Three-dimensional ultrastructure of normal rat hepatocytes by quick-freezing and deep-etching method.

abstract：BACKGROUND AND AIMS:We identified patients with nonalcoholic fatty liver disease (NAFLD) to determine the predictive value of serum markers to diagnose histological steatohepatitis (NASH). METHODS:Demographic, serological, radiological and histological variables on 95 consecutive patients with NAFLD were recorded. The...

journal_title：Journal of gastroenterology and hepatology

authors： Malik R,Chang M,Bhaskar K,Nasser I,Curry M,Schuppan D,Byrnes V,Afdhal N

更新日期：2009-04-01 00:00:00

abstract：AIM:To investigate the factors affecting the outcome of fulminant hepatic failure (FHF) in children in relation to hepatitis B virus (HBV) infection. METHODS:Retrospective review of a total of 94 cases (61 males and 33 females, aged from 1 month to 15 years) recruited from nine tertiary referral centers in Taiwan from...

journal_title：Journal of gastroenterology and hepatology

authors： Chan PC,Chen HL,Kong MS,Huang FC,Lee HC,Lin CC,Liu CC,Lee IH,Wu TC,Wu SF,Ni YH,Hsu HY,Chang MH

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND AND AIM:Locoregional therapies for hepatocellular carcinoma (HCC) are considered to confer a survival advantage, however, the patient group that should be targeted is not clearly defined. This study aimed to determine the impact on survival of locoregional therapies compared with supportive care, within prog...

journal_title：Journal of gastroenterology and hepatology

authors： Mahady SE,Charlton B,Fitzgerald P,Koorey DJ,Perry JF,Waugh RC,McCaughan GW,Strasser SI

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND AND AIM:Endoscopic resection is highly effective treatment option for rectal neuroendocrine tumors (NETs) as they usually present as small localized tumors. However, there are no well-established surveillance strategies following endoscopic resection. We established our own protocol for the surveillance of r...

journal_title：Journal of gastroenterology and hepatology

authors： Chung HG,Goh MJ,Kim ER,Hong SN,Kim TJ,Chang DK,Kim YH

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND AND AIM:Our aim was to determine associations between metabolic risk factors and erosive esophagitis. METHODS:In this retrospective case-control study, diagnosis of erosive esophagitis was based on the Los Angeles classification. Endoscopic findings in subjects with erosive esophagitis were reviewed by two ...

journal_title：Journal of gastroenterology and hepatology

authors： Chua CS,Lin YM,Yu FC,Hsu YH,Chen JH,Yang KC,Shih CH

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:Colonic mucosal defects might be a route for bacterial invasion into the portal system, with subsequent hematogenous spread to the liver. We retrospectively investigated the results of colonoscopy and the clinical characteristics of patients with pyogenic liver abscess of colonic origin. METHODS:A t...

journal_title：Journal of gastroenterology and hepatology

authors： Jeong SW,Jang JY,Lee TH,Kim HG,Hong SW,Park SH,Kim SG,Cheon YK,Kim YS,Cho YD,Kim JO,Kim BS,Lee EJ,Kim TH

更新日期：2012-02-01 00:00:00

abstract：:In order to identify proguanylin-secreting cells, we have raised an antiserum against the synthetic fragment of human proguanylin (1-15) and have examined the proguanylin-positive cells in the human and rat gastrointestinal tract by immunohistochemical methods. Numerous proguanylin (1-15)-immunoreactive cells were fou...

journal_title：Journal of gastroenterology and hepatology

authors： Ieda H,Naruse S,Furuya S,Ozaki T,Ando E,Nokihara K,Hori S,Kitagawa M,Hayakawa T

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Mongolian gerbils are frequently used to study Helicobacter pylori-induced gastritis and its consequences. The presence of some gastric flora with a suppressive effect on H. pylori suggests inhibitory microflora against H. pylori infection. The aim of the present study was to analyze the microflora ...

journal_title：Journal of gastroenterology and hepatology

authors： Zaman C,Osaki T,Hanawa T,Yonezawa H,Kurata S,Kamiya S

更新日期：2010-05-01 00:00:00

abstract：AIMS:To investigate the relations between the formation of pigment gallstone and the function of the intestinal mucosal barrier, as well as the underlying mechanism. METHODS:Eighty guinea pigs were randomly divided into three groups in which they were respectively given normal diet, gallstone-causing diet, and gallsto...

journal_title：Journal of gastroenterology and hepatology

authors： Su Y,Wu S,Fan Y,Jin J,Zhang Z

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND AIM:Although endoscopic ultrasound-guided fine-needle biopsy is widely applied, there is no clear consensus on the optimal biopsy technique. We described a modified wet suction technique (MWEST) with the aim to compare the efficacy and safety between MWEST and the dry suction technique (DST). METHODS:In...

journal_title：Journal of gastroenterology and hepatology

authors： Tong T,Tian L,Deng M,Liu Y,Yang Y,Yin H,Long X,Pan S,Yang Z,Luo W,Nie K,Meng X,Xiao M,Wu X,Zhang C,Wang X

更新日期：2020-12-08 00:00:00

abstract：BACKGROUND:A daily injection of glycyrrhizin (Stronger Neo-Minophagen C (SNMC) containing 40 mg glycyrrhizin in a 20 mL ampoule) lowers alanine aminotransferase (ALT) levels in patients with chronic viral hepatitis. METHODS:The therapeutic effects of intermittent administration of SNMC three times a week for 12 weeks ...

journal_title：Journal of gastroenterology and hepatology

authors： Miyake K,Tango T,Ota Y,Mitamura K,Yoshiba M,Kako M,Hayashi S,Ikeda Y,Hayashida N,Iwabuchi S,Sato Y,Tomi T,Funaki N,Hashimoto N,Umeda T,Miyazaki J,Tanaka K,Endo Y,Suzuki H

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND AND AIM:Albumin-bilirubin (ALBI) grade was developed as a new method to assess hepatic function. Sorafenib has been confirmed to be effective in improving survival in patients with advanced hepatocellular carcinoma (HCC). In this study, we investigated the impact of ALBI grade versus Child-Pugh classificatio...

journal_title：Journal of gastroenterology and hepatology

authors： Tada T,Kumada T,Toyoda H,Tsuji K,Hiraoka A,Michitaka K,Deguchi A,Ishikawa T,Imai M,Ochi H,Joko K,Shimada N,Tajiri K,Hirooka M,Koizumi Y,Hiasa Y,Tanaka J

更新日期：2019-06-01 00:00:00

abstract：:Lauren's intestinal type of gastric cancer was proposed to be dependent on long-term environmental factors and is always preceded by chronic premalignant change. A cohort study was performed and demonstrated an increased cancer risk of gastric remnant after gastric surgery for benign disease. It is generally believed ...

journal_title：Journal of gastroenterology and hepatology

authors： Lo SS,Tsay SH,Wu CW,Hsieh MC,Li AF,Lui WY

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND AND AIMS:The CLOtest and other rapid urease detection kits are widely used in the endoscopic diagnosis of Helicobacter pylori. A new formulation CLOtest has been developed with the goal of obtaining a positive result more rapidly. The aims of this study were to validate the sensitivity and specificity of the...

journal_title：Journal of gastroenterology and hepatology

authors： Viiala CH,Windsor HM,Forbes GM,Chairman SO,Marshall BJ,Mollison LC

更新日期：2002-02-01 00:00:00

abstract：:This study examined Na+/H+ ion exchange of caecal and colonic mucus. Two distinct Na+/H+ ion exchange populations of caecal mucus were identified, one group being a cation exchanger and the other an anion exchanger, suggesting that caecal mucus has ampholyte properties responsive to changing physical and chemical prop...

journal_title：Journal of gastroenterology and hepatology

authors： Duncan CE,Tasman-Jones C

更新日期：1992-01-01 00:00:00

abstract：:One of the characteristic features of the majority of pancreatic ductal adenocarcinomas is an abundant desmoplastic/stromal reaction. Until recently, this stroma had received little attention from researchers studying the pathogenesis of pancreatic cancer, with most of the research focus resting on the biology of tumo...

journal_title：Journal of gastroenterology and hepatology

authors： Apte MV,Wilson JS

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Prostaglandin analogs have the pharmacologic effect of speeding up small intestinal transit (SIT). It remains unknown whether some gut peptides also mediate this enhancement. We studied the effect of misoprostol on rat SIT and looked at the role of vasoactive intestinal polypeptide (VIP) release dur...

journal_title：Journal of gastroenterology and hepatology

authors： Chang FY,Doong ML,Chen TS,Lee SD,Wang PS

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND AND AIM:Epimorphin is suggested to play a key role in the morphogenesis of epithelial cells. We focused on epimorphin and attempted to clarify the relationship between expression of this molecule and inflammatory bowel disease (IBD). METHODS:Colonic specimens were taken from 23 patients with ulcerative coli...

journal_title：Journal of gastroenterology and hepatology

authors： Shirasaka T,Iizuka M,Yukawa M,Hirai Y,Horie Y,Itou H,Kon-No S,Fukushima T,Watanabe S

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Acute graft-versus-host disease (GVHD) occurring within 100 days post-transplant is one of critical factors influencing prognosis in transplant recipients. Among cases of GVHD of the gastrointestinal (GI) tract, GVHD rarely affects the upper GI. In this study, we retrospectively examined the frequen...

journal_title：Journal of gastroenterology and hepatology

authors： Nomura K,Iizuka T,Kaji D,Yamamoto H,Kuribayashi Y,Kimura R,Yamada A,Furuhata T,Yamashita S,Kikuchi D,Matsui A,Mitani T,Ogawa O,Hoteya S,Ota Y,Taniguchi S,Kaise M

更新日期：2014-11-01 00:00:00

abstract：:To study the short- and long-term outcomes of acute hepatitis C, three groups of patients were enrolled. Of 26 patients with acute hepatitis C, 18 (69%) maintained HCV viraemia and 8 had cleared virus naturally at 12 months after the onset. Normalization of ALT was seen in all 8 patients with acute resolving hepatitis...

journal_title：Journal of gastroenterology and hepatology

authors： Tanaka E,Kiyosawa K

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND AND AIM:Serum cancer antigen (CA) 125 elevation has been reported in patients with liver disease, but it is poorly characterized. The present study aimed to evaluate the range of serum and ascitic CA 125 levels in patients with liver cirrhosis and to explore possible factors associated with CA 125 elevation....

journal_title：Journal of gastroenterology and hepatology

authors： Xiao WB,Liu YL

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND AND AIM:The prevalence of ulcerative colitis (UC) is increasing steadily in Japan. In Western countries, a bimodal distribution, with UC onset peaks in youth and middle age, is observed, and smoking cessation is reported as a risk factor for UC. However, there are few reports on a bimodal distribution of ons...

journal_title：Journal of gastroenterology and hepatology

authors： Takahashi H,Matsui T,Hisabe T,Hirai F,Takatsu N,Tsurumi K,Kanemitsu T,Sato Y,Kinjyo K,Yano Y,Takaki Y,Nagahama T,Yao K,Washio M

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The immunogenetic basis of autoimmune diseases has become more and more evident. We have analyzed the human leukocyte antigen (HLA) associations with type-1 autoimmune hepatitis (AIH) among patients from western India. METHODS:In 20 patients and 120 healthy controls, polymerase chain reaction ampli...

journal_title：Journal of gastroenterology and hepatology

authors： Shankarkumar U,Amarapurkar DN,Kankonkar S

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND AND AIM:A recent study in Indian subjects suggested common variants in apolipoprotein C3 (APOC3) (T-455C at rs2854116 and C-482T at rs2854117) to contribute to non-alcoholic fatty liver disease (NAFLD), plasma apoC3 and triglyceride concentrations. Our aim was to determine the contribution of genetic variati...

journal_title：Journal of gastroenterology and hepatology

authors： Hyysalo J,Stojkovic I,Kotronen A,Hakkarainen A,Sevastianova K,Makkonen J,Lundbom N,Rissanen A,Krauss RM,Melander O,Orho-Melander M,Yki-Järvinen H

更新日期：2012-05-01 00:00:00

abstract：:Following the development of tests for hepatitis C virus and hepatitis E virus infection, it became clear that there remained cases of hepatitis that were non-A-E. Such cases provided impetus for the search for additional hepatitis viruses and, by using molecular techniques, several candidates were identified. An ente...

journal_title：Journal of gastroenterology and hepatology

authors： Bowden S

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND AND AIM:Non-invasive markers are essential to assess the progression of chronic liver diseases to fibrosis/ cirrhosis and the effectiveness of therapeutic strategies. The aim of this study was to evaluate the ability of non-invasive markers to identify significant fibrosis, severe fibrosis, and cirrhosis in ...

journal_title：Journal of gastroenterology and hepatology

authors： Sheptulina A,Shirokova E,Nekrasova T,Blum H,Ivashkin V

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Direct-acting antivirals (DAAs) rapidly clear hepatitis C virus (HCV), but the lipid dynamics after DAA treatment remain unknown. Low-density lipoprotein (LDL) cholesterolemia is the predicting factor for the onset and death of atherosclerotic cardiovascular diseases. Thus, in this study, we examined the fre...

journal_title：Journal of gastroenterology and hepatology

authors： Morihara D,Ko YL,Shibata K,Yamauchi R,Fukuda H,Tsuchiya N,Fukunaga A,Kunimoto H,Iwashita H,Takata K,Tanaka T,Sakurai K,Inomata S,Yokoyama K,Nishizawa S,Takeyama Y,Irie M,Shakado S,Sohda T,Sakisaka S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND AND AIM:Tobacco smoking is a risk factor for gastrointestinal disorders, causing mucosal damage and impairing immune responses. However, smoking has been found to be protective against ulcerative colitis (UC). Human leukocyte antigen (HLA) is a major susceptibility locus for UC, and HLA-DRB1*15:02 has the st...

journal_title：Journal of gastroenterology and hepatology

authors： Lee HS,Kim K,Jung S,Hong M,Kim BM,Yoo DS,Moon JW,Baek J,Hwang SW,Park SH,Yang SK,Han B,Song K,Ye BD

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Studies of eradication of Helicobacter pylori and subsequent resolution of H. pylori-related gastritis, have focused mainly on medium and long-term change following eradication therapies. Results from those studies have shown that both acute and chronic inflammatory changes found in gastric mucosa eventually...

journal_title：Journal of gastroenterology and hepatology

authors： Chen W,Shu D,Wilson IR,Tie A,Chadwick VS

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND AND AIM:We recently conducted a randomized placebo-controlled trial on the efficacy and safety of rikkunshito, a standardized Japanese herbal medicine, for the treatment of functional dyspepsia (FD). The present post-hoc study aimed to evaluate the differences in clinical characteristics between responders a...

journal_title：Journal of gastroenterology and hepatology

authors： Togawa K,Matsuzaki J,Kobayakawa M,Fukushima Y,Suzaki F,Kasugai K,Nishizawa T,Naito Y,Hayakawa T,Kamiya T,Andoh T,Yoshida H,Tokura Y,Nagata H,Mori M,Kato K,Hosoda H,Takebayashi T,Miura S,Uemura N,Joh T,Hibi T,S

更新日期：2016-02-01 00:00:00