Dangerous liaisons: pancreatic stellate cells and pancreatic cancer cells.

abstract：BACKGROUND AND AIMS:Hyposplenism has been described in patients with alcoholic cirrhosis (AC). However, no data are available regarding hyposplenism in patients with non-alcoholic cirrhosis (NAC) and other forms of portal hypertension such as extrahepatic portal venous obstruction (EHPVO). The aim is to study the splen...

journal_title：Journal of gastroenterology and hepatology

authors： Satapathy SK,Narayan S,Varma N,Dhiman RK,Varma S,Chawla Y

更新日期：2001-09-01 00:00:00

abstract：:Sensitive and specific enzyme-linked immunosorbent assays (ELISA) were developed to detect separately the binding of polymerized human serum albumin (PHSA) to its antibody (A-PHSA) and to the hepatitis B surface antigen (HBsAg). A-PHSA was not detected in normal serum, whereas more than one-third to about half of sera...

journal_title：Journal of gastroenterology and hepatology

authors： Dash S,Panda SK,Nayak NC

更新日期：1990-01-01 00:00:00

abstract：:The most frequent benign tumours of the liver include haemangioma, liver cell adenoma and focal nodular hyperplasia. Patients may undergo hepatic resection because of a preoperative diagnosis of malignancy or uncertainty in diagnosis despite an extensive work-up. ...

journal_title：Journal of gastroenterology and hepatology

authors： Chen MF

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND AND AIM:Simultaneous and metachronous head and neck cancers are likely to develop in patients with current or previous esophageal cancer. The Valsalva maneuver facilitates the visualization of the hypopharyngeal area during endoscopic observation, but it requires transnasal endoscopy. We developed a novel Va...

journal_title：Journal of gastroenterology and hepatology

authors： Iwatsubo T,Ishihara R,Nakagawa K,Ohmori M,Iwagami H,Matsuno K,Inoue S,Nakahira H,Matsuura N,Shichijo S,Maekawa A,Kanesaka T,Yamamoto S,Takeuchi Y,Higashino K,Uedo N,Higuchi K

更新日期：2019-08-01 00:00:00

abstract：:Acid-sensing pathways, which trigger mucosal defense mechanisms in response to luminal acid, involve the rapid afferent-mediated "capsaicin pathway" and the sustained "prostaglandin (PG) pathway." Luminal acid quickly increases protective PG synthesis and release from epithelia, although the mechanism by which luminal...

journal_title：Journal of gastroenterology and hepatology

authors： Akiba Y,Kaunitz JD

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis E virus (HEV) infection is endemic in several developing countries. Clinical manifestations of this infection vary widely from asymptomatic infection to uncomplicated acute viral hepatitis and fulminant hepatic failure. The pathogenesis of this disease and the reason of varying disease seve...

journal_title：Journal of gastroenterology and hepatology

authors： Srivastava R,Aggarwal R,Sachdeva S,Alam MI,Jameel S,Naik S

更新日期：2011-02-01 00:00:00

abstract：:Hepatitis B virus (HBV) infection remains a major issue among dialysis patients. It is associated with a high risk of hepatic complication. The liver disease runs a unique clinical course in dialysis patients, as it can progress with modest hepatic inflammation and prominent fibrosis. The conventional cut-off level of...

journal_title：Journal of gastroenterology and hepatology

authors： Wong PN,Fung TT,Mak SK,Lo KY,Tong GM,Wong Y,Loo CK,Lam EK,Wong AK

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND AIM:Glypican-3 (GPC3) expression is correlated with poor prognosis and progression in hepatocellular carcinoma (HCC). HCC progression can be associated with the differentiation status of tumor cell before malignant transformation. Our aim was to investigate the dynamic expression of GPC3 during tumor cel...

journal_title：Journal of gastroenterology and hepatology

authors： Xue R,Feng J,Meng Q,Lv F,Zhu Y,Yu H,Zhang S,Song C,Sun L,Yue Z,Feng S,Che R,Xiang Q,Jing X

更新日期：2017-08-01 00:00:00

abstract：:Following partial hepatectomy (PH), there is a rapid and highly orchestrated series of biochemical events which occur prior to cellular proliferation. Some of these events are presumably intimately linked with the eventual regeneration of the liver, whereas others are likely to be stress related or required for the co...

journal_title：Journal of gastroenterology and hepatology

authors： Brenner DA

更新日期：1998-09-01 00:00:00

abstract：:A series of 51 patients with achalasia of the oesophagus treated by pneumatic dilatation between 1980 and 1988 is reported. Treatment was assessed as effective (no or minimal dysphagia) in 78% of patients, followed for a mean of 30 months. Thirty-four patients required only one dilatation and only two patients had mor...

journal_title：Journal of gastroenterology and hepatology

authors： Prewett EJ,Desmond PV,Breen KJ

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND AND AIM:We aimed to investigate the ability of fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET)/computed tomography (CT) to detect synchronous neoplasms, specifically obstructive colorectal cancer (CRC) and CRC in the proximal colon and to suggest a management strategy based on FDG PET/CT fi...

journal_title：Journal of gastroenterology and hepatology

authors： Kim WS,Lee HS,Lee JM,Kwak MS,Hwang SW,Park SH,Yang DH,Kim KJ,Myung SJ,Yang SK,Byeon JS

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND AND AIM:Although the esophagus is a common site of opportunistic infection in AIDS patients, little is known about the impact of HIV as well as opportunistic infection in the esophageal mucosa. Our aim is to analyze the esophageal immune profile in HIV+ patients with different immunological status with and w...

journal_title：Journal of gastroenterology and hepatology

authors： Werneck-Silva AL,Pagliari C,Patzina RA,Takakura CFH,Duarte MI

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Biliary disease is one of the most common causes of acute pancreatitis in adults; however, this cause and outcome in children have rarely been described in the literature. Therefore, the present study was conducted to evaluate the role of biliary disease as a cause of acute pancreatitis in children....

journal_title：Journal of gastroenterology and hepatology

authors： Choi BH,Lim YJ,Yoon CH,Kim EA,Park YS,Kim KM

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND AIM:The presence of spur-cell anemia (SCA) is due to lipid disturbances of the erythrocyte membrane and may develop in patients with advanced liver cirrhosis. The accurate predicting value of SC for survival has not been clarified. The aim of this study was to evaluate SCA as a prognostic indicator in pa...

journal_title：Journal of gastroenterology and hepatology

authors： Alexopoulou A,Vasilieva L,Kanellopoulou T,Pouriki S,Soultati A,Dourakis SP

更新日期：2014-04-01 00:00:00

abstract：:To ascertain whether acid inhibition or Helicobacter pylori (HP) colonization is the decisive factor in the healing of duodenal ulcer, we treated 54 patients with famotidine and carried out long-term follow-up. Helicobacter pylori colonization was found in 70.4% of patients before treatment. There were no differences ...

journal_title：Journal of gastroenterology and hepatology

authors： Lai KH,Chang FY,Tsay SH,Lu LC,Cheng JT,Jeng SS,Wu TC,Ng WW,Jeng JS,Lee SD

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND AND AIM:In Japan, peptic ulcer disease (PUD) is treated clinically with a combination of a mucosal protectant and acid suppressants, but there is scant information regarding the effects of these drugs on normal gastric mucus cells. In the present study, the effects of co-administration of methylmethionine su...

journal_title：Journal of gastroenterology and hepatology

authors： Ichikawa T,Ito Y,Saegusa Y,Iwai T,Goso Y,Ikezawa T,Ishihara K

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND AIM:In hilar cholangiocarcinoma, an accurate assessment of preoperative resectability is important to optimize surgical resection. We investigated the accuracy of the combination of intraductal ultrasonography (IDUS) and percutaneous transhepatic cholangioscopy (PTCS) for evaluating longitudinal extent i...

journal_title：Journal of gastroenterology and hepatology

authors： Kim HM,Park JY,Kim KS,Park MS,Kim MJ,Park YN,Bang S,Song SY,Chung JB,Park SW

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Slow waves play an important role in controlling the frequency and propagation of gastrointestinal contractions. However, mechanisms involved in the modulation of slow wave activity in vivo are still unclear. In this study, the roles of different neurotransmitters in the regulation of gastrointestin...

journal_title：Journal of gastroenterology and hepatology

authors： Liu S,Xu J,Chen JDz

更新日期：2007-07-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the major cancers in the world. There is a striking variation in HCC incidence rates between various countries, with a highest-to-lowest ratio of 112.5 for males and 54.7 for females. The high-risk populations are clustered in sub-Saharan Africa and eastern Asia. The male-to-fe...

journal_title：Journal of gastroenterology and hepatology

authors： Chen CJ,Yu MW,Liaw YF

更新日期：1997-10-01 00:00:00

abstract：:Following the development of tests for hepatitis C virus and hepatitis E virus infection, it became clear that there remained cases of hepatitis that were non-A-E. Such cases provided impetus for the search for additional hepatitis viruses and, by using molecular techniques, several candidates were identified. An ente...

journal_title：Journal of gastroenterology and hepatology

authors： Bowden S

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the potential role of three-dimensional (3-D) conformal radiotherapy (RT) in treatment of unresectable hepatocellular carcinoma (HCC). METHODS:Thirteen patients were included in this study, which was conducted between 1993 and 1996. Nine patients (group A) were tre...

journal_title：Journal of gastroenterology and hepatology

authors： Cheng SH,Lin YM,Chuang VP,Yang PS,Cheng JC,Huang AT,Sung JL

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND AND AIM:CDKN2A/CDKN2B locus on 9p21 is reported to be associated with various diseases, including cancer and cardiovascular and inflammatory diseases. Significant downregulation of CDKN2B-AS1 in inflamed colon tissue of inflammatory bowel disease (IBD) cases was reported in Europeans. This study aimed to con...

journal_title：Journal of gastroenterology and hepatology

authors： Lee HS,Lee SB,Kim BM,Hong M,Jung S,Hong J,Baek J,Han B,Oh SH,Kim KM,Park SH,Yang SK,Ye BD,Song K

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatitis C virus (HCV)-infected patients who responded to interferon (IFN) treatment with clearance of serum HCV RNA may rarely develop hepatocellular carcinoma (HCC). The aim of the present study was to elucidate the risk factors for liver carcinogenesis among such patients. METHODS:In total, 126 ...

journal_title：Journal of gastroenterology and hepatology

authors： Tokita H,Fukui H,Tanaka A,Kamitsukasa H,Yagura M,Harada H,Okamoto H

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND AND AIM:To validate an early discharge policy in patients admitted with upper gastrointestinal bleeding (UGIB) due to ulcers. METHODS:Patients with gastroduodenal ulcer or erosive gastritis/duodenitis were included in a previous study aiming to develop a practice guideline for early discharge of patients wi...

journal_title：Journal of gastroenterology and hepatology

authors： Chaparro M,Barbero A,Martín L,Esteban C,Espinosa L,de la Morena F,Sánchez A,Martín I,Santander C,Moreno-Otero R,Gisbert JP

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The relationship between visceral adiposity and the incidence of functional dyspepsia (FD) has not yet been studied. The purpose of the present study is to evaluate the association between visceral adiposity and the risk of FD. METHODS:This is a case-control study that compares the abdominal adipose tissue ...

journal_title：Journal of gastroenterology and hepatology

authors： Jung JG,Yang JN,Lee CG,Choi SH,Kwack WG,Lee JH,Kang HW

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND AIM:The effect of solid debris on walled-off necrosis (WON) drainage remains unknown. Our study evaluated the role of solid debris in endoscopic ultrasound (EUS)-guided drainage of WON compared lumen-apposing metal stent (LAMS) with double-pigtail plastic stent (DPPS). METHODS:We retrospectively evaluat...

journal_title：Journal of gastroenterology and hepatology

authors： Zhu H,Xie P,Wang Y,Jin Z,Li Z,Du Y

更新日期：2020-05-04 00:00:00

abstract：BACKGROUND:Collagenous sprue (CS) is a rare form of enteropathy that had been reported to be associated with celiac disease (CD) and collagenous colitis (CC). The aim of our study was to compare the clinical features, treatments, and outcomes of CS, CD, and CC. METHODS:All patients with histologic diagnosis of CS, CD,...

journal_title：Journal of gastroenterology and hepatology

authors： Lan N,Shen B,Yuan L,Liu X

更新日期：2017-01-01 00:00:00

abstract：:Infiltrating leucocytes are activated to generate reactive oxygen species or to produce several molecules in inflamed colonic mucosa. To clarify the phenotypical and functional properties of activating cells in colitic mucosa, 23 patients with ulcerative colitis and 13 controls were studied using a combined method for...

journal_title：Journal of gastroenterology and hepatology

authors： Oshitani N,Sawa Y,Hara J,Adachi K,Nakamura S,Matsumoto T,Arakawa T,Kuroki T

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Sepsis is an important complication and cause of morbidity and mortality in acute pancreatitis (AP). The source of sepsis may be infected pancreatic and peripancreatic collections and/or necrosis or extrapancreatic including infections in the bloodstream or respiratory and urinary tracts. We studied...

journal_title：Journal of gastroenterology and hepatology

authors： Rao C,Bhasin DK,Rana SS,Gupta R,Gautam V,Singh K

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND AND AIM:Estimates suggest that in Asia, more than 31 million individuals have hepatitis C virus infection. The present analysis was conducted to assess the efficacy and safety of elbasvir/grazoprevir in Asian participants enrolled in the elbasvir/grazoprevir phase 2/3 clinical trials. METHODS:This is an int...

journal_title：Journal of gastroenterology and hepatology

authors： Wei L,Kumada H,Perumalswami PV,Tanwandee T,Cheng W,Heo J,Cheng PN,Hwang P,Mu SM,Zhao XM,Asante-Appiah E,Caro L,Hanna GJ,Robertson MN,Haber BA,Talwani R

更新日期：2019-09-01 00:00:00