Future role of gastroenterologists in digestive oncology in the Asia Pacific region: Panir Chelvam Memorial Lecture, Asian Pacific Digestive Week 2010.

abstract：BACKGROUND:Arterial vasodilatation, which is a major factor in the pathogenesis of the hyperkinetic circulatory state and portal hypertension in cirrhosis, is due to arterial nitric oxide (NO) overproduction secondary to endothelial NO synthase (eNOS) and inducible NOS (iNOS) upregulation. However, in cirrhosis, the re...

journal_title：Journal of gastroenterology and hepatology

authors： Malyshev E,Tazi KA,Moreau R,Lebrec D

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Oxidative stress plays an important role in the pathogenesis of chronic liver diseases. The plasma level of 8-isoprostane, a product of lipid peroxidation, is a marker of oxidative stress in vivo. The aim of the present study was to clarify whether the degree of lipid peroxidation, as measured by the plasma ...

journal_title：Journal of gastroenterology and hepatology

authors： Konishi M,Iwasa M,Araki J,Kobayashi Y,Katsuki A,Sumida Y,Nakagawa N,Kojima Y,Watanabe S,Adachi Y,Kaito M

更新日期：2006-12-01 00:00:00

abstract：:The incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade to become a global disease. The increasing number of studies on the incidence and course of IBD in East has enabled us to explore East versus West differences in the epidemiology of IBD which could enhance our understanding of th...

journal_title：Journal of gastroenterology and hepatology

authors： Mak WY,Zhao M,Ng SC,Burisch J

更新日期：2020-03-01 00:00:00

abstract：:Hepatitis C virus (HCV) is a member of the virus family Flaviviridae. At present HCV is classified into a discrete hepacivirus genus and is represented by six clades according to genome sequencing. Each clade is further divisible into subtypes, which may prove important for the study of clinical differences and epidem...

journal_title：Journal of gastroenterology and hepatology

authors： Howard CR

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Saccharomyces cerevisiae may contribute to the pathophysiology of Crohn's disease. We determined serum anti-Saccharomyces cerevisiae antibody (ASCA) levels in patients with inflammatory bowel disease. METHODS AND RESULTS:Immunoglobulin G (IgG) ASCA was measured by using an ELISA in serum samples from 19 pat...

journal_title：Journal of gastroenterology and hepatology

authors： Oshitani N,Hato F,Matsumoto T,Jinno Y,Sawa Y,Hara J,Nakamura S,Seki S,Arakawa T,Kitano A,Kitagawa S,Kuroki T

更新日期：2000-12-01 00:00:00

abstract：:The low Fermentable Oligosaccharides, Disaccharides, and Monosaccharides And Polyols (FODMAP) diet has been described, evaluated, and found efficacious for the treatment of patients with irritable bowel syndrome primarily in Western countries. The aim of this review was to address the applicability of this diet to Sou...

journal_title：Journal of gastroenterology and hepatology

authors： Hewawasam SP,Iacovou M,Muir JG,Gibson PR

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Studies of eradication of Helicobacter pylori and subsequent resolution of H. pylori-related gastritis, have focused mainly on medium and long-term change following eradication therapies. Results from those studies have shown that both acute and chronic inflammatory changes found in gastric mucosa eventually...

journal_title：Journal of gastroenterology and hepatology

authors： Chen W,Shu D,Wilson IR,Tie A,Chadwick VS

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND AIM:Hyperphosphatemia has been implicated in the development and treatment of various cancers. However, whether it can be used as a direct prognostic marker of colorectal cancer (CRC) has remained unexplored. Given new insights into the importance of hyperphosphatemia in CRC, we sought to evaluate the as...

journal_title：Journal of gastroenterology and hepatology

authors： Ye Z,Palazzo JP,Lin L,Lai Y,Guiles F,Myers RE,Han J,Xing J,Yang H

更新日期：2013-09-01 00:00:00

abstract：:To ascertain whether acid inhibition or Helicobacter pylori (HP) colonization is the decisive factor in the healing of duodenal ulcer, we treated 54 patients with famotidine and carried out long-term follow-up. Helicobacter pylori colonization was found in 70.4% of patients before treatment. There were no differences ...

journal_title：Journal of gastroenterology and hepatology

authors： Lai KH,Chang FY,Tsay SH,Lu LC,Cheng JT,Jeng SS,Wu TC,Ng WW,Jeng JS,Lee SD

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The CLOtest and other rapid urease detection kits are widely used in the endoscopic diagnosis of Helicobacter pylori. A new formulation CLOtest has been developed with the goal of obtaining a positive result more rapidly. The aims of this study were to validate the sensitivity and specificity of the...

journal_title：Journal of gastroenterology and hepatology

authors： Viiala CH,Windsor HM,Forbes GM,Chairman SO,Marshall BJ,Mollison LC

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:The purpose of the present paper was to determine informed consent practices for inpatient, open-access colonoscopy and endoscopic retrograde cholangiopancreatography (ERCP) at a tertiary referral center. METHODS:A two-part prospective study incorporating (i) an audit of consent practices for colonoscopy an...

journal_title：Journal of gastroenterology and hepatology

authors： Seow CH,Leber JM,Ee HC,Yusoff IF

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether the amount of Helicobacter pylori and the extent of gastric metaplasia in the duodenal mucosa play critical roles in the pathogenesis of duodenal ulcer. METHODS:Duodenal and gastric biopsy specimens were obtained from H. pylori-positive patients with duodenal u...

journal_title：Journal of gastroenterology and hepatology

authors： Futami H,Takashima M,Furuta T,Hanai H,Kaneko E

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND AND AIM:The major transporter responsible for bile acid uptake from the intestinal lumen is the apical sodium-dependent bile acid transporter (ASBT, SLC10A2). Analysis of the SLC10A2 gene has identified a variety of sequence variants including coding region single nucleotide polymorphisms (SNPs) that may inf...

journal_title：Journal of gastroenterology and hepatology

authors： Ho RH,Leake BF,Urquhart BL,Gregor JC,Dawson PA,Kim RB

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIM:The goals of the study were to identify an effective treatment for ascites and to examine the influence of tolvaptan on outcomes by investigating non-responders to tolvaptan and comparing outcomes of hepatic cirrhosis in patients treated with and without tolvaptan. METHODS:In Study 1, of 145 patient...

journal_title：Journal of gastroenterology and hepatology

authors： Iwamoto T,Maeda M,Saeki I,Hidaka I,Tajima K,Ishikawa T,Takami T,Sakaida I

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:There is scanty data on the occurrence of celiac disease in patients with type 1 diabetes mellitus in South Asia. Our aim was to study the prevalence and clinical profile of celiac disease in patients with type 1 diabetes mellitus in a tertiary care referral centre in north India. METHODS:Consecutiv...

journal_title：Journal of gastroenterology and hepatology

authors： Bhadada SK,Kochhar R,Bhansali A,Dutta U,Kumar PR,Poornachandra KS,Vaiphei K,Nain CK,Singh K

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND AND AIM:The aim of this study is to evaluate the association of the regulatory T cells (Treg)/T-helper (Th) 17 cells and transforming growth factor-β1 (TGF-β1)/interleukin-17 (IL-17) ratios with the survival and disease progression in patients with hepatitis B virus (HBV)-associated liver cirrhosis (LC). ME...

journal_title：Journal of gastroenterology and hepatology

authors： Yu X,Guo R,Ming D,Su M,Lin C,Deng Y,Lin Z,Su Z

更新日期：2014-05-01 00:00:00

abstract：:Despite steady progress in antiviral treatment for patients with chronic hepatitis C virus(HCV), many patients still have detectable serum HCV RNA levels by the end of interferon-based treatment and are known as virological non-responders. Re-treatment of these patients not responding to previous therapy remains chall...

journal_title：Journal of gastroenterology and hepatology

authors： Poo JL,Sánchez-Avila F,Kershenobich D,García-Samper X,Gongora J,Uribe M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Dysbiosis is thought to be relevant to the etiology and pathogenesis of Crohn's disease (CD). In this study, we investigated the abundance of Faecalibacterium prausnitzii, as well as Bilophila wadsworthia, in the gut microbiota of Japanese CD patients. METHODS:Forty-seven CD patients and 20 healthy...

journal_title：Journal of gastroenterology and hepatology

authors： Fujimoto T,Imaeda H,Takahashi K,Kasumi E,Bamba S,Fujiyama Y,Andoh A

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIM:Results obtained from different hepatitis E virus (HEV) tests are usually inconsistent. The detection of serum HEV antigen (Ag) has been suggested to be more sensitive for the diagnosis of genotypes 1 and 3 HEV. METHODS:We compared the diagnostic accuracies of serum HEV Ag and HEV RNA by using 202 s...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang H,Rao H,Wang Y,Wang J,Kong X,Ji Y,Zhu L,Liu Y,Fang J,Yang M,Luo B,Wang Z,Shi Y,Wang Y,Wang H,Zhao J,Wei L

更新日期：2019-02-01 00:00:00

abstract：:Acid-sensing pathways, which trigger mucosal defense mechanisms in response to luminal acid, involve the rapid afferent-mediated "capsaicin pathway" and the sustained "prostaglandin (PG) pathway." Luminal acid quickly increases protective PG synthesis and release from epithelia, although the mechanism by which luminal...

journal_title：Journal of gastroenterology and hepatology

authors： Akiba Y,Kaunitz JD

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic resection is feasible for superficial tumors in patients with ulcerative colitis; however, endoscopic resection options have not been evaluated comprehensively. We evaluated the efficacy and safety of endoscopic submucosal dissection and endoscopic mucosal resection, and decision making re...

journal_title：Journal of gastroenterology and hepatology

authors： Nishio M,Hirasawa K,Ozeki Y,Sawada A,Ikeda R,Fukuchi T,Kobayashi R,Makazu M,Sato C,Kunisaki R,Maeda S

更新日期：2020-08-04 00:00:00

abstract：:Despite a high prevalence of liver disease in Viet Nam, there has been no nationwide approach to the disease and no systematic screening of at-risk individuals. Risk factors include chronic hepatitis B (estimated prevalence of 12%), chronic hepatitis C (at least 2% prevalence), and heavy consumption of alcohol among m...

journal_title：Journal of gastroenterology and hepatology

authors： Gish RG,Bui TD,Nguyen CT,Nguyen DT,Tran HV,Tran DM,Trinh HN,International Group for Liver Health in Viet Nam.

更新日期：2012-02-01 00:00:00

abstract：AIMS:To investigate the relations between the formation of pigment gallstone and the function of the intestinal mucosal barrier, as well as the underlying mechanism. METHODS:Eighty guinea pigs were randomly divided into three groups in which they were respectively given normal diet, gallstone-causing diet, and gallsto...

journal_title：Journal of gastroenterology and hepatology

authors： Su Y,Wu S,Fan Y,Jin J,Zhang Z

更新日期：2009-08-01 00:00:00

abstract：:Significant bile leak is an uncommon but serious complication of biliary tract surgery. Of twenty-five patients presenting with postoperative bile leak, 11 had complete tie-off of common bile duct and required surgery, while the remaining 14 had injury without complete obstruction and could be managed by endoscopic me...

journal_title：Journal of gastroenterology and hepatology

authors： Saraswat VA,Choudhuri G,Sharma BC,Agarwal DK,Gupta R,Baijal SS,Sikora SS,Saxena R,Kapoor VK

更新日期：1996-02-01 00:00:00

abstract：:The effects of ethanol and its metabolites on collagen synthesis in cultured rat Ito cells and hepatocytes were studied. In cultured Ito cells, collagen synthetic ability reached peak values after incubation for 24 h and after 8 h in cultured hepatocytes. The distribution patterns of 14C-activity in each collagen frac...

journal_title：Journal of gastroenterology and hepatology

authors： Tsutsumi M,Takada A,Takase S,Shimanaka K,Enyama K

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND AIM:An endoscopic clip device was newly designed to accomplish the closure of large gastrointestinal defects. The aim of this study was to determine the feasibility and efficacy of this device in an ex vivo experimental setting. METHODS:This prospective study was conducted in porcine colons (n = 5). A l...

journal_title：Journal of gastroenterology and hepatology

authors： Wang ZJ,Li SY,Zhang YH,Chen Y,Zhang PP,Li ZS,Bai Y,Wang D

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIM:The risk of hepatocellular carcinoma (HCC) is known to be age dependent; the influence of age on prognosis is, however, controversial. The aim of this study was to compare the tumor characteristics and survival rates of young and old HCC patients, with respect to tumor stage. METHODS:We reviewed the...

journal_title：Journal of gastroenterology and hepatology

authors： Cho SJ,Yoon JH,Hwang SS,Lee HS

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND AIM:Bacterial infections are among the main causes of death in patients with cirrhosis. While there are unquestionable benefits of using albumin in patients with spontaneous bacterial peritonitis, the benefits of albumin are controversial for those with extraperitoneal infections. The aim was to compare ...

journal_title：Journal of gastroenterology and hepatology

authors： Leão GS,John Neto G,Jotz RF,Mattos AA,Mattos ÂZ

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIM:Since the advent of direct-acting antiviral (DAA) therapy, the total eradication of hepatitis C virus has been achievable with the recovery of hepatic reserve after achievement of sustained virologic response (SVR). Hence, here, we examined the factors affecting the recovery of hepatic reserve. METH...

journal_title：Journal of gastroenterology and hepatology

authors： Nakajima T,Karino Y,Hige S,Suii H,Tatsumi R,Yamaguchi M,Arakawa T,Kuwata Y,Hasegawa T,Toyota J

更新日期：2020-09-29 00:00:00

abstract：:Humans and Helicobacter pylori have evolved and adapted over tens of thousands of years. Yet peptic ulcer disease appeared to be rare prior to the 19th century. The prevalence of peptic ulcer disease increased between 1850 and 1900 and culminated in a cohort at high risk that was born at the end of the 19th century. T...

journal_title：Journal of gastroenterology and hepatology

authors： Roberts-Thomson IC

更新日期：2018-07-01 00:00:00