Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease.

abstract：BACKGROUND AND AIMS:Liver biopsy is the gold standard test to determine the grade of fibrosis, but there are associated problems. Because gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid is secreted partially in hepatocytes and bile, it is possible that ethoxybenzyl-magnetic resonance imaging (EOB-MRI) corre...

journal_title：Journal of gastroenterology and hepatology

authors： Nojiri S,Kusakabe A,Fujiwara K,Shinkai N,Matsuura K,Iio E,Miyaki T,Joh T

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The efficiency of Helicobacter pylori eradication varies geographically, as do many parameters that might affect therapeutic efficiency. The aims of this study were to investigate the relationship between different genotypes of H. pylori and bacterium-related histopathological lesions in patients with duoden...

journal_title：Journal of gastroenterology and hepatology

authors： Zhao JJ,Wang JB,Yang L,Li Y

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known about the role of platelet-derived growth factor (PDGF) in biliary fibrosis in the setting of bacterial colonization of the biliary tree. We therefore sought to investigate whether exposure to bacterial lipopolysaccharide (LPS) alters PDGF isoform and receptor expression in cultured r...

journal_title：Journal of gastroenterology and hepatology

authors： Kim TH,Moon JH,Savard CE,Kuver R,Lee SP

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The (13)C-urea breath test ((13)C-UBT) is a reliable non-invasive method of diagnosing Helicobacter pylori infection in adults and children. However, only a few validation studies have been performed on the (13)C-UBT in very young children. The purpose of the present study was to evaluate the diagno...

journal_title：Journal of gastroenterology and hepatology

authors： Yang HR,Seo JK

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:It has been reported that cathepsin E (CTSE) is a non-secretory and intracellular aspartic proteinase found in the superficial epithelial cells of the stomach and that it is also expressed in pancreatic ductal adenocarcinoma. We evaluated the diagnostic value of CTSE in the pancreatic juice in the diagnosis ...

journal_title：Journal of gastroenterology and hepatology

authors： Uno K,Azuma T,Nakajima M,Yasuda K,Hayakumo T,Mukai H,Sakai T,Kawai K

更新日期：2000-11-01 00:00:00

abstract：:Typhoid fever is often associated with abnormal liver biochemical tests, but severe hepatic involvement with a clinical feature of acute hepatitis is a rare complication. There have been more than 150 cases of salmonella hepatitis reported from both developed and developing countries. The documented incidence varies w...

journal_title：Journal of gastroenterology and hepatology

authors： Pramoolsinsap C,Viranuvatti V

更新日期：1998-07-01 00:00:00

abstract：:To investigate the efficacy of standard and low dosage of omeprazole in the healing of duodenal ulcer, 270 patients with endoscopically active duodenal ulcer were randomized to receive omeprazole, 10 mg or 20 mg every morning, or ranitidine, 150 mg twice daily, using the double-dummy technique. Forty-six potential pro...

journal_title：Journal of gastroenterology and hepatology

authors： Hui WM,Lam SK,Lau WY,Branicki FJ,Lok AS,Ng MM,Lai CL,Poon GP

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND AND AIM:Little is known whether routine prophylaxis against Pneumocystis jirovecii pneumonia (PJP) is needed in patients with inflammatory bowel disease (IBD) on immunosuppression, especially in Asian populations. We, therefore, sought to investigate the incidence and risk factors of PJP in patients with IBD...

journal_title：Journal of gastroenterology and hepatology

authors： Nam K,Park SH,Lee J,Jo S,Kim SO,Noh S,Park JC,Kim JY,Kim J,Ham NS,Oh EH,Song EM,Hwang SW,Yang DH,Ye BD,Byeon JS,Myung SJ,Yang SK

更新日期：2020-02-01 00:00:00

abstract：:To investigate the effect of hepatitis delta virus (HDV) superinfection on the long-term outcome of Japanese subjects with chronic hepatitis B virus (HBV) infection, we examined the presence of antibodies to hepatitis delta antigen (anti-HD) in serial serum samples collected from 1127 subjects with chronic HBV infecti...

journal_title：Journal of gastroenterology and hepatology

authors： Tamura I,Kurimura O,Koda T,Ichimura H,Katayama S,Kurimura T,Inaba Y

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The role of Helicobacter pylori infection in gastroduodenal lesions might be different between the general population and AIDS patients. The aim of the present study was to compare the prevalence of H. pylori and cytomegalovirus (CMV) infection in AIDS patients and HIV-negative controls. The impact ...

journal_title：Journal of gastroenterology and hepatology

authors： Chiu HM,Wu MS,Hung CC,Shun CT,Lin JT

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND AND AIM:The major transporter responsible for bile acid uptake from the intestinal lumen is the apical sodium-dependent bile acid transporter (ASBT, SLC10A2). Analysis of the SLC10A2 gene has identified a variety of sequence variants including coding region single nucleotide polymorphisms (SNPs) that may inf...

journal_title：Journal of gastroenterology and hepatology

authors： Ho RH,Leake BF,Urquhart BL,Gregor JC,Dawson PA,Kim RB

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIM:The differentiation between Crohn's disease (CD) and tuberculosis (TB) of the intestine can be difficult in areas where both diseases occur. The present study examined histological criteria that would enable the diagnosis in mucosal biopsies. METHODS:Colonoscopic biopsies from 33 patients with TB an...

journal_title：Journal of gastroenterology and hepatology

authors： Pulimood AB,Peter S,Ramakrishna B,Chacko A,Jeyamani R,Jeyaseelan L,Kurian G

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Interstitial cells of Cajal (ICCs), which express c-Kit receptor tyrosine kinase (KIT), play an important role in gastrointestinal motility. Loss of ICCs likely contributes to diabetic gastrointestinal motility disorder, however, the mechanism of attrition remains unknown. Here, we test the hypothesis that t...

journal_title：Journal of gastroenterology and hepatology

authors： Li Y,Kojima H,Fujino K,Matsumura K,Katagi M,Urabe H,Chan L,Eguchi Y,Zhao L,Kimura H

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Absolute lymphocyte count (ALC) and the recovery of ALC after treatment have been identified as a prognostic biomarker for several malignancies. In this study, we aimed to investigate the prognostic role of peritransplant ALC and ALC recovery after liver transplantation (LT) in hepatocellular carcin...

journal_title：Journal of gastroenterology and hepatology

authors： Zheng Z,Lin B,Zhang J,Yang Z,Xie H,Zhou L,Zhang M,Zheng S

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Annexin A10 (ANXA10) and its liver-specific short isoform (ANXA10S) had tissue-restricted expression. The downregulation of ANXA10S is correlated with tumor progression and poor prognosis in hepatocellular carcinoma. The aim of the present study was to validate the tissue distribution and explore th...

journal_title：Journal of gastroenterology and hepatology

authors： Lu SH,Chen YL,Shun CT,Lai JN,Peng SY,Lai PL,Hsu HC

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND AND AIM:The stool antigen test, the HpSA test, has been validated mainly in Western countries, but not properly in the Chinese population. Recently, another stool antigen test, the Apollo test, was developed, but its accuracy has rarely been validated. The aim of this study is to compare the accuracy of thes...

journal_title：Journal of gastroenterology and hepatology

authors： Wong BC,Xia HH,Cheung HK,Ng FH,Wong SY,Chow KC,Lin SK,Yin Y,Wong WM,Yuen MF,Lam SK

更新日期：2003-01-01 00:00:00

abstract：:A hepatitis B virus (HBV) carrier with marked retention of indocyanine green (ICG) and sulfobromophthalein (BSP) was admitted to our hospital for assessment of liver function. On admission, he was asymptomatic and blood chemistry tests showed normal values for transaminases and bilirubin. Serum hepatitis B surface ant...

journal_title：Journal of gastroenterology and hepatology

authors： Ikejima K,Ichikawa S,Kitamura T,Watanabe S,Hirose M,Yokoi Y,Uchida S,Oide H,Suzuki H,Kitami N

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND AND AIM:Reactive oxygen species produced by cytochrome P4502E1 (CYP2E1) are believed to play a role in pathophysiology of non-alcoholic fatty liver disease (NAFLD). However, little is known about the expression, protein content and activity of anti-oxidant enzymes and the role of inducible nitric oxide synth...

journal_title：Journal of gastroenterology and hepatology

authors： Kathirvel E,Chen P,Morgan K,French SW,Morgan TR

更新日期：2010-06-01 00:00:00

abstract：:Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. This case of a 65-year-old Korean man with HCC and metastatic frontal bone mass that regressed after radiotherapy for frontal bone mass without any other therapeutic modalities is described. The clinical diagnosis of HCC was made because of...

journal_title：Journal of gastroenterology and hepatology

authors： Nam SW,Han JY,Kim JI,Park SH,Cho SH,Han NI,Yang JM,Kim JK,Choi SW,Lee YS,Chung KW,Sun HS

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Mongolian gerbils are frequently used to study Helicobacter pylori-induced gastritis and its consequences. The presence of some gastric flora with a suppressive effect on H. pylori suggests inhibitory microflora against H. pylori infection. The aim of the present study was to analyze the microflora ...

journal_title：Journal of gastroenterology and hepatology

authors： Zaman C,Osaki T,Hanawa T,Yonezawa H,Kurata S,Kamiya S

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND AND AIM:Radiation-induced colitis is a common clinical problem associated with radiotherapy and accidental exposure to ionizing radiation. Goblet cells play a pivotal role in the intestinal barrier against pathogenic bacteria. Rebamipide, an anti-gastric ulcer drug, has the effects to promote goblet cell pro...

journal_title：Journal of gastroenterology and hepatology

authors： Jang H,Park S,Lee J,Myung JK,Jang WS,Lee SJ,Myung H,Lee C,Kim H,Lee SS,Jin YW,Shim S

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic screening for esophageal varices (EVs) is expensive and invasive. Besides traditional noninvasive markers, we explore additional candidate markers including portal hypertension serum marker-soluble CD136 (sCD163) and genetic variants of splanchnic vasodilatation and revascularization pathw...

journal_title：Journal of gastroenterology and hepatology

authors： Yang YY,Hou MC,Lin MW,Chen PH,Liao WC,Chu CJ,Lin HC

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIM:This study investigated the usefulness of near-focus narrowband imaging (NF-NBI) for determining gastric tumor margins compared with indigo carmine chromoendoscopy (ICC) before endoscopic submucosal dissection (ESD). METHODS:This prospective randomized controlled trial was conducted at seven teachin...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JW,Jung Y,Jang JY,Kim GH,Bang BW,Park JC,Choi HS,Cho JH,Research Group for Endoscopic Instruments and Stents of Korean Society of Gastrointestinal Endoscopy.

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND AND AIM:Products of the arachidonic acid metabolizing enzyme, 5-lipoxygenase (5-LOX), stimulate the growth of several cancer types. Inhibitors of 5-LOX and 5-LOX-activating protein (FLAP) induce apoptosis in some cancer cells. Here, the authors investigated the effect of a FLAP inhibitor, MK-886, on the inhi...

journal_title：Journal of gastroenterology and hepatology

authors： Fan XM,Tu SP,Lam SK,Wang WP,Wu J,Wong WM,Yuen MF,Lin MC,Kung HF,Wong BC

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND AND AIMS:We have shown previously that concentrations of stool decay-accelerating factor (DAF; CD55), a complement regulatory protein, in patients with ulcerative colitis (UC) are increased in relation to the severity of the colonic mucosal inflammation. In the present study, we evaluated the usefulness of s...

journal_title：Journal of gastroenterology and hepatology

authors： Kohno H,Mizuno M,Nasu J,Makidono C,Hiraoka S,Inaba T,Yamamoto K,Okada H,Fujita T,Shiratori Y

更新日期：2005-01-01 00:00:00

abstract：:The anti-pre-S antibody in the samples of sera from normal healthy persons and patients with different clinical types of liver diseases due to hepatitis B virus (HBV) infection was detected by a newly established enzyme-linked immunosorbent assay technique. This test is a blocking assay where anti-pre-S antibody in th...

journal_title：Journal of gastroenterology and hepatology

authors： Irshad M,Gandhi BM,Acharya SK,Joshi YK,Tandon BN

更新日期：1989-01-01 00:00:00

abstract：:In order to detect both pancreatic excretion of dimethadione (DMO), a weak organic acid, and the effect of pancreatic DMO on secretin-stimulated pancreatic secretion, DMO was given intravenously to dogs with pancreatic fistulae at a dose of 50, 100 and 200 mg/kg. DMO was promptly excreted into pancreatic juice; the co...

journal_title：Journal of gastroenterology and hepatology

authors： Noda A,Takeuchi K,Murayama H,Ibuki E,Okumura I,Okuyama M,Okayama T,Kobayashi T

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Toll-like receptors (TLRs) are involved in innate immunity. Certain viruses interact with TLRs and mediate antiviral effects as well as immune responses. The aim of this study was to investigate the effect of TLRs on pathogenesis in hepatitis C virus (HCV)-infected patients. METHODS:Peripheral blood mononuc...

journal_title：Journal of gastroenterology and hepatology

authors： Sato K,Ishikawa T,Okumura A,Yamauchi T,Sato S,Ayada M,Matsumoto E,Hotta N,Oohashi T,Fukuzawa Y,Kakumu S

更新日期：2007-10-01 00:00:00

abstract：:The main goals of chronic hepatitis B treatment should be the long-term suppression of viral replication to minimize disease progression and the risk for the development of hepatocellular carcinoma. Treatment end-points, depending on surrogate markers alone, in particular hepatitis B e-antigen seroconversion, may not ...

journal_title：Journal of gastroenterology and hepatology

authors： Fung J,Lai CL,Yuen MF

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND AND AIM:The significance of serum levels of transforming growth factor (TGF)-beta1 in the development of gastric cancer is unclear. The purpose of this study is to determine whether serum TGF-beta1 correlated with the clinicopathological findings of patients with gastric cancer. METHODS:Transforming growth ...

journal_title：Journal of gastroenterology and hepatology

authors： Lin Y,Kikuchi S,Obata Y,Yagyu K,Tokyo Research Group on Prevention of Gastric Cancer.

更新日期：2006-02-01 00:00:00