Spontaneous regression of a large hepatocellular carcinoma with skull metastasis.

Abstract:

:Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. This case of a 65-year-old Korean man with HCC and metastatic frontal bone mass that regressed after radiotherapy for frontal bone mass without any other therapeutic modalities is described. The clinical diagnosis of HCC was made because of the presence of a liver mass on abdominal computed tomography (CT) scan, high serum alpha-fetoprotein value and tissue diagnosis on frontal bone biopsy. The patient refused any other recommended treatments, but accepted the radiation therapy due to a painful frontal bone mass, and ingested mushroom called Phellinus linteus for one and a half years. Ten months after radiation therapy, he experienced a reduction in size of the frontal bone mass and improvement of lesions in the liver, sternum and ribs. The patient is alive and in good condition without any symptoms or tumor aggravation in August 2002. It was concluded that a rare case of spontaneous regression of HCC had occurred.

authors

Nam SW,Han JY,Kim JI,Park SH,Cho SH,Han NI,Yang JM,Kim JK,Choi SW,Lee YS,Chung KW,Sun HS

doi

10.1111/j.1440-1746.2005.03243.x

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

488-92

issue

3

eissn

0815-9319

issn

1440-1746

pii

JGH3243

journal_volume

20

pub_type

杂志文章
  • Recurrence pattern and surveillance strategy for rectal neuroendocrine tumors after endoscopic resection.

    abstract:BACKGROUND AND AIM:Endoscopic resection is highly effective treatment option for rectal neuroendocrine tumors (NETs) as they usually present as small localized tumors. However, there are no well-established surveillance strategies following endoscopic resection. We established our own protocol for the surveillance of r...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.15231

    authors: Chung HG,Goh MJ,Kim ER,Hong SN,Kim TJ,Chang DK,Kim YH

    更新日期:2020-08-31 00:00:00

  • Decreased density of interstitial cells of Cajal and neuronal cells in patients with slow-transit constipation and acquired megacolon.

    abstract:BACKGROUND:The pathophysiology of constipation is not clearly identified as yet, and the interstital cells of Cajal (ICC), known to generate the slow wave activity and to be involved in intestinal neurotransmission and the enteric nervous system (ENS), are suspected to play an important role. The aims of the present st...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2005.03809.x

    authors: Lee JI,Park H,Kamm MA,Talbot IC

    更新日期:2005-08-01 00:00:00

  • Natural history of chronic hepatitis B and C.

    abstract::Hepatitis B virus (HBV) affects more than 300 million individuals worldwide and in the United States approximately 1.25 million individuals are chronic carriers of HBV. The risk of becoming a chronic hepatitis B virus surface antigen carrier is dependent upon the mode of acquisition of infection as well as the age of ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1440-1746.1999.01903.x

    authors: Imperial JC

    更新日期:1999-05-01 00:00:00

  • The efficacy of oral Zhizhu Kuanzhong, a traditional Chinese medicine, in patients with postprandial distress syndrome.

    abstract:BACKGROUND AND AIM:The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD. METHODS:The study was designed as a multicenter, randomiz...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/jgh.14467

    authors: Xiao Y,Li Y,Shu J,Li Y,Xu J,Ren J,Liu D,Wang J,Zhou L,Li Y,Tang G,Tian D,Zhang S,Hou X,Wang H,Li Z,Lv N,Chen M

    更新日期:2019-03-01 00:00:00

  • Gene profile in the spleen under massive partial hepatectomy using complementary DNA microarray and pathway analysis.

    abstract:BACKGROUND AND AIM:In general, the spleen is one of the abdominal organs connected by the portal system, and a splenectomy improves hepatic functions in the settings of partial hepatectomy (Hx) for portal hypertensive cases or living donor liver transplantation with excessive portal vein flow. Those precise mechanisms ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12573

    authors: Arakawa Y,Shimada M,Utsunomiya T,Imura S,Morine Y,Ikemoto T,Mori H,Kanamoto M,Iwahashi S,Saito Y,Takasu C

    更新日期:2014-08-01 00:00:00

  • Secreted protein acidic and rich in cysteine promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells and acquisition of cancerstem cell phenotypes.

    abstract:BACKGROUND AND AIM:Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that plays a significant role in tumor development. SPARC has been indicated that promotes tumorigenesis, metastasis, and poor prognosis in prostate cancer and lung cancer. Therefore, we sought to investigate the mol...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.14692

    authors: Jiang X,Liu F,Wang Y,Gao J

    更新日期:2019-10-01 00:00:00

  • Detection of the preneoplastic lesions of small hepatocellular carcinoma in cirrhotic livers.

    abstract::To identify the preneoplastic lesions of hepatocellular carcinoma and the fine structure of preneoplastic hepatocytes, we studied proliferative conditions in cirrhosis of the liver. In all, 46 foci of cellular alteration (FCA), three regions of adenomatous hyperplasia (ADH), and 21 small hepatocellular carcinomas (sHC...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1993.tb01657.x

    authors: Seki S,Sakaguchi H,Kawakita N,Yanai A,Tamori A,Yabusako T,Nishiguchi S,Kuroki T,Kobayashi K,Monna T

    更新日期:1993-11-01 00:00:00

  • Factors affecting the recovery of hepatic reserve after sustained virologic response by direct-acting antiviral agents in chronic hepatitis C virus-infected patients.

    abstract:BACKGROUND AND AIM:Since the advent of direct-acting antiviral (DAA) therapy, the total eradication of hepatitis C virus has been achievable with the recovery of hepatic reserve after achievement of sustained virologic response (SVR). Hence, here, we examined the factors affecting the recovery of hepatic reserve. METH...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.15280

    authors: Nakajima T,Karino Y,Hige S,Suii H,Tatsumi R,Yamaguchi M,Arakawa T,Kuwata Y,Hasegawa T,Toyota J

    更新日期:2020-09-29 00:00:00

  • A prospective study of the clinical features, manometric findings, incidence and prevalence of achalasia in Singapore.

    abstract:BACKGROUND:This study aimed to describe the clinical features, manometric findings, prevalence and incidence of achalasia in Singapore. METHODS:A total of 615 new patients referred for oesophageal manometry between 1989 and 1996 were examined prospectively. Twenty-four men and 25 women fulfilled the manometric and cli...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.1999.01950.x

    authors: Ho KY,Tay HH,Kang JY

    更新日期:1999-08-01 00:00:00

  • Current therapeutic approaches in childhood chronic hepatitis B infection: a multicenter study.

    abstract:BACKGROUND AND AIM:The aim of the present study was to compare the therapeutic efficacy of three different regimens in childhood chronic hepatitis B (CHB) infection. METHODS:A total of 182 children with CHB infection were prospectively allocated to three random groups. Sixty-two patients in the first group received hi...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1111/j.1440-1746.2004.03209.x

    authors: Dikici B,Ozgenc F,Kalayci AG,Targan S,Ozkan T,Selimoglu A,Doganci T,Kansu A,Tosun S,Arslan N,Kasirga E,Bosnak M,Haspolat K,Buyukgebiz B,Aydogdu S,Girgin N,Yagci RV

    更新日期:2004-02-01 00:00:00

  • Meta-analysis used to identify factors associated with the effectiveness of proton pump inhibitors against non-erosive reflux disease.

    abstract:BACKGROUND:A lack of published data remains on factors associated with the treatment response to proton pump inhibitors (PPI) in patients with non-erosive reflux disease (NERD). METHODS:Studies on effectiveness of PPI in patients with NERD were identified using the MEDLINE database and manual searches of the available...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/j.1440-1746.2009.05879.x

    authors: Hiyama T,Matsuo K,Urabe Y,Fukuhara T,Tanaka S,Yoshihara M,Haruma K,Chayama K

    更新日期:2009-08-01 00:00:00

  • Prevalence of enteric pathogens among community based asymptomatic individuals.

    abstract:BACKGROUND AND AIMS:The objective of this study was to describe the prevalence of pathogenic microorganisms in asymptomatic individuals in a community study in Melbourne, Australia. METHODS:The study population was a subset of 2803 individuals participating in the Water Quality Study; a community based randomized tria...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1440-1746.2000.02089.x

    authors: Hellard ME,Sinclair MI,Hogg GG,Fairley CK

    更新日期:2000-03-01 00:00:00

  • Marked retention of indocyanine green and sulfobromophthalein with chronic persistent hepatitis.

    abstract::A hepatitis B virus (HBV) carrier with marked retention of indocyanine green (ICG) and sulfobromophthalein (BSP) was admitted to our hospital for assessment of liver function. On admission, he was asymptomatic and blood chemistry tests showed normal values for transaminases and bilirubin. Serum hepatitis B surface ant...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1993.tb01554.x

    authors: Ikejima K,Ichikawa S,Kitamura T,Watanabe S,Hirose M,Yokoi Y,Uchida S,Oide H,Suzuki H,Kitami N

    更新日期:1993-09-01 00:00:00

  • Treg subsets in inflammatory bowel disease and colorectal carcinoma: Characteristics, role, and therapeutic targets.

    abstract::T regulatory cells (Tregs) play an important role in the regulation of autoimmunity, autoinflammation, allergic diseases, infection, and the tumor environment. Different subsets are characterized that use a number of regulatory mechanisms. Tregs can influence the progression of inflammatory bowel disease and the devel...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/jgh.13342

    authors: van Herk EH,Te Velde AA

    更新日期:2016-08-01 00:00:00

  • Trend of colorectal cancer in Hong Kong: 1983-2006.

    abstract:BACKGROUND AND AIM:The incidence of colorectal cancer (CC) is increasing in many Asian countries, but decreasing in western countries. The present study examined the local incidence of CC in the past few decades. METHODS:A population based study, using data from Hong Kong (HK) Cancer Registry, was carried out to exami...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2009.06130.x

    authors: Yee YK,Gu Q,Hung I,Tan VP,Chan P,Hsu A,Pang R,Lam CS,Wong BC

    更新日期:2010-05-01 00:00:00

  • Topical application of acetic acid in cytoreduction of gastric cancer. A technical report using mouse model.

    abstract:BACKGROUND AND AIM:Application of acetic acid topically to the mucosal or serosal side of the stomach has been well used to create a chronic gastric ulcer model. The aim of the present study was to apply it as a new cytoreductive approach in a mouse model of gastric cancer. METHODS:A total of 43 genetically engineered...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2012.07070.x

    authors: Okabe S,Kodama Y,Cao H,Johannessen H,Zhao CM,Wang TC,Takahashi R,Chen D

    更新日期:2012-04-01 00:00:00

  • Fecal calprotectin and need of multiple microbiota trasplantation infusions in Clostridium difficile infection.

    abstract:BACKGROUND AND AIM:Fecal microbiota transplantation (FMT) has proven to be very effective in recurrent Clostridium difficile infection (CDI) when compared with standard antibiotic therapy. However, given the lack of validated criteria, decision regarding number and timing of infusions is currently based on the clinicia...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.15072

    authors: Gallo A,Cancelli C,Ceron E,Covino M,Capoluongo E,Pocino K,Ianiro G,Cammarota G,Gasbarrini A,Montalto M

    更新日期:2020-11-01 00:00:00

  • Daclatasvir/asunaprevir/beclabuvir, all-oral, fixed-dose combination for patients with chronic hepatitis C virus genotype 1.

    abstract:BACKGROUND AND AIM:This multinational (Taiwan, South Korea, Russia) phase 3 study evaluated the all-oral, ribavirin-free, fixed-dose combination (DCV-TRIO) of daclatasvir (NS5A inhibitor) 30 mg, asunaprevir (NS3 inhibitor) 200 mg, and beclabuvir (NS5B inhibitor) 75 mg, in patients with chronic hepatitis C virus genotyp...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.13796

    authors: Kao JH,Yu ML,Peng CY,Heo J,Chu CJ,Chang TT,Lee YJ,Hu TH,Yoon KT,Paik SW,Lim YS,Ahn SH,Isakov V,McPhee F,Hu W,Scott Swenson E,Yin PD,Treitel M

    更新日期:2017-12-01 00:00:00

  • Haemodynamic effects of enalaprilat on portal hypertension in patients with HBsAg-positive cirrhosis.

    abstract::It has been suggested that enalaprilat inhibits the renin-angiotensin-aldosterone system in plasma and tissue; it may therefore reduce portal vascular pressure owing to secondary hyperaldosteronism in patients with liver cirrhosis. In order to evaluate this concept, 20 patients with hepatitis B surface antigen (HBsAg)...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1440-1746.1995.tb01090.x

    authors: Chiang HT,Cheng JS,Lin M,Tseng WS,Chang JM,Lai KH

    更新日期:1995-05-01 00:00:00

  • Effectiveness of direct-acting agents for hepatitis C and liver stiffness changing after sustained virological response.

    abstract:BACKGROUND AND AIM:Few studies have evaluated sustained virological response (SVR) rates by direct-acting agents (DAAs) and liver stiffness measurement (LSM) changing post-SVR in limited-resource settings. We aimed to describe the effectiveness of DAAs for hepatitis C virus treatment and to assess the changing of LSM p...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/jgh.14707

    authors: Fernandes FF,Piedade J,Guimaraes L,Nunes EP,Chaves U,Goldenzon RV,Cardoso SW,Duarte J,Grinsztejn B,Veloso VG,Pereira G,Perazzo H

    更新日期:2019-12-01 00:00:00

  • Impact of the branched-chain amino acid to tyrosine ratio and branched-chain amino acid granule therapy in patients with hepatocellular carcinoma: A propensity score analysis.

    abstract:BACKGROUND AND AIM:It has been reported that the branched-chain amino acid (BCAA) to tyrosine ratio (BTR) is a useful indicator of liver function and BCAA therapy is associated with a decreased incidence of hepatocellular carcinoma (HCC). However, there has not been sufficient research on the relationship between BTR a...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12954

    authors: Tada T,Kumada T,Toyoda H,Kiriyama S,Tanikawa M,Hisanaga Y,Kanamori A,Kitabatake S,Yama T

    更新日期:2015-09-01 00:00:00

  • Low prevalence of Helicobacter pylori but high prevalence of cytomegalovirus-associated peptic ulcer disease in AIDS patients: Comparative study of symptomatic subjects evaluated by endoscopy and CD4 counts.

    abstract:BACKGROUND AND AIMS:The role of Helicobacter pylori infection in gastroduodenal lesions might be different between the general population and AIDS patients. The aim of the present study was to compare the prevalence of H. pylori and cytomegalovirus (CMV) infection in AIDS patients and HIV-negative controls. The impact ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2003.03278.x

    authors: Chiu HM,Wu MS,Hung CC,Shun CT,Lin JT

    更新日期:2004-04-01 00:00:00

  • Fibroscan can avoid liver biopsy in Indian patients with chronic hepatitis B.

    abstract:BACKGROUND AND AIM:Liver fibrosis is an established determinant of prognosis and therapy in chronic hepatitis B (CHB). The role of fibroscan in assessing fibrosis in CHB remains unclear. Present study was designed to correlate fibroscan with liver biopsy and determine whether fibroscan can avoid liver biopsy in patient...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12318

    authors: Goyal R,Mallick SR,Mahanta M,Kedia S,Shalimar,Dhingra R,Sharma H,Das P,Datta Gupta S,Panda S,Acharya SK

    更新日期:2013-11-01 00:00:00

  • Evaluation of an antigen assay for diagnosing acute and chronic hepatitis E genotype 4 infection.

    abstract:BACKGROUND AND AIM:Results obtained from different hepatitis E virus (HEV) tests are usually inconsistent. The detection of serum HEV antigen (Ag) has been suggested to be more sensitive for the diagnosis of genotypes 1 and 3 HEV. METHODS:We compared the diagnostic accuracies of serum HEV Ag and HEV RNA by using 202 s...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.14405

    authors: Zhang H,Rao H,Wang Y,Wang J,Kong X,Ji Y,Zhu L,Liu Y,Fang J,Yang M,Luo B,Wang Z,Shi Y,Wang Y,Wang H,Zhao J,Wei L

    更新日期:2019-02-01 00:00:00

  • Repeated water avoidance stress induces visceral hypersensitivity: Role of interleukin-1, interleukin-6, and peripheral corticotropin-releasing factor.

    abstract:BACKGROUND AND AIM:Repeated water avoidance stress (WAS) induces visceral hypersensitivity. Additionally, it is also known to activate corticotropin-releasing factor (CRF), mast cells, and pro-inflammatory cytokines systems, but their precise roles on visceral sensation have not been determined definitely. The aim of t...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.13787

    authors: Nozu T,Miyagishi S,Nozu R,Takakusaki K,Okumura T

    更新日期:2017-12-01 00:00:00

  • Oesophageal motility and gastro-oesophageal reflux: effect of variceal eradication by endoscopic sclerotherapy.

    abstract::Endoscopic injection sclerotherapy (EIS) is known to produce oesophageal structural and motility changes; however, alterations in frequency and severity of gastro-oesophageal reflux (GER) following EIS have not been investigated in detail. We studied 22 patients with cirrhosis and oesophageal varices before EIS and 26...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1998.tb00566.x

    authors: Ghoshal UC,Saraswat VA,Aggarwal R,Misra A,Dhiman RK,Naik SR

    更新日期:1998-10-01 00:00:00

  • Post-partum acute exacerbation of chronic hepatitis in a hepatitis C-carrier mother.

    abstract::Hepatitis C virus infection is a global health problem; however, the interaction between pregnancy and chronic hepatitis C remains controversial. A Taiwanese woman with chronic hepatitis C had an uncomplicated pregnancy and gave birth to a female baby through spontaneous vaginal delivery. The serum levels of alanine a...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2001.02502.x

    authors: Chen JD,Chung JL,Kao JH,Chen DS

    更新日期:2001-06-01 00:00:00

  • Systematic review with meta-analysis: accuracy of interferon-gamma releasing assay and anti-Saccharomyces cerevisiae antibody in differentiating intestinal tuberculosis from Crohn's disease in Asians.

    abstract:BACKGROUND AND AIMS:Distinguishing Crohn's disease (CD) from intestinal tuberculosis (ITB) is a clinical challenge. This meta-analysis assessed the clinical usefulness of Interferon-gamma releasing assay (IGRA) and anti-Saccharomyces cerevisiae antibody (ASCA) in the diagnosis of ITB and CD, respectively. METHODS:Syst...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/jgh.12645

    authors: Ng SC,Hirai HW,Tsoi KK,Wong SH,Chan FK,Sung JJ,Wu JC

    更新日期:2014-09-01 00:00:00

  • Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease.

    abstract:BACKGROUND AND AIMS:Dysbiosis is thought to be relevant to the etiology and pathogenesis of Crohn's disease (CD). In this study, we investigated the abundance of Faecalibacterium prausnitzii, as well as Bilophila wadsworthia, in the gut microbiota of Japanese CD patients. METHODS:Forty-seven CD patients and 20 healthy...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12073

    authors: Fujimoto T,Imaeda H,Takahashi K,Kasumi E,Bamba S,Fujiyama Y,Andoh A

    更新日期:2013-04-01 00:00:00

  • Is Helicobacter pylori the primary cause of duodenal ulceration?

    abstract::Helicobacter pylori infection may not be the primary cause of duodenal ulceration in cases not associated with non-steroidal anti-inflammatory drugs, but may be a secondary complication. In developing countries with a uniformly high prevalence of H. pylori infection there are marked regional differences in the prevale...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1046/j.1440-1746.1999.02005.x

    authors: Tovey FI,Hobsley M

    更新日期:1999-11-01 00:00:00