemotherapy for gastrointestinal (GI) cancer. The present study investigated whether QOL can be an indicator of the clinical benefit of chemotherapy, by analyzing the changes in the QOL sc...

journal_title：Journal of gastroenterology and hepatology

authors： Kato J,Nagahara A,Iijima K,Yoshimura M,Osada T,Yoshizawa T,Watanabe S

更新日期：2008-12-01 00:00:00

abstract：:There are approximately 277,000 new cases of pancreatic cancer and 266,000 deaths from pancreatic cancer annually, indicating a mortality rate of 96% of the cases diagnosed. Because of the ineffectiveness of therapies, a major emphasis needs to be placed on prevention. This paper reviews the epidemiology and risk fact...

journal_title：Journal of gastroenterology and hepatology

authors： Pandol S,Gukovskaya A,Edderkaoui M,Dawson D,Eibl G,Lugea A

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal endoscopic submucosal dissection (ESD) is used for the treatment of large colorectal superficial neoplasms. However, there have been no large studies on electrocoagulation syndrome developing after colorectal ESD. The aim of this study was to clarify the incidence and clinical risk factors...

journal_title：Journal of gastroenterology and hepatology

authors： Ito S,Hotta K,Imai K,Yamaguchi Y,Kishida Y,Takizawa K,Kakushima N,Tanaka M,Kawata N,Yoshida M,Ishiwatari H,Matsubayashi H,Ono H

更新日期：2018-12-01 00:00:00

abstract：:The Asia-Pacific Expert Committee on Hepatitis B Management recently reviewed the impact of hepatitis B in the region and assessed the differences and similarities observed in the practical management of the disease in individual Asia-Pacific countries. Hepatitis B is a major health concern in the Asia-Pacific region,...

journal_title：Journal of gastroenterology and hepatology

authors： Mohamed R,Desmond P,Suh DJ,Amarapurkar D,Gane E,Guangbi Y,Hou JL,Jafri W,Lai CL,Lee CH,Lee SD,Lim SG,Guan R,Phiet PH,Piratvisuth T,Sollano J,Wu JC

更新日期：2004-09-01 00:00:00

abstract：:Extracorporeal liver assist devices have been used for more than five decades to support patients with liver failure. Numerous modifications have been made to both biological as well as mechanical liver assist devices. Possibly, an ideal liver assist device would be one that would perform optimal detoxification and sy...

journal_title：Journal of gastroenterology and hepatology

authors： Kapoor D

更新日期：2002-12-01 00:00:00

abstract：:Forty-six patients with primary biliary cirrhosis from a single centre were studied in a randomized placebo-controlled trial to determine the effectiveness of ursodeoxycholic acid (UDCA) over a 2 year period. The two groups were well-matched at baseline. For each parameter, by calculating the difference between the me...

journal_title：Journal of gastroenterology and hepatology

authors： Turner IB,Myszor M,Mitchison HC,Bennett MK,Burt AD,James OF

更新日期：1994-03-01 00:00:00

abstract：:Since receptor-binding cancer antigen expressed on SiSo cells (RCAS1) was first reported as a tumor-associated antigen of gynecologic cancer, its function and practical value as a tumor marker have been investigated in various types of carcinomas. Basic research has indicated that RCAS1 expression in cancer cells cont...

journal_title：Journal of gastroenterology and hepatology

authors： Enjoji M,Nakashima M,Yamaguchi K,Kotoh K,Nakamuta M

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:This study aimed to describe the clinical features, manometric findings, prevalence and incidence of achalasia in Singapore. METHODS:A total of 615 new patients referred for oesophageal manometry between 1989 and 1996 were examined prospectively. Twenty-four men and 25 women fulfilled the manometric and cli...

journal_title：Journal of gastroenterology and hepatology

authors： Ho KY,Tay HH,Kang JY

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND AND AIMS:A prospective, non-randomized cohort study on long-term lamivudine treatment, comparing efficacy, drug resistance, and prognosis for various stages of chronic hepatitis B virus (HBV)-related liver disease was performed to elucidate the significance and indication of lamivudine for individual patient...

journal_title：Journal of gastroenterology and hepatology

authors： Nishida T,Kobashi H,Fujioka S,Fujio K,Takaguchi K,Ikeda H,Kawaguchi M,Ando M,Araki Y,Higashi T,Shoji B,Takaki A,Iwasaki Y,Sakaguchi K,Shiratori Y,Yamamoto K

更新日期：2008-05-01 00:00:00

abstract：:A 22-year-old man visited our hospital (National Cancer Center Hospital East) complaining of fatigue and anorexia. A laboratory investigation demonstrated a biochemical 'picture' of obstructive jaundice. An abdominal CT showed a low density mass in the retropancreatic area with multiple enlarged periportal lymph nodes...

journal_title：Journal of gastroenterology and hepatology

authors： Miyamoto S,Furuse J,Maru Y,Tajiri H,Muto M,Yoshino M

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Microbial agents are a possible cause of ulcerative colitis. We have previously reported evidence of bacteria invading the colonic mucosa of patients with ulcerative colitis. We have isolated bacteria from inflamed colonic mucosa, examined the localization of the species in the mucosa, and assayed for serum ...

journal_title：Journal of gastroenterology and hepatology

authors： Ohkusa T,Sato N,Ogihara T,Morita K,Ogawa M,Okayasu I

更新日期：2002-08-01 00:00:00

abstract：:Although the incidence of bleeding from gastric varices is relatively low (10%-36%), the bleeding is massive once it has occurred and it increases the patient's mortality. The management of esophageal variceal bleeding is highly differentiated with several effective treatments available. In contrast, bleeding from gas...

journal_title：Journal of gastroenterology and hepatology

authors： Hashizume M,Akahoshi T,Tomikawa M

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIMS:A relatively large number of patients with multiple myeloma have been reported to develop a secondary malignancy such as cancer of the breast, biliary system or bowel. METHODS:A retrospective study was perfomed in 734 patients with hematologic disease diagnosed at Nippon Medical School Hospital bet...

journal_title：Journal of gastroenterology and hepatology

authors： Kishida T,Yonezawa M,Shibata Y,Tanaka S,Shinozawa I,Hoshino T,Tatsuguchi A,Feng L,Sato J,Fujimori S,Yoshida Y,Sakamoto C,Kobayashi M

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND AIM:Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease. Previous studies have investigated the association between dietary patterns and NAFLD, but their results are contradictory. Therefore, we carried out this meta-analysis to examine the association betw...

journal_title：Journal of gastroenterology and hepatology

authors： Hassani Zadeh S,Mansoori A,Hosseinzadeh M

更新日期：2020-12-02 00:00:00

abstract：:To evaluate the long-term efficacy and the timing of booster injection of a lyophilized, inactivated hepatitis A vaccine (HAV), we studied the acquired anti-hepatitis A virus titres in 45 subjects who received either two or three doses of the vaccine. With three doses > or = 0.5 microgram administered at 0, 1 and 6 mo...

journal_title：Journal of gastroenterology and hepatology

authors： Fujiyama S,Odoh K,Tanaka M,Kuramoto I,Tomita K

更新日期：1997-02-01 00:00:00

abstract：:We evaluated the clinical usefulness of a protein induced by vitamin K absence, antagonist-prothrombin (PIVKA-II), in detecting hepatocellular carcinoma (HCC) specifically in patients with liver cirrhosis, and the possible correlation between levels of PIVKA-II and pathological features of HCC. Plasma levels of PIVKA-...

journal_title：Journal of gastroenterology and hepatology

authors： Takikawa Y,Suzuki K,Yamazaki K,Goto T,Madarame T,Miura Y,Yoshida T,Kashiwabara T,Sato S

更新日期：1992-01-01 00:00:00

abstract：:Two intertwined compartments coexisting in nonpolypoid conventional (i.e. tubular or villous) adenomas are highlighted in this review: one built of dysplastic tissue on top and the other portraying crypts with irregular, corrupted shapes, albeit lined with normal epithelium, below. The latter compartment has remained ...

journal_title：Journal of gastroenterology and hepatology

authors： Rubio CA

更新日期：2020-08-05 00:00:00

abstract：BACKGROUND AND AIM:Results obtained from different hepatitis E virus (HEV) tests are usually inconsistent. The detection of serum HEV antigen (Ag) has been suggested to be more sensitive for the diagnosis of genotypes 1 and 3 HEV. METHODS:We compared the diagnostic accuracies of serum HEV Ag and HEV RNA by using 202 s...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang H,Rao H,Wang Y,Wang J,Kong X,Ji Y,Zhu L,Liu Y,Fang J,Yang M,Luo B,Wang Z,Shi Y,Wang Y,Wang H,Zhao J,Wei L

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Arterial vasodilatation, which is a major factor in the pathogenesis of the hyperkinetic circulatory state and portal hypertension in cirrhosis, is due to arterial nitric oxide (NO) overproduction secondary to endothelial NO synthase (eNOS) and inducible NOS (iNOS) upregulation. However, in cirrhosis, the re...

journal_title：Journal of gastroenterology and hepatology

authors： Malyshev E,Tazi KA,Moreau R,Lebrec D

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND AIM:The authors' previous report revealed that endothelin-1 might be released from B lymphocytes in cirrhotic patients with hypersplenism. Other investigators have shown that persistent exposure to environmental contaminants including arsenic might induce idiopathic portal hypertension. The aim of this s...

journal_title：Journal of gastroenterology and hepatology

authors： Yamaguchi E,Yamanoi A,Ono T,Nagasue N

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND AND AIM:Autoimmune hepatitis (AIH) is a chronic disease of unknown etiology, which usually progresses to cirrhosis if not diagnosed and treated promptly. Data on long-term follow up in children with AIH are scant. The aim of this study is to assess the long-term outcome of autoimmune hepatitis in children wi...

journal_title：Journal of gastroenterology and hepatology

authors： Saadah OI,Smith AL,Hardikar W

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:There are clinical reports that Helicobacter heilmannii, as well as Helicobacter pylori, has been clinically reported to cause gastric low-grade mucosa-associated lymphoid tissue-type (MALT) lymphoma, although its precise mechanism remains to be clarified. Thus, the present study was undertaken to elucidate ...

journal_title：Journal of gastroenterology and hepatology

authors： Nakamura M,Takahashi S,Matsui H,Murayama SY,Aikawa C,Sekiya Y,Nishikawa K,Matsumoto T,Yamada H,Tsuchimoto K

更新日期：2008-12-01 00:00:00

abstract：:Advances in technology have made possible the clinical application of magnetic resonance cholangiography, endoscopic, intra-operative and laparoscopic ultrasound in the study of the biliary tree, in addition to conventional magnetic resonance imaging and transabdominal ultrasound. The role of the conventional, as well...

journal_title：Journal of gastroenterology and hepatology

authors： Chan YL

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND AIM:In high or moderate risk populations, periodic surveillance of patients at risk of progression from gastric precursor lesions (PL) to gastric cancer (GC) is the most effective strategy for reducing the burden of GC. Incomplete type of intestinal metaplasia (IIM) may be considered as the best candidat...

journal_title：Journal of gastroenterology and hepatology

authors： González CA,Sanz-Anquela JM,Companioni O,Bonet C,Berdasco M,López C,Mendoza J,Martín-Arranz MD,Rey E,Poves E,Espinosa L,Barrio J,Torres MÁ,Cuatrecasas M,Elizalde I,Bujanda L,Garmendia M,Ferrández Á,Muñoz G,Andreu V

更新日期：2016-05-01 00:00:00