Therapeutic efficacy of dendritic cell vaccine combined with programmed death 1 inhibitor for hepatocellular carcinoma.

abstract：:Hepatitis E, caused by infection with hepatitis E virus (HEV), is a common cause of acute hepatitis in areas with poor sanitation. The virus has four genotypes with one serotype: genotypes 1 and 2 exclusively infect humans, whereas genotypes 3 and 4 also infect other animals, particularly pigs. In endemic areas, both ...

journal_title：Journal of gastroenterology and hepatology

authors： Aggarwal R,Naik S

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The role of Helicobacter pylori infection in gastroduodenal lesions might be different between the general population and AIDS patients. The aim of the present study was to compare the prevalence of H. pylori and cytomegalovirus (CMV) infection in AIDS patients and HIV-negative controls. The impact ...

journal_title：Journal of gastroenterology and hepatology

authors： Chiu HM,Wu MS,Hung CC,Shun CT,Lin JT

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND AND AIM:Hyperphosphatemia has been implicated in the development and treatment of various cancers. However, whether it can be used as a direct prognostic marker of colorectal cancer (CRC) has remained unexplored. Given new insights into the importance of hyperphosphatemia in CRC, we sought to evaluate the as...

journal_title：Journal of gastroenterology and hepatology

authors： Ye Z,Palazzo JP,Lin L,Lai Y,Guiles F,Myers RE,Han J,Xing J,Yang H

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND AIM:Although endoscopic ultrasound-guided fine-needle biopsy is widely applied, there is no clear consensus on the optimal biopsy technique. We described a modified wet suction technique (MWEST) with the aim to compare the efficacy and safety between MWEST and the dry suction technique (DST). METHODS:In...

journal_title：Journal of gastroenterology and hepatology

authors： Tong T,Tian L,Deng M,Liu Y,Yang Y,Yin H,Long X,Pan S,Yang Z,Luo W,Nie K,Meng X,Xiao M,Wu X,Zhang C,Wang X

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND AND AIM:The attenuated antisecretory activity of H2 receptor antagonists (H2RA) during continuous administration is known as the tolerance phenomenon. The authors recently clarified that presence or absence of Helicobacter pylori infection influences the occurrence of the tolerance phenomenon. The aim of thi...

journal_title：Journal of gastroenterology and hepatology

authors： Furuta K,Adachi K,Komazawa Y,Mihara T,Miki M,Azumi T,Fujisawa T,Katsube T,Kinoshita Y

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND AND AIM:Helicobacter pylori cagA can be classified into mainly two types (East-Asian-type and Western-type cagA) according to the repeat regions located in the 3' region. Recent studies showed that the Western-type cagA in strains from Okinawa, Japan formed a different cluster (J-Western-type cagA subtype). ...

journal_title：Journal of gastroenterology and hepatology

authors： Matsuo Y,Shiota S,Matsunari O,Suzuki R,Watada M,Binh TT,Kinjo N,Kinjo F,Yamaoka Y

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND AIM:DNA methylation is an important epigenetic modification that can promote the development of various cancers. The STAT1 and SOCS3 have been observed to be hypermethylated in tumor tissues and peripheral blood. This study aimed to explore the relationship between the methylation status of the STAT1 and...

journal_title：Journal of gastroenterology and hepatology

authors： Han Q,Zhou H,Xie W,Sun T,Wei R,Nie C,Hong J,Zhu L,Tian W

更新日期：2020-08-01 00:00:00

abstract：:We examined whether a single inoculation of Helicobacter pylori can colonize the stomachs of ulcerated rats and delay their healing and whether an antibiotic drug and acid pump inhibitors can enhance the ulcer healing in infected rats. Ulcers were produced by a submucosal injection of acetic acid solution into the gas...

journal_title：Journal of gastroenterology and hepatology

authors： Li T,Okabe S

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND AIMS:A relatively large number of patients with multiple myeloma have been reported to develop a secondary malignancy such as cancer of the breast, biliary system or bowel. METHODS:A retrospective study was perfomed in 734 patients with hematologic disease diagnosed at Nippon Medical School Hospital bet...

journal_title：Journal of gastroenterology and hepatology

authors： Kishida T,Yonezawa M,Shibata Y,Tanaka S,Shinozawa I,Hoshino T,Tatsuguchi A,Feng L,Sato J,Fujimori S,Yoshida Y,Sakamoto C,Kobayashi M

更新日期：2000-11-01 00:00:00

abstract：:Three clinicopathological phases of chronic hepatitis B virus (HBV) infection are identified. First, is immune tolerance of HBV. High levels of viraemia are associated with normal alanine aminotransferase (ALT) levels and minimal histological lesions. More than 30-40% of hepatocytes have the hepatitis B core antigen (...

journal_title：Journal of gastroenterology and hepatology

authors： Chu CM,Liaw YF

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:The clinicopathological profiles and outcome of chronic hepatitis B can differ by hepatitis B virus (HBV) genotypes. In Japan, genotype B and C are two major HBV genotypes. The basic core promoter and precore mutations are other known viral factors for disease activity, although the relationship between HBV ...

journal_title：Journal of gastroenterology and hepatology

authors： Watanabe K,Takahashi T,Takahashi S,Okoshi S,Ichida T,Aoyagi Y

更新日期：2005-03-01 00:00:00

abstract：:The exact pathogenesis of centrilobular necrosis following congestion of the liver is still unknown. We reviewed the clinical data related to systemic circulatory disturbance and histopathology of the liver and the gut in 320 autopsy subjects. Congestion of the liver alone was associated only with atrophy and loss of ...

journal_title：Journal of gastroenterology and hepatology

authors： Shibayama Y,Urano T,Asaka S,Hashimoto K,Nakata K

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND AND AIM:To present the experience in management of inflammatory liver pseudotumors from a specialist surgical unit and to review the medical literature on this rare manifestation. METHODS:Between 1995 and 2008, four patients were identified with this type of tumor from a total of 108 resected benign liver l...

journal_title：Journal of gastroenterology and hepatology

authors： Milias K,Madhavan KK,Bellamy C,Garden OJ,Parks RW

更新日期：2009-09-01 00:00:00

abstract：:The aetiology of idiopathic portal hypertension or hepatoportal sclerosis is unknown. In view of the indirect evidence for underlying immunologic abnormalities 14 patients (all middle-aged females) were studied. Various auto-antibodies were demonstrated in seven patients and high levels of serum immunoglobulins, eithe...

journal_title：Journal of gastroenterology and hepatology

authors： Tokushige K,Komatsu T,Ohzu K,Yamauchi K,Obata H

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND AND AIM:In general, the spleen is one of the abdominal organs connected by the portal system, and a splenectomy improves hepatic functions in the settings of partial hepatectomy (Hx) for portal hypertensive cases or living donor liver transplantation with excessive portal vein flow. Those precise mechanisms ...

journal_title：Journal of gastroenterology and hepatology

authors： Arakawa Y,Shimada M,Utsunomiya T,Imura S,Morine Y,Ikemoto T,Mori H,Kanamoto M,Iwahashi S,Saito Y,Takasu C

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Biliary disease is one of the most common causes of acute pancreatitis in adults; however, this cause and outcome in children have rarely been described in the literature. Therefore, the present study was conducted to evaluate the role of biliary disease as a cause of acute pancreatitis in children....

journal_title：Journal of gastroenterology and hepatology

authors： Choi BH,Lim YJ,Yoon CH,Kim EA,Park YS,Kim KM

更新日期：2003-08-01 00:00:00

abstract：:Apoptosis, a programmed cell death, was ignored, just like Helicobacter pylori, only to reappear recently. However, the number of current publications dealing with apoptosis or H. pylori has increased exponentially. Although gastric epithelial apoptosis is a programmed physiological event in the superficial aspect of ...

journal_title：Journal of gastroenterology and hepatology

authors： Suzuki H,Ishii H

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND AND AIM:Since the advent of direct-acting antiviral (DAA) therapy, the total eradication of hepatitis C virus has been achievable with the recovery of hepatic reserve after achievement of sustained virologic response (SVR). Hence, here, we examined the factors affecting the recovery of hepatic reserve. METH...

journal_title：Journal of gastroenterology and hepatology

authors： Nakajima T,Karino Y,Hige S,Suii H,Tatsumi R,Yamaguchi M,Arakawa T,Kuwata Y,Hasegawa T,Toyota J

更新日期：2020-09-29 00:00:00

abstract：BACKGROUND AND AIM:KRAS mutation analysis may provide ancillary diagnostic yield in an endoscopic ultrasound (EUS)-guided histopathological evaluation. We evaluated the clinical impact of KRAS mutation analysis with cytological and histological evaluations in EUS-guided tissue sampling, using a core biopsy needle for s...

journal_title：Journal of gastroenterology and hepatology

authors： Choi HJ,Moon JH,Kim HK,Lee YN,Lee TH,Cha SW,Cho YD,Park SH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND AIM:Recent studies have shown that imbalance between tumor-infiltrating interleukin (IL)-17(+) T cells and regulatory T cells (Tregs) is an important regulator of progression in various cancers, but little is known regarding this imbalance in hepatocellular carcinoma (HCC). This study explored the role o...

journal_title：Journal of gastroenterology and hepatology

authors： Huang Y,Wang F,Wang Y,Zhu Z,Gao Y,Ma Z,Xu R,Du Z

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:The purpose of the present paper was to investigate dendritic cell (DC) and T-cell functions in patients with chronic hepatitis B (CHB) and determine whether therapeutic DC vaccines could restore T-cell function in those patients in vitro. METHODS:Twelve patients with CHB and 10 normal control subjects with...

journal_title：Journal of gastroenterology and hepatology

authors： Duan XZ,He HX,Zhuang H

更新日期：2006-06-01 00:00:00

abstract：:Prostaglandin E1 (PGE1) has been reported to have, experimentally and clinically, a protective effect against liver damage. This effect may result from the relaxation of hepatic stellate cells, whose contraction induces vasoconstriction of hepatic sinusoids. However, prostaglandins are unstable and a new drug delivery...

journal_title：Journal of gastroenterology and hepatology

authors： Wang XE,Watanabe S,Oide H,Hirose M,Itatsu T,Osada T,Takazakura Y,Yokoi Y,Sato N

更新日期：1998-09-01 00:00:00

abstract：:The reproducibility of echo-Doppler measurements of portal vein and superior mesenteric artery blood flow has not been extensively studied. In the present study, two groups of subjects were examined to test inter- and intra-observer reproducibility. Each study population consisted of 15 nonportal hypertensive and 15 p...

journal_title：Journal of gastroenterology and hepatology

authors： Iwao T,Toyonaga A,Shigemori H,Oho K,Sumino M,Sato M,Tanikawa K

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND AIM:Chronic inflammation is a major contributor to the initiation and progression of cancers. Lactobacillus helveticus NS8, which was originally separated from fermented koumiss, exhibited anti-inflammatory functions in our prior studies. In this study, NS8 was investigated for its potential to prevent c...

journal_title：Journal of gastroenterology and hepatology

authors： Rong J,Liu S,Hu C,Liu C

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:It has been reported that the branched-chain amino acid (BCAA) to tyrosine ratio (BTR) is a useful indicator of liver function and BCAA therapy is associated with a decreased incidence of hepatocellular carcinoma (HCC). However, there has not been sufficient research on the relationship between BTR a...

journal_title：Journal of gastroenterology and hepatology

authors： Tada T,Kumada T,Toyoda H,Kiriyama S,Tanikawa M,Hisanaga Y,Kanamori A,Kitabatake S,Yama T

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Epidemics pose a great challenge to health care of patients. However, the impact of unprecedented situation of COVID-19 outbreak on health care of inflammatory bowel disease (IBD) patients in real-world setting has seldom been investigated. METHODS:We performed an observational study in a tertiary ...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang YF,Qiu Y,He JS,Tan JY,Li XZ,Zhu LR,Chen Y,Liu ZJ,Iacucci M,Chen BL,He Y,Ben-Horin S,Shen B,Zeng ZR,Ghosh S,Chen MH,Mao R

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND AIM:It has recently been reported that Toll-like receptor 4 (TLR4) is involved in cellular responses to lipopolysaccharides (LPS) and early liver injury induced by LPS. The aim of the present study was to investigate the alterations of TLR4 gene expression in liver tissues and Kupffer cells during the co...

journal_title：Journal of gastroenterology and hepatology

authors： Hua J,Qiu DK,Li JQ,Li EL,Chen XY,Peng YS

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Resistance of Helicobacter pylori to the standard therapeutic antimicrobial agents has been demonstrated. Although quinolones are an alternative candidate for third-line eradication therapy, quinolone resistance of H. pylori is also increasing. Quinolone resistance of H. pylori is caused by a point ...

journal_title：Journal of gastroenterology and hepatology

authors： Matsuzaki J,Suzuki H,Tsugawa H,Nishizawa T,Hibi T

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND AIM:This study was designed to determine whether non-alcoholic fatty liver disease (NAFLD), with or without metabolic syndrome (MetS), is a risk factor for cancer development. METHODS:We conducted a retrospective longitudinal study at the Center for Preventive Medicine, St. Luke's International Hospital...

journal_title：Journal of gastroenterology and hepatology

authors： Yamamoto K,Ikeya T,Okuyama S,Fukuda K,Kobayashi D

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:Accumulation of endogenous opioids and overproduction of nitric oxide has been reported in cholestatic mice. It is well known that endogenous opioids and nitric oxide alter the susceptibility of experimental animals to different models of seizure. METHODS:The alterations in clonic seizure thresholds, induce...

journal_title：Journal of gastroenterology and hepatology

authors： Homayoun H,Sayyah M,Dehpour AR

更新日期：2002-01-01 00:00:00