Epidemiology of alcoholic and nonalcoholic fatty liver disease in China.

abstract：BACKGROUND AND AIMS:The present study examined the effects of NS-398, a specific cyclo-oxygenase-2 inhibitor, on gastric mucosal cell kinetics and gastric wound healing following acid-induced injury. METHODS:Male Sprague-Dawley rats were fasted for 24 h and then 0.6 mol/L hydrochloric acid (HCl; 1 mL) was administered...

journal_title：Journal of gastroenterology and hepatology

authors： Sun WH,Tsuji S,Tsujii M,Gunawan ES,Sawaoka H,Kawai N,Iijima H,Kimura A,Kakiuchi Y,Yasumaru M,Sasaki Y,Kawano S,Hori M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND AIM:Immunization against hepatitis B virus (HBV) infection is recommended in patients with inflammatory bowel disease (IBD), particularly in those under immunosuppressive therapy. Limited data are available about IBD patient's response to HBV vaccination. We assessed the response rate to HBV vaccination ...

journal_title：Journal of gastroenterology and hepatology

authors： Andrade P,Santos-Antunes J,Rodrigues S,Lopes S,Macedo G

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND AIM:Symptoms and complications of primary biliary cirrhosis (PBC) have been shown to impair patients' health-related quality of life (HRQOL) in the West. We aimed to measure the HRQOL and to determine the factors associated with worse HRQOL among the Chinese PBC patients in Hong Kong. METHODS:Chinese pa...

journal_title：Journal of gastroenterology and hepatology

authors： Wong GL,Law FM,Wong VW,Hui AY,Chan FK,Sung JJ,Chan HL

更新日期：2008-04-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNAs of 19-23 nucleotides that negatively regulate gene expression through binding to the 3'-untranslated regions of target messenger RNAs (mRNAs). Although the miRNA family constitutes only a minor fraction of the human genome, they hold fundamental importance in diverse physio...

journal_title：Journal of gastroenterology and hepatology

authors： Law PT,Wong N

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND AIM:To guide selection of optimal screening strategies for advanced colorectal neoplasia (ACRN), we evaluated the screening performances of sigmoidoscopy, fecal immunochemical test (FIT), and the Asia-Pacific Colorectal Screening (APCS) system, as well as combinations of these techniques. METHODS:We rev...

journal_title：Journal of gastroenterology and hepatology

authors： Jung YS,Park CH,Kim NH,Park JH,Park DI,Sohn CI

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Hyposplenism has been described in patients with alcoholic cirrhosis (AC). However, no data are available regarding hyposplenism in patients with non-alcoholic cirrhosis (NAC) and other forms of portal hypertension such as extrahepatic portal venous obstruction (EHPVO). The aim is to study the splen...

journal_title：Journal of gastroenterology and hepatology

authors： Satapathy SK,Narayan S,Varma N,Dhiman RK,Varma S,Chawla Y

更新日期：2001-09-01 00:00:00

abstract：:Following partial hepatectomy (PH), there is a rapid and highly orchestrated series of biochemical events which occur prior to cellular proliferation. Some of these events are presumably intimately linked with the eventual regeneration of the liver, whereas others are likely to be stress related or required for the co...

journal_title：Journal of gastroenterology and hepatology

authors： Brenner DA

更新日期：1998-09-01 00:00:00

abstract：:Low-dose aspirin (ASA) has emerged as one of the most important causes of peptic ulcer bleeding in developed countries. Among the risk factors of ASA-associated ulcer bleeding, Helicobacter pylori infection is one of the few that is treatable. Recent evidence showed that among patients with a history of ASA-associated...

journal_title：Journal of gastroenterology and hepatology

authors： Chan FK

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND AIM:This study examined the effects of adrenergic blockade on muscle wasting and expression of the ubiquitin-proteasome system, tumor necrosis factor-α (TNF-α) and its signaling pathways in skeletal muscles of cirrhotic rats. METHODS:Cirrhosis was induced by bile duct ligation in adult male Sprague-Dawl...

journal_title：Journal of gastroenterology and hepatology

authors： Lin SY,Wang YY,Chuang YH,Chen CJ

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Cyanoacrylate injection is highly effective and is regarded as the treatment of choice in bleeding gastric varices in Europe, but intravenous injection of cyanoacrylate is not allowed in the USA and Japan because it may cause embolisms in other organs. Accordingly, we developed a new endoscopic combined trea...

journal_title：Journal of gastroenterology and hepatology

authors： Yoshida T,Harada T,Shigemitsu T,Takeo Y,Miyazaki S,Okita K

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:In order to evaluate the prophylactic impact of sclerotherapy of small varices in patients with cirrhosis and no endoscopic signs suggesting risk of haemorrhage, a randomized clinical trial was performed. METHODS:Seventy-one hospitalized patients met the inclusion criteria of diagnosis of cirrhosis with no ...

journal_title：Journal of gastroenterology and hepatology

authors： Strauss E,Ribeiro MF,Albano A,Honain NZ,Maffei RA Jr,Caly WR

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND AIM:Epithelial-mesenchymal transition (EMT) of biliary epithelial cells (BECs) plays an important role in biliary fibrosis. This study investigated the effects of simvastatin on the lipopolysaccharide (LPS)-induced EMT and related signal pathways in BECs. METHODS:Biliary epithelial cells were exposed to...

journal_title：Journal of gastroenterology and hepatology

authors： Kim Y,Lee EJ,Jang HK,Kim CH,Kim DG,Han JH,Park SM

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND AND AIM:The introduction of sofosbuvir has revolutionized the treatment of chronic hepatitis C. This study was planned to observe whether the efficacy and tolerability of sofosbuvir-based regimens demonstrated in phase 3 clinical trial results translate into real-life clinical practice. METHODS:This prospec...

journal_title：Journal of gastroenterology and hepatology

authors： Sood A,Midha V,Mahajan R,Narang V,Mehta V,Wander P,Sharma S,Kaur K,Singh D

更新日期：2017-04-01 00:00:00

abstract：:Better understanding of hepatitis B virus (HBV) replication and the natural history and immunopathogenesis of chronic hepatitis B, together with the introduction of effective agents with different mechanisms of action, is the basis for better therapeutic strategies against chronic hepatitis B. Substantial experience h...

journal_title：Journal of gastroenterology and hepatology

authors： Liaw YF

更新日期：2002-04-01 00:00:00

abstract：:One of the characteristic features of the majority of pancreatic ductal adenocarcinomas is an abundant desmoplastic/stromal reaction. Until recently, this stroma had received little attention from researchers studying the pathogenesis of pancreatic cancer, with most of the research focus resting on the biology of tumo...

journal_title：Journal of gastroenterology and hepatology

authors： Apte MV,Wilson JS

更新日期：2012-03-01 00:00:00

abstract：:The low Fermentable Oligosaccharides, Disaccharides, and Monosaccharides And Polyols (FODMAP) diet has been described, evaluated, and found efficacious for the treatment of patients with irritable bowel syndrome primarily in Western countries. The aim of this review was to address the applicability of this diet to Sou...

journal_title：Journal of gastroenterology and hepatology

authors： Hewawasam SP,Iacovou M,Muir JG,Gibson PR

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Interstitial cells of Cajal (ICCs), which express c-Kit receptor tyrosine kinase (KIT), play an important role in gastrointestinal motility. Loss of ICCs likely contributes to diabetic gastrointestinal motility disorder, however, the mechanism of attrition remains unknown. Here, we test the hypothesis that t...

journal_title：Journal of gastroenterology and hepatology

authors： Li Y,Kojima H,Fujino K,Matsumura K,Katagi M,Urabe H,Chan L,Eguchi Y,Zhao L,Kimura H

更新日期：2011-06-01 00:00:00

abstract：:A case-control study was conducted to evaluate the efficacy of ursodeoxycholic acid (UDCA) in the treatment of Chinese patients with chronic hepatitis C. Patients who failed to have sustained responses to interferon (IFN) therapy, refused to take IFN or were unsuitable for IFN treatment were enrolled into this study. ...

journal_title：Journal of gastroenterology and hepatology

authors： Lu CL,Chan CY,Hwang SJ,Lu RH,Lee SD

更新日期：1995-07-01 00:00:00

abstract：:Although the incidence of bleeding from gastric varices is relatively low (10%-36%), the bleeding is massive once it has occurred and it increases the patient's mortality. The management of esophageal variceal bleeding is highly differentiated with several effective treatments available. In contrast, bleeding from gas...

journal_title：Journal of gastroenterology and hepatology

authors： Hashizume M,Akahoshi T,Tomikawa M

更新日期：2011-01-01 00:00:00

abstract：:Brief periods of tissue ischemia produced tissue resistance to prolonged ischemia and reperfusion, a phenomenon called ischemic preconditioning. The mechanisms of ischemic preconditioning were examined in a rat warm ischemia-reperfusion model as well as the effect of ischemic preconditioning on liver regeneration. Isc...

journal_title：Journal of gastroenterology and hepatology

authors： Arai M,Tejima K,Ikeda H,Tomiya T,Yanase M,Inoue Y,Nagashima K,Nishikawa T,Watanabe N,Omata M,Fujiwara K

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND AND AIM:Intubation of the terminal ileum (TI) demonstrates a complete colonoscopy, but its clinical value during screening exams is unknown. We aimed to determine whether TI intubation during screening colonoscopy is associated with colonoscopy quality measures or identifies subclinical pathology. METHODS:W...

journal_title：Journal of gastroenterology and hepatology

authors： Leiman DA,Jawitz NG,Lin L,Wood RK,Gellad ZF

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND AIM:At the same time that Helicobacter pylori prevalence is declining in Western countries, immigrants from developing countries with high H. pylori prevalence have settled in Western urban areas. Actual epidemiological data on H. pylori in a migrant community may help in realizing a more selective appro...

journal_title：Journal of gastroenterology and hepatology

authors： den Hollander WJ,Holster IL,den Hoed CM,van Deurzen F,van Vuuren AJ,Jaddoe VW,Hofman A,Perez Perez GI,Blaser MJ,Moll HA,Kuipers EJ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) can now provide a cytopathological diagnosis of underlying pancreatic malignancy with higher success rates than endoscopic retrograde pancreatography (ERP). To determine the significance of EUS-FNA for the diagnosis of pancreatic mass without...

journal_title：Journal of gastroenterology and hepatology

authors： Wakatsuki T,Irisawa A,Bhutani MS,Hikichi T,Shibukawa G,Takagi T,Yamamoto G,Takahashi Y,Yamada Y,Watanabe K,Obara K,Suzuki T,Sato Y

更新日期：2005-11-01 00:00:00

abstract：AIM:To investigate the factors affecting the outcome of fulminant hepatic failure (FHF) in children in relation to hepatitis B virus (HBV) infection. METHODS:Retrospective review of a total of 94 cases (61 males and 33 females, aged from 1 month to 15 years) recruited from nine tertiary referral centers in Taiwan from...

journal_title：Journal of gastroenterology and hepatology

authors： Chan PC,Chen HL,Kong MS,Huang FC,Lee HC,Lin CC,Liu CC,Lee IH,Wu TC,Wu SF,Ni YH,Hsu HY,Chang MH

更新日期：2005-08-01 00:00:00

abstract：:Affecting one fourth of the global population, non-alcoholic fatty liver disease (NAFLD) is the commonest chronic liver disorder. It encompasses the simple liver fat accumulation to more progressive steatosis, inflammation, and fibrosis characterized as non-alcoholic steatohepatitis (NASH) and in some cases cirrhosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Chrysavgis L,Papatheodoridi AM,Chatzigeorgiou A,Cholongitas E

更新日期：2020-07-27 00:00:00

abstract：:The aim of this study was to determine the distribution of hepatitis C virus (HCV) genotypes in Australian patients with hepatitis C and to identify factors associated with particular genotypes. Serum isolates of HCV-RNA were genotyped using a commercial oligonucleotide hybridization (line probe) assay. Relationships ...

journal_title：Journal of gastroenterology and hepatology

authors： Kaba S,Dutta U,Byth K,Crewe EB,Khan MH,Coverdale SA,Lin R,Liddle C,Farrell GC

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Although there is strong implication that retinoids regulate Ito cell proliferation and collagen synthesis, results from in vivo studies on the relationship between vitamin A and liver fibrosis are conflicting. The present study focuses on the role of vitamin A in carbon tetrachloride (CCl4)-induced fibrosis...

journal_title：Journal of gastroenterology and hepatology

authors： Vollmar B,Heckmann C,Richter S,Menger MD

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND AIM:Familial adenomatous polyposis (FAP) is the most common adenomatous polyposis syndrome. Patients with FAP are screened for germline mutations of two genes, APC and MUTYH. However, limited data exist on the clinical characterization and genotypic spectrum of FAP in China. This study was aimed to deter...

journal_title：Journal of gastroenterology and hepatology

authors： Li N,Kang Q,Yang L,Zhao XJ,Xue LJ,Wang X,Li AQ,Li CG,Sheng JQ

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND AND AIM:The role of octamer-binding transcription factor 4 (Oct4) has been implicated in the clinical prognosis of various kinds of digestive system cancers, but the results remain controversial. The purpose of this meta-analysis is to assess the potential role of Oct4 as a prognostic marker in digestive sys...

journal_title：Journal of gastroenterology and hepatology

authors： Chen Z,Zhang L,Zhu Q,Wang X,Wu J,Wang X

更新日期：2017-03-01 00:00:00

abstract：:The subjects of this study were 151 patients (69 males and 82 females) who underwent examination and liver biopsy owing to liver dysfunction in an epidemic area with hepatitis C. Second generation hepatitis C virus antibody (HCV Ab) was positive in 116 (76.8%) of 151 cases. HCV-RNA was detected in 120 (79.5%) by polym...

journal_title：Journal of gastroenterology and hepatology

authors： Yamada M,Fukuda Y,Imoto M,Koyama Y,Hayakawa T,Takayama T,Nagura H

更新日期：1994-11-01 00:00:00