A two year controlled trial examining the effectiveness of ursodeoxycholic acid in primary biliary cirrhosis.

abstract：BACKGROUND AND AIM:We elucidated the clinical significance of distal contractile integral-to-esophageal impedance integral (EII) ratio (DCIIR) in ineffective esophageal motility (IEM) adult patients. METHODS:We recruited 101 patients with IEM (48.38 ± 1.58 years) and 42 matched healthy volunteers (44.28 ± 1.85 years) ...

journal_title：Journal of gastroenterology and hepatology

authors： Wu JF,Tsai IJ,Tong TW,Lin YC,Yang CH,Tseng PH

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The binucleation of hepatocytes, which was known as an important feature of liver growth and physiology, has been reported to be increased during the chronic oxidative injury stage and has been regarded as an age-related change of hepatic structures. Therefore, we investigated the binuclearity patte...

journal_title：Journal of gastroenterology and hepatology

authors： Park JK,Hong IH,Ki MR,Chung HY,Ishigami A,Ji AR,Goo MJ,Kim DH,Kwak JH,Min CW,Lee SS,Jeong KS

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND AND AIM:Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease. Previous studies have investigated the association between dietary patterns and NAFLD, but their results are contradictory. Therefore, we carried out this meta-analysis to examine the association betw...

journal_title：Journal of gastroenterology and hepatology

authors： Hassani Zadeh S,Mansoori A,Hosseinzadeh M

更新日期：2020-12-02 00:00:00

abstract：:In order to identify proguanylin-secreting cells, we have raised an antiserum against the synthetic fragment of human proguanylin (1-15) and have examined the proguanylin-positive cells in the human and rat gastrointestinal tract by immunohistochemical methods. Numerous proguanylin (1-15)-immunoreactive cells were fou...

journal_title：Journal of gastroenterology and hepatology

authors： Ieda H,Naruse S,Furuya S,Ozaki T,Ando E,Nokihara K,Hori S,Kitagawa M,Hayakawa T

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND AND AIM:The risk of hepatocellular carcinoma (HCC) is known to be age dependent; the influence of age on prognosis is, however, controversial. The aim of this study was to compare the tumor characteristics and survival rates of young and old HCC patients, with respect to tumor stage. METHODS:We reviewed the...

journal_title：Journal of gastroenterology and hepatology

authors： Cho SJ,Yoon JH,Hwang SS,Lee HS

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND AIMS:There is a paucity of literature regarding the clinical profile of chronic pancreatitis (CP) in children. The aims of this retrospective study were to determine the etiology and clinical presentation, and to present our experience in diagnosing CP in children in China. METHODS:Clinical data of chil...

journal_title：Journal of gastroenterology and hepatology

authors： Wang W,Liao Z,Li ZS,Shi XG,Wang LW,Liu F,Wu RP,Zheng JM

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND AND AIM:Symptoms and complications of primary biliary cirrhosis (PBC) have been shown to impair patients' health-related quality of life (HRQOL) in the West. We aimed to measure the HRQOL and to determine the factors associated with worse HRQOL among the Chinese PBC patients in Hong Kong. METHODS:Chinese pa...

journal_title：Journal of gastroenterology and hepatology

authors： Wong GL,Law FM,Wong VW,Hui AY,Chan FK,Sung JJ,Chan HL

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND AND AIM:Development of hepatic cirrhosis involves oxidative stress, inflammation, hepatic stellate cells (HSC)s activation and fibrosis. On the other hand, quercetin, a natural flavonoid is a potent antioxidant and activator of superoxide dismutase and catalase. The aim was to determinate the effect of querc...

journal_title：Journal of gastroenterology and hepatology

authors： Hernández-Ortega LD,Alcántar-Díaz BE,Ruiz-Corro LA,Sandoval-Rodriguez A,Bueno-Topete M,Armendariz-Borunda J,Salazar-Montes AM

更新日期：2012-12-01 00:00:00

abstract：:Cell proliferation in the gastroduodenal mucosa of patients with duodenal ulcers was evaluated using flow cytometry. Forty patients with duodenal ulcers and 12 normal subjects were investigated. Biopsy samples were obtained during endoscopic examination and subjected to DNA analysis by flow cytometry. Thirty patients ...

journal_title：Journal of gastroenterology and hepatology

authors： Kobayashi I,Kawano S,Tsuji S,Nakama A,Sawaoka H,Masuda E,Nagano K,Fusamoto H,Kamada T

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND AND AIMS:We identified patients with nonalcoholic fatty liver disease (NAFLD) to determine the predictive value of serum markers to diagnose histological steatohepatitis (NASH). METHODS:Demographic, serological, radiological and histological variables on 95 consecutive patients with NAFLD were recorded. The...

journal_title：Journal of gastroenterology and hepatology

authors： Malik R,Chang M,Bhaskar K,Nasser I,Curry M,Schuppan D,Byrnes V,Afdhal N

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Toll-like receptors (TLRs) are involved in innate immunity. Certain viruses interact with TLRs and mediate antiviral effects as well as immune responses. The aim of this study was to investigate the effect of TLRs on pathogenesis in hepatitis C virus (HCV)-infected patients. METHODS:Peripheral blood mononuc...

journal_title：Journal of gastroenterology and hepatology

authors： Sato K,Ishikawa T,Okumura A,Yamauchi T,Sato S,Ayada M,Matsumoto E,Hotta N,Oohashi T,Fukuzawa Y,Kakumu S

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND AIM:Although rabeprazole (RPZ), a proton pump inhibitor, has been reported to have a bactericidal effect on Helicobacter pylori (H. pylori), no studies have been conducted regarding the effect of RPZ on gastric mucosal lesion formation caused by this bacterium. In the present study, we investigated the e...

journal_title：Journal of gastroenterology and hepatology

authors： Suzuki H,Miyazawa M,Nagahashi S,Sato M,Bessho M,Nagata H,Miura S,Ishii H

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND AND AIM:The major transporter responsible for bile acid uptake from the intestinal lumen is the apical sodium-dependent bile acid transporter (ASBT, SLC10A2). Analysis of the SLC10A2 gene has identified a variety of sequence variants including coding region single nucleotide polymorphisms (SNPs) that may inf...

journal_title：Journal of gastroenterology and hepatology

authors： Ho RH,Leake BF,Urquhart BL,Gregor JC,Dawson PA,Kim RB

更新日期：2011-12-01 00:00:00

abstract：:This study examined Na+/H+ ion exchange of caecal and colonic mucus. Two distinct Na+/H+ ion exchange populations of caecal mucus were identified, one group being a cation exchanger and the other an anion exchanger, suggesting that caecal mucus has ampholyte properties responsive to changing physical and chemical prop...

journal_title：Journal of gastroenterology and hepatology

authors： Duncan CE,Tasman-Jones C

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND AIM:Exogenous 8-hydroxydeoxyguanosine (8-OHdG) was suggested as an inhibitor of Rac1 and NADPH oxidase (NOX). The aim of this study was to evaluate the effects of the exogenous 8-OHdG on hepatic fibrogenesis in vitro and in vivo model of liver fibrosis. METHODS:Adult Sprague-Dawley rats were allocated t...

journal_title：Journal of gastroenterology and hepatology

authors： Shin SK,Kim KO,Kim SH,Kwon OS,Choi CS,Jeong SH,Kim YS,Kim JH,Chung MH

更新日期：2020-06-01 00:00:00

abstract：:We have previously established a cell damage model, with damage induced by either acid or pepsin treatment for 30 min, involving a rat gastric epithelial cell line (RGM1). In the present study, pretreatment of cells with epidermal growth factor (EGF; 0.1-10 ng/mL) or sucralfate (0.1-3 mg/mL) for 4 h prevented such cel...

journal_title：Journal of gastroenterology and hepatology

authors： Furukawa O,Okabe S

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND AIM:Differentially expressed (DE) genes detected at the population-level through case-control comparison provide no information on the dysregulation frequencies of DE genes in a cancer. In this work, we aimed to identify the genes with universally upregulated or downregulated expressions in colorectal ca...

journal_title：Journal of gastroenterology and hepatology

authors： Song K,Su W,Liu Y,Zhang J,Liang Q,Li N,Guan Q,He J,Bai X,Zhao W,Guo Z

更新日期：2019-05-01 00:00:00

abstract：:Following the development of tests for hepatitis C virus and hepatitis E virus infection, it became clear that there remained cases of hepatitis that were non-A-E. Such cases provided impetus for the search for additional hepatitis viruses and, by using molecular techniques, several candidates were identified. An ente...

journal_title：Journal of gastroenterology and hepatology

authors： Bowden S

更新日期：2001-02-01 00:00:00

abstract：:Helicobacter pylori, non-steroidal anti-inflammatory drugs, family history, blood group O, hyperpepsinogenaemia A, alcohol and smoking have been reported to be risk factors for peptic ulcer disease. The strength of causal risk factors may differ in different populations. In 215 Japanese and 493 Dutch employees of simi...

journal_title：Journal of gastroenterology and hepatology

authors： Schlemper RJ,van der Werf SD,Vandenbroucke JP,Biemond I,Lamers CB

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND AIM:Interleukin (IL)-18 level and association of its two promoter gene polymorphisms at -607 C/A and -137 G/C positions were investigated in Iranian patients with gastrointestinal (GI) cancers. METHODS:232 cases of GI cancers and 312 healthy controls were enrolled. Serum level of IL-18 was measured by e...

journal_title：Journal of gastroenterology and hepatology

authors： Haghshenas MR,Hosseini SV,Mahmoudi M,Saberi-Firozi M,Farjadian S,Ghaderi A

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The role of Helicobacter pylori infection in gastroduodenal lesions might be different between the general population and AIDS patients. The aim of the present study was to compare the prevalence of H. pylori and cytomegalovirus (CMV) infection in AIDS patients and HIV-negative controls. The impact ...

journal_title：Journal of gastroenterology and hepatology

authors： Chiu HM,Wu MS,Hung CC,Shun CT,Lin JT

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:The clinicopathological profiles and outcome of chronic hepatitis B can differ by hepatitis B virus (HBV) genotypes. In Japan, genotype B and C are two major HBV genotypes. The basic core promoter and precore mutations are other known viral factors for disease activity, although the relationship between HBV ...

journal_title：Journal of gastroenterology and hepatology

authors： Watanabe K,Takahashi T,Takahashi S,Okoshi S,Ichida T,Aoyagi Y

更新日期：2005-03-01 00:00:00

abstract：:Maintaining high levels of intracellular cyclic AMP (cAMP) is known to inhibit the growth of various proliferating cells including hepatocytes. We show here that transient (30 min) elevations of cAMP induced by addition of 8-bromo-cAMP (1 mmol/L) to rat hepatocytes in primary culture at three time points (12 h, 16 h a...

journal_title：Journal of gastroenterology and hepatology

authors： Kikukawa M,Okamoto Y,Nakano H

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Endoscopic ultrasonography (EUS) is a useful tool for the evaluation of gastric wall infiltration including gastric lymphoma. The aims of this study were to characterize gastric low-grade mucosa-associated lymphoid tissue (MALT) lymphoma according to EUS findings and to evaluate the role of a miniat...

journal_title：Journal of gastroenterology and hepatology

authors： Yeh HZ,Chen GH,Chang WD,Poon SK,Yang SS,Lien HC,Chang CS,Chou G

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:The purpose of the present paper was to investigate dendritic cell (DC) and T-cell functions in patients with chronic hepatitis B (CHB) and determine whether therapeutic DC vaccines could restore T-cell function in those patients in vitro. METHODS:Twelve patients with CHB and 10 normal control subjects with...

journal_title：Journal of gastroenterology and hepatology

authors： Duan XZ,He HX,Zhuang H

更新日期：2006-06-01 00:00:00

abstract：:Primary liver cancer, particularly hepatocellular carcinoma (HCC) remains a significant disease worldwide. It is among the top three causes of cancer death in the Asia Pacific region because of the high prevalence of its main etiological agents, chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. I...

journal_title：Journal of gastroenterology and hepatology

authors： Yuen MF,Hou JL,Chutaputti A,Asia Pacific Working Party on Prevention of Hepatocellular Carcinoma.

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND AIM:The aim of the study was to develop a method of quantitation of endoscopic ultrasonography (EUS) changes of chronic pancreatitis (CP). METHODS:Twenty-three patients with chronic pancreatitis by EUS were compared with nine normal subjects. Hyperechogenicity was evaluated as the size of the hyperechoi...

journal_title：Journal of gastroenterology and hepatology

authors： Irisawa A,Mishra G,Hernandez LV,Bhutani MS

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:With the prevalence of Helicobacter pylori (H. pylori) infection rapidly decreasing in Japan, endoscopic findings and dyspeptic symptoms need to be re-evaluated. METHODS:In a health check-up program, endoscopy was performed on 530 young Japanese subjects (371 men and 159 women) born in the 1970s. Helicobact...

journal_title：Journal of gastroenterology and hepatology

authors： Shimatani T,Inoue M,Iwamoto K,Hyogo H,Yokozaki M,Saeki T,Tazuma S,Horikawa Y

更新日期：2005-09-01 00:00:00

abstract：:Between 1988 and 1992 ultrasound-guided fine needle aspiration biopsies of thromboses in the main branches of the portal vein were carried out in 15 patients with liver cirrhosis. The aims of the study were to evaluate the usefulness, feasibility and diagnostic accuracy of this procedure in cirrhotics with known or su...

journal_title：Journal of gastroenterology and hepatology

authors： De Sio I,Castellano L,Calandra M,Romano M,Persico M,Del Vecchio-Blanco C

更新日期：1995-11-01 00:00:00

abstract：:The purpose of tumour staging for colorectal cancer (CRC) is to help define clinical management, facilitate communication between physicians, provide a basis for stratification and analysis of treatment results in prospective studies, and provide some prognostic information for patients and their families. The World C...

journal_title：Journal of gastroenterology and hepatology

authors： Fielding LP,Arsenault PA,Chapuis PH,Dent O,Gathright B,Hardcastle JD,Hermanek P,Jass JR,Newland RC

更新日期：1991-07-01 00:00:00