Exogenous 8-hydroxydeoxyguanosine ameliorates liver fibrosis through the inhibition of Rac1-NADPH oxidase signaling.

abstract：BACKGROUND AND AIM:The incidence of colorectal cancer (CC) is increasing in many Asian countries, but decreasing in western countries. The present study examined the local incidence of CC in the past few decades. METHODS:A population based study, using data from Hong Kong (HK) Cancer Registry, was carried out to exami...

journal_title：Journal of gastroenterology and hepatology

authors： Yee YK,Gu Q,Hung I,Tan VP,Chan P,Hsu A,Pang R,Lam CS,Wong BC

更新日期：2010-05-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small non-coding RNAs of 19-23 nucleotides that negatively regulate gene expression through binding to the 3'-untranslated regions of target messenger RNAs (mRNAs). Although the miRNA family constitutes only a minor fraction of the human genome, they hold fundamental importance in diverse physio...

journal_title：Journal of gastroenterology and hepatology

authors： Law PT,Wong N

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Non-alcoholic fatty liver disease (NAFLD) is an emerging problem in the Asia-Pacific region. However, its prevalence and risk factors in Asian (especially South Asian) communities is poorly studied. In this study, the aim was to determine the community prevalence and risk factors for NAFLD among adu...

journal_title：Journal of gastroenterology and hepatology

authors： Dassanayake AS,Kasturiratne A,Rajindrajith S,Kalubowila U,Chakrawarthi S,De Silva AP,Makaya M,Mizoue T,Kato N,Wickremasinghe AR,de Silva HJ

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIM:HFE mutations, a common cause of hereditary hemochromatosis (HH), are reportedly associated with hepatic iron overload, severe liver fibrosis, and good response to interferon treatment in European patients with chronic hepatitis C (CHC). HH shows ethnicity-based differences and little is known about ...

journal_title：Journal of gastroenterology and hepatology

authors： Ishizu Y,Katano Y,Honda T,Hayashi K,Ishigami M,Itoh A,Hirooka Y,Nakano I,Goto H

更新日期：2012-06-01 00:00:00

abstract：:Hepatitis E, caused by infection with hepatitis E virus (HEV), is a common cause of acute hepatitis in areas with poor sanitation. The virus has four genotypes with one serotype: genotypes 1 and 2 exclusively infect humans, whereas genotypes 3 and 4 also infect other animals, particularly pigs. In endemic areas, both ...

journal_title：Journal of gastroenterology and hepatology

authors： Aggarwal R,Naik S

更新日期：2009-09-01 00:00:00

abstract：:The Korean College of Helicobacter and Upper Gastrointestinal Research first developed guidelines for the diagnosis and treatment of Helicobacter pylori (H. pylori) infection in 1998, and revised guidelines were proposed in 2009 by the same group. Although the revised guidelines were based on a comprehensive review of...

journal_title：Journal of gastroenterology and hepatology

authors： Kim SG,Jung HK,Lee HL,Jang JY,Lee H,Kim CG,Shin WG,Shin ES,Lee YC,Korean College of Helicobacter and Upper Gastrointestinal Research.

更新日期：2014-01-01 00:00:00

abstract：:A case of persistent ileitis following the refashioning of a Kock ileal pouch into a Brooke ileostomy for severe pouchitis is reported. Preserving the terminal ileum by a salvage procedure may not be a safe alternative to pouch excision with the formation of a new end ileostomy in the surgical management of pouchitis ...

journal_title：Journal of gastroenterology and hepatology

authors： de Silva HJ,Mortensen NJ

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND AND AIM:The European evidence-based guidelines (EEG) and American College of Gastroenterology Guidelines (ACGG) have been published to guide the management of pancreatic cystic lesions. We aim to evaluate the value of both guidelines in predicting advanced pancreatic cystic lesions (A-PCLs) with preoperative...

journal_title：Journal of gastroenterology and hepatology

authors： Sun L,Wang W,Wang Y,Jiang F,Peng L,Jin G,Jin Z

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Biliary disease is one of the most common causes of acute pancreatitis in adults; however, this cause and outcome in children have rarely been described in the literature. Therefore, the present study was conducted to evaluate the role of biliary disease as a cause of acute pancreatitis in children....

journal_title：Journal of gastroenterology and hepatology

authors： Choi BH,Lim YJ,Yoon CH,Kim EA,Park YS,Kim KM

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND AIM:The Baveno VI Consensus recommends repeating examination in patients with high liver stiffness measurement (LSM) by transient elastography to reduce false-positive diagnosis of advanced liver disease. We tested whether repeating transient elastography can increase the overall diagnostic accuracy. ME...

journal_title：Journal of gastroenterology and hepatology

authors： Chow JC,Wong GL,Chan AW,Shu SS,Chan CK,Leung JK,Choi PC,Chim AM,Chan HL,Wong VW

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIM:The ability to detect early squamous neoplasia of the esophagus can be enhanced considerably by iodine staining during endoscopic examination; however, there has been no study on distinguishing high-grade intra-epithelial squamous neoplasia from low-grade dysplasia by endoscopic examination. We assum...

journal_title：Journal of gastroenterology and hepatology

authors： Shimizu Y,Omori T,Yokoyama A,Yoshida T,Hirota J,Ono Y,Yamamoto J,Kato M,Asaka M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:One-third of patients with exacerbations of ulcerative colitis (UC) require colectomy and 1% die. Although several studies have reported parameters associated with failure of medical treatment, studies using multivariate analysis of various predictors are scanty. METHODS:Demographic, clinical and laboratory...

journal_title：Journal of gastroenterology and hepatology

authors： Kumar S,Ghoshal UC,Aggarwal R,Saraswat VA,Choudhuri G

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Habitual alcohol intake is known to aggravate the clinical outcome of hepatitis C virus (HCV)-related chronic liver diseases and to increase the risk of hepatocellular carcinoma. METHODS:To investigate the possible mechanism of these effects by alcohol, we examined 31 cases of HCV-related chronic liver dise...

journal_title：Journal of gastroenterology and hepatology

authors： Takahashi K,Takahashi T,Takahashi S,Watanabe K,Boku S,Matsui S,Arai F,Asakura H

更新日期：2001-04-01 00:00:00

abstract：:Helicobacter pylori, non-steroidal anti-inflammatory drugs, family history, blood group O, hyperpepsinogenaemia A, alcohol and smoking have been reported to be risk factors for peptic ulcer disease. The strength of causal risk factors may differ in different populations. In 215 Japanese and 493 Dutch employees of simi...

journal_title：Journal of gastroenterology and hepatology

authors： Schlemper RJ,van der Werf SD,Vandenbroucke JP,Biemond I,Lamers CB

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND AND AIM:Controversy continues as to whether nutcracker esophagus (NE) is a 'real' manometric disease due to its poor correlation with clinical symptoms such as chest pain or dysphagia. While new NE criteria were proposed in a recent study, that study included NE patients both with and without gastroesophagea...

journal_title：Journal of gastroenterology and hepatology

authors： Jung KW,Jung HY,Yoon IJ,Kim DH,Chung JW,Oh HC,Choi KS,Choi KD,Song HJ,Lee GH,Kim JH

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND/AIMS:Psychological factors and subtle histopathological changes have been implicated in irritable bowel syndrome (IBS). The aims of the present study were to investigate whether the numbers of enterochromaffin (EC) cells, mast cells, and lamina propria T lymphocytes are altered in IBS, and evaluate the relat...

journal_title：Journal of gastroenterology and hepatology

authors： Lee KJ,Kim YB,Kim JH,Kwon HC,Kim DK,Cho SW

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND AND AIM:A substantial number of patients with gastroesophageal reflux disease show symptomatic resistance to high-dose proton pump inhibitors. In those cases, prokinetics are possible candidates for treatment. The aim of the present study was to determine whether mosapride, a prokinetic agent, stimulates eso...

journal_title：Journal of gastroenterology and hepatology

authors： Koshino K,Adachi K,Furuta K,Ohara S,Morita T,Nakata S,Tanimura T,Miki M,Kinoshita Y

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND AND AIM:Since the advent of direct-acting antiviral (DAA) therapy, the total eradication of hepatitis C virus has been achievable with the recovery of hepatic reserve after achievement of sustained virologic response (SVR). Hence, here, we examined the factors affecting the recovery of hepatic reserve. METH...

journal_title：Journal of gastroenterology and hepatology

authors： Nakajima T,Karino Y,Hige S,Suii H,Tatsumi R,Yamaguchi M,Arakawa T,Kuwata Y,Hasegawa T,Toyota J

更新日期：2020-09-29 00:00:00

abstract：:High circulating serum immunoglobulin G4 (IgG4) levels have been proposed as a marker of autoimmune pancreatitis (AIP). The aim of the present study was to review the data existing in the English literature on the usefulness of the IgG4 serum levels in the diagnosis and follow up of patients with AIP. A total of 159 p...

journal_title：Journal of gastroenterology and hepatology

authors： Morselli-Labate AM,Pezzilli R

更新日期：2009-01-01 00:00:00

abstract：:The exact pathogenesis of centrilobular necrosis following congestion of the liver is still unknown. We reviewed the clinical data related to systemic circulatory disturbance and histopathology of the liver and the gut in 320 autopsy subjects. Congestion of the liver alone was associated only with atrophy and loss of ...

journal_title：Journal of gastroenterology and hepatology

authors： Shibayama Y,Urano T,Asaka S,Hashimoto K,Nakata K

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Few data were available on the optimal diagnostic strategy for Chinese patients with hematochezia. We aimed to evaluate the impact of age and distal colonic findings on the yield of diagnostic strategies in young Chinese patients with hematochezia. METHODS:Consecutive outpatients aged less than 50 ...

journal_title：Journal of gastroenterology and hepatology

authors： Liou JM,Lin JT,Wang HP,Huang SP,Lin JW,Wu MS

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND AND AIM:This study aimed to estimate the time to precursor progression and to identify significant predicators. METHODS:One hundred thirty-three precursor and 311 normal cases detected in a population-based screening were surveyed for 5.5 years. Precursor progression was defined as worsening of dysplasia or...

journal_title：Journal of gastroenterology and hepatology

authors： Wen D,Zhang L,Wang X,Li Y,Ma C,Liu X,Zhang J,Wen X,Yang Y,Zhang F,Wang S,Shan B

更新日期：2015-12-01 00:00:00

abstract：:Bioactive food chemicals are substances present in food that are capable of interacting with living cells causing changes in physiological functions. Salicylic acid (SA), a plant hormone involved in plant immune response, is one such bioactive food chemical. Aspirin, a commercially available SA, might play beneficial ...

journal_title：Journal of gastroenterology and hepatology

authors： Malakar S

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND AND AIM:Patients with non-alcoholic fatty liver disease (NAFLD) have an increased risk of atherosclerosis and alanine aminotransferase (ALT) is associated with insulin resistance independently of metabolic factors. The aim of the present study was to investigate whether NAFLD patients with ALT elevation had ...

journal_title：Journal of gastroenterology and hepatology

authors： Wang CC,Lin SK,Tseng YF,Hsu CS,Tseng TC,Lin HH,Wang LY,Kao JH

更新日期：2009-08-01 00:00:00

abstract：:Following partial hepatectomy (PH), there is a rapid and highly orchestrated series of biochemical events which occur prior to cellular proliferation. Some of these events are presumably intimately linked with the eventual regeneration of the liver, whereas others are likely to be stress related or required for the co...

journal_title：Journal of gastroenterology and hepatology

authors： Brenner DA

更新日期：1998-09-01 00:00:00

abstract：AIM:To evaluate the characterization of liver hemangiomas and malignant tumors using power Doppler sonography before and after intravenous injection of a sonocontrast agent. METHODS:Forty-five patients with 57 liver tumors (22 hemangiomas, 24 metastases, 10 hepatocellular carcinomas (HCC) and one cholangiocellular car...

journal_title：Journal of gastroenterology and hepatology

authors： Karabacakoglu A,Karakose S,Cil AS,Kaya A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Endoscopic ultrasonography (EUS) is a useful tool for the evaluation of gastric wall infiltration including gastric lymphoma. The aims of this study were to characterize gastric low-grade mucosa-associated lymphoid tissue (MALT) lymphoma according to EUS findings and to evaluate the role of a miniat...

journal_title：Journal of gastroenterology and hepatology

authors： Yeh HZ,Chen GH,Chang WD,Poon SK,Yang SS,Lien HC,Chang CS,Chou G

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND AND AIMS:It is well known that endotoxemia, which is caused by a bacterial infection, can exacerbate acute pancreatitis, whereas pancreatitis-associated protein (PAP) has the ability to induce bacterial aggregation. Pancreatitis-associated protein is supposed to protect the tissue from infection during infla...

journal_title：Journal of gastroenterology and hepatology

authors： Wang X,Wang B,Wu J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Intestinal endotoxin (lipopolysaccharide) is thought to contribute to liver injury in both alcoholic and nonalcoholic steatohepatitis (NASH). Tumor necrosis factor alpha (TNFalpha) is an important mediator of this process and is considered central to the inflammatory response in NASH. This study aim...

journal_title：Journal of gastroenterology and hepatology

authors： Kirsch R,Clarkson V,Verdonk RC,Marais AD,Shephard EG,Ryffel B,de la M Hall P

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Endoscopic obliteration of esophageal varices by endoscopic variceal ligation (EVL) is an effective form of secondary prophylaxis. However, there is no consensus regarding the technical aspects of EVL for secondary prophylaxis. The present study compares the technical aspects of EVL (frequency of sessions,...

journal_title：Journal of gastroenterology and hepatology

authors： Harewood GC,Baron TH,Song LM

更新日期：2006-01-01 00:00:00