Plasma abnormal prothrombin (PIVKA-II): a new and reliable marker for the detection of hepatocellular carcinoma.

abstract：BACKGROUND:Several etiologic factors including hepatitis viruses, alcohol and aflatoxin have been implicated in the pathogenesis of hepatocellular carcinoma (HCC). There is, however, limited information from the Indian subcontinent. METHODS:Seventy-four consecutive cases of HCC were studied. A detailed history, tests ...

journal_title：Journal of gastroenterology and hepatology

authors： Sarin SK,Thakur V,Guptan RC,Saigal S,Malhotra V,Thyagarajan SP,Das BC

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND AND AIM:Oral mucosal pathologies are frequent in inflammatory bowel disease (IBD). Since host-microbiome interactions are implicated in the pathogenesis of IBD, in this study the potential for changes affecting the oral microbiome was evaluated using two complementary mouse models of colitis: either chemical...

journal_title：Journal of gastroenterology and hepatology

authors： Rautava J,Pinnell LJ,Vong L,Akseer N,Assa A,Sherman PM

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND AIM:The ability to detect early squamous neoplasia of the esophagus can be enhanced considerably by iodine staining during endoscopic examination; however, there has been no study on distinguishing high-grade intra-epithelial squamous neoplasia from low-grade dysplasia by endoscopic examination. We assum...

journal_title：Journal of gastroenterology and hepatology

authors： Shimizu Y,Omori T,Yokoyama A,Yoshida T,Hirota J,Ono Y,Yamamoto J,Kato M,Asaka M

更新日期：2008-04-01 00:00:00

abstract：:The mechanism of phagocytosis by Kupffer cells has been shown to be related to the Ca(2+)-calmodulin and the actomyosin systems. However the role of the transmembrane signal transmitter, G-protein, is still unknown. In this study, a quantitative evaluation of phagocytosis by Kupffer cells of rats in culture and the ef...

journal_title：Journal of gastroenterology and hepatology

authors： Hirose M,Watanabe S,Ueno T,Kitami N,Sato N

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND AND AIM:Whether an antiviral interferon (IFN)-based therapy (IBT) after curative treatment of hepatocellular carcinoma (HCC) improves the prognosis in patients with hepatitis C virus (HCV)-related HCC remains to be elucidated. METHODS:A total of 178 patients within the Milan criteria underwent curative trea...

journal_title：Journal of gastroenterology and hepatology

authors： Kanogawa N,Ogasawara S,Chiba T,Saito T,Motoyama T,Suzuki E,Ooka Y,Tawada A,Kanda T,Mikami S,Azemoto R,Kaiho T,Shinozaki M,Ohtsuka M,Miyazaki M,Yokosuka O

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The optimal management of acute Budd-Chiari syndrome (BCS) with liver failure is controversial. Options include anticoagulation, portal systemic shunting or liver transplantation. In recent years, transjugular intrahepatic portosystemic shunts (TIPS) have been tried in place of shunt surgery. We rep...

journal_title：Journal of gastroenterology and hepatology

authors： Kavanagh PM,Roberts J,Gibney R,Malone D,Hegarty J,McCormick PA

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Upper gastrointestinal endoscopy remains the gold standard for diagnosis of esophageal varices. Trans-abdominal ultrasound, as a noninvasive routine examination for the follow-up of cirrhosis patient, is safe, cheap, easy to perform, and plays an important role. In this study, we attempt to design a...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang CX,Xu JM,Li JB,Kong DR,Wang L,Xu XY,Zhao DM

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIM:Some patients with chronic hepatitis C experience virologic relapse even after achieving an end of treatment response. Prolonged therapy can be effective for helping such high-risk patients to avoid relapse. We aimed to identify factors predictive of virologic relapse in chronic hepatitis C patients ...

journal_title：Journal of gastroenterology and hepatology

authors： Shin SR,Sinn DH,Gwak GY,Choi MS,Lee JH,Koh KC,Yoo BC,Paik SW

更新日期：2010-05-01 00:00:00

abstract：:Sensitive and specific enzyme-linked immunosorbent assays (ELISA) were developed to detect separately the binding of polymerized human serum albumin (PHSA) to its antibody (A-PHSA) and to the hepatitis B surface antigen (HBsAg). A-PHSA was not detected in normal serum, whereas more than one-third to about half of sera...

journal_title：Journal of gastroenterology and hepatology

authors： Dash S,Panda SK,Nayak NC

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The objective of three-dimensional (3-D) endoscopic ultrasonography (EUS) is to recognize lesions stereoscopically. METHODS AND RESULTS:We investigated a total of 43 lesions in the upper gastrointestinal (GI) tract by regenerating 3-D images in eight cases of oesophageal cancer, two cases of oesophageal sub...

journal_title：Journal of gastroenterology and hepatology

authors： Tokiyama H,Yanai H,Nakamura H,Takeo Y,Yoshida T,Okita K

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND AIM:There is scanty data on the occurrence of celiac disease in patients with type 1 diabetes mellitus in South Asia. Our aim was to study the prevalence and clinical profile of celiac disease in patients with type 1 diabetes mellitus in a tertiary care referral centre in north India. METHODS:Consecutiv...

journal_title：Journal of gastroenterology and hepatology

authors： Bhadada SK,Kochhar R,Bhansali A,Dutta U,Kumar PR,Poornachandra KS,Vaiphei K,Nain CK,Singh K

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND AIM:This study examined the effects of adrenergic blockade on muscle wasting and expression of the ubiquitin-proteasome system, tumor necrosis factor-α (TNF-α) and its signaling pathways in skeletal muscles of cirrhotic rats. METHODS:Cirrhosis was induced by bile duct ligation in adult male Sprague-Dawl...

journal_title：Journal of gastroenterology and hepatology

authors： Lin SY,Wang YY,Chuang YH,Chen CJ

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND AIM:The goals of the study were to identify an effective treatment for ascites and to examine the influence of tolvaptan on outcomes by investigating non-responders to tolvaptan and comparing outcomes of hepatic cirrhosis in patients treated with and without tolvaptan. METHODS:In Study 1, of 145 patient...

journal_title：Journal of gastroenterology and hepatology

authors： Iwamoto T,Maeda M,Saeki I,Hidaka I,Tajima K,Ishikawa T,Takami T,Sakaida I

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence of Helicobacter pylori-negative and nonsteroidal anti-inflammatory drug-negative peptic ulcers, commonly known as idiopathic peptic ulcers (IPUs), has been reported to be very low (0.9-2.6%) in Japan based on data from the 1990s. However, recent trends have yet to be been reported. Her...

journal_title：Journal of gastroenterology and hepatology

authors： Kanno T,Iijima K,Abe Y,Yagi M,Asonuma S,Ohyauchi M,Ito H,Koike T,Shimosegawa T

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND AIM:Rejection of liver grafts is a difficult issue that has not been resolved. Preoperative replacement of liver cells in the graft with cells from the intended recipient may attenuate rejection. We investigated whether preoperative transplant of recipient bone marrow cells (BMCs) to the donor replaced l...

journal_title：Journal of gastroenterology and hepatology

authors： Endo K,Hori T,Jobara K,Hata T,Tsuruyama T,Uemoto S

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Depth of invasion beyond the muscularis propria (MP) by T3 rectal cancer can vary. The purpose of the present paper was to determine if depth of invasion beyond MP, as assessed by preoperative endoscopic ultrasound (EUS), can predict tumor recurrence in patients with T3 rectal tumors. METHODS:Patients with ...

journal_title：Journal of gastroenterology and hepatology

authors： Harewood GC,Kumar KS,Clain JE,Levy MJ,Nelson H

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVES:The epidemiology of lower gastrointestinal bleeding (LGIB) in Western populations has been reported; however, there are scant Asian reports. The aim of the present study was to determine the etiology of LGIB in a Chinese population by reporting a retrospective case series and a systematic analysis of Chinese...

journal_title：Journal of gastroenterology and hepatology

authors： Bai Y,Peng J,Gao J,Zou DW,Li ZS

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The objective of this study was to describe the prevalence of pathogenic microorganisms in asymptomatic individuals in a community study in Melbourne, Australia. METHODS:The study population was a subset of 2803 individuals participating in the Water Quality Study; a community based randomized tria...

journal_title：Journal of gastroenterology and hepatology

authors： Hellard ME,Sinclair MI,Hogg GG,Fairley CK

更新日期：2000-03-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the most commonly diagnosed malignancy of the liver and is the third most frequent cause of cancer death worldwide. Although advances in HCC detection and treatment have increased the likelihood of a cure at early stages of the disease, HCC remains largely incurable because of late pr...

journal_title：Journal of gastroenterology and hepatology

authors： Tong CM,Ma S,Guan XY

更新日期：2011-08-01 00:00:00

abstract：:It has been suggested that enalaprilat inhibits the renin-angiotensin-aldosterone system in plasma and tissue; it may therefore reduce portal vascular pressure owing to secondary hyperaldosteronism in patients with liver cirrhosis. In order to evaluate this concept, 20 patients with hepatitis B surface antigen (HBsAg)...

journal_title：Journal of gastroenterology and hepatology

authors： Chiang HT,Cheng JS,Lin M,Tseng WS,Chang JM,Lai KH

更新日期：1995-05-01 00:00:00

abstract：:The hepatitis C virus was first identified in 1989. It causes chronic hepatitis, cirrhosis and hepatocellular carcinoma. Global anti-HCV prevalence is 1-3%. Contaminated blood product, dirty needles and instruments, and injection drug use are the main parenteral routes of transmission. Cultural practices, such as acup...

journal_title：Journal of gastroenterology and hepatology

authors： Leung NW

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND AIM:Palliative endoscopic or percutaneous biliary drainage is used for unresectable advanced hilar cancer (HC). The best option for drainage in Bismuth type III or IV HC has not been established. The aims of this study are to identify factors predictive of endoscopic stenting failure and evaluate the eff...

journal_title：Journal of gastroenterology and hepatology

authors： Jang SI,Hwang JH,Lee KH,Yu JS,Kim HW,Yoon CJ,Lee YS,Paik KH,Lee SH,Lee DK

更新日期：2017-04-01 00:00:00

abstract：:Three clinicopathological phases of chronic hepatitis B virus (HBV) infection are identified. First, is immune tolerance of HBV. High levels of viraemia are associated with normal alanine aminotransferase (ALT) levels and minimal histological lesions. More than 30-40% of hepatocytes have the hepatitis B core antigen (...

journal_title：Journal of gastroenterology and hepatology

authors： Chu CM,Liaw YF

更新日期：1997-10-01 00:00:00

abstract：:Significant bile leak is an uncommon but serious complication of biliary tract surgery. Of twenty-five patients presenting with postoperative bile leak, 11 had complete tie-off of common bile duct and required surgery, while the remaining 14 had injury without complete obstruction and could be managed by endoscopic me...

journal_title：Journal of gastroenterology and hepatology

authors： Saraswat VA,Choudhuri G,Sharma BC,Agarwal DK,Gupta R,Baijal SS,Sikora SS,Saxena R,Kapoor VK

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND AIM:To validate an early discharge policy in patients admitted with upper gastrointestinal bleeding (UGIB) due to ulcers. METHODS:Patients with gastroduodenal ulcer or erosive gastritis/duodenitis were included in a previous study aiming to develop a practice guideline for early discharge of patients wi...

journal_title：Journal of gastroenterology and hepatology

authors： Chaparro M,Barbero A,Martín L,Esteban C,Espinosa L,de la Morena F,Sánchez A,Martín I,Santander C,Moreno-Otero R,Gisbert JP

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND & AIMS:Both medications with beta-blockers and isosorbide-5-mononitrate and endoscopic variceal ligation have been proven plausible in the prevention of variceal rebleeding. However, the relative efficacy and safety of the combined treatment for preventing rebleeding remains unresolved. METHODS:Patients wit...

journal_title：Journal of gastroenterology and hepatology

authors： Lo GH,Chen WC,Chan HH,Tsai WL,Hsu PI,Lin CK,Chen TA,Lai KH

更新日期：2009-06-01 00:00:00

abstract：:There is an increasing burden in digestive cancer in the coming years. With the advancement of endoscopic therapy, new molecular target therapy and minimally invasive ablation therapy, the treatment of digestive cancer will become more complicated. In Asia where gastric cancer and hepatocellular carcinoma are still pr...

journal_title：Journal of gastroenterology and hepatology

authors： Sung J

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND AIM:Chronic alcoholic liver disease is associated with hepatic insulin resistance, dysregulated lipid metabolism with increased toxic lipid (ceramide) accumulation, lipid peroxidation, and oxidative and endoplasmic reticulum (ER) stress. Peroxisome-proliferator activated receptor (PPAR) agonists are insu...

journal_title：Journal of gastroenterology and hepatology

authors： Ramirez T,Tong M,Chen WC,Nguyen QG,Wands JR,de la Monte SM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIM:Although regulatory T cells (Treg) and interleukin-17-producing CD4 T cells (Th17) have been demonstrated to play opposing roles in inflammation-associated diseases, their frequency and balance in different stages of hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF) remain unknown...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang GL,Xie DY,Lin BL,Xie C,Ye YN,Peng L,Zhang SQ,Zhang YF,Lai Q,Zhu JY,Zhang Y,Huang YS,Hu ZX,Gao ZL

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND AIM:Esophageal cancer is the second most common cancer among Indian males and is mostly associated with tobacco smoking and alcohol consumption. Epidermal growth factor receptor (EGFR) is a member of Type I tyrosine kinases. Its activation causes the docking of various proteins in its cytosolic tail. In ...

journal_title：Journal of gastroenterology and hepatology

authors： Parthasarathy S,Dhayaparan D,Jayanthi V,Devaraj SN,Devaraj H

更新日期：2011-02-01 00:00:00