Abstract:
BACKGROUND AND AIM:Ecabet sodium is reported to have a bactericidal effect on Helicobacter pylori and inhibit urease activity in vitro. METHODS:Seven male volunteers (mean age, 51.3 years; range, 45-55 years) with H. pylori infection were medicated with 1 g ecabet sodium t.i.d. for 4 weeks. The urea breath test (UBT) was performed 10 times per person: before medication, seven times in 2 weeks, and once in the third and fourth weeks. Stool antigen tests (HpSA PLUS and Testmate pylori antigen) were performed five times per person: before medication and weekly during medication. RESULTS:The premedication UBT value ranged from 4.9 ‰ to 77.4 ‰ and from 2.9 ‰ to 44 ‰ at the end of the treatment period. Not one of the subjects had a negative UBT result during medication. The optical densities of the HpSA and Testmate pylori antigen tests ranged from 0.4 to > 3.0 premedication and from 0.0 to > 3.0 at the end of treatment. HpSA and Testmate pylori antigen were negative in two cases. CONCLUSIONS:In this study, ecabet sodium did not effect the results of UBT in volunteers with H. pylori infection. Ecabet sodium may influence stool antigens because in two of seven cases the H. pylori stool antigen tests returned negative results.
journal_name
J Gastroenterol Hepatoljournal_title
Journal of gastroenterology and hepatologyauthors
Okuda M,Yamamoto N,Fukuda N,Maekawa K,Kusaka T,Hashimoto M,Kotake J,Koizuka H,Fukuda Ydoi
10.1111/j.1440-1746.2012.07080.xsubject
Has Abstractpub_date
2012-04-01 00:00:00pages
100-2eissn
0815-9319issn
1440-1746journal_volume
27 Suppl 3pub_type
杂志文章abstract::In order to detect both pancreatic excretion of dimethadione (DMO), a weak organic acid, and the effect of pancreatic DMO on secretin-stimulated pancreatic secretion, DMO was given intravenously to dogs with pancreatic fistulae at a dose of 50, 100 and 200 mg/kg. DMO was promptly excreted into pancreatic juice; the co...
journal_title:Journal of gastroenterology and hepatology
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doi:10.1111/j.1440-1746.1994.tb01279.x
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abstract:BACKGROUND:There are few detailed clinical reports about extrahepatic metastases of hepatocellular carcinoma (HCC). The purpose of the present study was to elucidate the clinical features of extrahepatic metastases of HCC. METHODS:The clinical records of 482 patients who had been diagnosed as having HCC during the per...
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pub_type: 杂志文章
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pub_type: 杂志文章,meta分析
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journal_title:Journal of gastroenterology and hepatology
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doi:10.1046/j.1440-1746.2003.02926.x
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pub_type: 杂志文章,评审
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journal_title:Journal of gastroenterology and hepatology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章,meta分析
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.2010.06564.x
更新日期:2011-04-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.2007.05247.x
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章,多中心研究
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更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-05-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.1996.tb00308.x
更新日期:1996-07-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.2008.05544.x
更新日期:2009-02-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
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doi:10.1046/j.1440-1746.2001.02558.x
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.1992.tb00978.x
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doi:10.1111/j.1440-1746.1991.tb00867.x
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journal_title:Journal of gastroenterology and hepatology
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.2007.05267.x
更新日期:2008-06-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.2005.03831.x
更新日期:2005-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-07-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.2008.05762.x
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
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更新日期:2015-12-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
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更新日期:2013-04-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/jgh.14368
更新日期:2019-04-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章,评审
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更新日期:2006-10-01 00:00:00
abstract:BACKGROUND AND AIM:A recent study in Indian subjects suggested common variants in apolipoprotein C3 (APOC3) (T-455C at rs2854116 and C-482T at rs2854117) to contribute to non-alcoholic fatty liver disease (NAFLD), plasma apoC3 and triglyceride concentrations. Our aim was to determine the contribution of genetic variati...
journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.2011.07045.x
更新日期:2012-05-01 00:00:00