The association between non-alcoholic fatty liver disease (with or without metabolic syndrome) and extrahepatic cancer development.

abstract：BACKGROUND:Oxidative stress plays an important role in the pathogenesis of chronic liver diseases. The plasma level of 8-isoprostane, a product of lipid peroxidation, is a marker of oxidative stress in vivo. The aim of the present study was to clarify whether the degree of lipid peroxidation, as measured by the plasma ...

journal_title：Journal of gastroenterology and hepatology

authors： Konishi M,Iwasa M,Araki J,Kobayashi Y,Katsuki A,Sumida Y,Nakagawa N,Kojima Y,Watanabe S,Adachi Y,Kaito M

更新日期：2006-12-01 00:00:00

abstract：:Despite steady progress in antiviral treatment for patients with chronic hepatitis C virus(HCV), many patients still have detectable serum HCV RNA levels by the end of interferon-based treatment and are known as virological non-responders. Re-treatment of these patients not responding to previous therapy remains chall...

journal_title：Journal of gastroenterology and hepatology

authors： Poo JL,Sánchez-Avila F,Kershenobich D,García-Samper X,Gongora J,Uribe M

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND AND AIM:The high-mobility group box 1 (HMGB1) protein plays an important role in a lot of biological behaviors, including DNA damage repair, gene transcription, cell replication, and cell death, and its expression is higher in many solid tumors tissues than in their adjacent normal tissues, and it is always ...

journal_title：Journal of gastroenterology and hepatology

authors： Di X,He G,Chen H,Zhu C,Qin Q,Yan J,Zhang X,Sun X

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND AND AIM:The present study was designed to investigate the expression of and humoral response against NY-ESO-1 in patients with hepatocellular carcinoma and to analyze the relationship between expression of NY-ESO-1 mRNA and clinicopathological features. METHODS:NY-ESO-1 mRNA and protein expression in surgic...

journal_title：Journal of gastroenterology and hepatology

authors： Nakamura S,Nouso K,Noguchi Y,Higashi T,Ono T,Jungbluth A,Chen YT,Old LJ,Nakayama E,Shiratori Y

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The present study examined the effects of NS-398, a specific cyclo-oxygenase-2 inhibitor, on gastric mucosal cell kinetics and gastric wound healing following acid-induced injury. METHODS:Male Sprague-Dawley rats were fasted for 24 h and then 0.6 mol/L hydrochloric acid (HCl; 1 mL) was administered...

journal_title：Journal of gastroenterology and hepatology

authors： Sun WH,Tsuji S,Tsujii M,Gunawan ES,Sawaoka H,Kawai N,Iijima H,Kimura A,Kakiuchi Y,Yasumaru M,Sasaki Y,Kawano S,Hori M

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Although capsule endoscopy (CE) is widely used as a first-line diagnostic modality for obscure gastrointestinal bleeding (OGIB), the rebleeding rate after negative CE varies according to different studies. We tried to elucidate the outcomes after negative CE for OGIB and to determine the risk factor...

journal_title：Journal of gastroenterology and hepatology

authors： Kim JB,Ye BD,Song Y,Yang DH,Jung KW,Kim KJ,Byeon JS,Myung SJ,Yang SK,Kim JH

更新日期：2013-05-01 00:00:00

abstract：:Bioactive food chemicals are substances present in food that are capable of interacting with living cells causing changes in physiological functions. Salicylic acid (SA), a plant hormone involved in plant immune response, is one such bioactive food chemical. Aspirin, a commercially available SA, might play beneficial ...

journal_title：Journal of gastroenterology and hepatology

authors： Malakar S

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND AND AIM:In Japan, peptic ulcer disease (PUD) is treated clinically with a combination of a mucosal protectant and acid suppressants, but there is scant information regarding the effects of these drugs on normal gastric mucus cells. In the present study, the effects of co-administration of methylmethionine su...

journal_title：Journal of gastroenterology and hepatology

authors： Ichikawa T,Ito Y,Saegusa Y,Iwai T,Goso Y,Ikezawa T,Ishihara K

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND AIM:Incidental pancreatic cystic lesions (PCLs) are being diagnosed more frequently. However, little is known about the prevalence of PCLs in the Chinese population. The aim of the study was to assess the crude prevalence of PCLs in individuals who underwent magnetic resonance imaging (MRI). METHODS:Dat...

journal_title：Journal of gastroenterology and hepatology

authors： Sun L,Wang Y,Jiang F,Qian W,Shao C,Jin Z

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Saccharomyces cerevisiae may contribute to the pathophysiology of Crohn's disease. We determined serum anti-Saccharomyces cerevisiae antibody (ASCA) levels in patients with inflammatory bowel disease. METHODS AND RESULTS:Immunoglobulin G (IgG) ASCA was measured by using an ELISA in serum samples from 19 pat...

journal_title：Journal of gastroenterology and hepatology

authors： Oshitani N,Hato F,Matsumoto T,Jinno Y,Sawa Y,Hara J,Nakamura S,Seki S,Arakawa T,Kitano A,Kitagawa S,Kuroki T

更新日期：2000-12-01 00:00:00

abstract：:Bleeding from hepatocellular carcinoma (HCC) invading the gastrointestinal tract is very uncommon. We report the case of a 61 year old man who had a large bleed from HCC invading the fundus of the stomach. Diagnosis was eventually made at laparotomy and he is still alive 7 months after local resection. ...

journal_title：Journal of gastroenterology and hepatology

authors： Nicoll AJ,Ireton HJ,Crotty B

更新日期：1994-09-01 00:00:00

abstract：AIM:To determine whether liver biopsy might be useful in the diagnosis of visceral leishmaniasis when bone marrow examination and serologic tests are inconclusive. METHODS:Over a 10-year period, liver biopsy was performed in five children with suspected visceral leishmaniasis when indirect hemagglutination tests and b...

journal_title：Journal of gastroenterology and hepatology

authors： Artan R,Yilmaz A,Akçam M,Aksoy NH

更新日期：2006-01-01 00:00:00

abstract：:Primary liver cancer, particularly hepatocellular carcinoma (HCC) remains a significant disease worldwide. It is among the top three causes of cancer death in the Asia Pacific region because of the high prevalence of its main etiological agents, chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. I...

journal_title：Journal of gastroenterology and hepatology

authors： Yuen MF,Hou JL,Chutaputti A,Asia Pacific Working Party on Prevention of Hepatocellular Carcinoma.

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND AND AIM:Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease. Previous studies have investigated the association between dietary patterns and NAFLD, but their results are contradictory. Therefore, we carried out this meta-analysis to examine the association betw...

journal_title：Journal of gastroenterology and hepatology

authors： Hassani Zadeh S,Mansoori A,Hosseinzadeh M

更新日期：2020-12-02 00:00:00

abstract：:Interpretation of exploding knowledge about Barrett's esophagus is impaired by use of several conflicting definitions. Because any histological type of esophageal columnar metaplasia carries risk for esophageal adenocarcinoma, the diagnosis of Barrett's esophagus should no longer require demonstration of intestinal-ty...

journal_title：Journal of gastroenterology and hepatology

authors： Dent J

更新日期：2011-01-01 00:00:00

abstract：:The most frequent benign tumours of the liver include haemangioma, liver cell adenoma and focal nodular hyperplasia. Patients may undergo hepatic resection because of a preoperative diagnosis of malignancy or uncertainty in diagnosis despite an extensive work-up. ...

journal_title：Journal of gastroenterology and hepatology

authors： Chen MF

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Cystinosis is a metabolic disease characterized by accumulation of cystine in different organs and tissues, leading to potentially life-threatening organ dysfunction. Infantile cystinosis typically leads to end-stage renal disease, necessitating renal replacement therapy. Liver disease in cystinosis is rare ...

journal_title：Journal of gastroenterology and hepatology

authors： Cornelis T,Claes K,Gillard P,Nijs E,Roskams T,Lombaerts R,Nevens F,Cassiman D

更新日期：2008-08-01 00:00:00

abstract：:Although the incidence of bleeding from gastric varices is relatively low (10%-36%), the bleeding is massive once it has occurred and it increases the patient's mortality. The management of esophageal variceal bleeding is highly differentiated with several effective treatments available. In contrast, bleeding from gas...

journal_title：Journal of gastroenterology and hepatology

authors： Hashizume M,Akahoshi T,Tomikawa M

更新日期：2011-01-01 00:00:00

abstract：:Better understanding of hepatitis B virus (HBV) replication and the natural history and immunopathogenesis of chronic hepatitis B, together with the introduction of effective agents with different mechanisms of action, is the basis for better therapeutic strategies against chronic hepatitis B. Substantial experience h...

journal_title：Journal of gastroenterology and hepatology

authors： Liaw YF

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:A nitroxide radical, 4-hydroxyl-2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPOL), is directly reduced to hydroxylamine by ascorbic acid (AsA). Ascorbic acid is oxidized to dehydroascorbic acid (DHA) by ascorbic acid oxidase (AAOx), and DHA is reduced to AsA by glutathione (GSH). In the present study, in vivo and...

journal_title：Journal of gastroenterology and hepatology

authors： Tada M,Yokoyama H,Ito O,Ohya H,Ogata T

更新日期：2004-01-01 00:00:00

abstract：:Eradication of Helicobacter pylori infection is known to reduce the incidence of duodenal ulcer recurrence. The most commonly used regimen for H. pylori infection is triple antimicrobial therapy for 1-2 weeks. This treatment is associated with frequent side effects and hence unsatisfactory compliance. As in vitro data...

journal_title：Journal of gastroenterology and hepatology

authors： Sung JJ,Chung SC,Hosking SW,Chan RC,Ling TK,Yung MY,Cheng AF,Li AK

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND AND AIM:The most effective schedule of proton pump inhibitor (PPI) administration and the optimal timing of endoscopy in acute peptic ulcer bleeding remain uncertain. The aim of this study was to determine the most efficient PPI regimen and optimal timing of endoscopy. METHODS:  Consecutive patients with su...

journal_title：Journal of gastroenterology and hepatology

authors： Liu N,Liu L,Zhang H,Gyawali PC,Zhang D,Yao L,Yang Y,Wu K,Ding J,Fan D

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND AIM:Bacterial metabolites produced in the bowel are potentially related to the genesis of colorectal cancer. Butyrate is protective against cancer, whereas hydrogen sulfide and oxygen free radicals can be toxic to the epithelium. The present study was designed to quantitate Eubacterium rectale, Faecaliba...

journal_title：Journal of gastroenterology and hepatology

authors： Balamurugan R,Rajendiran E,George S,Samuel GV,Ramakrishna BS

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:It has been suggested that gastric mucosal injury induced by Helicobacter pylori infection is mediated by interleukin-8 (IL-8). METHODS:We studied the effect of plaunotol, a drug extracted from the Plau-noi tree of Thailand, and reported it to be effective in the treatment of ulcers, of IL-8 secretion induc...

journal_title：Journal of gastroenterology and hepatology

authors： Takagi A,Koga Y,Aiba Y,Kabir AM,Watanabe S,Ohta-Tada U,Osaki T,Kamiya S,Miwa T

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Endoscopic resection (ER) has become an important therapeutic option for early gastric cancer (EGC). Some investigators have suggested that this indication should be extended. We aimed to compare the extended indication of ER for intramucosal EGC based on data from a large, single-center study. METHODS:We a...

journal_title：Journal of gastroenterology and hepatology

authors： Chung JW,Jung HY,Choi KD,Song HJ,Lee GH,Jang SJ,Park YS,Yook JH,Oh ST,Kim BS,Kim JH

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND AIM:Although several meta-analyses suggested that sequential therapy (SQT) is superior to standard triple therapy (STT) for the eradication of Helicobacter pylori, these results were mainly based on the studies from Italy. The aim of this study was to assess the efficacy of 10-day SQT for H. pylori infec...

journal_title：Journal of gastroenterology and hepatology

authors： Yoon H,Lee DH,Kim N,Park YS,Shin CM,Kang KK,Oh DH,Jang DK,Chung JW

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND AND AIM:Nonalcoholic steatohepatitis (NASH) is a metabolic disorder of the liver that may evolve into fibrosis or cirrhosis. Recent studies have shown reduction of experimental liver fibrosis with the use of angiotensin-converting-enzyme inhibitors or angiotensin-receptor antagonists. The aim of this study w...

journal_title：Journal of gastroenterology and hepatology

authors： Ibañez P,Solis N,Pizarro M,Aguayo G,Duarte I,Miquel JF,Accatino L,Arrese M

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:By analyzing a tumor growth of hepatocellular carcinoma (HCC) detected in sustained responders (SR) to interferon (IFN) therapy for chronic hepatitis C, we sought to determine the duration of follow up in SR that would be sufficient to detect HCC. In addition, we sought to elucidate the presence of HCC, whic...

journal_title：Journal of gastroenterology and hepatology

authors： Toyoda H,Kumada T,Honda T,Hayashi K,Katano Y,Nakano I,Hayakawa T,Fukuda Y

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND AND AIM:The purpose of this study was to describe the computed tomography (CT) findings of sorafenib-treated hepatic tumors in patients with advanced hepatocellular carcinoma and to correlate the findings to the overall survival (OS). METHODS:Twenty-eight sorafenib-treated patients who had advanced hepatoce...

journal_title：Journal of gastroenterology and hepatology

authors： Kim MJ,Choi JI,Lee JS,Park JW

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND AIM:Liver transplantation remains the best option for treating type-1 hepatorenal syndrome (HRS1). The aim of this retrospective study was to determine whether the molecular adsorbent recirculation system (MARS) can improve renal function in HRS1 patients. METHODS:Thirty-two patients with chronic liver ...

journal_title：Journal of gastroenterology and hepatology

authors： Lavayssière L,Kallab S,Cardeau-Desangles I,Nogier MB,Cointault O,Barange K,Muscari F,Rostaing L,Kamar N

更新日期：2013-06-01 00:00:00