P21-activated kinase-2 is a critical mediator of transforming growth factor-β-induced hepatoma cell migration.

abstract：:Helicobacter pylori is present in infected patients not only on the gastric epithelial cell surface but also in gastric mucus. We developed a competitive polymerase chain reaction (cPCR) method for quantitative measurement of H. pylori in gastric mucus. The aim of this study was to determine the number of H. pylori in...

journal_title：Journal of gastroenterology and hepatology

authors： Furuta T,Takashima M,Futami H,Arai H,Hanai H,Kaneko E

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:In order to evaluate the prophylactic impact of sclerotherapy of small varices in patients with cirrhosis and no endoscopic signs suggesting risk of haemorrhage, a randomized clinical trial was performed. METHODS:Seventy-one hospitalized patients met the inclusion criteria of diagnosis of cirrhosis with no ...

journal_title：Journal of gastroenterology and hepatology

authors： Strauss E,Ribeiro MF,Albano A,Honain NZ,Maffei RA Jr,Caly WR

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND AND AIM:The effect of solid debris on walled-off necrosis (WON) drainage remains unknown. Our study evaluated the role of solid debris in endoscopic ultrasound (EUS)-guided drainage of WON compared lumen-apposing metal stent (LAMS) with double-pigtail plastic stent (DPPS). METHODS:We retrospectively evaluat...

journal_title：Journal of gastroenterology and hepatology

authors： Zhu H,Xie P,Wang Y,Jin Z,Li Z,Du Y

更新日期：2020-05-04 00:00:00

abstract：:Changes in serum hyaluronic acid (HA) in 35 patients treated with interferon (IFN) were studied and the histological change in fibrosis was analysed. Serum HA levels and hepatitis C virus (HCV) RNA were followed from the start of therapy to 12 months after completion of treatment. Histological changes in pre- and post...

journal_title：Journal of gastroenterology and hepatology

authors： Yamada M,Fukuda Y,Koyama Y,Nakano I,Urano F,Katano Y,Hayakawa T

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND AND AIM:The present study aims to explore if and when acid (pH) refluxes can predict refluxes detected by multichannel intraluminal impedance (MII) studies. This correlation may indicate whether pH probe-only and MII-pH studies are interchangeable. METHODS:Prospective observational cross sectional study of ...

journal_title：Journal of gastroenterology and hepatology

authors： Misra S

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:With the prevalence of Helicobacter pylori (H. pylori) infection rapidly decreasing in Japan, endoscopic findings and dyspeptic symptoms need to be re-evaluated. METHODS:In a health check-up program, endoscopy was performed on 530 young Japanese subjects (371 men and 159 women) born in the 1970s. Helicobact...

journal_title：Journal of gastroenterology and hepatology

authors： Shimatani T,Inoue M,Iwamoto K,Hyogo H,Yokozaki M,Saeki T,Tazuma S,Horikawa Y

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND AND AIM:Studies have shown monounsaturated oleic acid to be less toxic than palmitic acid and to prevent/attenuate palmitic acid hepatocites toxicity in steatosis models in vitro. However, to what degree these effects are mediated by steatosis extent is unknown. METHODS:We evaluated whether steatosis per se...

journal_title：Journal of gastroenterology and hepatology

authors： Ricchi M,Odoardi MR,Carulli L,Anzivino C,Ballestri S,Pinetti A,Fantoni LI,Marra F,Bertolotti M,Banni S,Lonardo A,Carulli N,Loria P

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND AND AIM:We aimed to determine whether reflux- and symptom-related parameters can predict the efficacy of proton pump inhibitors (PPI) in non-erosive reflux disease (NERD). METHODS:Twenty-seven NERD patients who had experienced heartburn more than once a week within the previous month were enrolled. Intraeso...

journal_title：Journal of gastroenterology and hepatology

authors： Shimatani T,Sugimoto M,Nishino M,Adachi K,Furuta K,Ito M,Kurosawa S,Manabe N,Mannen K,Hongo M,Chiba T,Kinoshita Y,Acid-Related Symptom Research (ARS) Group.

更新日期：2012-05-01 00:00:00

abstract：:The effect of tauro-beta-muricholate (beta MC-tau) and tauro-alpha-muricholate (alpha MC-tau) on oestradiol-17 beta-glucuronide (E217G)-induced cholestasis was compared with that of tauroursodeoxycholate (UDC-tau) in rats. Like UDC-tau, alpha MC-tau and beta MC-tau infused at the rate of 0.2 mumol/min per 100 g bodywe...

journal_title：Journal of gastroenterology and hepatology

authors： Takikawa H,Sano N,Aiso M,Takamori Y,Yamanaka M

更新日期：1997-01-01 00:00:00

abstract：:The approach of a pediatric hepatologist in managing children with hepatitis C virus (HCV) differs from adult practice, because the pediatric hepatologist is dealing with the beginning of a chronic illness in which long-term outcomes will not occur for 20 or 40 years, and it is not possible to predict in the early sta...

journal_title：Journal of gastroenterology and hepatology

authors： Hardikar W

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND AND AIM:Early endoscopic intervention reduces morbidity and mortality for patients with high-risk gastrointestinal hemorrhage and gallstones causing pancreatitis or ascending cholangitis. For low-risk bleeds 'after-hours' endoscopy services allow risk stratification and early, safe discharge leading to reduc...

journal_title：Journal of gastroenterology and hepatology

authors： Gibson R,Hitchcock K,Duggan AE

更新日期：2006-03-01 00:00:00

abstract：:Gastric cancer usually shows poor sensitivity to chemotherapy, and the presence of lymph node metastases is associated with extremely poor prognosis, especially when the number of such nodes is more than 10. We report here a case of advanced gastric cancer with histopathologically confirmed metastases in 15 regional l...

journal_title：Journal of gastroenterology and hepatology

authors： Shigemitsu K,Naomoto Y,Matsuno T,Gochi A,Isozaki H,Tanaka N

更新日期：2001-05-01 00:00:00

abstract：:The focus on colorectal neoplasia has led to an exponential increase in the use of colonoscopy in many countries. Although colonoscopy facilitates the diagnosis and treatment of colonic disease, there are public health issues that include access, training, diagnostic accuracy, complications and additions to health-car...

journal_title：Journal of gastroenterology and hepatology

authors： Roberts-Thomson IC,Teo E

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND AND AIM:Crohn's disease (CD) is a chronic inflammatory bowel disease (IBD) of unknown etiology. We aimed to identify the etiological agent of CD using a molecular cloning strategy that was particularly focused on identifying agents causing immune abnormalities and infectious agents. METHODS:We constructed a...

journal_title：Journal of gastroenterology and hepatology

authors： Iizuka M,Nakagomi O,Nanjo H,Chiba M,Fukushima T,Sugita A,Sagara S,Horie Y,Watanabe S

更新日期：2012-08-01 00:00:00

abstract：:The most common functional disorder of the biliary tract and pancreas relates to the activity of the Sphincter of Oddi. The Sphincter of Oddi is a small smooth muscle sphincter strategically placed at the junction of the bile duct, pancreatic duct, and duodenum. The sphincter controls flow of bile and pancreatic juice...

journal_title：Journal of gastroenterology and hepatology

authors： Toouli J

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND AND AIM:Fucosylated alpha-fetoprotein (AFP-L3) is known to be a marker of poor prognosis in patients with hepatocellular carcinoma (HCC). However, it has been difficult to measure AFP-L3 under low AFP (≤ 20 ng/mL). The aim of this study was to elucidate the role of AFP-L3 in HCC patients with low AFP conditi...

journal_title：Journal of gastroenterology and hepatology

authors： Nouso K,Kobayashi Y,Nakamura S,Kobayashi S,Takayama H,Toshimori J,Kuwaki K,Hagihara H,Onishi H,Miyake Y,Ikeda F,Shiraha H,Takaki A,Iwasaki Y,Kobashi H,Yamamoto K

更新日期：2011-07-01 00:00:00

abstract：:Better understanding of hepatitis B virus (HBV) replication and the natural history and immunopathogenesis of chronic hepatitis B, together with the introduction of effective agents with different mechanisms of action, is the basis for better therapeutic strategies against chronic hepatitis B. Substantial experience h...

journal_title：Journal of gastroenterology and hepatology

authors： Liaw YF

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND AND AIM:Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that plays a significant role in tumor development. SPARC has been indicated that promotes tumorigenesis, metastasis, and poor prognosis in prostate cancer and lung cancer. Therefore, we sought to investigate the mol...

journal_title：Journal of gastroenterology and hepatology

authors： Jiang X,Liu F,Wang Y,Gao J

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND AND AIM:The differentiation between Crohn's disease (CD) and tuberculosis (TB) of the intestine can be difficult in areas where both diseases occur. The present study examined histological criteria that would enable the diagnosis in mucosal biopsies. METHODS:Colonoscopic biopsies from 33 patients with TB an...

journal_title：Journal of gastroenterology and hepatology

authors： Pulimood AB,Peter S,Ramakrishna B,Chacko A,Jeyamani R,Jeyaseelan L,Kurian G

更新日期：2005-05-01 00:00:00

abstract：:Acute suppurative cholangitis is one of the common causes of acute abdomen in Taiwan. Emergency decompression is a life-saving procedure if patients fail to respond to antibiotic treatment. From July 1988 to June 1991, 224 patients were encountered with concomitant bile duct stones and cholangitis; 40 were brought to ...

journal_title：Journal of gastroenterology and hepatology

authors： Lin XZ,Chang KK,Shin JS,Lin CY,Lin PW,Yu CY,Chou TC

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND AIM:Monotherapy has been proven insufficient in achieving sustained control of chronic hepatitis B. We aimed to assess the efficacy of combined sequential administration of lamivudine and pegylated interferon alfa-2b in patients with hepatitis Be antigen (HBeAg)-negative chronic hepatitis B. METHODS:Eig...

journal_title：Journal of gastroenterology and hepatology

authors： Vassiliadis T,Tziomalos K,Patsiaoura K,Zagris T,Giouleme O,Soufleris K,Grammatikos N,Theodoropoulos K,Mpoumponaris A,Dona K,Zezos P,Nikolaidis N,Orfanou-Koumerkeridou E,Balaska A,Eugenidis N

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND AND AIM:Liver fibrosis is an established determinant of prognosis and therapy in chronic hepatitis B (CHB). The role of fibroscan in assessing fibrosis in CHB remains unclear. Present study was designed to correlate fibroscan with liver biopsy and determine whether fibroscan can avoid liver biopsy in patient...

journal_title：Journal of gastroenterology and hepatology

authors： Goyal R,Mallick SR,Mahanta M,Kedia S,Shalimar,Dhingra R,Sharma H,Das P,Datta Gupta S,Panda S,Acharya SK

更新日期：2013-11-01 00:00:00

abstract：:Forty-six patients with primary biliary cirrhosis from a single centre were studied in a randomized placebo-controlled trial to determine the effectiveness of ursodeoxycholic acid (UDCA) over a 2 year period. The two groups were well-matched at baseline. For each parameter, by calculating the difference between the me...

journal_title：Journal of gastroenterology and hepatology

authors： Turner IB,Myszor M,Mitchison HC,Bennett MK,Burt AD,James OF

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Lung injury is an important target for the systemic inflammatory response associated with intestinal ischemia/reperfusion (I/R). In the present study, the role of interleukin (IL)-18 in the development of acute pulmonary injury induced by intestinal I/R and its possible mechanism in relation to the ...

journal_title：Journal of gastroenterology and hepatology

authors： Yang YJ,Chen SH,Ge XR

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND AND AIM:To evaluate the optimal dosage of rabeprazole for proton-pump inhibitor (PPI) testing of gastroesophageal reflux disease (GERD) and to test the influence of cytochrome P450 (CYP) 2C19 polymorphism in a population with a high prevalence of people who metabolize PPI poorly. METHODS:In this randomized,...

journal_title：Journal of gastroenterology and hepatology

authors： Lee YC,Lin JT,Wang HP,Chiu HM,Wu MS

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND AND AIM:At the same time that Helicobacter pylori prevalence is declining in Western countries, immigrants from developing countries with high H. pylori prevalence have settled in Western urban areas. Actual epidemiological data on H. pylori in a migrant community may help in realizing a more selective appro...

journal_title：Journal of gastroenterology and hepatology

authors： den Hollander WJ,Holster IL,den Hoed CM,van Deurzen F,van Vuuren AJ,Jaddoe VW,Hofman A,Perez Perez GI,Blaser MJ,Moll HA,Kuipers EJ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Primary biliary cirrhosis (PBC) might be complicated by osteoporosis, whose etiology remains unknown but seems to be multifactorial. Prevalence rates of 30% to 60% for distal renal tubular acidosis (DRTA) have been reported in PBC patients, generally as incomplete DRTA. Although it is undisputed tha...

journal_title：Journal of gastroenterology and hepatology

authors： Farias AQ,Gonçalves LL,Cançado EL,Seguro AC,Campos SB,Abrantes-Lemos CP,Carrilho FJ

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND AND AIM:Safety and efficacy data on endoscopic treatment of duodenal neoplasm are limited. We suggest the technical feasibility of endoscopic procedures by evaluating the results of endoscopic treatment for nonampullary duodenal adenoma and adenocarcinoma. METHODS:Forty-five patients who underwent endoscopi...

journal_title：Journal of gastroenterology and hepatology

authors： Seo JY,Hong SJ,Han JP,Jang HY,Myung YS,Kim C,Lee YN,Ko BM

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND AND AIM:Recent studies have shown that imbalance between tumor-infiltrating interleukin (IL)-17(+) T cells and regulatory T cells (Tregs) is an important regulator of progression in various cancers, but little is known regarding this imbalance in hepatocellular carcinoma (HCC). This study explored the role o...

journal_title：Journal of gastroenterology and hepatology

authors： Huang Y,Wang F,Wang Y,Zhu Z,Gao Y,Ma Z,Xu R,Du Z

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Low-grade erosive esophagitis (i.e. Los Angeles grade A) is the most predominant type of esophagitis in Japan. It is unclear whether all the mucosal breaks detected by conventional endoscopy are indicative of esophageal mucosal erosion. Hospital-based, cross-sectional, cross-over, observational stud...

journal_title：Journal of gastroenterology and hepatology

authors： Amano Y,Yamashita H,Koshino K,Ohshima T,Miwa H,Iwakiri R,Fujimoto K,Manabe N,Haruma K,Kinoshita Y

更新日期：2008-07-01 00:00:00