Safety and efficacy of antibiotic prophylaxis in patients undergoing elective laparoscopic cholecystectomy: A systematic review and meta-analysis.

Abstract:

BACKGROUND AND AIM:Owing to persistent controversy regarding the use of routine antibiotic prophylaxis in patients undergoing elective laparoscopic cholecystectomy and the availability of several new randomized controlled trials (RCTs), we conducted an up-to-date meta-analysis to provide the best current evidence. The aim of the article is to evaluate the safety and efficacy of routine antibiotic prophylaxis in low-risk patients undergoing elective laparoscopic cholecystectomy. METHODS:We conducted a comprehensive literature review of the PubMed, Embase, and Cochrane Library databases for RCTs that compared antibiotic prophylaxis versus placebo or no antibiotics in low-risk patients undergoing elective laparoscopic cholecystectomy. RESULTS:The meta-analysis included 21 RCTs (5207 patients). Antibiotic prophylaxis reduced the incidence of surgical site infections (risk ratio [RR] 0.61, 95% confidence interval [CI] 0.45 to 0.82, P = 0.001) and global infections (RR 0.55, 95% CI 0.38 to 0.79, P = 0.001) during hospitalization or after discharge, and postoperative length of hospital stay (weighted mean difference -0.16, 95% CI -0.28 to -0.04, P = 0.008). No adverse events were reported. Subgroup analyses demonstrated that two doses of antibiotic and 3-10 doses of antibiotic significantly reduced the incidence of surgical site infections compared with placebo or no antibiotics (two doses: RR 0.16, 95% CI 0.06-0.47; 3-10 doses: RR 0.46, 95% CI 0.27-0.80), while a single dose of antibiotic administration did not. CONCLUSION:Antibiotic prophylaxis is safe and effective in reducing surgical site infections and global infections during hospitalization or after discharge, and postoperative length of hospital stay in low-risk patients undergoing elective laparoscopic cholecystectomy.

authors

Liang B,Dai M,Zou Z

doi

10.1111/jgh.13246

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

921-8

issue

5

eissn

0815-9319

issn

1440-1746

journal_volume

31

pub_type

杂志文章,meta分析,评审
  • Decreased production of insulin-like growth factor-binding protein (IGFBP)-6 by transfection of colon cancer cells with an antisense IGFBP-6 cDNA construct leads to stimulation of cell proliferation.

    abstract:BACKGROUND:: Previously, we have observed that highly unsaturated dietary (n-3) fatty acids inhibit cell proliferation in conjunction with stimulation of insulin-like growth factor-binding protein (IGFBP)-6 secretion in Caco-2 cells, a human colon carcinoma cell line. METHODS:: To test the converse hypothesis that inh...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2002.02703.x

    authors: Kim EJ,Schaffer BS,Kang YH,Macdonald RG,Park JH

    更新日期:2002-05-01 00:00:00

  • Clinicopathological staging for colorectal cancer: an International Documentation System (IDS) and an International Comprehensive Anatomical Terminology (ICAT).

    abstract::The purpose of tumour staging for colorectal cancer (CRC) is to help define clinical management, facilitate communication between physicians, provide a basis for stratification and analysis of treatment results in prospective studies, and provide some prognostic information for patients and their families. The World C...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1991.tb00867.x

    authors: Fielding LP,Arsenault PA,Chapuis PH,Dent O,Gathright B,Hardcastle JD,Hermanek P,Jass JR,Newland RC

    更新日期:1991-07-01 00:00:00

  • Cryptogenic pyogenic liver abscess as the herald of colon cancer.

    abstract:BACKGROUND AND AIM:Colonic mucosal defects might be a route for bacterial invasion into the portal system, with subsequent hematogenous spread to the liver. We retrospectively investigated the results of colonoscopy and the clinical characteristics of patients with pyogenic liver abscess of colonic origin. METHODS:A t...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2011.06851.x

    authors: Jeong SW,Jang JY,Lee TH,Kim HG,Hong SW,Park SH,Kim SG,Cheon YK,Kim YS,Cho YD,Kim JO,Kim BS,Lee EJ,Kim TH

    更新日期:2012-02-01 00:00:00

  • Case report: radiological and endoscopic management of bile leak following laparoscopic cholecystectomy.

    abstract::Due to the ever increasing popularity of laparoscopic cholecystectomy (LC), many radiologists and gastroenterologists have noticed an epidemic of bile duct injuries due to subsequent complications. We report on five cases of post-LC minor bile duct injuries and document our preliminary experience in their management. ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1997.tb00342.x

    authors: Sammak BM,Yousef BA,Gali MH,al Karawi MA,Mohamed AE

    更新日期:1997-01-01 00:00:00

  • Expression and prognostic significance of gastric-specific annexin A10 in diffuse- and intestinal-type gastric carcinoma.

    abstract:BACKGROUND AND AIMS:Annexin A10 (ANXA10) and its liver-specific short isoform (ANXA10S) had tissue-restricted expression. The downregulation of ANXA10S is correlated with tumor progression and poor prognosis in hepatocellular carcinoma. The aim of the present study was to validate the tissue distribution and explore th...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2010.06480.x

    authors: Lu SH,Chen YL,Shun CT,Lai JN,Peng SY,Lai PL,Hsu HC

    更新日期:2011-01-01 00:00:00

  • Prevention and management of biliary anastomotic stricture in right-lobe living-donor liver transplantation.

    abstract::Biliary strictures can be categorized according to technical factor as anastomotic or nonanastomotic strictures. Biliary anastomotic stricture is a common complication after living-donor liver transplantation, occasionally causing deaths. The two most commonly used methods for biliary anastomosis are duct-to-duct anas...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/jgh.12648

    authors: Chok KS,Lo CM

    更新日期:2014-10-01 00:00:00

  • Natural history of acute hepatitis C.

    abstract::To study the short- and long-term outcomes of acute hepatitis C, three groups of patients were enrolled. Of 26 patients with acute hepatitis C, 18 (69%) maintained HCV viraemia and 8 had cleared virus naturally at 12 months after the onset. Normalization of ALT was seen in all 8 patients with acute resolving hepatitis...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1440-1746.2000.02112.x

    authors: Tanaka E,Kiyosawa K

    更新日期:2000-05-01 00:00:00

  • Comparison between modified wet suction and dry suction technique for endoscopic ultrasound-guided fine-needle biopsy in pancreatic solid lesions.

    abstract:BACKGROUND AND AIM:Although endoscopic ultrasound-guided fine-needle biopsy is widely applied, there is no clear consensus on the optimal biopsy technique. We described a modified wet suction technique (MWEST) with the aim to compare the efficacy and safety between MWEST and the dry suction technique (DST). METHODS:In...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.15371

    authors: Tong T,Tian L,Deng M,Liu Y,Yang Y,Yin H,Long X,Pan S,Yang Z,Luo W,Nie K,Meng X,Xiao M,Wu X,Zhang C,Wang X

    更新日期:2020-12-08 00:00:00

  • Alternative management of anatomical right hemihepatectomy using ligation of inflow and outflow vessels without hilus dissection.

    abstract:BACKGROUND AND AIM:The conventional method of anatomical right hemihepatectomy (ARHH) requires hilus dissection. We report a method without hilus dissection to minimize intraoperative bleeding. METHODS:We retrospectively evaluated data of 107 patients who received ARHH involving ligation of corresponding inflow and ou...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2010.06507.x

    authors: Chen XP,Zhang ZW,Huang ZY,Chen YF,Zhang WG,Qiu FZ

    更新日期:2011-04-01 00:00:00

  • Albumin for cirrhotic patients with extraperitoneal infections: A meta-analysis.

    abstract:BACKGROUND AND AIM:Bacterial infections are among the main causes of death in patients with cirrhosis. While there are unquestionable benefits of using albumin in patients with spontaneous bacterial peritonitis, the benefits of albumin are controversial for those with extraperitoneal infections. The aim was to compare ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,meta分析

    doi:10.1111/jgh.14791

    authors: Leão GS,John Neto G,Jotz RF,Mattos AA,Mattos ÂZ

    更新日期:2019-12-01 00:00:00

  • Combined platelet count with sCD163 and genetic variants optimizes esophageal varices prediction in cirrhotic patients.

    abstract:BACKGROUND AND AIM:Endoscopic screening for esophageal varices (EVs) is expensive and invasive. Besides traditional noninvasive markers, we explore additional candidate markers including portal hypertension serum marker-soluble CD136 (sCD163) and genetic variants of splanchnic vasodilatation and revascularization pathw...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2012.07245.x

    authors: Yang YY,Hou MC,Lin MW,Chen PH,Liao WC,Chu CJ,Lin HC

    更新日期:2013-01-01 00:00:00

  • Health-related quality of life in Chinese patients with primary biliary cirrhosis.

    abstract:BACKGROUND AND AIM:Symptoms and complications of primary biliary cirrhosis (PBC) have been shown to impair patients' health-related quality of life (HRQOL) in the West. We aimed to measure the HRQOL and to determine the factors associated with worse HRQOL among the Chinese PBC patients in Hong Kong. METHODS:Chinese pa...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2007.05092.x

    authors: Wong GL,Law FM,Wong VW,Hui AY,Chan FK,Sung JJ,Chan HL

    更新日期:2008-04-01 00:00:00

  • Survey of consent practices for inpatient colonoscopy and endoscopic retrograde cholangiopancreatography at a tertiary referral center.

    abstract:BACKGROUND:The purpose of the present paper was to determine informed consent practices for inpatient, open-access colonoscopy and endoscopic retrograde cholangiopancreatography (ERCP) at a tertiary referral center. METHODS:A two-part prospective study incorporating (i) an audit of consent practices for colonoscopy an...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2006.04152.x

    authors: Seow CH,Leber JM,Ee HC,Yusoff IF

    更新日期:2006-08-01 00:00:00

  • Which patients benefit from hemodialysis therapy in hepatorenal syndrome?

    abstract:BACKGROUND AND AIM:Hepatorenal syndrome (HRS) occurs in patients with advanced liver cirrhosis and has a poor outcome. The aim of the present study was to investigate which patients with HRS are likely to benefit from hemodialysis. METHODS:Data were collected prospectively from 30 patients with Child-Pugh C liver cirr...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2004.03471.x

    authors: Witzke O,Baumann M,Patschan D,Patschan S,Mitchell A,Treichel U,Gerken G,Philipp T,Kribben A

    更新日期:2004-12-01 00:00:00

  • Spleen stiffness measurement using Fibroscan for the noninvasive assessment of esophageal varices in liver cirrhosis patients.

    abstract:BACKGROUND AND AIM:Splenomegaly in a common finding in liver cirrhosis that should determine changes in the spleen's density because of portal and splenic congestion and/or because of tissue hyperplasia and fibrosis. These changes might be quantified by elastography, so the aim of the study was to investigate whether s...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2010.06325.x

    authors: Stefanescu H,Grigorescu M,Lupsor M,Procopet B,Maniu A,Badea R

    更新日期:2011-01-01 00:00:00

  • Epidemiology of alcoholic and nonalcoholic fatty liver disease in China.

    abstract::The prevalence of patients presenting with fatty liver disease (FLD) in China has approximately doubled over the past two decades. At present, FLD, which is typically diagnosed by imaging, is highly prevalent (≈ 27% urban population) in China and is mainly related to obesity and metabolic syndrome (MetS). However, the...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/jgh.12036

    authors: Fan JG

    更新日期:2013-08-01 00:00:00

  • A pilot study to evaluate a new combination therapy for gastric ulcer: Helicobacter pylori eradication therapy followed by gastroprotective treatment with rebamipide.

    abstract:BACKGROUND AND AIM:Controversies remain over the need for antiulcer treatment following 1-week eradication triple therapy for Helicobacter pylori-positive peptic ulcers. The usefulness of combination therapy for gastric ulcers in Japanese patients, which consists of H. pylori eradication followed by gastroprotective th...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1440-1746.2005.04191.x

    authors: Terano A,Arakawa T,Sugiyama T,Yoshikawa T,Haruma K,Asaka M,Shimosegawa T,Sakaki N,Ishii H,Sakamoto C,Takahashi S,Kinoshita Y,Fujioka T,Kobayashi K

    更新日期:2006-01-01 00:00:00

  • Thiopurines prevented surgical recurrence in patients with Crohn's disease after intestinal resection: Strategy based on risk stratification.

    abstract:BACKGROUND AND AIM:Thiopurines (TPs) are effective in reducing clinical and endoscopic recurrence in postoperative patients with Crohn's disease (CD). However, whether TPs could prevent surgical recurrence (SR) remains unknown. We aimed to explore whether TPs could prevent SR and identify risk factors associated with S...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.13922

    authors: Guo J,Chen BL,Chen ZH,Luo XP,Qiu Y,Zhang SH,Feng R,He Y,Zeng ZR,Song XM,Ben-Horin S,Mao R,Chen MH

    更新日期:2018-03-01 00:00:00

  • Prevalence of enteric pathogens among community based asymptomatic individuals.

    abstract:BACKGROUND AND AIMS:The objective of this study was to describe the prevalence of pathogenic microorganisms in asymptomatic individuals in a community study in Melbourne, Australia. METHODS:The study population was a subset of 2803 individuals participating in the Water Quality Study; a community based randomized tria...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1440-1746.2000.02089.x

    authors: Hellard ME,Sinclair MI,Hogg GG,Fairley CK

    更新日期:2000-03-01 00:00:00

  • Thrombomodulin expression of sinusoidal endothelial cells in chronic viral hepatitis.

    abstract::The expression of thrombomodulin on sinusoidal endothelial cells was studied using the immuno-peroxidase method and both light and electron microscopy in patients with chronic viral hepatitis (type B: four cases; type C: 28 cases). Thrombomodulin was found on sinusoidal endothelial cells, especially on the surface in ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1995.tb01805.x

    authors: Zeniya M,Fukata H,Toda G

    更新日期:1995-01-01 00:00:00

  • Ultrasound-guided fine needle aspiration biopsy of portal vein thrombosis in liver cirrhosis: results in 15 patients.

    abstract::Between 1988 and 1992 ultrasound-guided fine needle aspiration biopsies of thromboses in the main branches of the portal vein were carried out in 15 patients with liver cirrhosis. The aims of the study were to evaluate the usefulness, feasibility and diagnostic accuracy of this procedure in cirrhotics with known or su...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1995.tb01367.x

    authors: De Sio I,Castellano L,Calandra M,Romano M,Persico M,Del Vecchio-Blanco C

    更新日期:1995-11-01 00:00:00

  • Iron-deficiency anemia complicating AL amyloidosis with recurrent small bowel pseudo-obstruction and hindgut sparing.

    abstract::AL amyloidosis complicating multiple myeloma is rare but well recognized. Endoscopic appearances of amyloid in the gastrointestinal tract can, however, be highly variable. Macroscopic appearances of the duodenum can range from scalloping (often seen in celiac disease) to that of duodenitis; erosive disease, frank ulce...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2002.02719.x

    authors: Hurlstone DP

    更新日期:2002-05-01 00:00:00

  • Increased neutrophil chemotaxis in obstructive jaundice: an in vitro experiment in rats.

    abstract:BACKGROUND AND AIMS:Changes in neutrophil functions in obstructive jaundice have been poorly understood. An in vitro experimental study was performed to evaluate the effect of obstructive jaundice on the functions of macrophages (secretion of neutrophil chemoattractants) and neutrophils (chemotaxis and superoxide anion...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.1999.01880.x

    authors: Tsuji K,Kubota Y,Yamamoto S,Yanagitani K,Amoh Y,Takaoka M,Ogura M,Kin H,Inoue K

    更新日期:1999-05-01 00:00:00

  • Clinical significance of hiatal hernia in the development of gastroesophageal reflux after distal gastrectomy for cancer of the stomach.

    abstract:BACKGROUND AND AIMS:The relationship between gastroesophageal reflux disease and sliding hernia is controversial, especially following distal partial gastrectomy in patients with gastric cancer. The aim of this study was to examine the relationship between gastroesophageal reflux disease and sliding hernia of the esoph...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2006.04135.x

    authors: Fujiwara Y,Nakao K,Inoue T,Koishi K,Nishio Y,Yagyu R,Nakagawa K,Yamamura T

    更新日期:2006-07-01 00:00:00

  • Extended indication of endoscopic resection for mucosal early gastric cancer: analysis of a single center experience.

    abstract:BACKGROUND:Endoscopic resection (ER) has become an important therapeutic option for early gastric cancer (EGC). Some investigators have suggested that this indication should be extended. We aimed to compare the extended indication of ER for intramucosal EGC based on data from a large, single-center study. METHODS:We a...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2010.06611.x

    authors: Chung JW,Jung HY,Choi KD,Song HJ,Lee GH,Jang SJ,Park YS,Yook JH,Oh ST,Kim BS,Kim JH

    更新日期:2011-05-01 00:00:00

  • Cyclo-oxygenase-2 inhibitors suppress epithelial cell kinetics and delay gastric wound healing in rats.

    abstract:BACKGROUND AND AIMS:The present study examined the effects of NS-398, a specific cyclo-oxygenase-2 inhibitor, on gastric mucosal cell kinetics and gastric wound healing following acid-induced injury. METHODS:Male Sprague-Dawley rats were fasted for 24 h and then 0.6 mol/L hydrochloric acid (HCl; 1 mL) was administered...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2000.02242.x

    authors: Sun WH,Tsuji S,Tsujii M,Gunawan ES,Sawaoka H,Kawai N,Iijima H,Kimura A,Kakiuchi Y,Yasumaru M,Sasaki Y,Kawano S,Hori M

    更新日期:2000-07-01 00:00:00

  • Prospective evaluation of a clinical guideline recommending early patients discharge in bleeding peptic ulcer.

    abstract:BACKGROUND AND AIM:To validate an early discharge policy in patients admitted with upper gastrointestinal bleeding (UGIB) due to ulcers. METHODS:Patients with gastroduodenal ulcer or erosive gastritis/duodenitis were included in a previous study aiming to develop a practice guideline for early discharge of patients wi...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2010.06374.x

    authors: Chaparro M,Barbero A,Martín L,Esteban C,Espinosa L,de la Morena F,Sánchez A,Martín I,Santander C,Moreno-Otero R,Gisbert JP

    更新日期:2010-09-01 00:00:00

  • Indocyanine green retention test in cirrhosis and portal hypertension: Accuracy and relation to severity of disease.

    abstract:BACKGROUND AND AIMS:Patients with cirrhosis and portal hypertension often develop complications relating to hepatic excretory dysfunction. The standard measurement of the hepatic excretion is the constant infusion indocyanine green clearance (ICGCI ) technique. The ICG 15-min retention test (ICG-r15) is faster, more pa...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.14470

    authors: Møller S,la Cour Sibbesen E,Madsen JL,Bendtsen F

    更新日期:2019-06-01 00:00:00

  • Effects of terlipressin on systemic, hepatic and renal hemodynamics in patients with cirrhosis.

    abstract:BACKGROUND AND AIM:Terlipressin has been shown to be effective in the management of hepatorenal syndrome. However, how terlipressin exerts its effect on the renal artery is unknown. The aim of the present study was to assess the effects of terlipressin on systemic, hepatic and renal hemodynamics in cirrhosis. METHODS:...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1440-1746.2009.05873.x

    authors: Narahara Y,Kanazawa H,Taki Y,Kimura Y,Atsukawa M,Katakura T,Kidokoro H,Harimoto H,Fukuda T,Matsushita Y,Nakatsuka K,Sakamoto C

    更新日期:2009-11-01 00:00:00

  • Effect of Helicobacter pylori eradication on gastroesophageal function.

    abstract:BACKGROUND:To elucidate the cause of possible occurrence of reflux esophagitis after Helicobacter pylori eradication, gastric and esophageal function among H. pylori infected Japanese patients were evaluated both before and after eradication therapy. METHODS:Nine H. pylori-positive patients were studied before and 6 m...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2003.03301.x

    authors: Tanaka I,Tatsumi Y,Kodama T,Kato K,Fujita S,Mitsufuji S,Kashima K

    更新日期:2004-03-01 00:00:00