Immune responses in hepatitis C virus infection and mechanisms of hepatitis C virus persistence.

abstract：BACKGROUND AND AIM:Early life exposure to the famine may affect the susceptibility to the metabolic disorders. The objective of this study was to examine the associations of early life exposure to the Chinese Famine (1959-1961) with the risk of fatty liver disease, obesity, hypertension, and hyperglycemia in adulthood....

journal_title：Journal of gastroenterology and hepatology

authors： Chen JP,Peng B,Tang L,Sun R,Hu S,Wen XY,Que P,Wang YH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIM:HFE mutations, a common cause of hereditary hemochromatosis (HH), are reportedly associated with hepatic iron overload, severe liver fibrosis, and good response to interferon treatment in European patients with chronic hepatitis C (CHC). HH shows ethnicity-based differences and little is known about ...

journal_title：Journal of gastroenterology and hepatology

authors： Ishizu Y,Katano Y,Honda T,Hayashi K,Ishigami M,Itoh A,Hirooka Y,Nakano I,Goto H

更新日期：2012-06-01 00:00:00

abstract：:The aetiology of idiopathic portal hypertension or hepatoportal sclerosis is unknown. In view of the indirect evidence for underlying immunologic abnormalities 14 patients (all middle-aged females) were studied. Various auto-antibodies were demonstrated in seven patients and high levels of serum immunoglobulins, eithe...

journal_title：Journal of gastroenterology and hepatology

authors： Tokushige K,Komatsu T,Ohzu K,Yamauchi K,Obata H

更新日期：1992-05-01 00:00:00

abstract：:Infection by verocytotoxin-producing Escherichia coli (VTEC) is prevalent in many parts of the world but relatively uncommon in Asia, except Japan. A territory wide screening for VTEC (April to August 1996) in diarrhoeal stool samples sent to six hospital microbiology laboratories in Hong Kong revealed only four isola...

journal_title：Journal of gastroenterology and hepatology

authors： Wong S,Yam WC,Leung P,Woo P,Yuen KY

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND AND AIM:There are few studies investigating the treatment of hepatitis C virus (HCV) infection in current and former drug users. With this in mind, we sought to evaluate the antiviral efficacy of interferon alpha-2b (IFN alpha-2b) or pegylated-interferon alpha-2b (PEG-IFN alpha-2b) and ribavirin (RBV) in inj...

journal_title：Journal of gastroenterology and hepatology

authors： Grebely J,Raffa JD,Meagher C,Duncan F,Genoway KA,Khara M,McLean M,Mead A,Viljoen M,DeVlaming S,Fraser C,Conway B

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND AIM:Few studies have evaluated sustained virological response (SVR) rates by direct-acting agents (DAAs) and liver stiffness measurement (LSM) changing post-SVR in limited-resource settings. We aimed to describe the effectiveness of DAAs for hepatitis C virus treatment and to assess the changing of LSM p...

journal_title：Journal of gastroenterology and hepatology

authors： Fernandes FF,Piedade J,Guimaraes L,Nunes EP,Chaves U,Goldenzon RV,Cardoso SW,Duarte J,Grinsztejn B,Veloso VG,Pereira G,Perazzo H

更新日期：2019-12-01 00:00:00

abstract：:A randomized controlled trial was designed to investigate whether a high dose of terlipressin could control acute variceal haemorrhage more effectively than a low dose of terlipressin. Forty cirrhotic patients with bleeding oesophageal varices were included, with low-dose terlipressin in 21 patients and high-dose terl...

journal_title：Journal of gastroenterology and hepatology

authors： Chang TT,Lee FY,Tsai YT,Lai KH,Chao Y,Hsia HC,Lin HC,Wang SS,Lee SD,Lo KJ

更新日期：1991-09-01 00:00:00

abstract：:During 1981-86, 76 children were diagnosed as having acute viral hepatitis at the Department of Pediatrics, National Taiwan University Hospital, which is a major referral centre for hepatitis in children in northern Taiwan. The majority (64%) of children had acute hepatitis B which had occurred mainly during infancy. ...

journal_title：Journal of gastroenterology and hepatology

authors： Huang LM,Chang MH,Hong JY,Lee CY,Chen DS

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND AND AIM:Pathological grading is important in defining the therapeutic strategy in pancreatic neuroendocrine neoplasm (PNEN) but is difficult for unresectable cases. Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) is useful in the diagnosis of PNEN, but its usefulness for pathological grading ...

journal_title：Journal of gastroenterology and hepatology

authors： Horiguchi S,Kato H,Shiraha H,Tsutsumi K,Yamamoto N,Matsumoto K,Tomoda T,Uchida D,Akimoto Y,Mizukawa S,Tanaka T,Ichimura K,Takaki A,Yagi T,Okada H

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The classification of gastritis by using the revised Sydney system suggests that there are two types of Helicobacter pylori-related gastritis. The aim of the present study was to examine the risk factors that might be involved in the presence of either atrophic gastritis or intestinal metaplasia of ...

journal_title：Journal of gastroenterology and hepatology

authors： Tsukui T,Kashiwagi R,Sakane M,Tabata F,Akamatsu T,Wada K,Futagami S,Miyake K,Sueoka N,Hirakawa T,Kobayashi M,Fujimori T,Sakamoto C

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Lung injury is an important target for the systemic inflammatory response associated with intestinal ischemia/reperfusion (I/R). In the present study, the role of interleukin (IL)-18 in the development of acute pulmonary injury induced by intestinal I/R and its possible mechanism in relation to the ...

journal_title：Journal of gastroenterology and hepatology

authors： Yang YJ,Chen SH,Ge XR

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND AIM:This study sought to investigate the effects of hypothermia induced by adenosine 5'-monophosphate (5'-AMP) on L-arginine (L-Arg)-induced acute pancreatitis in rats. METHODS:The rats were divided into four groups: the control group, the acute pancreatitis group, the 5'-AMP pretreatment group, and the...

journal_title：Journal of gastroenterology and hepatology

authors： Wang Y,Guo W,Li Y,Pan X,Lv W,Cui L,Li C,Wang Y,Yan S,Zhang J,Liu B

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND AIM:Common endoscopic findings in stomachs with Helicobacter pylori infections include antral nodularity, thickened gastric folds, and visible submucosal vessels. These findings are suggestive but not diagnostic of H. pylori infection. Magnifying endoscopy can reveal more precisely the abnormal mucosal p...

journal_title：Journal of gastroenterology and hepatology

authors： Cho JH,Chang YW,Jang JY,Shim JJ,Lee CK,Dong SH,Kim HJ,Kim BH,Lee TH,Cho JY

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND AND AIM:The number of colonoscopies required to reach satisfactory adenoma detection rate (ADR) is not well established. The aim of this study was to identify the appropriate number of procedures required to attain satisfactory ADR for those well-trained endoscopists who have a cecal intubation rate (CIR) ≥ ...

journal_title：Journal of gastroenterology and hepatology

authors： Dong Z,Sun H,Li B,Zhang Q,Sun K,Wang Z,Qian X,Wang J,Zhan T,Jiang Y,Chen Y,Xu S

更新日期：2020-10-26 00:00:00

abstract：:In order to evaluate the relationship between local immune response to Helicobacter pylori and the diversity of disease, 77 asymptomatic subjects who underwent a health examination were studied. Helicobacter pylori-specific IgG in serum and H. pylori-specific IgA in gastric juice were measured by ELISA, and the measur...

journal_title：Journal of gastroenterology and hepatology

authors： Watanabe T,Goto H,Arisawa T,Hase S,Niwa Y,Hayakawa T,Asai J

更新日期：1997-10-01 00:00:00

abstract：:The main purpose of the present study was to demonstrate the incidence of Paneth cells in colorectal tubular adenomas of Japanese descendants in Hawaii. Paneth cells were found in 73 of 322 adenomas (22.7%) of Japanese descendants in Hawaii. The incidence of Paneth cells in adenomas located from the caecum to the tran...

journal_title：Journal of gastroenterology and hepatology

authors： Wada R,Kuwabara N,Suda K

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND AND AIM:T-cell activation, mediated by the interaction with major histocompatibility complex (MHC)-peptide complexes and B7 costimulatory molecules on antigen-presenting cells, is an essential event in the pathogenesis of inflammatory bowel disease (IBD). We investigated the expression of B7 costimulatory mo...

journal_title：Journal of gastroenterology and hepatology

authors： Grose RH,Howarth GS,Xian CJ,Hohmann AW

更新日期：2001-11-01 00:00:00

abstract：:Gastrointestinal (GI) manifestations of leukemia occur in up to 25% of patients at autopsy, generally during relapse. Its presence varies with the type of leukemia and has been decreasing over time due to improved chemotherapy. Gross leukemic lesions are most common in the stomach, ileum, and proximal colon. Leukemia ...

journal_title：Journal of gastroenterology and hepatology

authors： Ebert EC,Hagspiel KD

更新日期：2012-03-01 00:00:00

abstract：:The transjugular intrahepatic portosystemic stent-shunt (TIPS) technique consists of a transhepatic puncture of the portal vein and stenting of the parenchymal tract between the hepatic and portal veins. Complications of both puncture and stenting are observed in approximately 5% of procedures. Most of the complicatio...

journal_title：Journal of gastroenterology and hepatology

authors： Rössle M,Haag K,Blum HE

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Treatment of post-transplantation recurrence of hepatitis B virus (HBV) infection despite prophylaxis with hepatitis B immunoglobulin (HBIG) and lamivudine combination therapy is not easy. Because HBV reinfection has a severe course and could result in graft failure in liver transplant recipients, prompt med...

journal_title：Journal of gastroenterology and hepatology

authors： Akyildiz M,Karasu Z,Zeytunlu M,Aydin U,Ozacar T,Kilic M

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND AIM:The activation of Rho proteins has been shown to lead to loss of polarity in cancer cells, as well as reorganization of the cytoskeleton and facilitation of cell motility, possibly resulting in their malignant potential. The clinicopathological significance of RhoA, however, is not yet well known in ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang D,Dou K,Xiang H,Song Z,Zhao Q,Chen Y,Li Y

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND AIM:It has been reported that immunological factors, such as the T-helper cell (Th)1/Th2 ratio, play a part in the mechanisms for the antihepatitis C virus (HCV) effect of the interferon (IFN) alpha-2b plus ribavirin combination therapy. By using flow cytometry, we examined this ratio during a 24-week co...

journal_title：Journal of gastroenterology and hepatology

authors： Fujimoto T,Tomimatsu M,Iga D,Endo H,Otsuka K

更新日期：2008-08-01 00:00:00

abstract：:There are over 500-750 000 deaths per year because of hepatitis B virus (HBV)-related cirrhosis and liver cancer worldwide and the World Health Organization Western Pacific Region has some of the highest endemic levels of HBV in the world, particularly within China, South East Asia and Pacific Island Countries and Ter...

journal_title：Journal of gastroenterology and hepatology

authors： Howell J,Van Gemert C,Lemoine M,Thursz M,Hellard M

更新日期：2014-11-01 00:00:00

abstract：:Cell proliferation in the gastroduodenal mucosa of patients with duodenal ulcers was evaluated using flow cytometry. Forty patients with duodenal ulcers and 12 normal subjects were investigated. Biopsy samples were obtained during endoscopic examination and subjected to DNA analysis by flow cytometry. Thirty patients ...

journal_title：Journal of gastroenterology and hepatology

authors： Kobayashi I,Kawano S,Tsuji S,Nakama A,Sawaoka H,Masuda E,Nagano K,Fusamoto H,Kamada T

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:To elucidate the cause of possible occurrence of reflux esophagitis after Helicobacter pylori eradication, gastric and esophageal function among H. pylori infected Japanese patients were evaluated both before and after eradication therapy. METHODS:Nine H. pylori-positive patients were studied before and 6 m...

journal_title：Journal of gastroenterology and hepatology

authors： Tanaka I,Tatsumi Y,Kodama T,Kato K,Fujita S,Mitsufuji S,Kashima K

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND AND AIM:Covered metallic stents (CMSs) were developed to overcome tumor ingrowth in uncovered metallic stents (UMSs) for malignant biliary obstruction, but superiority of CMSs over UMSs is still controversial due to the high migration rate in CMS. Therefore, we conducted this retrospective analysis to clarif...

journal_title：Journal of gastroenterology and hepatology

authors： Nakai Y,Isayama H,Kogure H,Hamada T,Togawa O,Ito Y,Matsubara S,Arizumi T,Yagioka H,Mizuno S,Sasaki T,Yamamoto N,Hirano K,Tada M,Koike K

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND AIM:Repeated water avoidance stress (WAS) induces visceral hypersensitivity. Additionally, it is also known to activate corticotropin-releasing factor (CRF), mast cells, and pro-inflammatory cytokines systems, but their precise roles on visceral sensation have not been determined definitely. The aim of t...

journal_title：Journal of gastroenterology and hepatology

authors： Nozu T,Miyagishi S,Nozu R,Takakusaki K,Okumura T

更新日期：2017-12-01 00:00:00

abstract：AIM:To determine whether liver biopsy might be useful in the diagnosis of visceral leishmaniasis when bone marrow examination and serologic tests are inconclusive. METHODS:Over a 10-year period, liver biopsy was performed in five children with suspected visceral leishmaniasis when indirect hemagglutination tests and b...

journal_title：Journal of gastroenterology and hepatology

authors： Artan R,Yilmaz A,Akçam M,Aksoy NH

更新日期：2006-01-01 00:00:00

abstract：:Differentiation between gastric adenomas and type IIa early gastric cancer by macroscopic and histologic examinations is often difficult. This study has shown that there are differences in the distribution of S-phase cells in these two types of tumour, and these differences can be exploited to differentiate between th...

journal_title：Journal of gastroenterology and hepatology

authors： Miwa H,Wada R,Abe H,Ohkura R,Yang SW,Watanabe H,Ogihara T,Hamada T,Sato N

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND AND AIM:Epimorphin is suggested to play a key role in the morphogenesis of epithelial cells. We focused on epimorphin and attempted to clarify the relationship between expression of this molecule and inflammatory bowel disease (IBD). METHODS:Colonic specimens were taken from 23 patients with ulcerative coli...

journal_title：Journal of gastroenterology and hepatology

authors： Shirasaka T,Iizuka M,Yukawa M,Hirai Y,Horie Y,Itou H,Kon-No S,Fukushima T,Watanabe S

更新日期：2003-05-01 00:00:00