Adaptive immune responses during acute uncomplicated and fulminant hepatitis E.

abstract：:Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in Western industrialized countries, affecting 20-40% of the general population. Large population-based surveys in China, Japan, and Korea indicate that the prevalence of NAFLD is now 12% to 24% in population subgroups, depending on age, gende...

journal_title：Journal of gastroenterology and hepatology

authors： Chitturi S,Farrell GC,Hashimoto E,Saibara T,Lau GK,Sollano JD,Asia-Pacific Working Party on NAFLD.

更新日期：2007-06-01 00:00:00

abstract：:The polymerase chain reaction (PCR) was used to examine expression of interferon-alpha (IFN A) genes in general and the expression of messenger RNA (mRNA) encoding the subtypes IFN-alpha-2 and IFN-alpha-4 in blood and liver biopsy samples from patients with chronic hepatitis C or hepatitis non-A, non-B (HC/HNANB) infe...

journal_title：Journal of gastroenterology and hepatology

authors： Brandt ER,Devenish RJ,Hertzog PJ,Dudley FJ,Linnane AW

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatic fibrosis is a worldwide healthy burden associated with significant morbidity and mortality. It is caused by a variety of chronic liver injuries. There is currently no effective treatment for liver fibrosis. In this report, we tested an imidazolium salt, 1,3-diisopropylimidazolium tetrafluorob...

journal_title：Journal of gastroenterology and hepatology

authors： Ding Z,Zhuo L

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Infection with hepatitis E virus (HEV) is a major cause of acute viral hepatitis in several developing countries. Although usually self-limiting and benign, the disease is particularly severe among pregnant women, with mortality rates reaching 15-20%. METHODS:Immune parameters among pregnant women with acut...

journal_title：Journal of gastroenterology and hepatology

authors： Pal R,Aggarwal R,Naik SR,Das V,Das S,Naik S

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Because most of the characteristics of the portal hypertensive enteropathy can be explained on the basis of increased levels of mast cell mediators, the purpose of the present paper was to study mast cell splanchnic infiltration. METHODS:Duodenum, jejunum, ileum and mesenteric lymph node complex infiltratio...

journal_title：Journal of gastroenterology and hepatology

authors： Prieto I,Aller MA,Santamaría L,Nava MP,Madero R,Pérez-Robledo JP,Arias J

更新日期：2005-07-01 00:00:00

abstract：:Despite steady progress in antiviral treatment for patients with chronic hepatitis C virus(HCV), many patients still have detectable serum HCV RNA levels by the end of interferon-based treatment and are known as virological non-responders. Re-treatment of these patients not responding to previous therapy remains chall...

journal_title：Journal of gastroenterology and hepatology

authors： Poo JL,Sánchez-Avila F,Kershenobich D,García-Samper X,Gongora J,Uribe M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The liver is the major iron storage organ in the body and, as a result, total body iron stores closely regulate hepatocyte iron uptake, storage and release. Transferrin, transferrin receptor and ferritin facilitate these processes. METHODS:Expression of the three proteins was localized by immunohistochemist...

journal_title：Journal of gastroenterology and hepatology

authors： Basclain KA,Jeffrey GP

更新日期：1999-07-01 00:00:00

abstract：:Dysbiosis in the gut microbiota composition due to environmental or genetic variations can disrupt the immune system and may promote several diseases such as colorectal cancer (CRC). Gut microbiota can alter the toxicity and efficiency of an extensive range of CRC treatment methods, especially surgery, chemotherapy, r...

journal_title：Journal of gastroenterology and hepatology

authors： Taghinezhad-S S,Mohseni AH,Fu X

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND AND AIM:The aim of this study was to assess the gastric histopathology and serum gastrin-17 and pepsinogens profiles in patients with duodenal ulcer before and after Helicobacter pylori eradication in a population with a very high prevalence of H. pylori. At the same time we assessed the role of H. pylori de...

journal_title：Journal of gastroenterology and hepatology

authors： Pimanov SI,Makarenko EV,Voropaeva AV,Matveenko ME,Voropaev EV

更新日期：2008-11-01 00:00:00

abstract：:The transjugular intrahepatic portosystemic stent-shunt (TIPS) technique consists of a transhepatic puncture of the portal vein and stenting of the parenchymal tract between the hepatic and portal veins. Complications of both puncture and stenting are observed in approximately 5% of procedures. Most of the complicatio...

journal_title：Journal of gastroenterology and hepatology

authors： Rössle M,Haag K,Blum HE

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND AND AIM:The incidence of colorectal cancer (CC) is increasing in many Asian countries, but decreasing in western countries. The present study examined the local incidence of CC in the past few decades. METHODS:A population based study, using data from Hong Kong (HK) Cancer Registry, was carried out to exami...

journal_title：Journal of gastroenterology and hepatology

authors： Yee YK,Gu Q,Hung I,Tan VP,Chan P,Hsu A,Pang R,Lam CS,Wong BC

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Interstitial cells of Cajal (ICCs), which express c-Kit receptor tyrosine kinase (KIT), play an important role in gastrointestinal motility. Loss of ICCs likely contributes to diabetic gastrointestinal motility disorder, however, the mechanism of attrition remains unknown. Here, we test the hypothesis that t...

journal_title：Journal of gastroenterology and hepatology

authors： Li Y,Kojima H,Fujino K,Matsumura K,Katagi M,Urabe H,Chan L,Eguchi Y,Zhao L,Kimura H

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND AIM:We recently conducted a randomized placebo-controlled trial on the efficacy and safety of rikkunshito, a standardized Japanese herbal medicine, for the treatment of functional dyspepsia (FD). The present post-hoc study aimed to evaluate the differences in clinical characteristics between responders a...

journal_title：Journal of gastroenterology and hepatology

authors： Togawa K,Matsuzaki J,Kobayakawa M,Fukushima Y,Suzaki F,Kasugai K,Nishizawa T,Naito Y,Hayakawa T,Kamiya T,Andoh T,Yoshida H,Tokura Y,Nagata H,Mori M,Kato K,Hosoda H,Takebayashi T,Miura S,Uemura N,Joh T,Hibi T,S

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Disorders of the motor function of the upper gastrointestinal tract have been implicated in the pathogenesis of non-ulcer dyspepsia. Approximately 50% of patients with abdominal symptoms (without ulcer) have normal gastric emptying. Apart from gastric emptying, other mechanisms are very important in the etio...

journal_title：Journal of gastroenterology and hepatology

authors： Mizushima T,Sawa K,Ochi K,Tanioka H,Wakuta A,Matsushita K,Shirahige A,Kiura K,Tanimoto M,Koide N,Harada H

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Emerging evidence suggests aldosterone (aldo) and NLRP3 inflammasome are important factors for HSC activation and liver fibrosis. However, the interaction between aldo and NLRP3 inflammasome in HSC activation and liver fibrosis remains largely unknown. The aim of this study is to investigate the rel...

journal_title：Journal of gastroenterology and hepatology

authors： Li Y,Zhang Y,Chen T,Huang Y,Zhang Y,Geng S,Li X

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND AIM:This study aimed to estimate the time to precursor progression and to identify significant predicators. METHODS:One hundred thirty-three precursor and 311 normal cases detected in a population-based screening were surveyed for 5.5 years. Precursor progression was defined as worsening of dysplasia or...

journal_title：Journal of gastroenterology and hepatology

authors： Wen D,Zhang L,Wang X,Li Y,Ma C,Liu X,Zhang J,Wen X,Yang Y,Zhang F,Wang S,Shan B

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatocellular carcinoma (HCC) remains a serious cause of cancer-related deaths worldwide. Developing new therapeutic strategies is urgently needed to improve the outcomes of HCC patients. Dendritic cell (DC)-based vaccines and programmed death 1 (PD-1) immune checkpoint inhibitors have been regarded...

journal_title：Journal of gastroenterology and hepatology

authors： Teng CF,Wang T,Shih FY,Shyu WC,Jeng LB

更新日期：2021-01-19 00:00:00

abstract：BACKGROUND AND AIM:Current treatments of functional dyspepsia (FD) are unsatisfied. Tricyclic antidepressants alter visceral hypersensitivity and brain-gut interaction. We assessed the efficacy and safety of nortriptyline in patients with FD. METHODS:Patients diagnosed with FD according to Rome III criteria who failed...

journal_title：Journal of gastroenterology and hepatology

authors： Kaosombatwattana U,Pongprasobchai S,Limsrivilai J,Maneerattanaporn M,Leelakusolvong S,Tanwandee T

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND AND AIM:No prospective data are available on comparing covered and uncovered self-expandable metal stent (SEMS) for reintervention of occluded uncovered metal stents during endoscopic retrograde cholangiopancreatography in patients with malignant distal biliary obstruction. METHODS:From June 2010 to Novembe...

journal_title：Journal of gastroenterology and hepatology

authors： Lee BS,Ryu JK,Jang DK,Chung KH,Yoon WJ,Kim J,Woo SM,Lee SH,Lee WJ,Kim YT

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND AND AIM:Helicobacter pylori infection in gastric mucosa is a form of chronic active gastritis that leads to expression of inducible nitric oxide synthase in host macrophages and polymorphonuclear leukocytes. Nitric oxide produced by these cells infiltrating the gastric mucosa could damage DNA. We correlated ...

journal_title：Journal of gastroenterology and hepatology

authors： Tari A,Kodama K,Kitadai Y,Ohta M,Sumii K,Kajiyama G

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatocellular carcinoma (HCC) is characteristically a hypervascular tumor and its progression is known to be closely related to angiogenesis. In this study, we investigated angiopoietin-2 (Ang-2) and vascular endothelial growth factor (VEGF) levels in the hepatic vein draining from HCC, as well as i...

journal_title：Journal of gastroenterology and hepatology

authors： Kuboki S,Shimizu H,Mitsuhashi N,Kusashio K,Kimura F,Yoshidome H,Ohtsuka M,Kato A,Yoshitomi H,Miyazaki M

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIM:It has been reported that immunological factors, such as the T-helper cell (Th)1/Th2 ratio, play a part in the mechanisms for the antihepatitis C virus (HCV) effect of the interferon (IFN) alpha-2b plus ribavirin combination therapy. By using flow cytometry, we examined this ratio during a 24-week co...

journal_title：Journal of gastroenterology and hepatology

authors： Fujimoto T,Tomimatsu M,Iga D,Endo H,Otsuka K

更新日期：2008-08-01 00:00:00

abstract：:Eradication of Helicobacter pylori infection is known to reduce the incidence of duodenal ulcer recurrence. The most commonly used regimen for H. pylori infection is triple antimicrobial therapy for 1-2 weeks. This treatment is associated with frequent side effects and hence unsatisfactory compliance. As in vitro data...

journal_title：Journal of gastroenterology and hepatology

authors： Sung JJ,Chung SC,Hosking SW,Chan RC,Ling TK,Yung MY,Cheng AF,Li AK

更新日期：1995-01-01 00:00:00

abstract：:Cell proliferation in the gastroduodenal mucosa of patients with duodenal ulcers was evaluated using flow cytometry. Forty patients with duodenal ulcers and 12 normal subjects were investigated. Biopsy samples were obtained during endoscopic examination and subjected to DNA analysis by flow cytometry. Thirty patients ...

journal_title：Journal of gastroenterology and hepatology

authors： Kobayashi I,Kawano S,Tsuji S,Nakama A,Sawaoka H,Masuda E,Nagano K,Fusamoto H,Kamada T

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND AND AIM:The aim of this study is to evaluate the association of the regulatory T cells (Treg)/T-helper (Th) 17 cells and transforming growth factor-β1 (TGF-β1)/interleukin-17 (IL-17) ratios with the survival and disease progression in patients with hepatitis B virus (HBV)-associated liver cirrhosis (LC). ME...

journal_title：Journal of gastroenterology and hepatology

authors： Yu X,Guo R,Ming D,Su M,Lin C,Deng Y,Lin Z,Su Z

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND AND AIM:Ulcerative colitis (UC) is a multifactorial disease resulting from a complex interaction of genetic and environmental factors. Identifying genetic variants that alter the innate immune response is highly relevant to understanding the pathogenesis of UC. The aim of this study was to investigate the as...

journal_title：Journal of gastroenterology and hepatology

authors： Wang F,Tahara T,Arisawa T,Shibata T,Nakamura M,Fujita H,Iwata M,Kamiya Y,Nagasaka M,Takahama K,Watanabe M,Hirata I,Nakano H

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:All gut movements are claimed to be activated essentially by the concentric contraction of the circular muscle, moving the chyme aborally. The role of the longitudinal smooth muscle of the small intestine in gut motility is poorly understood; this point was investigated in the current study. METHODS:The abd...

journal_title：Journal of gastroenterology and hepatology

authors： Shafik A,Shafik AA,Ahmed I

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND AND AIM:The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD. METHODS:The study was designed as a multicenter, randomiz...

journal_title：Journal of gastroenterology and hepatology

authors： Xiao Y,Li Y,Shu J,Li Y,Xu J,Ren J,Liu D,Wang J,Zhou L,Li Y,Tang G,Tian D,Zhang S,Hou X,Wang H,Li Z,Lv N,Chen M

更新日期：2019-03-01 00:00:00

abstract：:A case is described of a 58 year old Caucasian male with primary biliary cirrhosis (PBC) who first presented with acanthosis nigricans of both axillae, skin pigmentation, which was pronounced over the posterior surface of the neck, and generalized pruritus. Following orthotopic liver transplantation for progressive li...

journal_title：Journal of gastroenterology and hepatology

authors： Pham TH,Kaushik S,Lin BP,Jones DB

更新日期：1996-11-01 00:00:00

abstract：:In November 2001, a 29-year-old woman was admitted to the hospital because of dysphagia due to an apallic state caused by cerebral anoxia. Nutritional support was maintained by nasogastric tube feeding for approximately 3 months. For improvement of the body state maintenance and quality of life, a percutaneous endosco...

journal_title：Journal of gastroenterology and hepatology

authors： Chen W,Kawahara H,Takahasi M,Matsushima A,Takase S

更新日期：2006-05-01 00:00:00