Abstract:
:The part played by MHC antigens on lymphocyte homing has been investigated by inducing modifications of their expression on lymphoid cells. A significant, though moderate, enhancement of H-2 antigen expression has been observed following in vitro treatment of lymphocytes with alpha-IFN. A decrease has been obtained after in vivo treatment of mice with chloramphenicol. These rather moderate alterations of H-2 density (ca. 20-30%, as determined by cytofluorometry) did not induced changes of lymphocyte capacity to home into the different lymphoid organs.
journal_name
Immunobiologyjournal_title
Immunobiologyauthors
Navarro J,El Ansary M,Royo C,de Maeyer E,Touraine JLdoi
10.1016/S0171-2985(84)80073-Xsubject
Has Abstractpub_date
1984-12-01 00:00:00pages
404-13issue
5eissn
0171-2985issn
1878-3279pii
S0171-2985(84)80073-Xjournal_volume
167pub_type
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