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Androgen-dependent peptides of the rat ventral prostate nuclear envelope.

Abstract：

:Nuclear envelope peptides of the rat ventral prostate in the molecular weight region 18,400 to 19,400 show marked androgen dependence. After castration these peptides disappear. Re-administration of testosterone restores them. They were not extracted by 0.1 M NaCl or 5% HClO4 but were partially extracted by 0.35 M NaCl and 1% Triton. These peptides were not present in rat liver nuclear envelopes. As these androgen-dependent non-histone peptides have similar characteristics to androgen-dependent peptides identified in the prostate nucleus, we conclude that the nuclear peptides are at least partially localized to the nuclear envelope.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Venkatraman JT,Howell GM,Lefebvre YA

doi

10.1016/0006-291x(84)90564-3

subject

Has Abstract

pub_date

1984-12-14 00:00:00

pages

469-74

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(84)90564-3

journal_volume

125

pub_type

杂志文章

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