Effect of immunisation with cancer procoagulant on the growth of Walker 256 carcinosarcoma cells in rats.

abstract：:Gastrointestinal (GIT) cancers represent the third common cancers worldwide, characterized by rapid progression and higher mortality rate. Matrix metalloproteinases (MMPs) play an important role in cancer metastases. The present study was conducted to estimate and evaluate the role of MMP-7, -9, -10 and -12 and TGF β1...

journal_title：Clinical and experimental medicine

authors： El-Ashmawy NE,Khedr NF,Mansour MG,Al-Ashmawy GM

更新日期：2020-11-01 00:00:00

abstract：:Primary biliary cirrhosis (PBC) is a slowly progressive autoimmune disease of unknown mechanism. We established a PBC animal model by injecting C57BL/6 mice with polyinosinic-polycytidylic acid sodium (polyI:C) to investigate the therapeutic effect of bone marrow-derived mesenchymal stem cells (BM-MSC) on this model. ...

journal_title：Clinical and experimental medicine

authors： Wang D,Zhang H,Liang J,Gu Z,Ma X,Huang J,Lin J,Hou Y,Lu L,Sun L

更新日期：2011-03-01 00:00:00

abstract：:Studies have demonstrated cytomegalovirus (CMV) DNA particles in restenotic lesions in atherosclerotic coronary arteries. We have shown that high (>1:800) anti-CMV IgG antibody titers in the serum are associated with active coronary disease and with post coronary angioplasty restenosis. In this study we assessed the a...

journal_title：Clinical and experimental medicine

authors： Blum A,Peleg A,Weinberg M

更新日期：2003-11-01 00:00:00

abstract：:Endotoxin is known to cause acute lung injury (ALI). Here, we investigated the effects and mechanisms of recombinant human bone morphogenetic protein-2 (rhBMP-2) on pulmonary arteriole remodeling in endotoxin-induced ALI in rats. Sixty Wistar rats were randomly divided into 3 groups (n = 20). Control group was infused...

journal_title：Clinical and experimental medicine

authors： Wang K,Gong J,Pei L,Shan S,Tan W

更新日期：2013-08-01 00:00:00

abstract：:Behcet's disease is a recurrent multisystem vasculitis that can affect any organ or system, but was originally described as orogenital ulcerations and uveitis. Specific criteria have been proposed for diagnosis and identification of affected organs by different national authorities. Behcet's disease is proposed to be ...

journal_title：Clinical and experimental medicine

authors： Al-Mutawa SA,Hegab SM

更新日期：2004-12-01 00:00:00

abstract：:Increased expression of progranulin (PGRN) has been reported in some hematological cancers, but limited information regarding its significance in acute lymphoblastic leukemia (ALL) is available. This study involved 60 subjects (40 de novo adult ALL patients and 20 controls). Serum PGRN level was measured by enzyme-lin...

journal_title：Clinical and experimental medicine

authors： El-Ghammaz AMS,Azzazi MO,Mostafa N,Hegab HM,Mahmoud AA

更新日期：2020-05-01 00:00:00

abstract：:Recent findings suggest that cell and gene transplantation in the infarcted myocardium may improve heart function. The aim of the study was to investigate the mechanism involved in improving heart function following the co-injection of adipose-derived stem cells (ADSCs) and basic fibroblast growth factor (bFGF) in a r...

journal_title：Clinical and experimental medicine

authors： Wang B,Ma X,Zhao L,Zhou X,Ma Y,Sun H,Yang Y,Chen B

更新日期：2016-11-01 00:00:00

abstract：:The rat is an established model for studying intestinal adaptations following abdominal surgery. In the study of functional and morphological adaptations of the small intestine, it is helpful to estimate the mucosal surface area. In order to simplify measurements and calculation we developed a new mathematical model f...

journal_title：Clinical and experimental medicine

authors： Kisielinski K,Willis S,Prescher A,Klosterhalfen B,Schumpelick V

更新日期：2002-11-01 00:00:00

abstract：:The aim of this work was to investigate the presence of the RHD gene in fetal cells obtained from amniotic fluid. We studied 65 samples of amniotic fluid, 11 from RhD-negative mothers sensitized with anti-D alloantibodies. The fetal origin of the DNA was confirmed with the analysis of 1 VNTR locus and 3 STR loci in DN...

journal_title：Clinical and experimental medicine

authors： Cotorruelo C,Biondi C,García Borrás S,Di Mónaco R,Racca A

更新日期：2002-07-01 00:00:00

abstract：:Recently, Th17 cell-associated responses have received growing attention; however, the role of IL-22 (a cytokines also produced by Th17 cells) in the pathogenesis of systemic lupus erythematosus (SLE) has not been widely explored. In this study, we analyze the frequencies of IL-22-positive CD4+/CD8+ T cells in periphe...

journal_title：Clinical and experimental medicine

authors： Qin WZ,Chen LL,Pan HF,Leng RX,Zhai ZM,Wang C,Li RJ,Wang S,Wang HP,Ye DQ

更新日期：2011-12-01 00:00:00

abstract：:Anti-inflammatory cytokine and its serological detection may have an important role in the process of cardiovascular and cerebrovascular diseases. We investigated whether serum interleukin-10 (IL-10) is associated with cerebral infarction or not in the general population. Identified comprehensive searching was perform...

journal_title：Clinical and experimental medicine

authors： Diao ZY,Wang CL,Qi HS,Jia GY,Yan CZ

更新日期：2016-05-01 00:00:00

abstract：:The thrombin generation potential is an in vitro measure for the capacity of an individual to generate thrombin and recognized as a reflection of a hypo- or hypercoagulable status. Measurement of the in vivo thrombin activity, however, may be of clinical significance. We evaluated a new assay for in vivo thrombin acti...

journal_title：Clinical and experimental medicine

authors： Königsbrügge O,Koder S,Riedl J,Panzer S,Pabinger I,Ay C

更新日期：2017-05-01 00:00:00

abstract：:To evaluate potency and safety of 14-day bismuth-furazolidone quadruple regimens and to compare efficacies of five proton pump inhibitors (PPIs) for the initial eradication of Helicobacter pylori (H. pylori), 175 eligible patients were enrolled and randomly assigned to 14-day quadruple regimens consisting of bismuth (...

journal_title：Clinical and experimental medicine

authors： Chen L,He J,Wang L,Ge Q,Chu H,Chen Y,Chen X,Long Y,Deng Y,He H,Li A,Chen S

更新日期：2018-11-01 00:00:00

abstract：:Mixed-phenotype acute leukemia (MPAL) is the infrequent type of acute leukemia characterized by immunophenotypic and/or cytochemical features of both lineages, but the diagnosis of this disease still is a challenge. In this study, we analyzed immunophenotyping, cytochemistry and frequency of MPAL patients to better di...

journal_title：Clinical and experimental medicine

authors： Poopak B,Khosravi A,Bahoush-Mehdiabadi G,Madani T,Khodadi E,Farahani Z,Vahedi AA,Khosravipour G,Poopak P,Poopak AH

更新日期：2018-11-01 00:00:00

abstract：:Hyperhomocysteinemia is an independent risk factor for vascular disease, frequently observed in patients with severe renal impairment. Hyperhomocysteinemia has never been considered as a possible risk factor in renal artery stenosis. We investigated plasma folate and vitamin B12, methylenetetrahydrofolate reductase (M...

journal_title：Clinical and experimental medicine

authors： Olivieri O,Friso S,Trabetti E,Girelli D,Pizzolo F,Faccini G,Stranieri C,Pignatti PF,Corrocher R

更新日期：2001-12-01 00:00:00

abstract：:Triglyceride-rich lipoproteins contain both apolipoproteins E (ApoE) and C-III (ApoC-III), which show opposite functional properties. The relationships between the ApoE (epsilon2/epsilon3/epsilon4) gene polymorphism and ApoC-III/ApoE ratio has never been investigated. A large population (n=552) of cardiovascular patie...

journal_title：Clinical and experimental medicine

authors： Olivieri O,Martinelli N,Bassi A,Trabetti E,Girelli D,Pizzolo F,Friso S,Pignatti PF,Corrocher R

更新日期：2007-12-01 00:00:00

abstract：:Immunophenotypic characterization of the leukemic cells has been widely used as a tool for diagnosis, classification and prognosis of leukaemia. A total of 192 Chinese patients with acute myeloid leukemia (AML) were immunophenotyped by flow cytometry using a panel of monoclonal antibodies. Among the 192 patients enrol...

journal_title：Clinical and experimental medicine

authors： Tong H,Lu C,Zhang J,Liu Z,Ma Y

更新日期：2009-06-01 00:00:00

abstract：:The melphalan-prednisone regimen has been considered as standard therapy for patients with multiple myeloma (MM) for many years. Recently, high-dose chemotherapy with stem-cell support has extended progression-free survival and increased overall survival, and it is now considered conventional therapy in younger patien...

journal_title：Clinical and experimental medicine

authors： Merchionne F,Perosa F,Dammacco F

更新日期：2007-09-01 00:00:00

abstract：:B-cell chronic lymphocytic leukemia (B-CLL) is one of the most common leukemias among the elderly and, despite many efforts, still stays incurable. Recent studies point to the microenvironment as the critical factor providing leukemic lymphocytes with pro-survival signals. Thus, the neighboring cells appear to be a pe...

journal_title：Clinical and experimental medicine

authors： Filip AA,Ciseł B,Wąsik-Szczepanek E

更新日期：2015-02-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a very common head and neck cancer in southern china. Despite advances in surgical and chemotherapeutic approaches, its prognosis is still not promising. Hedgehog signaling pathway was reported to be involved in a number of cancers including head and neck. However, it remains unclear ...

journal_title：Clinical and experimental medicine

authors： Yue Y,Zhong W,Pei G,Xiao B,Zhang G,Jiang F,Zhang J,Chen C,Yang P,Dang H,Chang H

更新日期：2013-11-01 00:00:00

abstract：:Arginase activity was measured in serum and biopsy from healthy individuals and colorectal cancer patients. Arginase activity in tumor samples (87 +/- 7.7 U/g tissue) was significantly higher than in controls (40.7 +/- 3.3 U/g tissue). However, serum arginase activity did not show any significant change in both groups...

journal_title：Clinical and experimental medicine

authors： del Ara RM,González-Polo RA,Caro A,del Amo E,Palomo L,Hernández E,Soler G,Fuentes JM

更新日期：2002-05-01 00:00:00

abstract：:Alpha1-adrenoceptor antagonists (alpha1-blockers) are currently used as first-line drugs for the treatment of benign prostatic hyperplasia (BPH). However, cases of BPH are often encountered in which the efficacy of alpha1-blockers decreases and switching to surgical treatment is required. One factor responsible for th...

journal_title：Clinical and experimental medicine

authors： Imamura T,Ishii K,Kanda H,Arase S,Yoshio Y,Hori Y,Soga N,Kise H,Arima K,Sugimura Y

更新日期：2010-06-01 00:00:00

abstract：:The cross-sectional study was conducted to examine hepatic function via liver enzymes/proteins assessments, along with the estimation of an inflammatory response from C-reactive protein (CRP)-which is a liver-synthesized protein. The liver function tests with aspartate aminotransferase (AST), alanine aminotransferase ...

journal_title：Clinical and experimental medicine

authors： Shahid S,Masood K

更新日期：2018-02-01 00:00:00

abstract：:Takayasu arteritis (TAK) is a rare granulomatous vasculitis of unknown etiology that mainly affects the aorta and its major branches. The aim is to describe the clinical features, diagnostic procedures, pathogenesis, and management of TAK in a longitudinal cohort of patients recruited within a single region of souther...

journal_title：Clinical and experimental medicine

authors： Dammacco F,Cirulli A,Simeone A,Leone P,Pulli R,Angiletta D,Rubini G,Di Palo A,Vacca A,Dammacco R

更新日期：2020-10-07 00:00:00

abstract：:Bronchoalveolar lavage (BAL) is a useful procedure for differential diagnosis of interstitial lung diseases (ILDs) and for identification of granulomatous lung diseases. We investigated a panel of biomarkers from BAL fluid of ILD patients to evaluate their utility in differentiating ILDs. Bronchoscopy with BAL was per...

journal_title：Clinical and experimental medicine

authors： d'Alessandro M,Carleo A,Cameli P,Bergantini L,Perrone A,Vietri L,Lanzarone N,Vagaggini C,Sestini P,Bargagli E

更新日期：2020-05-01 00:00:00

abstract：:Common variable immunodeficiency (CVID) is a heterogeneous group of disorders, characterized by hypogammaglobulinemia and increased susceptibility to infections, autoimmunity and malignancies. This study was performed to analyze the Mannose-binding lectin (MBL) polymorphisms in Iranian patients with CVID. Thirty-five ...

journal_title：Clinical and experimental medicine

authors： Aghamohammadi A,Foroughi F,Rezaei N,Dianat S,Solgi G,Amirzargar AA

更新日期：2009-12-01 00:00:00

abstract：:Chronic infection with hepatitis C virus (HCV) is a leading cause of liver-related morbidity and mortality throughout the world. Although reliable figures regarding the global prevalence of HCV infection are wanting, it is likely that HCV prevalence will continue to increase. Injection drug use is the most important s...

journal_title：Clinical and experimental medicine

authors： Herrine SK,Rossi S,Navarro VJ

更新日期：2006-03-01 00:00:00

abstract：:Diabetes is one of the most common and challenging health problems. Studies in several nations show that polymorphisms within the transcription factor 7-like 2 genes could be associated with type 2 diabetes (T2D). Therefore, a case-control study was conducted to find the association between SNP rs7903146 and T2D in ou...

journal_title：Clinical and experimental medicine

authors： Palizban A,Nikpour M,Salehi R,Maracy MR

更新日期：2012-06-01 00:00:00

abstract：:Familial hypercholesterolaemia is a genetic disorder characterised by high low-density lipoprotein (LDL) cholesterol concentrations, which frequently gives rise to premature coronary artery disease (CAD). The clinical expression of familial hypercholesterolaemia is highly variable even in patients carrying the same LD...

journal_title：Clinical and experimental medicine

authors： Pitsavos C,Choumerianou DM,Skoumas J,Maumus S,Stefanadis C,Dedoussis GV,Visvikis-Siest S

更新日期：2005-12-01 00:00:00

abstract：:The sensitivity of the alkaline comet assay for the evaluation of baseline and treatment-induced DNA damage in white blood cells of breast cancer patients receiving adjuvant chemotherapy according to three conventional anthracycline- and cyclophosphamide-containing protocols was investigated. Additionally, baseline DN...

journal_title：Clinical and experimental medicine

authors： Kopjar N,Milas I,Garaj-Vrhovac V,Gamulin M

更新日期：2006-12-01 00:00:00