Cyclo-oxygenase-2 inhibitors suppress epithelial cell kinetics and delay gastric wound healing in rats.

abstract：BACKGROUND:Thrombocytopenia is a common manifestation of liver cirrhosis (LC), but its underlying mechanism is not fully understood. The purpose of the present paper was to evaluate the platelet kinetics in LC patients by examining several non-invasive convenient markers. METHODS:Fifty-seven LC patients, 32 patients w...

journal_title：Journal of gastroenterology and hepatology

authors： Kajihara M,Okazaki Y,Kato S,Ishii H,Kawakami Y,Ikeda Y,Kuwana M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND AIM:KRAS mutation analysis may provide ancillary diagnostic yield in an endoscopic ultrasound (EUS)-guided histopathological evaluation. We evaluated the clinical impact of KRAS mutation analysis with cytological and histological evaluations in EUS-guided tissue sampling, using a core biopsy needle for s...

journal_title：Journal of gastroenterology and hepatology

authors： Choi HJ,Moon JH,Kim HK,Lee YN,Lee TH,Cha SW,Cho YD,Park SH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND AIM:Although several techniques for improved outcomes in endoscopic ultrasound (EUS)-guided tissue acquisition have been reported, the reported diagnostic yield for pancreatic masses is not satisfactory. The effects of novel technique (torque method) on twisting the scope in the clockwise or counterclock...

journal_title：Journal of gastroenterology and hepatology

authors： Park SW,Lee SS,Song TJ,Koh DH,Hyun B,Chung D,Lee J,Shin E,Hong SM,Park CH

更新日期：2020-03-01 00:00:00

abstract：:The effects of ethanol and its metabolites on collagen synthesis in cultured rat Ito cells and hepatocytes were studied. In cultured Ito cells, collagen synthetic ability reached peak values after incubation for 24 h and after 8 h in cultured hepatocytes. The distribution patterns of 14C-activity in each collagen frac...

journal_title：Journal of gastroenterology and hepatology

authors： Tsutsumi M,Takada A,Takase S,Shimanaka K,Enyama K

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND AND AIM:Multidrug resistance associated gene product 2 (Mdr2) is believed to have a significant role in biliary cholesterol and phospholipid secretions. Both pravastatin and bezafibrate resulted in Mdr2 induction, but increased cholesterol secretion was observed only in pravastatin treatment. To explore the ...

journal_title：Journal of gastroenterology and hepatology

authors： Kamisako T,Ogawa H

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND AND AIM:A subcirrhotic range of liver stiffness (sc-LS), assessed by transient elastography, is associated with better outcomes in patients with chronic hepatitis B (CHB). We investigated whether the achievement of sc-LS by antiviral therapy (AVT) reduced the risk of developing hepatocellular carcinoma (HCC)...

journal_title：Journal of gastroenterology and hepatology

authors： Kim BS,Seo YS,Kim YS,Lee CH,Lee HA,Um SH,Yoo JJ,Kim SG,Suh SJ,Jung YK,Ahn SH,Han KH,Yim HJ,Kim SU,Korean Transient Elastography Study Group.

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The association between body mass index (BMI) and mortality from gastrointestinal (GI) cancer remains unclear, especially in Asian populations. METHODS:A total of 510 148 Korean adults who participated in routine health examinations during the period 2002-2003 were followed up until 2013. RESULTS:During a ...

journal_title：Journal of gastroenterology and hepatology

authors： Jeong SH,Kim P,Yi SW,Kim YJ,Baeg MK,Yi JJ

更新日期：2018-02-06 00:00:00

abstract：BACKGROUND AND AIM:Repeated water avoidance stress (WAS) induces visceral hypersensitivity. Additionally, it is also known to activate corticotropin-releasing factor (CRF), mast cells, and pro-inflammatory cytokines systems, but their precise roles on visceral sensation have not been determined definitely. The aim of t...

journal_title：Journal of gastroenterology and hepatology

authors： Nozu T,Miyagishi S,Nozu R,Takakusaki K,Okumura T

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Minimal hepatic encephalopathy (MHE) is the mildest form of hepatic encephalopathy (HE) and is characterized by deficits in neurocognitive performance without any clinical symptoms of HE. In the current study, we aim to evaluate and compare the neurocognitive, biochemical, and brain magnetic resonan...

journal_title：Journal of gastroenterology and hepatology

authors： Yadav SK,Goel A,Saraswat VA,Thomas MA,Wang E,Marincola FM,Haris M,Gupta RK

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND AIM:To appraise the current reporting methodological quality of meta-analyses in five leading gastroenterology and hepatology journals, and to identify the variables associated with the reporting quality. METHODS:We systematically searched the literature of meta-analyses in Gastroenterology, Gut, Hepato...

journal_title：Journal of gastroenterology and hepatology

authors： Liu P,Qiu Y,Qian Y,Chen X,Wang Y,Cui J,Zhai X

更新日期：2017-01-01 00:00:00

abstract：:In order to achieve possible greater therapeutic efficacy, ranitidine 300 mg bid (R2) may be given rather than 300 mg qhs (R1), or nizatidine 300 mg bid (N2) may be given rather than 300 mg qhs (N1). A randomized placebo-controlled crossover study was performed in six healthy volunteers (four males, two females) who r...

journal_title：Journal of gastroenterology and hepatology

authors： Thompson A,Kirdeikis P,Jamali F,Tavernini M,Zuk L,Marriage B,Simpson I,Mahachai V

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND AND AIM:The present study aimed to evaluate the non-inferiority of low-volume oral sulfate solution (OSS) to 4-L polyethylene glycol (PEG) solutions administered in a split-dose regimen as bowel preparation for colonoscopy. The safety and tolerability were also compared between the two regimens. METHODS:In ...

journal_title：Journal of gastroenterology and hepatology

authors： Yang HJ,Park SK,Kim JH,Im JP,Yeom DH,Seo GS,Park DI

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Sodium chloride (NaCl) is a strong promoter of gastric cancer. We hypothesized that inducible nitric oxide synthase (iNOS) induced by NaCl may be involved in its promoting effects. We investigated iNOS expression by hypertonic NaCl solutions and its pathophysiological roles in the gastric mucosa of rats and ...

journal_title：Journal of gastroenterology and hepatology

authors： Tatemichi M,Ogura T,Sakurazawa N,Nagata H,Sugita M,Esumi H

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND AND AIM:Nonattendance of outpatient colonoscopy leads to inefficient use of health-care resources. We aimed to study the effectiveness of using Short Message Service (SMS) reminder prior in patients scheduled for outpatient colonoscopy on their nonattendance rate. METHODS:Patients who scheduled for an outpa...

journal_title：Journal of gastroenterology and hepatology

authors： Lam TYT,Hui AJ,Sia F,Wong MY,Lee CCP,Chung KW,Lau JYW,Wu PI,Sung JJY

更新日期：2020-08-16 00:00:00

abstract：BACKGROUND AND AIM:The mechanisms of ribavirin as an immune modulator have not been fully revealed, contrary to its clinical benefit in chronic hepatitis C. Recently, host immune defense, especially cytotoxic T lymphocytes and T helper cells, have been considered to be closely related to the pathophysiology of chronic ...

journal_title：Journal of gastroenterology and hepatology

authors： Shiina M,Kobayashi K,Satoh H,Niitsuma H,Ueno Y,Shimosegawa T

更新日期：2004-05-01 00:00:00

abstract：:The Asia-Pacific Consensus Conference was convened to review and synthesize the most current information on Helicobacter pylori management so as to update the previously published regional guidelines. The group recognized that in addition to long-established indications, such as peptic ulcer disease, early mucosa-asso...

journal_title：Journal of gastroenterology and hepatology

authors： Fock KM,Katelaris P,Sugano K,Ang TL,Hunt R,Talley NJ,Lam SK,Xiao SD,Tan HJ,Wu CY,Jung HC,Hoang BH,Kachintorn U,Goh KL,Chiba T,Rani AA,Second Asia-Pacific Conference.

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:The efficacy and safety of peginterferon alpha-2a (40 KD) (peg-IFNalpha-2a) plus ribavirin has not been reported for Japanese patients with chronic hepatitis C. The aim of this study was to evaluate this combination in treatment-naïve patients and in non-responders or relapsers to interferon monotherapy. ME...

journal_title：Journal of gastroenterology and hepatology

authors： Kuboki M,Iino S,Okuno T,Omata M,Kiyosawa K,Kumada H,Hayashi N,Sakai T

更新日期：2007-05-01 00:00:00

abstract：:The prevalence and potential value of the detection of signs of portal hypertension by duplex Doppler ultrasound (DDU) of the ligamentum teres and portal vein in patients with known or suspected chronic liver disease and/or portal hypertension was studied in 136 consecutive patients undergoing clinical assessment incl...

journal_title：Journal of gastroenterology and hepatology

authors： Gibson PR,Gibson RN,Donlan JD,Ditchfield MR,Bhathal PS

更新日期：1991-01-01 00:00:00

abstract：AIM:To evaluate granulocytapheresis (GCAP) in active ulcerative colitis (UC), with particular attention to the long-term effects of such treatment. METHODS:We included 80 patients with UC. Activity of the disease was evaluated by clinical activity index and endoscopic index. Patients were randomly divided in two group...

journal_title：Journal of gastroenterology and hepatology

authors： Bresci G,Parisi G,Mazzoni A,Scatena F,Capria A

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Cystinosis is a metabolic disease characterized by accumulation of cystine in different organs and tissues, leading to potentially life-threatening organ dysfunction. Infantile cystinosis typically leads to end-stage renal disease, necessitating renal replacement therapy. Liver disease in cystinosis is rare ...

journal_title：Journal of gastroenterology and hepatology

authors： Cornelis T,Claes K,Gillard P,Nijs E,Roskams T,Lombaerts R,Nevens F,Cassiman D

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND AIMS:We have shown previously that concentrations of stool decay-accelerating factor (DAF; CD55), a complement regulatory protein, in patients with ulcerative colitis (UC) are increased in relation to the severity of the colonic mucosal inflammation. In the present study, we evaluated the usefulness of s...

journal_title：Journal of gastroenterology and hepatology

authors： Kohno H,Mizuno M,Nasu J,Makidono C,Hiraoka S,Inaba T,Yamamoto K,Okada H,Fujita T,Shiratori Y

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND AIM:Host genetic factors have been reported as influencing the progress to fulminant hepatitis (FH). Our previous data showed the serum level of tumor necrosis factor (TNF)-alpha influenced by gene polymorphisms to be markedly increased. It was investigated whether polymorphisms in the IL-10 gene, in add...

journal_title：Journal of gastroenterology and hepatology

authors： Takakura M,Tokushige K,Matsushita N,Hashimoto E,Shiratori K

更新日期：2007-08-01 00:00:00

abstract：:This study examined Na+/H+ ion exchange of caecal and colonic mucus. Two distinct Na+/H+ ion exchange populations of caecal mucus were identified, one group being a cation exchanger and the other an anion exchanger, suggesting that caecal mucus has ampholyte properties responsive to changing physical and chemical prop...

journal_title：Journal of gastroenterology and hepatology

authors： Duncan CE,Tasman-Jones C

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND AIM:Same-day bidirectional endoscopy, including esophagogastroduodenoscopy (EGD) and colonoscopy, is frequently performed to screen for cancer and gastrointestinal bleeding. However, the optimal sequence for the procedures is unclear thus far. The aim of this study was to evaluate the optimal sequence fo...

journal_title：Journal of gastroenterology and hepatology

authors： Hsieh YH,Lin HJ,Tseng KC

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND AND AIM:Although endoscopic ultrasound-guided fine-needle biopsy is widely applied, there is no clear consensus on the optimal biopsy technique. We described a modified wet suction technique (MWEST) with the aim to compare the efficacy and safety between MWEST and the dry suction technique (DST). METHODS:In...

journal_title：Journal of gastroenterology and hepatology

authors： Tong T,Tian L,Deng M,Liu Y,Yang Y,Yin H,Long X,Pan S,Yang Z,Luo W,Nie K,Meng X,Xiao M,Wu X,Zhang C,Wang X

更新日期：2020-12-08 00:00:00

abstract：:At Royal Perth Hospital, Western Australia in April 1982, spiral bacteria were first cultured from a gastric biopsy specimen. Several important taxonomic features were identified which indicated that these bacteria represented a new genus. In October 1989 the new genus name Helicobacter was published. Helicobacter pyl...

journal_title：Journal of gastroenterology and hepatology

authors： Goodwin CS

更新日期：1994-01-01 00:00:00

abstract：:Typhoid fever is often associated with abnormal liver biochemical tests, but severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. There have been more than 150 cases of salmonella hepatitis reported from both developed and developing countries. The documented incidence varies w...

journal_title：Journal of gastroenterology and hepatology

authors： Pramoolsinsap C,Viranuvatti V

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:In order to evaluate some possible risk factors for the spread of hepatitis C infection a case-control study was undertaken. METHODS:The study population consisted of first time blood donors referred to the Iranian Blood Transfusion Organization. Enzyme-linked immunosorbent assay and recombinant immunoblot ...

journal_title：Journal of gastroenterology and hepatology

authors： Alavian SM,Gholami B,Masarrat S

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Toll-like receptors (TLRs) are involved in innate immunity. Certain viruses interact with TLRs and mediate antiviral effects as well as immune responses. The aim of this study was to investigate the effect of TLRs on pathogenesis in hepatitis C virus (HCV)-infected patients. METHODS:Peripheral blood mononuc...

journal_title：Journal of gastroenterology and hepatology

authors： Sato K,Ishikawa T,Okumura A,Yamauchi T,Sato S,Ayada M,Matsumoto E,Hotta N,Oohashi T,Fukuzawa Y,Kakumu S

更新日期：2007-10-01 00:00:00

abstract：:The mechanism of phagocytosis by Kupffer cells has been shown to be related to the Ca(2+)-calmodulin and the actomyosin systems. However the role of the transmembrane signal transmitter, G-protein, is still unknown. In this study, a quantitative evaluation of phagocytosis by Kupffer cells of rats in culture and the ef...

journal_title：Journal of gastroenterology and hepatology

authors： Hirose M,Watanabe S,Ueno T,Kitami N,Sato N

更新日期：1993-07-01 00:00:00