Epidemiology, risk factors, and the promotion of pancreatic cancer: role of the stellate cell.

abstract：BACKGROUND AND AIMS:It is well known that endotoxemia, which is caused by a bacterial infection, can exacerbate acute pancreatitis, whereas pancreatitis-associated protein (PAP) has the ability to induce bacterial aggregation. Pancreatitis-associated protein is supposed to protect the tissue from infection during infla...

journal_title：Journal of gastroenterology and hepatology

authors： Wang X,Wang B,Wu J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND AIM:Thiopurines (TPs) are effective in reducing clinical and endoscopic recurrence in postoperative patients with Crohn's disease (CD). However, whether TPs could prevent surgical recurrence (SR) remains unknown. We aimed to explore whether TPs could prevent SR and identify risk factors associated with S...

journal_title：Journal of gastroenterology and hepatology

authors： Guo J,Chen BL,Chen ZH,Luo XP,Qiu Y,Zhang SH,Feng R,He Y,Zeng ZR,Song XM,Ben-Horin S,Mao R,Chen MH

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:We designed an animal model in order to clarify whether Helicobacter pylori infection causes the gastric mucosal lesion frequently seen in cirrhotic patients. METHODS:Ammonia (NH3) solution was given to rats with carbon tetrachloride-induced cirrhosis. The gastric mucosal hexosamine (Hx) content and histopa...

journal_title：Journal of gastroenterology and hepatology

authors： Sugimoto M,Machida Y,Ito K

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:To elucidate the incidence of the rare cases of icteric type hepatocellular carcinoma (IHCC), we conducted a retrospective study. The clinical outcomes of IHCC cases were also analyzed. METHODS:From January 1986 to December 1997, newly diagnosed HCC cases were evaluated and reviewed from an admission regist...

journal_title：Journal of gastroenterology and hepatology

authors： Huang JF,Wang LY,Lin ZY,Chen SC,Hsieh MY,Chuang WL,Yu MY,Lu SN,Wang JH,Yeung KW,Chang WY

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND AIM:This prospective pilot study investigated whether it is possible to predict the therapeutic response in both the early phase (1 week) and sustained phase (4 weeks) before starting proton pump inhibitor (PPI) therapy for functional dyspepsia (FD) or non-erosive reflux disease (NERD). METHODS:We admin...

journal_title：Journal of gastroenterology and hepatology

authors： Nagahara A,Miwa H,Asaoka D,Shimada Y,Sasaki H,Matsumoto K,Osada T,Hojo M,Watanabe S

更新日期：2015-03-01 00:00:00

abstract：:Affecting one fourth of the global population, non-alcoholic fatty liver disease (NAFLD) is the commonest chronic liver disorder. It encompasses the simple liver fat accumulation to more progressive steatosis, inflammation, and fibrosis characterized as non-alcoholic steatohepatitis (NASH) and in some cases cirrhosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Chrysavgis L,Papatheodoridi AM,Chatzigeorgiou A,Cholongitas E

更新日期：2020-07-27 00:00:00

abstract：:The Swift Increase in Alcohol Metabolism occurs within 2.5 h after an acute gavage of ethanol causing an increase in hepatic respiration, an increase in alcohol metabolism, and pericentral hypoxia in the perfused liver. Alcohol treatment causes a release of endotoxin, activation of Kupffer cells to produce PGE(2), the...

journal_title：Journal of gastroenterology and hepatology

authors： Bradford BU

更新日期：2007-06-01 00:00:00

abstract：:The preferred treatment for patients with chronic hepatitis C, either treatment-naive, relapsers or nonresponders to IFN monotherapy, is now IFN-ribavirin combination treatment. The adverse effects of IFN are well established and familiar to hepatologists all over the world. More than 25,000 patients worldwide have be...

journal_title：Journal of gastroenterology and hepatology

authors： Chutaputti A

更新日期：2000-05-01 00:00:00

abstract：:Pancreatic adenocarcinoma is one of the leading causes of cancer death in the West, with a poor overall 5-year survival rate of only 4%. Late clinical presentation with an advanced disease results in a low rate of surgical intervention. Tumor serum marker CA 19-9 is sensitive, although not specific for the diagnosis o...

journal_title：Journal of gastroenterology and hepatology

authors： Sahani DV,Shah ZK,Catalano OA,Boland GW,Brugge WR

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Endoscopic obliteration of esophageal varices by endoscopic variceal ligation (EVL) is an effective form of secondary prophylaxis. However, there is no consensus regarding the technical aspects of EVL for secondary prophylaxis. The present study compares the technical aspects of EVL (frequency of sessions,...

journal_title：Journal of gastroenterology and hepatology

authors： Harewood GC,Baron TH,Song LM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND AIM:Bacterial infections are among the main causes of death in patients with cirrhosis. While there are unquestionable benefits of using albumin in patients with spontaneous bacterial peritonitis, the benefits of albumin are controversial for those with extraperitoneal infections. The aim was to compare ...

journal_title：Journal of gastroenterology and hepatology

authors： Leão GS,John Neto G,Jotz RF,Mattos AA,Mattos ÂZ

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The bacterial beta-glucuronidase (bBG) can deconjugate conjugated bilirubin to form calcium bilirubinate gallstone. Yet, the role of the human biliary beta-glucuronidase (hBG) in the pathogenesis of pigment gallstone formation still remains unsolved. METHODS:Hepatic bile was collected from bile-duc...

journal_title：Journal of gastroenterology and hepatology

authors： Chen CY,Shiesh SC,Tsao HC,Lin XZ

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVES:The epidemiology of lower gastrointestinal bleeding (LGIB) in Western populations has been reported; however, there are scant Asian reports. The aim of the present study was to determine the etiology of LGIB in a Chinese population by reporting a retrospective case series and a systematic analysis of Chinese...

journal_title：Journal of gastroenterology and hepatology

authors： Bai Y,Peng J,Gao J,Zou DW,Li ZS

更新日期：2011-04-01 00:00:00

abstract：:Immune responses against hepatitis C virus (HCV) play a crucial role in the pathogenesis of chronic hepatitis C. HCV infection often persists and leads to chronic hepatitis and eventually cirrhosis. Accumulated data suggest that HCV proteins suppress host immune responses through the suppression of functions of immune...

journal_title：Journal of gastroenterology and hepatology

authors： Hiroishi K,Ito T,Imawari M

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND AIM:Colorectal cancer (CRC) screening is based on colonoscopy or fecal occult blood tests, but is imperfect and costly. The Asia Pacific Colorectal Screening Score (APCS) is derived from age, sex, family history of CRC, and smoking history and has been validated in Asian populations. Validation in a West...

journal_title：Journal of gastroenterology and hepatology

authors： Corte C,Zhang L,Chen J,Westbury S,Shaw J,Yeoh KG,Leong R

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND AIM:Estimates suggest that in Asia, more than 31 million individuals have hepatitis C virus infection. The present analysis was conducted to assess the efficacy and safety of elbasvir/grazoprevir in Asian participants enrolled in the elbasvir/grazoprevir phase 2/3 clinical trials. METHODS:This is an int...

journal_title：Journal of gastroenterology and hepatology

authors： Wei L,Kumada H,Perumalswami PV,Tanwandee T,Cheng W,Heo J,Cheng PN,Hwang P,Mu SM,Zhao XM,Asante-Appiah E,Caro L,Hanna GJ,Robertson MN,Haber BA,Talwani R

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:Because of its long duration, inflammatory bowel disease (IBD) causes high use of health services and high lifetime costs for medical care. The aim of the present study was to measure the costs of outpatient care in patients with IBD in a German University Hospital and to identify potentially relevan...

journal_title：Journal of gastroenterology and hepatology

authors： Ebinger M,Leidl R,Thomas S,Von Tirpitz C,Reinshagen M,Adler G,Konig HH

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND AND AIM:To study the histological changes caused by transfection of the hepatocyte growth factor (HGF) gene using electroporation (EP) in a non-alcoholic steatohepatitis (NASH) cirrhotic liver model. METHODS:NASH cirrhotic livers were prepared by administering a choline-deficient diet to 5-week-old male Wis...

journal_title：Journal of gastroenterology and hepatology

authors： Kiyama S,Yamada T,Iwata H,Sekino T,Matsuo H,Yoshida N,Miyahara T,Umeda Y,Matsuno Y,Kimura M,Matsumoto K,Nakamura T,Takemura H

更新日期：2008-08-01 00:00:00

abstract：:The low Fermentable Oligosaccharides, Disaccharides, and Monosaccharides And Polyols (FODMAP) diet has been described, evaluated, and found efficacious for the treatment of patients with irritable bowel syndrome primarily in Western countries. The aim of this review was to address the applicability of this diet to Sou...

journal_title：Journal of gastroenterology and hepatology

authors： Hewawasam SP,Iacovou M,Muir JG,Gibson PR

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Overexpression of signaling proteins including epidermal growth factor receptor (EGFR), Akt, mitogen activated protein kinase (MAPK) and cyclooxygenase-2 (COX-2) occurs in cholangiocarcinoma cell lines. However, the prognostic value of these markers is unknown. No prior study correlated the expression of the...

journal_title：Journal of gastroenterology and hepatology

authors： Javle MM,Yu J,Khoury T,Chadha KS,Iyer RV,Foster J,Kuvshinoff BW,Gibbs JF,Geradts J,Black JD,Brattain MG

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND AND AIM:To investigate a possible association between HLA genes with serum alanine aminotransferase (ALT) levels and evaluate whether the HLA-DQA1, DQB1, and DRB1 genes could influence the development of liver damage in chronic hepatitis C. METHODS:A total of 145 patients with chronic hepatitis C virus (HCV...

journal_title：Journal of gastroenterology and hepatology

authors： Yu RB,Hong X,Ding WL,Tan YF,Zhang YX,Sun NX,Wu GL,Zhan SW,Ge DF

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND AND AIM:The ability to detect early squamous neoplasia of the esophagus can be enhanced considerably by iodine staining during endoscopic examination; however, there has been no study on distinguishing high-grade intra-epithelial squamous neoplasia from low-grade dysplasia by endoscopic examination. We assum...

journal_title：Journal of gastroenterology and hepatology

authors： Shimizu Y,Omori T,Yokoyama A,Yoshida T,Hirota J,Ono Y,Yamamoto J,Kato M,Asaka M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Cystinosis is a metabolic disease characterized by accumulation of cystine in different organs and tissues, leading to potentially life-threatening organ dysfunction. Infantile cystinosis typically leads to end-stage renal disease, necessitating renal replacement therapy. Liver disease in cystinosis is rare ...

journal_title：Journal of gastroenterology and hepatology

authors： Cornelis T,Claes K,Gillard P,Nijs E,Roskams T,Lombaerts R,Nevens F,Cassiman D

更新日期：2008-08-01 00:00:00

abstract：:Chronic pancreatitis (CP) is a disease characterized by irreversible destruction and fibrosis of the parenchyma, leading to pancreatic exocrine insufficiency. In developed countries, the etiology for 60% to 70% of CP amongst male patients is alcohol and 25% are classified as idiopathic chronic pancreatitis (ICP). The ...

journal_title：Journal of gastroenterology and hepatology

authors： Reddy DN,Prasad SS

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND AIM:The PyloriTek Test Kit (a 1-h rapid urease test) was developed for the rapid diagnosis of Helicobacter pylori (H. pylori) during endoscopy. Most studies were performed in Western populations. The aim of this study was to evaluate the PyloriTek test for the diagnosis of H. pylori infection in Chinese ...

journal_title：Journal of gastroenterology and hepatology

authors： Wong WM,Wong BC,Tang VS,Lai KC,Yuen ST,Leung SY,Hu WH,Lam SK

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Because most of the characteristics of the portal hypertensive enteropathy can be explained on the basis of increased levels of mast cell mediators, the purpose of the present paper was to study mast cell splanchnic infiltration. METHODS:Duodenum, jejunum, ileum and mesenteric lymph node complex infiltratio...

journal_title：Journal of gastroenterology and hepatology

authors： Prieto I,Aller MA,Santamaría L,Nava MP,Madero R,Pérez-Robledo JP,Arias J

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis C virus (HCV) and environmental hepatotoxins may have an indirect influence on health by altering the synthesis and function of hormones, particularly reproductive hormones. We aimed to evaluate liver diseases and sex steroid hormones in Egypt, which has the highest prevalence of HCV worldw...

journal_title：Journal of gastroenterology and hepatology

authors： Aguilar CE,Soliman AS,McConnell DS,Zekri AR,Banerjee M,Omar A,Sharawy M,Omar S,Raouf A,Sowers MR

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIM:Although rabeprazole (RPZ), a proton pump inhibitor, has been reported to have a bactericidal effect on Helicobacter pylori (H. pylori), no studies have been conducted regarding the effect of RPZ on gastric mucosal lesion formation caused by this bacterium. In the present study, we investigated the e...

journal_title：Journal of gastroenterology and hepatology

authors： Suzuki H,Miyazawa M,Nagahashi S,Sato M,Bessho M,Nagata H,Miura S,Ishii H

更新日期：2003-07-01 00:00:00

abstract：:Ulcerative colitis (UC) and Crohn's disease (CD) comprise the idiopathic inflammatory bowel diseases (IBD) of the gut. The etiology of IBD is poorly understood, but an autoimmune disturbance has been suggested to play an important role in this incurable disease. Extracorporeal leukocytapheresis (CAP) is an additional ...

journal_title：Journal of gastroenterology and hepatology

authors： Fukunaga K,Matsumoto T

更新日期：2012-06-01 00:00:00

abstract：:Ceftriaxone-associated sludge has been a fascinating story. The occurrence is novel and unique. It has produced a model of gall-bladder sludge in humans. This phenomenon has taught us a great deal about biliary lipid and organic anion excretion by the liver, and the physical chemistry of calcium and calcium sensitive ...

journal_title：Journal of gastroenterology and hepatology

authors： Kim YS,Kestell MF,Lee SP

更新日期：1992-11-01 00:00:00