Experimental investigation of the role of endothelin-1 in idiopathic portal hypertension.

abstract：BACKGROUND AND AIMS:The optimal management of acute Budd-Chiari syndrome (BCS) with liver failure is controversial. Options include anticoagulation, portal systemic shunting or liver transplantation. In recent years, transjugular intrahepatic portosystemic shunts (TIPS) have been tried in place of shunt surgery. We rep...

journal_title：Journal of gastroenterology and hepatology

authors： Kavanagh PM,Roberts J,Gibney R,Malone D,Hegarty J,McCormick PA

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND AND AIM:Based on our previous studies that Artemisia asiatica extracts exert either antioxidative or cytoprotective actions against non-steroidal anti-inflammatory drugs or Helicobacter pylori-induced gastric mucosal injury, or imposes qualified ulcer healing in an acetic acid-induced gastric ulcer model, we...

journal_title：Journal of gastroenterology and hepatology

authors： Park SW,Oh TY,Kim YS,Sim H,Park SJ,Jang EJ,Park JS,Baik HW,Hahm KB

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Hypothyroidism is commonly thought to cause decreased gastric emptying but is mostly associated with autoimmune disease. In the present study the gastric emptying function of thyroid cancer patients with severe hypothyroidism of short duration was evaluated with a radionuclide solid meal gastric emptying stu...

journal_title：Journal of gastroenterology and hepatology

authors： Kao PF,Lin JD,Chiu CT,Hsu HT,See LC,Tzen KY

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND AND AIM:Although regulatory T cells (Treg) and interleukin-17-producing CD4 T cells (Th17) have been demonstrated to play opposing roles in inflammation-associated diseases, their frequency and balance in different stages of hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACLF) remain unknown...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang GL,Xie DY,Lin BL,Xie C,Ye YN,Peng L,Zhang SQ,Zhang YF,Lai Q,Zhu JY,Zhang Y,Huang YS,Hu ZX,Gao ZL

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND AND AIM:The present study aimed to evaluate the non-inferiority of low-volume oral sulfate solution (OSS) to 4-L polyethylene glycol (PEG) solutions administered in a split-dose regimen as bowel preparation for colonoscopy. The safety and tolerability were also compared between the two regimens. METHODS:In ...

journal_title：Journal of gastroenterology and hepatology

authors： Yang HJ,Park SK,Kim JH,Im JP,Yeom DH,Seo GS,Park DI

更新日期：2017-01-01 00:00:00

abstract：:Iatrogenic superior mesenteric arteriovenous fistula is rare. We treated a patient with this problem 6 years after small bowel resection for intestinal obstruction. The symptoms and signs were those of intestinal ischaemia and portal hypertension with an abdominal bruit. Ultrasonography and enhanced computerized tomog...

journal_title：Journal of gastroenterology and hepatology

authors： Iwai M,Kashiwadani M,Suyama Y,Miyoshi M,Kashima K

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether the amount of Helicobacter pylori and the extent of gastric metaplasia in the duodenal mucosa play critical roles in the pathogenesis of duodenal ulcer. METHODS:Duodenal and gastric biopsy specimens were obtained from H. pylori-positive patients with duodenal u...

journal_title：Journal of gastroenterology and hepatology

authors： Futami H,Takashima M,Furuta T,Hanai H,Kaneko E

更新日期：1999-02-01 00:00:00

abstract：:The aetiology of idiopathic portal hypertension or hepatoportal sclerosis is unknown. In view of the indirect evidence for underlying immunologic abnormalities 14 patients (all middle-aged females) were studied. Various auto-antibodies were demonstrated in seven patients and high levels of serum immunoglobulins, eithe...

journal_title：Journal of gastroenterology and hepatology

authors： Tokushige K,Komatsu T,Ohzu K,Yamauchi K,Obata H

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND AND AIM:Abdominal wall hernia is a common feature of decompensated liver cirrhosis and frequently causes life-threatening complications or severe pain. However, there have been no data reported on postoperative mortality, hepatic functional deterioration and recurrence rate according to Child-Turcotte-Pugh (...

journal_title：Journal of gastroenterology and hepatology

authors： Park JK,Lee SH,Yoon WJ,Lee JK,Park SC,Park BJ,Jung YJ,Kim BG,Yoon JH,Kim CY,Ha J,Park KJ,Kim YJ

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic screening for esophageal varices (EVs) is expensive and invasive. Besides traditional noninvasive markers, we explore additional candidate markers including portal hypertension serum marker-soluble CD136 (sCD163) and genetic variants of splanchnic vasodilatation and revascularization pathw...

journal_title：Journal of gastroenterology and hepatology

authors： Yang YY,Hou MC,Lin MW,Chen PH,Liao WC,Chu CJ,Lin HC

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:The aim of the present study was to determine whether rats with moderately fatty liver could withstand a 90% hepatectomy, which rats with normal livers can survive. MATERIAL AND METHODS:Nine-week-old male Wistar rats were used. Normal rat chow was fed to the normal liver group, and fat-enriched rat chow w...

journal_title：Journal of gastroenterology and hepatology

authors： Morioka D,Watanabe K,Makino H,Saito S,Ueda M,Kubota T,Sekido H,Matsuo K,Ichikawa Y,Endo I,Togo S,Shimada H

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND AIM:This study investigated the usefulness of near-focus narrowband imaging (NF-NBI) for determining gastric tumor margins compared with indigo carmine chromoendoscopy (ICC) before endoscopic submucosal dissection (ESD). METHODS:This prospective randomized controlled trial was conducted at seven teachin...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JW,Jung Y,Jang JY,Kim GH,Bang BW,Park JC,Choi HS,Cho JH,Research Group for Endoscopic Instruments and Stents of Korean Society of Gastrointestinal Endoscopy.

更新日期：2020-11-01 00:00:00

abstract：AIM:To investigate the morphological changes of intratumoral microvessels after administration of thalidomide in occult hepatic metastases. METHODS:Twenty mice with hepatic metastases created by injection of colon-26 tumor cells into the spleen were enrolled. Ten mice were treated with thalidomide (200 mg/kg) by intra...

journal_title：Journal of gastroenterology and hepatology

authors： Liu Y,Li H,Matsui O

更新日期：2009-06-01 00:00:00

abstract：:The identification of activated hepatic stellate cells and related cell types as key fibrogenic effectors during liver injury has led to intense evaluation of transcriptional events underlying their behavior. While initial studies focused on characterizing interactions between transcription factors and regulatory regi...

journal_title：Journal of gastroenterology and hepatology

authors： Friedman SL

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatorenal syndrome (HRS) occurs in patients with advanced liver cirrhosis and has a poor outcome. The aim of the present study was to investigate which patients with HRS are likely to benefit from hemodialysis. METHODS:Data were collected prospectively from 30 patients with Child-Pugh C liver cirr...

journal_title：Journal of gastroenterology and hepatology

authors： Witzke O,Baumann M,Patschan D,Patschan S,Mitchell A,Treichel U,Gerken G,Philipp T,Kribben A

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Cancer invasion and metastasis are critical events for patient prognosis; however, the most important step in the whole process of lymph node (LN) metastasis in gastric cancer remains obscure. In this study, the significance of cancer cell behaviors, such as cell detachment, stromal invasion and lym...

journal_title：Journal of gastroenterology and hepatology

authors： Kamata I,Ishikawa Y,Akishima-Fukasawa Y,Ito K,Akasaka Y,Uzuki M,Fujimoto A,Morita H,Tamai S,Maehara T,Ogata K,Shimokawa R,Igarashi Y,Miki K,Ishii T

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis E virus (HEV) infection is endemic in several developing countries. Clinical manifestations of this infection vary widely from asymptomatic infection to uncomplicated acute viral hepatitis and fulminant hepatic failure. The pathogenesis of this disease and the reason of varying disease seve...

journal_title：Journal of gastroenterology and hepatology

authors： Srivastava R,Aggarwal R,Sachdeva S,Alam MI,Jameel S,Naik S

更新日期：2011-02-01 00:00:00

abstract：AIM:To evaluate the characterization of liver hemangiomas and malignant tumors using power Doppler sonography before and after intravenous injection of a sonocontrast agent. METHODS:Forty-five patients with 57 liver tumors (22 hemangiomas, 24 metastases, 10 hepatocellular carcinomas (HCC) and one cholangiocellular car...

journal_title：Journal of gastroenterology and hepatology

authors： Karabacakoglu A,Karakose S,Cil AS,Kaya A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The CLOtest and other rapid urease detection kits are widely used in the endoscopic diagnosis of Helicobacter pylori. A new formulation CLOtest has been developed with the goal of obtaining a positive result more rapidly. The aims of this study were to validate the sensitivity and specificity of the...

journal_title：Journal of gastroenterology and hepatology

authors： Viiala CH,Windsor HM,Forbes GM,Chairman SO,Marshall BJ,Mollison LC

更新日期：2002-02-01 00:00:00

abstract：:This article highlights the importance of hepatotropic viruses as pathogens in patients undergoing transplantation, their contribution to morbidity and mortality after transplantation and the approach to treatment of these pathogens when they cause disease. Although many advances have been made in the management of vi...

journal_title：Journal of gastroenterology and hepatology

authors： Bzowej NH,Wright TL

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND AIM:HFE mutations, a common cause of hereditary hemochromatosis (HH), are reportedly associated with hepatic iron overload, severe liver fibrosis, and good response to interferon treatment in European patients with chronic hepatitis C (CHC). HH shows ethnicity-based differences and little is known about ...

journal_title：Journal of gastroenterology and hepatology

authors： Ishizu Y,Katano Y,Honda T,Hayashi K,Ishigami M,Itoh A,Hirooka Y,Nakano I,Goto H

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND AND AIMS:According to reports in Japanese patients, 1 week of Helicobacter pylori eradication therapy alone is not adequate for healing of gastric ulcers; 7-8 weeks of anti-ulcer therapy are subsequently required. We compared a gastroprotective drug, sofalcone, and an H(2)-receptor antagonist, cimetidine, in...

journal_title：Journal of gastroenterology and hepatology

authors： Higuchi K,Watanabe T,Tanigawa T,Tominaga K,Fujiwara Y,Arakawa T

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND AIM:We aimed to determine whether reflux- and symptom-related parameters can predict the efficacy of proton pump inhibitors (PPI) in non-erosive reflux disease (NERD). METHODS:Twenty-seven NERD patients who had experienced heartburn more than once a week within the previous month were enrolled. Intraeso...

journal_title：Journal of gastroenterology and hepatology

authors： Shimatani T,Sugimoto M,Nishino M,Adachi K,Furuta K,Ito M,Kurosawa S,Manabe N,Mannen K,Hongo M,Chiba T,Kinoshita Y,Acid-Related Symptom Research (ARS) Group.

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Treatment of post-transplantation recurrence of hepatitis B virus (HBV) infection despite prophylaxis with hepatitis B immunoglobulin (HBIG) and lamivudine combination therapy is not easy. Because HBV reinfection has a severe course and could result in graft failure in liver transplant recipients, prompt med...

journal_title：Journal of gastroenterology and hepatology

authors： Akyildiz M,Karasu Z,Zeytunlu M,Aydin U,Ozacar T,Kilic M

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Colorectal laterally spreading tumors (LST) > 20 mm are usually treated by endoscopic submucosal dissection (ESD) or endoscopic mucosal resection (EMR). Endoscopic piecemeal mucosal resection (EPMR) is sometimes required. The aim of our study was to compare the outcomes of ESD and EMR, including EPM...

journal_title：Journal of gastroenterology and hepatology

authors： Terasaki M,Tanaka S,Oka S,Nakadoi K,Takata S,Kanao H,Yoshida S,Chayama K

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Nicotine administration is known to decrease lower oesophageal sphincter (LOS) pressure. Although a few studies have assessed the effect of tobacco on the LOS, the effect of acute and long-term oral tobacco use on oesophageal motility is not known. The study was designed to investigate the effect of...

journal_title：Journal of gastroenterology and hepatology

authors： Bhandarkar PV,Shah SK,Meshram M,Abraham P,Narayanan TS,Bhatia SJ

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND AND AIM:T-cell activation, mediated by the interaction with major histocompatibility complex (MHC)-peptide complexes and B7 costimulatory molecules on antigen-presenting cells, is an essential event in the pathogenesis of inflammatory bowel disease (IBD). We investigated the expression of B7 costimulatory mo...

journal_title：Journal of gastroenterology and hepatology

authors： Grose RH,Howarth GS,Xian CJ,Hohmann AW

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The (13)C-urea breath test ((13)C-UBT) is a reliable non-invasive method of diagnosing Helicobacter pylori infection in adults and children. However, only a few validation studies have been performed on the (13)C-UBT in very young children. The purpose of the present study was to evaluate the diagno...

journal_title：Journal of gastroenterology and hepatology

authors： Yang HR,Seo JK

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Liver biopsy is the gold standard test to determine the grade of fibrosis, but there are associated problems. Because gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid is secreted partially in hepatocytes and bile, it is possible that ethoxybenzyl-magnetic resonance imaging (EOB-MRI) corre...

journal_title：Journal of gastroenterology and hepatology

authors： Nojiri S,Kusakabe A,Fujiwara K,Shinkai N,Matsuura K,Iio E,Miyaki T,Joh T

更新日期：2013-06-01 00:00:00

abstract：:The effects of camostat mesilate, a synthetic serine protease inhibitor on gastric microcirculation and active oxygen species generated by leucocytes from the gastric and jugular veins in the early period after thermal injury were assessed. Male Wistar rats were anaesthetized and a 30% full skin-thickness dorsal burn ...

journal_title：Journal of gastroenterology and hepatology

authors： Yoshida M,Wakabayashi G,Ishikawa H,Otani Y,Shimazu M,Kubota T,Kumal K,Kurose I,Miura S,Ishii H,Kitajima M

更新日期：1998-01-01 00:00:00