Prevalence and risk factors for non-alcoholic fatty liver disease among adults in an urban Sri Lankan population.

abstract：:Hepatitis B virus (HBV) affects more than 300 million individuals worldwide and in the United States approximately 1.25 million individuals are chronic carriers of HBV. The risk of becoming a chronic hepatitis B virus surface antigen carrier is dependent upon the mode of acquisition of infection as well as the age of ...

journal_title：Journal of gastroenterology and hepatology

authors： Imperial JC

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND AND AIM:Ecabet sodium is reported to have a bactericidal effect on Helicobacter pylori and inhibit urease activity in vitro. METHODS:Seven male volunteers (mean age, 51.3 years; range, 45-55 years) with H. pylori infection were medicated with 1 g ecabet sodium t.i.d. for 4 weeks. The urea breath test (UBT) ...

journal_title：Journal of gastroenterology and hepatology

authors： Okuda M,Yamamoto N,Fukuda N,Maekawa K,Kusaka T,Hashimoto M,Kotake J,Koizuka H,Fukuda Y

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND AIM:Early life exposure to the famine may affect the susceptibility to the metabolic disorders. The objective of this study was to examine the associations of early life exposure to the Chinese Famine (1959-1961) with the risk of fatty liver disease, obesity, hypertension, and hyperglycemia in adulthood....

journal_title：Journal of gastroenterology and hepatology

authors： Chen JP,Peng B,Tang L,Sun R,Hu S,Wen XY,Que P,Wang YH

更新日期：2016-01-01 00:00:00

abstract：:At Royal Perth Hospital, Western Australia in April 1982, spiral bacteria were first cultured from a gastric biopsy specimen. Several important taxonomic features were identified which indicated that these bacteria represented a new genus. In October 1989 the new genus name Helicobacter was published. Helicobacter pyl...

journal_title：Journal of gastroenterology and hepatology

authors： Goodwin CS

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Data on anorectal physiology in patients with disordered thyroid metabolism are lacking. This prospective study was performed to evaluate anorectal physiology in patients with either hyperthyroidism and diarrhoea, or hypothyroidism and constipation in order to assess slow transit in hypothyroid patients. ME...

journal_title：Journal of gastroenterology and hepatology

authors： Deen KI,Seneviratne SL,de Silva HJ

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND AIM:The technical performance of colonoscopy performed in deeply sedated patients differs from that performed without sedation or under minimal to moderate sedation. The aim of this study is to evaluate the factors affecting cecal intubation during colonoscopy performed under deep sedation. METHODS:A to...

journal_title：Journal of gastroenterology and hepatology

authors： Hsu CM,Lin WP,Su MY,Chiu CT,Ho YP,Chen PC

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND AIM:There are few studies investigating the treatment of hepatitis C virus (HCV) infection in current and former drug users. With this in mind, we sought to evaluate the antiviral efficacy of interferon alpha-2b (IFN alpha-2b) or pegylated-interferon alpha-2b (PEG-IFN alpha-2b) and ribavirin (RBV) in inj...

journal_title：Journal of gastroenterology and hepatology

authors： Grebely J,Raffa JD,Meagher C,Duncan F,Genoway KA,Khara M,McLean M,Mead A,Viljoen M,DeVlaming S,Fraser C,Conway B

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND AND AIM:KRAS mutation analysis may provide ancillary diagnostic yield in an endoscopic ultrasound (EUS)-guided histopathological evaluation. We evaluated the clinical impact of KRAS mutation analysis with cytological and histological evaluations in EUS-guided tissue sampling, using a core biopsy needle for s...

journal_title：Journal of gastroenterology and hepatology

authors： Choi HJ,Moon JH,Kim HK,Lee YN,Lee TH,Cha SW,Cho YD,Park SH

更新日期：2017-01-01 00:00:00

abstract：:The incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade to become a global disease. The increasing number of studies on the incidence and course of IBD in East has enabled us to explore East versus West differences in the epidemiology of IBD which could enhance our understanding of th...

journal_title：Journal of gastroenterology and hepatology

authors： Mak WY,Zhao M,Ng SC,Burisch J

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND AND AIM:The significance of serum levels of transforming growth factor (TGF)-beta1 in the development of gastric cancer is unclear. The purpose of this study is to determine whether serum TGF-beta1 correlated with the clinicopathological findings of patients with gastric cancer. METHODS:Transforming growth ...

journal_title：Journal of gastroenterology and hepatology

authors： Lin Y,Kikuchi S,Obata Y,Yagyu K,Tokyo Research Group on Prevention of Gastric Cancer.

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND AND AIM:Hyponatremia is associated with development of hepatic encephalopathy (HE), but the nature of the relationship between serum sodium and HE incidence is unknown. We examined the association between serum sodium, changes in serum sodium, and HE incidence using data from three randomized trials of satav...

journal_title：Journal of gastroenterology and hepatology

authors： Bossen L,Ginès P,Vilstrup H,Watson H,Jepsen P

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIM:In hilar cholangiocarcinoma, an accurate assessment of preoperative resectability is important to optimize surgical resection. We investigated the accuracy of the combination of intraductal ultrasonography (IDUS) and percutaneous transhepatic cholangioscopy (PTCS) for evaluating longitudinal extent i...

journal_title：Journal of gastroenterology and hepatology

authors： Kim HM,Park JY,Kim KS,Park MS,Kim MJ,Park YN,Bang S,Song SY,Chung JB,Park SW

更新日期：2010-02-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the major cancers in the world. There is a striking variation in HCC incidence rates between various countries, with a highest-to-lowest ratio of 112.5 for males and 54.7 for females. The high-risk populations are clustered in sub-Saharan Africa and eastern Asia. The male-to-fe...

journal_title：Journal of gastroenterology and hepatology

authors： Chen CJ,Yu MW,Liaw YF

更新日期：1997-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a major cause of hepatocellular carcinoma (HCC) and chronic liver disease worldwide. Recent developments and advances in HCV replication systems in vitro and in vivo, transgenic animal models, and gene expression profiling approaches have provided novel insights into the mechanisms...

journal_title：Journal of gastroenterology and hepatology

authors： Yamashita T,Honda M,Kaneko S

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND AIM:Recently, microRNAs (miRNA) have been linked to the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH). First transcribed as pri-miRNA, these molecules are further processed by a complex of endonuclear and cytosolic RNA binding molecu...

journal_title：Journal of gastroenterology and hepatology

authors： Sharma H,Estep M,Birerdinc A,Afendy A,Moazzez A,Elariny H,Goodman Z,Chandhoke V,Baranova A,Younossi ZM

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND AIM:We previously discovered that tumor suppressor candidate 3 (TUSC3) was overexpressed and predicted worse prognosis in colon cancer patients. However, the mechanisms of upregulation of TUSC3 in colon cancer remained unclear. METHODS:MiR-873-5p was predicted and identified as the regulator of TUSC3 vi...

journal_title：Journal of gastroenterology and hepatology

authors： Zhu Y,Zhang X,Qi M,Zhang Y,Ding F

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The pathogenesis of non-alcoholic steatohepatitis (NASH) is unclear. Recent studies suggested that oxidative stress plays an important role in the mechanism of NASH. Excessive accumulation of iron in the liver causes oxidative stress. The aim of the present study was to evaluate the grade of hepatic iron acc...

journal_title：Journal of gastroenterology and hepatology

authors： Yamamoto M,Iwasa M,Iwata K,Kaito M,Sugimoto R,Urawa N,Mifuji R,Konishi M,Kobayashi Y,Adachi Y

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Probucol is a lipid-lowering agent with anti-oxidant effects. Oxidative stress and inflammation are important in the pathophysiology of insulin resistance. We aimed to evaluate the effects of probucol on liver histological changes, serum and hepatic levels of adipokines in rats with high fat-induced...

journal_title：Journal of gastroenterology and hepatology

authors： Zhang X,Li Z,Liu D,Xu X,Shen W,Mei Z

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Direct-acting antivirals (DAAs) rapidly clear hepatitis C virus (HCV), but the lipid dynamics after DAA treatment remain unknown. Low-density lipoprotein (LDL) cholesterolemia is the predicting factor for the onset and death of atherosclerotic cardiovascular diseases. Thus, in this study, we examined the fre...

journal_title：Journal of gastroenterology and hepatology

authors： Morihara D,Ko YL,Shibata K,Yamauchi R,Fukuda H,Tsuchiya N,Fukunaga A,Kunimoto H,Iwashita H,Takata K,Tanaka T,Sakurai K,Inomata S,Yokoyama K,Nishizawa S,Takeyama Y,Irie M,Shakado S,Sohda T,Sakisaka S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The expressions of CD95 (Fas/APO-1) and Bcl-2 are determinants of apoptosis in normal lymphocytes, and abnormalities in their expressions might contribute to the induction of autoimmunity. In this study, we examined the expressions of CD95 and Bcl-2 on freshly isolated T and B cells from patients with autoim...

journal_title：Journal of gastroenterology and hepatology

authors： Ogawa S,Sakaguchi K,Takaki A,Shiraga K,Sawayama T,Mouri H,Miyashita M,Koide N,Tsuji T

更新日期：2000-01-01 00:00:00

abstract：:Worldwide the need for effective therapy for chronic hepatitis B is similar to that for chronic hepatitis C. Current licensed treatment for chronic hepatitis B (interferon (IFN)-alpha, lamivudine) does not significantly alter the natural history of the disease because the frequency of sustained response is too low; ho...

journal_title：Journal of gastroenterology and hepatology

authors： Schalm SW,De Man RA,Janssen HL

更新日期：2002-12-01 00:00:00

abstract：:Eradication of Helicobacter pylori infection is known to reduce the incidence of duodenal ulcer recurrence. The most commonly used regimen for H. pylori infection is triple antimicrobial therapy for 1-2 weeks. This treatment is associated with frequent side effects and hence unsatisfactory compliance. As in vitro data...

journal_title：Journal of gastroenterology and hepatology

authors： Sung JJ,Chung SC,Hosking SW,Chan RC,Ling TK,Yung MY,Cheng AF,Li AK

更新日期：1995-01-01 00:00:00

abstract：:Mucus and bicarbonate secretions have been widely implicated as an important pre-epithelial protective barrier against autodigestion of the gastric mucosa by acid and pepsin. Evidence from several independent studies shows there is a continuous layer of resilient viscoelastic mucus gel adherent to the surface of the g...

journal_title：Journal of gastroenterology and hepatology

authors： Copeman M,Matuz J,Leonard AJ,Pearson JP,Dettmar PW,Allen A

更新日期：1994-01-01 00:00:00

abstract：:Endoscopic injection sclerotherapy (EIS) is known to produce oesophageal structural and motility changes; however, alterations in frequency and severity of gastro-oesophageal reflux (GER) following EIS have not been investigated in detail. We studied 22 patients with cirrhosis and oesophageal varices before EIS and 26...

journal_title：Journal of gastroenterology and hepatology

authors： Ghoshal UC,Saraswat VA,Aggarwal R,Misra A,Dhiman RK,Naik SR

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Currently, hepatitis B immunoglobulins (HBIg) and/or lamivudine have become the main options for prevention of hepatitis B recurrence after liver transplantation. AIM:To assess the benefits of HBIg and/or lamivudine for prevention of hepatitis B recurrence after liver transplantation. METHODS:We conducted ...

journal_title：Journal of gastroenterology and hepatology

authors： Chen J,Yi L,Jia JD,Ma H,You H

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND AIM:A subcirrhotic range of liver stiffness (sc-LS), assessed by transient elastography, is associated with better outcomes in patients with chronic hepatitis B (CHB). We investigated whether the achievement of sc-LS by antiviral therapy (AVT) reduced the risk of developing hepatocellular carcinoma (HCC)...

journal_title：Journal of gastroenterology and hepatology

authors： Kim BS,Seo YS,Kim YS,Lee CH,Lee HA,Um SH,Yoo JJ,Kim SG,Suh SJ,Jung YK,Ahn SH,Han KH,Yim HJ,Kim SU,Korean Transient Elastography Study Group.

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The reasons for the viral persistence of hepatitis B virus infection (HBV) are unknown, but are probably related to host immune factors. Cytokines play a significant role in immune defense. The present study was undertaken to investigate the association between HBV infection and polymorphisms of tumor necros...

journal_title：Journal of gastroenterology and hepatology

authors： Cheong JY,Cho SW,Hwang IL,Yoon SK,Lee JH,Park CS,Lee JE,Hahm KB,Kim JH

更新日期：2006-07-01 00:00:00

abstract：:There is an increasing burden in digestive cancer in the coming years. With the advancement of endoscopic therapy, new molecular target therapy and minimally invasive ablation therapy, the treatment of digestive cancer will become more complicated. In Asia where gastric cancer and hepatocellular carcinoma are still pr...

journal_title：Journal of gastroenterology and hepatology

authors： Sung J

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND AIM:A recent study in Indian subjects suggested common variants in apolipoprotein C3 (APOC3) (T-455C at rs2854116 and C-482T at rs2854117) to contribute to non-alcoholic fatty liver disease (NAFLD), plasma apoC3 and triglyceride concentrations. Our aim was to determine the contribution of genetic variati...

journal_title：Journal of gastroenterology and hepatology

authors： Hyysalo J,Stojkovic I,Kotronen A,Hakkarainen A,Sevastianova K,Makkonen J,Lundbom N,Rissanen A,Krauss RM,Melander O,Orho-Melander M,Yki-Järvinen H

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND AND AIM:This study sought to investigate the effects of hypothermia induced by adenosine 5'-monophosphate (5'-AMP) on L-arginine (L-Arg)-induced acute pancreatitis in rats. METHODS:The rats were divided into four groups: the control group, the acute pancreatitis group, the 5'-AMP pretreatment group, and the...

journal_title：Journal of gastroenterology and hepatology

authors： Wang Y,Guo W,Li Y,Pan X,Lv W,Cui L,Li C,Wang Y,Yan S,Zhang J,Liu B

更新日期：2014-04-01 00:00:00