Abstract:
:During 1981-86, 76 children were diagnosed as having acute viral hepatitis at the Department of Pediatrics, National Taiwan University Hospital, which is a major referral centre for hepatitis in children in northern Taiwan. The majority (64%) of children had acute hepatitis B which had occurred mainly during infancy. Perinatal transmission from a hepatitis B e negative surface antigen (HBsAg) carrier mother or infection through blood transfusion from a donor who had escaped notice by a less sensitive screening test (reverse passive haemagglutination test) for HBsAg were the two important modes of transmission of hepatitis B virus. The number of cases of acute hepatitis B declined after 1984, with the beginning of the nation-wide hepatitis B vaccination programme. Due to an outbreak of hepatitis A in northern Taiwan in 1982, the number of cases of hepatitis A peaked that year. Subsequently, cases of acute hepatitis A decreased remarkably. Better socio-economic conditions and improved hygiene might have contributed to the marked decrease of viral hepatitis A. The frequency of non-A, non-B hepatitis remained stable during the study period. It is possible to conclude that the aetiologic pattern of acute hepatitis in Taiwanese children changed during the past 6 years: clinical cases of hepatitis A and B decreased, probably because of more effective control of hepatitis A and B virus infections, whereas the control of non-A, non-B virus apparently requires further efforts.
journal_name
J Gastroenterol Hepatoljournal_title
Journal of gastroenterology and hepatologyauthors
Huang LM,Chang MH,Hong JY,Lee CY,Chen DSdoi
10.1111/j.1440-1746.1989.tb00845.xsubject
Has Abstractpub_date
1989-07-01 00:00:00pages
339-44issue
4eissn
0815-9319issn
1440-1746journal_volume
4pub_type
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pub_type: 杂志文章
doi:10.1046/j.1440-1746.2001.02433.x
更新日期:2001-03-01 00:00:00
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更新日期:2014-04-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
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pub_type: 共识发展会议,杂志文章,实务指引
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pub_type: 杂志文章,评审
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
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更新日期:2004-12-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
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更新日期:1994-01-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
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更新日期:1993-07-01 00:00:00