High rate of mixed genotypes of hepatitis C virus in patients of an epidemic area in Japan.

abstract：BACKGROUND AND AIM:The high-mobility group box 1 (HMGB1) protein plays an important role in a lot of biological behaviors, including DNA damage repair, gene transcription, cell replication, and cell death, and its expression is higher in many solid tumors tissues than in their adjacent normal tissues, and it is always ...

journal_title：Journal of gastroenterology and hepatology

authors： Di X,He G,Chen H,Zhu C,Qin Q,Yan J,Zhang X,Sun X

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND AIMS:It is well known that endotoxemia, which is caused by a bacterial infection, can exacerbate acute pancreatitis, whereas pancreatitis-associated protein (PAP) has the ability to induce bacterial aggregation. Pancreatitis-associated protein is supposed to protect the tissue from infection during infla...

journal_title：Journal of gastroenterology and hepatology

authors： Wang X,Wang B,Wu J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND AIM:Multiple diagnostic and therapeutic endoscopic ultrasound (EUS) procedures have been widely performed using a standard oblique-viewing (OV) curvilinear array (CLA) echoendoscope. Recently, a new, forward-viewing (FV) CLA was developed, with the advantages of improved endoscopic viewing and manipulati...

journal_title：Journal of gastroenterology and hepatology

authors： Iwashita T,Nakai Y,Lee JG,Park DH,Muthusamy VR,Chang KJ

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND AND AIMS:The classification of gastritis by using the revised Sydney system suggests that there are two types of Helicobacter pylori-related gastritis. The aim of the present study was to examine the risk factors that might be involved in the presence of either atrophic gastritis or intestinal metaplasia of ...

journal_title：Journal of gastroenterology and hepatology

authors： Tsukui T,Kashiwagi R,Sakane M,Tabata F,Akamatsu T,Wada K,Futagami S,Miyake K,Sueoka N,Hirakawa T,Kobayashi M,Fujimori T,Sakamoto C

更新日期：2001-01-01 00:00:00

abstract：:The Swift Increase in Alcohol Metabolism occurs within 2.5 h after an acute gavage of ethanol causing an increase in hepatic respiration, an increase in alcohol metabolism, and pericentral hypoxia in the perfused liver. Alcohol treatment causes a release of endotoxin, activation of Kupffer cells to produce PGE(2), the...

journal_title：Journal of gastroenterology and hepatology

authors： Bradford BU

更新日期：2007-06-01 00:00:00

abstract：:First-degree relatives of colorectal cancer patients are at increased risk for developing colorectal neoplasms. In order to assess the potentiality of colonoscopy screening in this high-risk population, 213 asymptomatic family members (age range 30-69 years, mean 42.8 years) of those patients with colorectal cancer re...

journal_title：Journal of gastroenterology and hepatology

authors： Wu CS,Tung SY,Chen PC,Kuo YC

更新日期：1995-05-01 00:00:00

abstract：:A prospective double blind and randomized study was conducted to compare 4-aminosalicylic acid (4-ASA) and prednisolone-21-phosphate enemas in inducing remission in patients with acute distal ulcerative colitis. Patients with ulcerative colitis distal to the splenic flexure as assessed by flexible colonoscopy, barium ...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma MP,Duphare HV,Dasarathy S

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence of Helicobacter pylori-negative and nonsteroidal anti-inflammatory drug-negative peptic ulcers, commonly known as idiopathic peptic ulcers (IPUs), has been reported to be very low (0.9-2.6%) in Japan based on data from the 1990s. However, recent trends have yet to be been reported. Her...

journal_title：Journal of gastroenterology and hepatology

authors： Kanno T,Iijima K,Abe Y,Yagi M,Asonuma S,Ohyauchi M,Ito H,Koike T,Shimosegawa T

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND AIM:The vaccination against hepatitis B virus (HBV) is recommended in patients with inflammatory bowel disease (IBD). However, the response to this vaccine seems to be lower in IBD patients than in the general population. This study aims to evaluate the immunogenicity of the HBV vaccine in a cohort of pa...

journal_title：Journal of gastroenterology and hepatology

authors： Cossio-Gil Y,Martínez-Gómez X,Campins-Martí M,Rodrigo-Pendás JÁ,Borruel-Sainz N,Rodríguez-Frías F,Casellas-Jordà F

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00

abstract：:Alcohol induces Ca(2+)-dependent intracellular trypsinogen activation in the apical granular area via non-oxidative metabolites, such as fatty acid ethyl esters and fatty acids. Intracellular trypsinogen activation is a crucial initiating event in the development of acute pancreatitis, but the specific organelle in wh...

journal_title：Journal of gastroenterology and hepatology

authors： Petersen OH

更新日期：2008-03-01 00:00:00

abstract：:The prevalence and potential value of the detection of signs of portal hypertension by duplex Doppler ultrasound (DDU) of the ligamentum teres and portal vein in patients with known or suspected chronic liver disease and/or portal hypertension was studied in 136 consecutive patients undergoing clinical assessment incl...

journal_title：Journal of gastroenterology and hepatology

authors： Gibson PR,Gibson RN,Donlan JD,Ditchfield MR,Bhathal PS

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND AND AIM:Although several techniques for improved outcomes in endoscopic ultrasound (EUS)-guided tissue acquisition have been reported, the reported diagnostic yield for pancreatic masses is not satisfactory. The effects of novel technique (torque method) on twisting the scope in the clockwise or counterclock...

journal_title：Journal of gastroenterology and hepatology

authors： Park SW,Lee SS,Song TJ,Koh DH,Hyun B,Chung D,Lee J,Shin E,Hong SM,Park CH

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Saccharomyces cerevisiae may contribute to the pathophysiology of Crohn's disease. We determined serum anti-Saccharomyces cerevisiae antibody (ASCA) levels in patients with inflammatory bowel disease. METHODS AND RESULTS:Immunoglobulin G (IgG) ASCA was measured by using an ELISA in serum samples from 19 pat...

journal_title：Journal of gastroenterology and hepatology

authors： Oshitani N,Hato F,Matsumoto T,Jinno Y,Sawa Y,Hara J,Nakamura S,Seki S,Arakawa T,Kitano A,Kitagawa S,Kuroki T

更新日期：2000-12-01 00:00:00

abstract：:Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. This case of a 65-year-old Korean man with HCC and metastatic frontal bone mass that regressed after radiotherapy for frontal bone mass without any other therapeutic modalities is described. The clinical diagnosis of HCC was made because of...

journal_title：Journal of gastroenterology and hepatology

authors： Nam SW,Han JY,Kim JI,Park SH,Cho SH,Han NI,Yang JM,Kim JK,Choi SW,Lee YS,Chung KW,Sun HS

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence of ulcerative colitis (UC) is increasing steadily in Japan. In Western countries, a bimodal distribution, with UC onset peaks in youth and middle age, is observed, and smoking cessation is reported as a risk factor for UC. However, there are few reports on a bimodal distribution of ons...

journal_title：Journal of gastroenterology and hepatology

authors： Takahashi H,Matsui T,Hisabe T,Hirai F,Takatsu N,Tsurumi K,Kanemitsu T,Sato Y,Kinjyo K,Yano Y,Takaki Y,Nagahama T,Yao K,Washio M

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND AIM:CDKN2A/CDKN2B locus on 9p21 is reported to be associated with various diseases, including cancer and cardiovascular and inflammatory diseases. Significant downregulation of CDKN2B-AS1 in inflamed colon tissue of inflammatory bowel disease (IBD) cases was reported in Europeans. This study aimed to con...

journal_title：Journal of gastroenterology and hepatology

authors： Lee HS,Lee SB,Kim BM,Hong M,Jung S,Hong J,Baek J,Han B,Oh SH,Kim KM,Park SH,Yang SK,Ye BD,Song K

更新日期：2018-04-01 00:00:00

abstract：:To investigate the effect of hepatitis delta virus (HDV) superinfection on the long-term outcome of Japanese subjects with chronic hepatitis B virus (HBV) infection, we examined the presence of antibodies to hepatitis delta antigen (anti-HD) in serial serum samples collected from 1127 subjects with chronic HBV infecti...

journal_title：Journal of gastroenterology and hepatology

authors： Tamura I,Kurimura O,Koda T,Ichimura H,Katayama S,Kurimura T,Inaba Y

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) can now provide a cytopathological diagnosis of underlying pancreatic malignancy with higher success rates than endoscopic retrograde pancreatography (ERP). To determine the significance of EUS-FNA for the diagnosis of pancreatic mass without...

journal_title：Journal of gastroenterology and hepatology

authors： Wakatsuki T,Irisawa A,Bhutani MS,Hikichi T,Shibukawa G,Takagi T,Yamamoto G,Takahashi Y,Yamada Y,Watanabe K,Obara K,Suzuki T,Sato Y

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND AIM:A high yield of biopsy is mandatory to perform molecular genetic research with endoscopically obtained gastric cancer tissues. We evaluated whether probe-based confocal laser endomicroscopy (pCLE) can increase the yield of endoscopic biopsy for gastric cancer compared with white light endoscopy (WLE)...

journal_title：Journal of gastroenterology and hepatology

authors： Park CH,Kim H,Jo JH,Hahn KY,Yoon JH,Kim SY,Lee YC,Noh SH,Chung HC,Lee SK

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIM:The PyloriTek Test Kit (a 1-h rapid urease test) was developed for the rapid diagnosis of Helicobacter pylori (H. pylori) during endoscopy. Most studies were performed in Western populations. The aim of this study was to evaluate the PyloriTek test for the diagnosis of H. pylori infection in Chinese ...

journal_title：Journal of gastroenterology and hepatology

authors： Wong WM,Wong BC,Tang VS,Lai KC,Yuen ST,Leung SY,Hu WH,Lam SK

更新日期：2001-09-01 00:00:00

abstract：INTRODUCTION:Endoscopic obliteration of esophageal varices by endoscopic variceal ligation (EVL) is an effective form of secondary prophylaxis. However, there is no consensus regarding the technical aspects of EVL for secondary prophylaxis. The present study compares the technical aspects of EVL (frequency of sessions,...

journal_title：Journal of gastroenterology and hepatology

authors： Harewood GC,Baron TH,Song LM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND AIM:The aim of this study is to evaluate the epidemiology and impact of bacterial infections at admission in patients with acute decompensation (AD) of cirrhosis. METHODS:A cohort with AD of cirrhosis (European Association for the Study of the Liver criteria) admitted at a tertiary center was evaluated ...

journal_title：Journal of gastroenterology and hepatology

authors： Gupta T,Lochan D,Verma N,Rathi S,Agrawal S,Duseja A,Taneja S,Chawla YK,Dhiman RK

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND AIM:The role of hypoxia-inducible factor-1α (HIF-1α) and hypoxia-inducible factor-2α (HIF-2α) has been implicated in the clinical prognosis of hepatocellular carcinoma (HCC), but the results remain controversial. We aim to investigate the association of HIF-1α and HIF-2α overexpression with the prognosis...

journal_title：Journal of gastroenterology and hepatology

authors： Ding ZN,Dong ZR,Chen ZQ,Yang YF,Yan LJ,Li HC,Liu KX,Yao CY,Yan YC,Yang CC,Li T

更新日期：2021-01-04 00:00:00

abstract：:The reproducibility of echo-Doppler measurements of portal vein and superior mesenteric artery blood flow has not been extensively studied. In the present study, two groups of subjects were examined to test inter- and intra-observer reproducibility. Each study population consisted of 15 nonportal hypertensive and 15 p...

journal_title：Journal of gastroenterology and hepatology

authors： Iwao T,Toyonaga A,Shigemori H,Oho K,Sumino M,Sato M,Tanikawa K

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND AND AIM:The role of octamer-binding transcription factor 4 (Oct4) has been implicated in the clinical prognosis of various kinds of digestive system cancers, but the results remain controversial. The purpose of this meta-analysis is to assess the potential role of Oct4 as a prognostic marker in digestive sys...

journal_title：Journal of gastroenterology and hepatology

authors： Chen Z,Zhang L,Zhu Q,Wang X,Wu J,Wang X

更新日期：2017-03-01 00:00:00

abstract：:Forty-six patients with primary biliary cirrhosis from a single centre were studied in a randomized placebo-controlled trial to determine the effectiveness of ursodeoxycholic acid (UDCA) over a 2 year period. The two groups were well-matched at baseline. For each parameter, by calculating the difference between the me...

journal_title：Journal of gastroenterology and hepatology

authors： Turner IB,Myszor M,Mitchison HC,Bennett MK,Burt AD,James OF

更新日期：1994-03-01 00:00:00

abstract：:Despite steady progress in antiviral treatment for patients with chronic hepatitis C virus(HCV), many patients still have detectable serum HCV RNA levels by the end of interferon-based treatment and are known as virological non-responders. Re-treatment of these patients not responding to previous therapy remains chall...

journal_title：Journal of gastroenterology and hepatology

authors： Poo JL,Sánchez-Avila F,Kershenobich D,García-Samper X,Gongora J,Uribe M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatocellular carcinoma (HCC) is characteristically a hypervascular tumor and its progression is known to be closely related to angiogenesis. In this study, we investigated angiopoietin-2 (Ang-2) and vascular endothelial growth factor (VEGF) levels in the hepatic vein draining from HCC, as well as i...

journal_title：Journal of gastroenterology and hepatology

authors： Kuboki S,Shimizu H,Mitsuhashi N,Kusashio K,Kimura F,Yoshidome H,Ohtsuka M,Kato A,Yoshitomi H,Miyazaki M

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND AND AIM:Approximately 42-95% of working channels have been reported to show the presence of residual fluid despite endoscope reprocessing. The aim of this study was to design two novel protocols for cleaning residual simethicone and demonstrate its efficiency by evaluating the residual fluid and cleanliness ...

journal_title：Journal of gastroenterology and hepatology

authors： Peng CL,Liu TC,Wang HP,Chang WK

更新日期：2020-12-03 00:00:00