Marked retention of indocyanine green and sulfobromophthalein with chronic persistent hepatitis.

Abstract:

:A hepatitis B virus (HBV) carrier with marked retention of indocyanine green (ICG) and sulfobromophthalein (BSP) was admitted to our hospital for assessment of liver function. On admission, he was asymptomatic and blood chemistry tests showed normal values for transaminases and bilirubin. Serum hepatitis B surface antigen (HBsAg) and antibody to hepatitis B e antigen (anti-HBe) were positive. A history of drug abuse or alcoholism was denied. Dye excretion tests revealed marked retention of ICG (R15 = 70%) and BSP (R45 = 23%). Histopathological examination of a liver biopsy specimen obtained during laparoscopic observation showed chronic persistent hepatitis (CPH). Familial research of the patient failed to prove the existence of dye excretory defect in his siblings. Usual cases of CPH due to continuous HBV infection do not show such severe disturbance of organic anion transport. This pattern of the dye excretory defect with CPH has not been reported. Although the relationship between this dye excretory defect and HBV infection is unclear, the existence of the constitutional dye excretory defect due to abnormal organic anion transport in the liver might be considered.

authors

Ikejima K,Ichikawa S,Kitamura T,Watanabe S,Hirose M,Yokoi Y,Uchida S,Oide H,Suzuki H,Kitami N

doi

10.1111/j.1440-1746.1993.tb01554.x

subject

Has Abstract,Author List Incomplete

pub_date

1993-09-01 00:00:00

pages

489-94

issue

5

eissn

0815-9319

issn

1440-1746

journal_volume

8

pub_type

杂志文章
  • Epidemiology of Helicobacter pylori and peptic ulcer in India.

    abstract:BACKGROUND:There is a wide variation in the prevalence of peptic ulcer in India both before and since the use of endoscopy. We studied the prevalence of peptic ulcer disease in a community in northern India and its relationship with Helicobacter pylori infection. METHODS:A house-to-house survey of residents aged 15 ye...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2002.02746.x

    authors: Singh V,Trikha B,Nain CK,Singh K,Vaiphei K

    更新日期:2002-06-01 00:00:00

  • Oral manifestations in patients with familial adenomatous polyposis: A systematic review and meta-analysis.

    abstract:BACKGROUND AND AIM:The oral manifestations of familial adenomatous polyposis (FAP) have been reported in the recent literature. Therefore, there has been growing interest in the characterization of the dento-osseous anomalies because they may precede colorectal cancer and may be used as a diagnostic marker. This system...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/jgh.13149

    authors: Almeida FT,Pachêco-Pereira C,Porporatti AL,Flores-Mir C,Leite AF,De Luca Canto G,Guerra EN

    更新日期:2016-03-01 00:00:00

  • Immunological alterations in pregnant women with acute hepatitis E.

    abstract:BACKGROUND:Infection with hepatitis E virus (HEV) is a major cause of acute viral hepatitis in several developing countries. Although usually self-limiting and benign, the disease is particularly severe among pregnant women, with mortality rates reaching 15-20%. METHODS:Immune parameters among pregnant women with acut...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2005.03875.x

    authors: Pal R,Aggarwal R,Naik SR,Das V,Das S,Naik S

    更新日期:2005-07-01 00:00:00

  • The efficacy of oral Zhizhu Kuanzhong, a traditional Chinese medicine, in patients with postprandial distress syndrome.

    abstract:BACKGROUND AND AIM:The treatment of patients with functional dyspepsia (FD) remains unsatisfactory. We assessed the efficacy of Zhizhu Kuanzhong (ZZKZ) capsule, a traditional Chinese medicine formula, in patients with postprandial distress syndrome (PDS) of FD. METHODS:The study was designed as a multicenter, randomiz...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/jgh.14467

    authors: Xiao Y,Li Y,Shu J,Li Y,Xu J,Ren J,Liu D,Wang J,Zhou L,Li Y,Tang G,Tian D,Zhang S,Hou X,Wang H,Li Z,Lv N,Chen M

    更新日期:2019-03-01 00:00:00

  • Assessment of cytology and mucin 2 in colorectal mucus collected from patients with inflammatory bowel disease: Results of a pilot trial.

    abstract:BACKGROUND AND AIM:Non-invasive diagnosis of colorectal disease remains problematic, fecal biomarkers presenting the only current option. Colorectal mucus is the diagnostically informative element of stool samples, but its separation from stool is difficult. We aimed to: (i) test a novel method of non-invasive colorect...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.13083

    authors: Loktionov A,Chhaya V,Bandaletova T,Poullis A

    更新日期:2016-02-01 00:00:00

  • Effectiveness of chemical biliary duct embolization for chemical hepatectomy.

    abstract:BACKGROUND AND AIMS:The high recurrence of hepatolithiasis and high operative trauma of hepatectomy necessitate new therapeutic approaches. Thus, this study was designed to (i) investigate the effectiveness of chemical biliary duct embolization (CBDE) for chemical hepatectomy; and (ii) to determine the mechanism of CBD...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2005.04090.x

    authors: Li FY,Cheng JQ,Li N,He S,Zhang MM,Dong JH,Jiang LS,Cheng NS

    更新日期:2006-05-01 00:00:00

  • Laurence-Moon-Biedl syndrome accompanied by congenital hepatic fibrosis.

    abstract::A 33 year old woman with mental deficiency, retinitis pigmentosa, obesity, and parental consanguinity (heredity) was diagnosed as having Laurence-Moon-Biedl syndrome. She also had diabetes mellitus, slight hepatic dysfunction, and hepatomegaly. Liver biopsy showed perilobular fibrosis and bile duct proliferation with ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1990.tb01826.x

    authors: Nakamura F,Sasaki H,Kajihara H,Yamanoue M

    更新日期:1990-03-01 00:00:00

  • Utility of baseline positron emission tomography with computed tomography for predicting endoscopic resectability and survival outcomes in patients with early esophageal adenocarcinoma.

    abstract:BACKGROUND AND AIMS:Positron emission tomography with computed tomography (PET/CT) has been used to detect metastasis in the diagnosis of esophageal adenocarcinoma (EAC). However, the utility of PET/CT to assess primary tumor for endoscopic resectability and prognosis in early EAC remains unclear. We conducted a retros...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12148

    authors: Sun G,Tian J,Gorospe EC,Johnson GB,Hunt CH,Lutzke LS,Leggett CL,Iyer PG,Wang KK

    更新日期:2013-06-01 00:00:00

  • Narrowband imaging with near-focus magnification for discriminating the gastric tumor margin before endoscopic resection: A prospective randomized multicenter trial.

    abstract:BACKGROUND AND AIM:This study investigated the usefulness of near-focus narrowband imaging (NF-NBI) for determining gastric tumor margins compared with indigo carmine chromoendoscopy (ICC) before endoscopic submucosal dissection (ESD). METHODS:This prospective randomized controlled trial was conducted at seven teachin...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.15109

    authors: Kim JW,Jung Y,Jang JY,Kim GH,Bang BW,Park JC,Choi HS,Cho JH,Research Group for Endoscopic Instruments and Stents of Korean Society of Gastrointestinal Endoscopy.

    更新日期:2020-11-01 00:00:00

  • Evaluation of two stool antigen tests for the detection of Helicobacter pylori infection in the Chinese population.

    abstract:BACKGROUND AND AIM:The stool antigen test, the HpSA test, has been validated mainly in Western countries, but not properly in the Chinese population. Recently, another stool antigen test, the Apollo test, was developed, but its accuracy has rarely been validated. The aim of this study is to compare the accuracy of thes...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2003.02926.x

    authors: Wong BC,Xia HH,Cheung HK,Ng FH,Wong SY,Chow KC,Lin SK,Yin Y,Wong WM,Yuen MF,Lam SK

    更新日期:2003-01-01 00:00:00

  • Coffee and non-alcoholic fatty liver disease: brewing evidence for hepatoprotection?

    abstract::Coffee is one of the most popular beverages in the world. Several studies consistently show that coffee drinkers with chronic liver disease have a reduced risk of cirrhosis and a lower incidence of hepatocellular carcinoma regardless of primary etiology. With the increasing prevalence of non-alcoholic fatty liver dise...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/jgh.12422

    authors: Chen S,Teoh NC,Chitturi S,Farrell GC

    更新日期:2014-03-01 00:00:00

  • The epidemiology of inflammatory bowel disease: East meets west.

    abstract::The incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade to become a global disease. The increasing number of studies on the incidence and course of IBD in East has enabled us to explore East versus West differences in the epidemiology of IBD which could enhance our understanding of th...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/jgh.14872

    authors: Mak WY,Zhao M,Ng SC,Burisch J

    更新日期:2020-03-01 00:00:00

  • Peginterferon alpha-2a (40 KD) plus ribavirin for the treatment of chronic hepatitis C in Japanese patients.

    abstract:BACKGROUND:The efficacy and safety of peginterferon alpha-2a (40 KD) (peg-IFNalpha-2a) plus ribavirin has not been reported for Japanese patients with chronic hepatitis C. The aim of this study was to evaluate this combination in treatment-naïve patients and in non-responders or relapsers to interferon monotherapy. ME...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1440-1746.2007.04834.x

    authors: Kuboki M,Iino S,Okuno T,Omata M,Kiyosawa K,Kumada H,Hayashi N,Sakai T

    更新日期:2007-05-01 00:00:00

  • Clinical impact of HFE mutations in Japanese patients with chronic hepatitis C.

    abstract:BACKGROUND AND AIM:HFE mutations, a common cause of hereditary hemochromatosis (HH), are reportedly associated with hepatic iron overload, severe liver fibrosis, and good response to interferon treatment in European patients with chronic hepatitis C (CHC). HH shows ethnicity-based differences and little is known about ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2011.06976.x

    authors: Ishizu Y,Katano Y,Honda T,Hayashi K,Ishigami M,Itoh A,Hirooka Y,Nakano I,Goto H

    更新日期:2012-06-01 00:00:00

  • Risk of alanine aminotransferase flare-up among asymptomatic hepatitis C virus RNA carriers: a 10-year follow-up study.

    abstract:AIMS:The aim of this study was to determine the cumulative rate of flare-up of serum alanine aminotransferase (ALT) level during a 10-year follow-up period, and characterize the clinical, virologic features in 120 hepatitis C virus (HCV) RNA-positive asymptomatic carriers with persistently normal ALT levels for 6 month...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2001.02474.x

    authors: Tsuji K,Yamasaki K,Yamanishi M,Kawakami M,Shirahama S

    更新日期:2001-05-01 00:00:00

  • Intraductal ultrasonography for hepatocellular carcinoma with tumor thrombi in the bile duct: comparison with polypoid cholangiocarcinoma.

    abstract:BACKGROUND AND AIM:Tumor thrombi in the bile duct caused by hepatocellular carcinoma (HCC), and cholangiocarcinoma show polypoid lesions on cholangiographic findings. This study prospectively compared the images of intraductal ultrasonography between HCC and polypoid cholangiocarcinoma. METHODS:In five patients with t...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.2001.02527.x

    authors: Tamada K,Isoda N,Wada S,Tomiyama T,Ohashi A,Satoh Y,Ido K,Sugano K

    更新日期:2001-07-01 00:00:00

  • Two histologic compartments in nonpolypoid conventional colon adenomas.

    abstract::Two intertwined compartments coexisting in nonpolypoid conventional (i.e. tubular or villous) adenomas are highlighted in this review: one built of dysplastic tissue on top and the other portraying crypts with irregular, corrupted shapes, albeit lined with normal epithelium, below. The latter compartment has remained ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章,评审

    doi:10.1111/jgh.15210

    authors: Rubio CA

    更新日期:2020-08-05 00:00:00

  • Impact of immunomodulator use on treatment persistence in patients with ulcerative colitis: A claims database analysis.

    abstract:BACKGROUND AND AIM:It is unclear how adding an anti-tumor necrosis factor alpha agent to immunomodulator (IM) treatment, as a step-up strategy, affects long-term outcomes in ulcerative colitis. This retrospective study investigated persistence associated with biologic anti-tumor necrosis factor alpha agents combined wi...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.14825

    authors: Kobayashi T,Udagawa E,Uda A,Hibi T,Hisamatsu T

    更新日期:2020-02-01 00:00:00

  • Intracellular mechanisms underlying lipid accumulation (white opaque substance) in gastric epithelial neoplasms: A pilot study of expression profiles of lipid-metabolism-associated genes.

    abstract:BACKGROUND AND AIM:White opaque substance (WOS) is a novel endoscopic finding in gastric neoplasms, indicating the intracellular accumulation of lipid droplets (LDs). However, gastric lipid metabolism has not been extensively investigated, even in normal mucosa. We investigated the expression profiles of lipid-metaboli...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.13216

    authors: Enjoji M,Kohjima M,Ohtsu K,Matsunaga K,Murata Y,Nakamuta M,Imamura K,Tanabe H,Iwashita A,Nagahama T,Yao K

    更新日期:2016-04-01 00:00:00

  • Persistent ileitis after ileal salvage from a failed Kock pouch.

    abstract::A case of persistent ileitis following the refashioning of a Kock ileal pouch into a Brooke ileostomy for severe pouchitis is reported. Preserving the terminal ileum by a salvage procedure may not be a safe alternative to pouch excision with the formation of a new end ileostomy in the surgical management of pouchitis ...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1992.tb00999.x

    authors: de Silva HJ,Mortensen NJ

    更新日期:1992-07-01 00:00:00

  • Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-alpha gene promoter polymorphisms.

    abstract:BACKGROUND:The reasons for the viral persistence of hepatitis B virus infection (HBV) are unknown, but are probably related to host immune factors. Cytokines play a significant role in immune defense. The present study was undertaken to investigate the association between HBV infection and polymorphisms of tumor necros...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2006.04304.x

    authors: Cheong JY,Cho SW,Hwang IL,Yoon SK,Lee JH,Park CS,Lee JE,Hahm KB,Kim JH

    更新日期:2006-07-01 00:00:00

  • Attitudes and knowledge of colorectal cancer and screening in Hong Kong: a population-based study.

    abstract:BACKGROUND:Colorectal cancer (CRC) ranks third of all cancer mortalities in Hong Kong. CRC screening can reduce mortality. However, participation in the CRC screening program depends on the knowledge and attitude of the population. The aim of this study is to investigate the knowledge and attitude towards CRC screening...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.2005.04000.x

    authors: Wong BC,Chan AO,Wong WM,Hui WM,Kung HF,Lam SK

    更新日期:2006-01-01 00:00:00

  • Presence of spur cells as a highly predictive factor of mortality in patients with cirrhosis.

    abstract:BACKGROUND AND AIM:The presence of spur-cell anemia (SCA) is due to lipid disturbances of the erythrocyte membrane and may develop in patients with advanced liver cirrhosis. The accurate predicting value of SC for survival has not been clarified. The aim of this study was to evaluate SCA as a prognostic indicator in pa...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/jgh.12473

    authors: Alexopoulou A,Vasilieva L,Kanellopoulou T,Pouriki S,Soultati A,Dourakis SP

    更新日期:2014-04-01 00:00:00

  • A prospective and comparative cohort study on efficacy and drug resistance during long-term lamivudine treatment for various stages of chronic hepatitis B and cirrhosis.

    abstract:BACKGROUND AND AIMS:A prospective, non-randomized cohort study on long-term lamivudine treatment, comparing efficacy, drug resistance, and prognosis for various stages of chronic hepatitis B virus (HBV)-related liver disease was performed to elucidate the significance and indication of lamivudine for individual patient...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/j.1440-1746.2007.05240.x

    authors: Nishida T,Kobashi H,Fujioka S,Fujio K,Takaguchi K,Ikeda H,Kawaguchi M,Ando M,Araki Y,Higashi T,Shoji B,Takaki A,Iwasaki Y,Sakaguchi K,Shiratori Y,Yamamoto K

    更新日期:2008-05-01 00:00:00

  • Case report: hypoechoic submucosal nodules: a sign of Epstein-Barr virus-associated early gastric cancer.

    abstract::The Epstein-Barr virus (EBV) has been reported to be detectable in about 10% of gastric carcinomas. We performed a comparative study of endosonographic findings of EBV-positive and -negative early gastric carcinomas. Epstein-Barr virus was detected in 11.8% (four of 34) of endosonographically observed early gastric ca...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1998.tb00694.x

    authors: Nishikawa J,Yanai H,Mizugaki Y,Takada K,Tada M,Okita K

    更新日期:1998-06-01 00:00:00

  • Haemosuccus pancreaticus: a clinical challenge.

    abstract:BACKGROUND:Haemosuccus pancreaticus is a rare complication of pancreatitis. It is a diagnostic problem for even the most astute clinician and a challenge for the expert endoscopist. We report a 25-year-old male patient who had all the features usually seen in haemosuccus pancreaticus patients: recurrent obscure upper g...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.1999.01834.x

    authors: Yattoo GN,Khuroo MS,Wani NA,Wani KA,Bhat FA

    更新日期:1999-02-01 00:00:00

  • Endoscopic management of acute calculous cholangitis.

    abstract::Acute cholangitis is associated with significant morbidity and mortality. Endoscopic drainage procedures have been shown to be a safe and effective mode of treatment in acute cholangitis. As there is paucity of large series on endoscopic management of acute cholangitis, a study was performed to evaluate safety and eff...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1440-1746.1997.tb00386.x

    authors: Sharma BC,Agarwal DK,Baijal SS,Saraswat VA,Choudhuri G,Naik SR

    更新日期:1997-12-01 00:00:00

  • Echo-Doppler measurements of portal vein and superior mesenteric artery blood flow in humans: inter- and intra-observer short-term reproducibility.

    abstract::The reproducibility of echo-Doppler measurements of portal vein and superior mesenteric artery blood flow has not been extensively studied. In the present study, two groups of subjects were examined to test inter- and intra-observer reproducibility. Each study population consisted of 15 nonportal hypertensive and 15 p...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1996.tb00008.x

    authors: Iwao T,Toyonaga A,Shigemori H,Oho K,Sumino M,Sato M,Tanikawa K

    更新日期:1996-01-01 00:00:00

  • Analysis of HLA alleles in Japanese patients with cirrhosis due to chronic hepatitis C.

    abstract::Hepatitis C virus (HCV) leads to chronic liver disease in at least 50-60% of infected people and approximately 40-50% of these patients will go on to develop cirrhosis due to chronic hepatitis C (HCV-C). The pathogenic mechanisms that result in HCV-C are unknown. Sixty Japanese patients with HCV-C were examined for HL...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1111/j.1440-1746.1996.tb00069.x

    authors: Higashi Y,Kamikawaji N,Suko H,Ando M

    更新日期:1996-03-01 00:00:00

  • Anorectal physiology and transit in patients with disorders of thyroid metabolism.

    abstract:BACKGROUND:Data on anorectal physiology in patients with disordered thyroid metabolism are lacking. This prospective study was performed to evaluate anorectal physiology in patients with either hyperthyroidism and diarrhoea, or hypothyroidism and constipation in order to assess slow transit in hypothyroid patients. ME...

    journal_title:Journal of gastroenterology and hepatology

    pub_type: 杂志文章

    doi:10.1046/j.1440-1746.1999.01865.x

    authors: Deen KI,Seneviratne SL,de Silva HJ

    更新日期:1999-04-01 00:00:00